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Original Research

The Inhibitory Efficiencies of Geraniol as an Anti-Inflammatory, Antioxidant, and Antibacterial, Natural Agent Against Methicillin-Resistant Staphylococcus aureus Infection in vivo

, , , , &
Pages 2991-3000 | Published online: 05 Aug 2021

References

  • CromwellGL. Why and how antibiotics are used in swine production. Anim Biotechnol. 2002;13:7–27. doi:10.1081/ABIO-12000576712212945
  • Van BoeckelTP, BrowerC, GilbertM, et al. Global trends in antimicrobial use in food animals. Proc Natl Acad Sci. 2015;112:5649–5654. doi:10.1073/pnas.150314111225792457
  • ShorrAF. Epidemiology of staphylococcal resistance. Clin Infect Dis. 2007;45:S171–S176. doi:10.1086/51947317712743
  • Aires-de-sousaM. Methicillin-resistant Staphylococcus aureus among animals: current overview. Clin Microbiol Infect. 2017;23(6):373–380. doi:10.1016/j.cmi.2016.11.00227851997
  • KarinH, LisaB, DamerPB, et al. Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs. Vet Res. 2018;49(1):64. doi:10.1186/s13567-018-0560-830060757
  • LeNT, HoDV, DoanTQ, et al. Biological activities of essential oils from leaves of Paramignya trimera (Oliv.) Guillaum and Limnocitrus littoralis (Miq.) Swingle. Antibiotics (Basel). 2020;9(4):207. doi:10.3390/antibiotics9040207
  • DonaduMG, Peralta-RuizY, UsaiD. Colombian essential oil of Ruta graveolens against nosocomial antifungal resistant Candida strains. J Fungi. 2021;7(5):383. doi:10.3390/jof7050383
  • LeNT, DonaduMG, HoDV, et al. Biological activities of essential oil extracted from leaves of Atalantia sessiflora Guillauminin Vietnam. J Infect Dev Ctries. 2020;14(9):1054–1064. doi:10.3855/jidc.1246933031096
  • YuL, PengF, XieJ, et al. Pharmacological properties of geraniol – a review. Planta Med. 2019;85(1):48–55. doi:10.1055/a-0750-690730308694
  • QiF, YanQ, ZhengZ, et al. Geraniol and geranyl acetate induce potent anticancer effects in colon cancer Colo-205 cells by inducing apoptosis, DNA damage and cell cycle arrest. J BUON. 2018;23(2):29745075.
  • WangJ, SuB, ZhuH, et al. Protective effect of geraniol inhibits inflammatory response, oxidative stress and apoptosis in traumatic injury of the spinal cord through modulation of NF-kappaB and p38 MAPK. Exp Ther Med. 2016;12:3607–3613. doi:10.3892/etm.2016.385028105094
  • PereiraFO, MendesJM, LimaIO, et al. Antifungal activity of geraniol and citronellol, two monoterpenes alcohols, against Trichophyton rubrum involves inhibition of ergosterol biosynthesis. Pharm Biol. 2015;53:228–234. doi:10.3109/13880209.2014.91329925414073
  • SunFH, LongNN, WangXM, et al. In vitro antibacterial activity of geraniol against methicillin-resistant Staphylococcus aureus. Chin J Antibiot. 2018;(7):921–926.
  • YaoM, LiZ, WangX, et al. Advances in the research of commonly used antibiotic substitutes as feed additive. Feed Indus. 2019;40(08):61–64.
  • WangM, RenP, LiuH, et al. Investigating antibiotics, antibiotic resistance genes in soil, groundwater and vegetables in relation to agricultural field-applicated with lincomycin mycelial residues compost. Sci Total Environ. 2021;777(4):146066. doi:10.1016/j.scitotenv.2021.14606633677290
  • FariaL, LisboaTP, CamposN, et al. Electrochemical methods for the determination of antibiotic residues in milk: a critical review. Anal Chim Acta. 2021;1173:338569. doi:10.1016/j.aca.2021.33856934172150
  • HartJ, PhillipsP. What out-of-hours antibiotic prescribing practices are contributing to antibiotic resistance: a literature review. Br Paramedic J. 2020;4(4):25–33. doi:10.29045/14784726.2020.12.4.4.25
  • HagrasM, MohammadH, MandourMS, et al. Investigating the antibacterial activity of biphenylthiazoles against methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA andVRSA). J Med Chem. 2017;60(9):4074–4085. doi:10.1021/acs.jmedchem.7b0039228436655
  • SergelidisD, AngelidisAS. Methicillin-resistant Staphylococcus aureus: a controversial food-borne pathogen. Lett Appl Microbiol. 2017;64(6):409–418. doi:10.1111/lam.1273528304109
  • PaulOL, EmilyLH, KellyLC, et al. Treatment strategies for persistent methicillin-resistant Staphylococcus aureus bacteraemia. J Clin Pharm Ther. 2018;43(5):614–625. doi:10.1111/jcpt.1274330003555
  • KeshavS, PreranaK, RimaDS, et al. MILK symposium review: improving control of mastitis in dairy animals in Nepal. J Dairy Sci. 2020;103(11):9740–9747. doi:10.3168/jds.2020-1831433076185
  • ShariatiA, DadashiM, MoghadamMT, et al. Clinical isolates: a systematic review and meta-analysis. Sci Rep. 2020;10:12689. doi:10.1038/s41598-020-69058-z32728110
  • Al-BderyA, MohammadGJ, HussenB. Vancomycin and linezolid resistance among multidrug-resistant Staphylococcus aureus clinical isolates and interaction with neutrophils. Gene Rep. 2020;21:100804. doi:10.1016/j.genrep.2020.100804
  • OlearoF, BothA, CamposCB, et al. Emergence of Linezolid-resistance in Vancomycin-resistant Enterococcus faecium ST117 associated with increased Linezolid-consumption. Int J Med Microbiol. 2021;311(2):151477. doi:10.1016/j.ijmm.2021.15147733524636
  • BryantAE, BayerCR, AldapeMJ, et al. Emerging erythromycin and clindamycin resistance in group A streptococci: efficacy of linezolid and tedizolid in experimental necrotizing infection. J Glob Antimicrob Resist. 2020;22:601–607. doi:10.1016/j.jgar.2020.04.03232408046
  • Solorzano-SantosF, Miranda-NovalesMG. Essential oils from aromatic herbs as antimicrobial agents. Curr Opin Biotechnol. 2012;23(2):136–141. doi:10.1016/j.copbio.2011.08.00521903378
  • HuangY, YangXL, NiYH, et al. Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells. Drug Des Devel Ther. 2018;12:2897–2903. doi:10.2147/DDDT.S145702
  • MazzarelloV, GaviniE, RassuG, et al. Clinical assessment of new topical cream containing two essential oils combined with tretinoin in the treatment of acne. Clin Cosmet Investig Dermatol. 2020;13:233–239. doi:10.2147/CCID.S236956
  • BaracA, DonaduM, UsaiD, et al. Antifungal activity of Myrtus communis against Malassezia sp. isolated from the skin of patients with pityriasis versicolor. Infection. 2018;46(2):253–257. doi:10.1007/s15010-017-1102-429159502
  • DonaduMG, UsaiD, MarchettiM, et al. Antifungal activity of oils macerates of North Sardinia plants against Candida species isolated from clinical patients with candidiasis. Nat Prod Res. 2020;34(22):3280–3284. doi:10.1080/14786419.2018.155717530676066
  • CannasS, UsaiD, PinnaA, et al. Essential oils in ocular pathology: an experimental study. J Infect Dev Ctries. 2015;9(6):650–654. doi:10.3855/jidc.684226142676
  • BarbaraP, AlessandroD, LucaM, et al. Geraniol pharmacokinetics, bioavailability and its multiple effects on the liver antioxidant and xenobiotic-metabolizing enzymes. Front Pharmacol. 2018;9:18. doi:10.3389/fphar.2018.0001829422862
  • VerhoefJ, MattssonE. The role of cytokines in gram-positive bacterial shock. Trends Microbiol. 1995;3(4):136–140. doi:10.1016/S0966-842X(00)88902-77613754
  • CavaillonJM, Adib-ConquyM, FittingC, et al. Cytokinecascade in sepsis. Scand J Infect Dis. 2003;35(9):535544. doi:10.1080/00365540310015935
  • LowyFD. Staphylococcus aureus infections. N Engl J Med. 1998;339(8):520–532. doi:10.1056/NEJM1998082033908069709046
  • SongY, DuX, LiT, et al. Phenotypic and molecular characterization of Staphylococcus aureus recovered from different clinical specimens of inpatients at a teaching hospital in Shanghai between 2005 and 2010. J Med Microbiol. 2013;62(2):274–282. doi:10.1099/jmm.0.050971-023118474
  • TokajianST, KhalilPA, JabbourD, et al. Molecular characterization of Staphylococcus aureus in Lebanon. Epidemiol Infect. 2010;138(5):707–712. doi:10.1017/S095026881000044020202283
  • NadigS, RamachandraRS, ArakereG. Epidemic meticillin-resistant Staphylococcus aureus (EMRSA-15) variants detected in healthy and diseased individuals in India. J Med Microbiol. 2010;59(7):815–821. doi:10.1099/jmm.0.017632-020339016
  • HalliwellB. Antioxidants in human health and disease. Annu Rev Nutr. 1996;16:33–50. doi:10.1146/annurev.nu.16.070196.0003418839918
  • TramutolaA, LanzillottaC, PerluigiM, et al. Oxidative stress, protein modification and Alzheimer disease. Brain Res Bull. 2017;133:88–96. doi:10.1016/j.brainresbull.2016.06.00527316747
  • ZhangZ, YuCX. Effect of melatonin on learning and memory impairment induced by aluminum chloride and its mechanism. Yao Xue Xue Bao. 2002;37(9):682–686.12567890
  • Feillet-CoudrayC, SutraT, FouretG, et al. Oxidative stress in rats fed a high-fat high-sucrose diet and preventive effect of polyphenols: involvement of mitochondrial and NAD(P)H oxidase systems. Free Radic Biol Med. 2009;46(5):624–632. doi:10.1016/j.freeradbiomed.2008.11.02019135522
  • JayachandranM, ChandrasekaranB, NamasivayamN. Geraniol attenuates fibrosis and exerts anti-inflammatory effects on diet induced atherogenesis by NF-kappaB signaling pathway. Eur J Pharmacol. 2015;762:102–111. doi:10.1016/j.ejphar.2015.05.03926004525
  • LewandowskiL, KepinskaM, MilnerowiczH. Inhibition of copper-zinc superoxide dismutase activity by selected environmental xenobiotics. Environ Toxicol Pharmacol. 2018;58:105–113. doi:10.1016/j.etap.2017.12.02229310006
  • CardosoBR, HareDJ, BushAI, et al. Glutathione peroxidase 4: a new player in neurodegeneration?Mol Psychiatry. 2017;22(3):328–335. doi:10.1038/mp.2016.19627777421
  • KanekoY, YanagiharaK, MiyazakiY, et al. Effects of DQ-113, a new quinolone, against methicillin- and vancomycin-resistant Staphylococcus aureus caused hematogenous pulmonary infections in mice. Antimicrob Agents Chemother. 2003;47(12):3694–3698. doi:10.1128/AAC.47.12.3694-3698.200314638467
  • KiharaR, YanagiharaK, MorinagaY, et al. Potency of SMP-601, a novel carbapenem, in hematogenous murine bronchopneumonia caused by methicillin-resistant and vancomycin-intermediate Staphylococcus aureus. Antimicrob Agents Chemother. 2008;52(6):2163–2168. doi:10.1128/AAC.01532-0718391033
  • LiY, WangN, JiangY. Geraniol protects against lipopolysaccharide and D-galactosamine-induced fulminant hepatic failure by activating PPAR gamma. Microb Pathog. 2019;128:7–12. doi:10.1016/j.micpath.2018.11.05430550845