Vancomycin Use in Posterior Lumbar Interbody Fusion of Deep Surgical Site Infection

References

• Ojo OA, Owolabi BS, Oseni AW, Kanu OO, Bankole OB. Surgical site infection in posterior spine surgery. Niger J Clin Pract. 2016;19(6):821–826. doi:10.4103/1119-3077.183237 PMID: 27811458.
   PubMed Web of Science ®Google Scholar
• Yin D, Liu B, Chang Y, Gu H, Zheng X. Management of late-onset deep surgical site infection after instrumented spinal surgery. BMC Surg. 2018;18(1):121. doi:10.1186/s12893-018-0458-4
   Web of Science ®Google Scholar
• Hey HW, Thiam DW, Koh ZS, et al. Is intraoperative local vancomycin powder the answer to surgical site infections in spine surgery? Spine. 2017;42(4):267–274. doi:10.1097/BRS.0000000000001710
   Web of Science ®Google Scholar
• Marc A, Weinstein JPM, Frank P, Cammisa FP Jr. Postoperative spinal wound infection: a review of 2391 consecutive index procedures. J Spinal Disord. 2000;13(5):422–426. doi:10.1097/00002517-200010000-00009
   Google Scholar
• Devin CJ, Chotai S, McGirt MJ, et al. Intrawound vancomycin decreases the risk of surgical site infection after posterior spine surgery: a multicenter analysis. Spine. 2018;43(1):65–71. doi:10.1097/BRS.0000000000001371
   Web of Science ®Google Scholar
• de Lissovoy G, Fraeman K, Hutchins V, Murphy D, Song D, Vaughn BB. Surgical site infection: incidence and impact on hospital utilization and treatment costs. Am J Infect Control. 2009;37:387–397. doi:10.1016/j.ajic.2008.12.010
   PubMed Web of Science ®Google Scholar
• Manoukian S, Stewart S, Graves N, et al. Bed-days and costs associated with the inpatient burden of healthcare-associated infection in the UK. J Hosp Infect. 2021;114:43–50. doi:10.1016/j.jhin.2020.12.027
   Web of Science ®Google Scholar
• Sweet FA, Roh M, Sliva C. Intrawound application of vancomycin for prophylaxis in instrumented thoracolumbar fusions: efficacy, drug levels, and patient outcomes. Spine. 2011;36(24):2084–2088.
   Web of Science ®Google Scholar
• Sono T, Fujibayashi S, Izeki M, et al. Decreased rate of surgical site infection after spinal surgery with instrumentation using bundled approach including surveillance and intrawound vancomycin application. Medicine. 2018;97(34):e12010. doi:10.1097/MD.0000000000012010
   Web of Science ®Google Scholar
• Han J, Yang Y, Lu J, et al. Sustained release vancomycin-coated titanium alloy using a novel electrostatic dry powder coating technique may be a potential strategy to reduce implant-related infection. Biosci Trends. 2017;11(3):346–354. doi:10.5582/bst.2017.01061.
   PubMed Web of Science ®Google Scholar
• Mangram AJ, Pearson ML, Pearson ML, et al. Guideline for prevention of surgical site infection, 1999. Hospital infection control practices advisory committee. Infect Control Hosp Epidemiol. 1999;20:279–280. doi:10.1086/501620
   Web of Science ®Google Scholar
• White AJ, Fiani B, Jarrah R, Momin AA, Rasouli J. Surgical site infection prophylaxis and wound management in spine surgery. Asian Spine J. 2021. doi:10.31616/asj.2020.0674
   Web of Science ®Google Scholar
• Moise PA, Smyth DS, El-Fawal N, et al. Microbiological effects of prior vancomycin use in patients with methicillin-resistant Staphylococcus aureus bacteraemia. J Antimicrob Chemother. 2008;61(1):85–90. doi:10.1093/jac/dkm445
   PubMed Web of Science ®Google Scholar
• Mendoza MC, Sonn KA, Kannan AS, et al. The effect of vancomycin powder on bone healing in a rat spinal rhBMP-2 model. J Neurosurg Spine. 2016;25(2):145–153. doi:10.3171/2015.11.SPINE15536
   Web of Science ®Google Scholar
• Philp AM, Raja S, Philp A, Newton Ede MP, Jones SW. The effect of vancomycin and gentamicin antibiotics on human osteoblast proliferation, metabolic function, and bone mineralization. Spine. 2017;42(3):202–207. doi:10.1097/BRS.0000000000001712
   Web of Science ®Google Scholar
• Goldschmidt E, Rasmussen J, Chabot JD, et al. The effect of vancomycin powder on human dural fibroblast culture and its implications for dural repair during spine surgery. J Neurosurg Spine. 2016;25(5):665–670. doi:10.3171/2016.3.SPINE151491
   Web of Science ®Google Scholar
• Koutsoumbelis S, Hughes AP, Girardi FP, et al. Risk factors for postoperative infection following posterior lumbar instrumented arthrodesis. J Bone Joint Surg Am. 2011;93(17):1627–1633. doi:10.2106/JBJS.J.00039
   PubMed Web of Science ®Google Scholar
• Zhang L, Li EN. Risk factors for surgical site infection following lumbar spinal surgery: a meta-analysis. Ther Clin Risk Manag. 2018;14:2161–2169. doi:10.2147/TCRM.S181477
   Web of Science ®Google Scholar
• Chaichana KL, Bydon M, Santiago-Dieppa DR, et al. Risk of infection following posterior instrumented lumbar fusion for degenerative spine disease in 817 consecutive cases. J Neurosurg Spine. 2014;20(1):45–52. doi:10.3171/2013.10.SPINE1364
   Web of Science ®Google Scholar
• Aoude A, Nooh A, Fortin M, et al. Incidence, predictors, and postoperative complications of blood transfusion in thoracic and lumbar fusion surgery: an analysis of 13,695 patients from the American College of Surgeons National Surgical Quality Improvement Program Database. Global Spine J. 2016;6(8):756–764. doi:10.1055/s-0036-1580736
   Google Scholar
• Lonjon G, Dauzac C, Fourniols E, et al. Early surgical site infections in adult spinal trauma: a prospective, multicentre study of infection rates and risk factors. Orthop Traumatol Surg Res. 2012;98(7):788–794. doi:10.1016/j.otsr.2012.07.006
   Web of Science ®Google Scholar
• Norris GR, Checketts JX, Scott JT, Vassar M, Norris BL, Giannoudis PV. Prevalence of deep surgical site infection after repair of periarticular knee fractures: a systematic review and meta-analysis. JAMA Netw Open. 2019;2(8):e199951. doi:10.1001/jamanetworkopen.2019.9951
   Web of Science ®Google Scholar
• Mirzashahi B, Chehrassan M, Mortazavi SMJ. Intrawound application of vancomycin changes the responsible germ in elective spine surgery without significant effect on the rate of infection: a randomized prospective study. Musculoskelet Surg. 2018;102(1):35–39. doi:10.1007/s12306-017-0490-z
   Google Scholar
• Ghobrial GM, Cadotte DW, Williams K Jr, Fehlings MG, Harrop JS. Complications from the use of intrawound vancomycin in lumbar spinal surgery: a systematic review. Neurosurg Focus. 2015;39(4):E11. doi:10.3171/2015.7.FOCUS15258
   Web of Science ®Google Scholar