Clonal Dissemination of Multiple Carbapenemase Genes in Carbapenem-Resistant Enterobacterales Mediated by Multiple Plasmids in China

References

• GajdácsM, BátoriZ, ÁbrókM, LázárA, BuriánK. Characterization of resistance in Gram-negative urinary isolates using existing and novel indicators of clinical relevance: a 10-year data analysis. Life (Basel). 2020;10:16. doi:10.3390/life10020016
   Web of Science ®Google Scholar
• LutgringJD. Carbapenem-resistant Enterobacteriaceae: an emerging bacterial threat. Semin Diagn Pathol. 2019;36:182–186. doi:10.1053/j.semdp.2019.04.01131056277
   PubMed Web of Science ®Google Scholar
• ZhangY, WangQ, YinY, et al. Epidemiology of carbapenem-resistant Enterobacteriaceae infections: report from the China CRE Network. Antimicrob Agents Chemother. 2018;62. doi:10.1128/aac.01882-17
   Web of Science ®Google Scholar
• LiJ, ZouMX, WangHC, et al. An outbreak of infections caused by a Klebsiella pneumoniae ST11 clone coproducing Klebsiella pneumoniae carbapenemase-2 and rmtB in a Chinese teaching hospital. Chin Med J (Engl). 2016;129:2033–2039. doi:10.4103/0366-6999.18904927569227
   PubMed Web of Science ®Google Scholar
• GajdácsM. The concept of an ideal antibiotic: implications for drug design. Molecules. 2019;24(5):892. doi:10.3390/molecules24050892
   PubMed Web of Science ®Google Scholar
• GajdácsM, AlbericioF. Antibiotic resistance: from the bench to patients. Antibiotics (Basel). 2019;8. doi:10.3390/antibiotics8030129
   Web of Science ®Google Scholar
• World Health Organization (WHO). Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics. WHO; Geneva, Switzerland: 2017. Available from:  https://www.who.int/medicines/publications/WHO-PPL-Short_Summary_25Feb-ET_NM_WHO.pdf
   Google Scholar
• KazmierczakKM, KarlowskyJA, de JongeBLM, StoneGG, SahmDF. Epidemiology of carbapenem resistance determinants identified in meropenem-nonsusceptible Enterobacterales collected as part of a global surveillance program, 2012 to 2017. Antimicrob Agents Chemother. 2021;65:e0200020. doi:10.1128/aac.02000-2033972241
   PubMed Web of Science ®Google Scholar
• GoodmanKE, SimnerPJ, TammaPD, MilstoneAM. Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE). Expert Rev Anti Infect Ther. 2016;14:95–108. doi:10.1586/14787210.2016.110694026535959
   PubMed Web of Science ®Google Scholar
• GajdácsM, ÁbrókM, LázárA, et al. Detection of VIM, NDM and OXA-48 producing carbapenem resistant Enterobacterales among clinical isolates in Southern Hungary. Acta Microbiol Immunol Hung. 2020;67(4):209–215. doi:10.1556/030.2020.01181
   Web of Science ®Google Scholar
• HansenGT. Continuous evolution: perspective on the epidemiology of carbapenemase resistance among Enterobacterales and other Gram-negative bacteria. Infect Dis Ther. 2021;10:75–92. doi:10.1007/s40121-020-00395-233492641
   PubMed Web of Science ®Google Scholar
• LiX, MaW, QinQ, et al. Nosocomial spread of OXA-232-producing Klebsiella pneumoniae ST15 in a teaching hospital, Shanghai, China. BMC Microbiol. 2019;19:235. doi:10.1186/s12866-019-1609-131660869
   PubMed Web of Science ®Google Scholar
• ZhuangZ, LvL, LuJ, LinJ, LiuJH. Emergence of Klebsiella pneumoniae and Enterobacter cloacae producing OXA-48 carbapenemases from retail meats in China, 2018. J Antimicrob Chemother. 2019;74(12):3632–3634. doi:10.1093/jac/dkz39431730159
   PubMed Web of Science ®Google Scholar
• LiJ, YuT, TaoXY, et al. Emergence of an NDM-5-producing Escherichia coli sequence type 410 clone in infants in a children’s hospital in China. Infect Drug Resist. 2020;13:703–710. doi:10.2147/idr.s24487432184632
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing. 30th ed. CLSI supplement M100. Wayne, PA: Clinical and Laboratory Standards Institute; 2020
   Google Scholar
• LiJ, ZouM, DouQ, et al. Characterization of clinical extensively drug-resistant Pseudomonas aeruginosa in the Hunan province of China. Ann Clin Microbiol Antimicrob. 2016;15:35. doi:10.1186/s12941-016-0148-y27215335
   PubMed Web of Science ®Google Scholar
• PoirelL, WalshTR, CuvillierV, NordmannP. Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis. 2011;70:119–123. doi:10.1016/j.diagmicrobio.2010.12.00221398074
   PubMed Web of Science ®Google Scholar
• TenoverFC, ArbeitRD, GoeringRV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233–2239. doi:10.1128/jcm.33.9.2233-2239.19957494007
   PubMed Web of Science ®Google Scholar
• LiJ, HuangZY, YuT, et al. Isolation and characterization of a sequence type 25 carbapenem-resistant hypervirulent Klebsiella pneumoniae from the mid-south region of China. BMC Microbiol. 2019;19:219. doi:10.1186/s12866-019-1593-531533609
   PubMed Web of Science ®Google Scholar
• DiancourtL, PassetV, VerhoefJ, GrimontPA, BrisseS. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol. 2005;43:4178–4182. doi:10.1128/jcm.43.8.4178-4182.200516081970
   PubMed Web of Science ®Google Scholar
• SuiW, ZhouH, DuP, et al. Whole genome sequence revealed the fine transmission map of carbapenem-resistant Klebsiella pneumonia isolates within a nosocomial outbreak. Antimicrob Resist Infect Control. 2018;7:70. doi:10.1186/s13756-018-0363-829881543
   PubMed Web of Science ®Google Scholar
• CarattoliA, ZankariE, García-FernándezA, et al. In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing. Antimicrob Agents Chemother. 2014;58:3895–3903. doi:10.1128/aac.02412-1424777092
   PubMed Web of Science ®Google Scholar
• Aguilera-AlonsoD, Escosa-GarcíaL, Saavedra-LozanoJ, CercenadoE, Baquero-ArtigaoF. Carbapenem-resistant Gram-negative bacterial infections in Children. Antimicrob Agents Chemother. 2020;64. doi:10.1128/aac.02183-19
   Web of Science ®Google Scholar
• HanR, ShiQ, WuS, et al. Dissemination of carbapenemases (KPC, NDM, OXA-48, IMP, and VIM) among carbapenem-resistant Enterobacteriaceae isolated from adult and children patients in China. Front Cell Infect Microbiol. 2020;10:314. doi:10.3389/fcimb.2020.0031432719751
   PubMed Web of Science ®Google Scholar
• ZhangM, LiJ, LuY, et al. Expanding of ST11 carbapenemase-producing Klebsiella pneumoniae subclones in a Chinese Hospital, Shenzhen, China. Infect Drug Resist. 2021;14:1415–1422. doi:10.2147/idr.s29947833880046
   PubMed Web of Science ®Google Scholar
• TóthÁ, MakaiA, JánváriL, DamjanovaI, GajdácsM, UrbánE. Characterization of a rare bla(VIM-4) metallo-β-lactamase-producing Serratia marcescens clinical isolate in Hungary. Heliyon. 2020;6:e04231. doi:10.1016/j.heliyon.2020.e0423132637682
   PubMedGoogle Scholar
• FuP, TangY, LiG, YuL, WangY, JiangX. Pandemic spread of bla(KPC-2) among Klebsiella pneumoniae ST11 in China is associated with horizontal transfer mediated by IncFII-like plasmids. Int J Antimicrob Agents. 2019;54:117–124. doi:10.1016/j.ijantimicag.2019.03.01430885806
   PubMed Web of Science ®Google Scholar
• MachulskaM, BaraniakA, ŻakI, et al. KPC-2-producing Klebsiella pneumoniae ST11 in a children’s hospital in Poland. Pol J Microbiol. 2017;66:401–404. doi:10.5604/01.3001.0010.488429319505
   PubMed Web of Science ®Google Scholar
• OteoJ, Pérez-VázquezM, BautistaV, et al. The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3. J Antimicrob Chemother. 2016;71:3392–3399. doi:10.1093/jac/dkw32127530752
   PubMed Web of Science ®Google Scholar
• QiaoF, WeiL, FengY, et al. Handwashing sink contamination and carbapenem-resistant Klebsiella infection in the intensive care unit: a prospective multicenter study. Clin Infect Dis. 2020;71:S379–s385. doi:10.1093/cid/ciaa151533367578
   PubMed Web of Science ®Google Scholar
• PatilS, ChenX, WenF. Exploring the phenotype and genotype of multi-drug resistant Klebsiella pneumoniae harbouring bla(CTX-M) group extended-spectrum β-lactamases recovered from paediatric clinical cases in Shenzhen, China. Ann Clin Microbiol Antimicrob. 2019;18:32. doi:10.1186/s12941-019-0331-z31690324
   PubMedGoogle Scholar
• ZhuW, WangX, QinJ, LiangW, ShenZ. Dissemination and stability of the bla (NDM-5)-carrying IncX3-type plasmid among multiclonal Klebsiella pneumoniae isolates. mSphere. 2020;5. doi:10.1128/mSphere.00917-20
   Web of Science ®Google Scholar
• ChenQ, ZhouJ, WuS, et al. Characterization of the IncX3 plasmid producing bla(NDM-7) from Klebsiella pneumoniae ST34. Front Microbiol. 2020;11:1885. doi:10.3389/fmicb.2020.0188532849464
   PubMedGoogle Scholar
• Pérez-VázquezM, Sola CampoyPJ, OrtegaA, et al. Emergence of NDM-producing Klebsiella pneumoniae and Escherichia coli in Spain: phylogeny, resistome, virulence and plasmids encoding blaNDM-like genes as determined by WGS. J Antimicrob Chemother. 2019;74:3489–3496. doi:10.1093/jac/dkz36631504589
   PubMedGoogle Scholar