Bacteriological Profiles, Antimicrobial Susceptibility Patterns, and Associated Factors in Patients Undergoing Orthopedic Surgery with Suspicion of Surgical Site Infection at Arba Minch General Hospital in Southern Ethiopia

References

• World Health Organization. Global guidelines for the prevention of surgical site infection. World Health Organization; 2016:135–136. Available from: https://www.who.int/gpsc/global-guidelines-web.pdf. Accessed May 05, 2022.
   Google Scholar
• Kisibo A, Ndume V, Semiono A, et al. Surgical site infection among patients undergone orthopaedic surgery at Muhimbili Orthopaedic Institute, Dar Es Salaam, Tanzania. East Cent Afr J Surg. 2017;22(1):49–58. doi:10.4314/ecajs.v22i1.7
   Google Scholar
• Starčević S, Munitlak S, Mijović B, Mikić D, Šuljagić V. Surgical site infection surveillance in orthopedic patients in the Military Medical Academy, Belgrade. Vojnosanit Pregl. 2015;72(6):499–504. doi:10.2298/VSP140224059S
   Web of Science ®Google Scholar
• Uçkay I, Hoffmeyer P, Lew D, Pittet D. Prevention of surgical site infections in orthopaedic surgery and bone trauma: state-of-the-art update. J Hosp Infect. 2013;84(1):5–12. doi:10.1016/j.jhin.2012.12.014
   Web of Science ®Google Scholar
• Lakshminarayana S, Chavan S, Prakash R, Sangeetha S. Bacteriological profile of orthopedic patients in a tertiary care hospital, Bengaluru. Int J Sci Res. 2013;4(6):2319–7064.
   Google Scholar
• Najjar YW, Saleh MY. Orthopedic surgical site infection: incidence, predisposing factors, and prevention. Int J Med Sci Clin Invent. 2017;4(2):2651–2661.
   Google Scholar
• Shah MQ, Zardad MS, Khan A, Ahmed S, Awan AS, Mohammad T. Surgical site infection in orthopedic implants and its common bacteria with their sensitivities to antibiotics, in open reduction internal fixation. J Ayub Med Coll Abbottabad. 2017;29(1):50–53.
   Google Scholar
• Sarangi SK, Padhi S. Bacteriological profile of post-operative orthopedic implant infections and their antibiotic sensitivity pattern in a tertiary care hospital of southern Odisha. J Dr NTR Univ Health Sci. 2019;8(2):114. doi:10.4103/JDRNTRUHS.JDRNTRUHS_48_19
   Google Scholar
• Bhat AK, Parikh NK, Acharya A. Orthopaedic surgical site infections: a prospective cohort study. Can J Infect Control. 2018;33(4):227–229.
   Google Scholar
• Abraham Y, Wamisho BL. Microbial susceptibility of bacteria isolated from open fracture wounds presenting to the err of black-lion hospital, Addis Ababa University, Ethiopia. Afr J Microbiol Res. 2009;3(12):939–951.
   Google Scholar
• Bauer L. Arthroplasty. Surgical Technologist. 2010:66. ( Available from: https://www.ast.org/pdf/314.pdf. Accessed May 5, 2022).
   Google Scholar
• Al-Mulhim FA, Baragbah MA, Sadat-Ali M, Alomran AS, Azam MQ. Prevalence of surgical site infection in orthopedic surgery: a 5-year analysis. Int Surg. 2014;99(3):264–268. doi:10.9738/INTSURG-D-13-00251.1
   PubMed Web of Science ®Google Scholar
• Hadadi A, Zehtab M, Babagolzadeh H, Ashraf H. Contributing Risk Factors for Orthopedic Device Related Infections in Sina Hospital, Tehran, Iran. Iran Red Crescent Med J. 2011;13(2):117.
   Web of Science ®Google Scholar
• Asres G, Legese M, Woldearegay G. Prevalence of multidrug resistant Bacteria in postoperative wound infections at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Arch Med. 2017;9(4):12.
   Google Scholar
• Fernandes A, Dias M. The microbiological profiles of infected prosthetic implants with an emphasis on the organisms which form biofilms. J Clin Diagnostic Res. 2013;7(2):219. doi:10.7860/JCDR/2013/4533.2732
   Google Scholar
• Ercole FF, Franco LMC, Macieira TGR, Wenceslau LCC, Hind R, Chianca TCM. Risk of surgical site infection in patients undergoing orthopedic surgery. Rev Lat Am Enfermagem. 2011;19(6):1362–1368. doi:10.1590/S0104-11692011000600012
   Web of Science ®Google Scholar
• Zimmerli W. Clinical presentation and treatment of orthopaedic implant‐associated infection. J Intern Med. 2014;276(2):111–119. doi:10.1111/joim.12233
   PubMed Web of Science ®Google Scholar
• McConoughey SJ, Howlin R, Granger JF, et al. Biofilms in periprosthetic orthopedic infections. Future Microbiol. 2014;9(8):987–1007. doi:10.2217/fmb.14.64
   PubMed Web of Science ®Google Scholar
• Okike K, Bhattacharyya T. Trends in the management of open fractures. A critical analysis. J Bone Joint Surg Am. 2006;88(12):2739–2748. doi:10.2106/JBJS.F.00146
   PubMed Web of Science ®Google Scholar
• Doshi P, Gopalan H, Sprague S, Pradhan C, Kulkarni S, Bhandari M. Incidence of infection following internal fixation of open and closed tibia fractures in India (INFINITI): a multi-centre observational cohort study. BMC Musculoskelet Disord. 2017;18(1):156. doi:10.1186/s12891-017-1506-4
   Web of Science ®Google Scholar
• Das RSA, Srivastava P, Pradhan S, Murthy R. Microbial profile and antibiotic susceptibility pattern of surgical site infections in orthopedic patients at a Tertiary hospital in Bilaspur. Int J Sci Study. 2015;3(3):47.
   Google Scholar
• Chandrika S, Kirani SK. Bacteriological spectrum of post-operative orthopedic implant infections and their antibiogram. J Krishna Inst Med Sci Univ. 2016;5(1):20–26.
   Google Scholar
• Mezemir R, Seid A, Gishu T, Demas T, Gize A. Prevalence and root causes of surgical site infections at an academic trauma and burn center in Ethiopia: a cross-sectional study. Patient Saf Surg. 2020;14(1):3. doi:10.1186/s13037-019-0229-x
   Web of Science ®Google Scholar
• Wayne PA; CLSI. Performance Standards for Antimicrobial Susceptibility Testing CLSI supplements M100. Clinical and Laboratory Standards Institute; 2020. Available from: https://www.nih.org.pk/wp-content/uploads/2021/02/CLSI-2020.pdf. Accessed May 5, 2022.
   Google Scholar
• Cheesbrough M District laboratory practice in tropical countries, part 2: Cambridge university press; 2006. Available from: https://www.medbox.org/preview/5255d6e1-05d4-41a9-beb2-02b60e695ecc/doc.pdf. Accessed May 5, 2022.
   Google Scholar
• Bergey’s. Manual of systematic bacteriology ; 2010. Available from: 10.1007/978-0-387-21609-6_13. Accessed May 5, 2022.
   Google Scholar
• Hudzicki J. Kirby-Bauer disk diffusion susceptibility test protocol. Am Soc Microbiol. 2009;8(15):55–63.
   Google Scholar
• Stepanović S, Vuković D, Hola V, et al. Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci. Apmis. 2007;115(8):891–899. doi:10.1111/j.1600-0463.2007.apm_630.x
   PubMed Web of Science ®Google Scholar
• Maksimović J, Marković-Denić L, Bumbaširević M, Marinković J, Vlajinac H. Surgical site infections in orthopedic patients: prospective cohort study. Croat Med J. 2008;49(1):58–64. doi:10.3325/cmj.2008.1.58
   PubMed Web of Science ®Google Scholar
• Shabnum M. Microbial profile and antibiotic susceptibility pattern of orthopedic infections in a tertiary care hospital: a study from South India. Int J Med Sci Public Health. 2017;6(5):838–842.
   Google Scholar
• Benazir S, Kakru DK, Khurshid S, et al. Identification, antibiotic susceptibility patterns and biofilm detection of isolates in orthopaedic implant infections. J adv med. 2018;25(5):1–12. doi:10.9734/JAMMR/2018/38988
   Google Scholar
• Cheng H, Clymer JW, Chen BP, et al. Prolonged operative duration is associated with complications: a systematic review and meta-analysis. J Surg Res. 2018;1(229):134–144. doi:10.1016/j.jss.2018.03.022
   Web of Science ®Google Scholar
• Mama M, Abdissa A, Sewunet T. Antimicrobial susceptibility pattern of bacterial isolates from wound infection and their sensitivity to alternative topical agents at Jimma University Specialized Hospital, South-West Ethiopia. Ann Clin Microbiol Antimicrob. 2014;13(1):1–10. doi:10.1186/1476-0711-13-14
   Web of Science ®Google Scholar
• Mengesha RE, Kasa BG, Saravanan M, Berhe DF, Wasihun AG. Aerobic bacteria in post-surgical wound infections and pattern of their antimicrobial susceptibility in Ayder Teaching and Referral Hospital, Mekelle, Ethiopia. BMC Res Notes. 2014;7(1):1–6. doi:10.1186/1756-0500-7-575
   Google Scholar
• Korol E, Johnston K, Waser N, et al. A systematic review of risk factors associated with surgical site infections among surgical patients. PLoS One. 2013;8(12):e83743. doi:10.1371/journal.pone.0083743
   PubMed Web of Science ®Google Scholar
• Purba AK, Setiawan D, Bathoorn E, Postma MJ, Dik JW, Friedrich AW. Prevention of surgical site infections: a systematic review of cost analyses in the use of prophylactic antibiotics. Front Pharmacol. 2018;18(9):776. doi:10.3389/fphar.2018.00776
   Web of Science ®Google Scholar