159
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Factors Associated with 30-Day in-Hospital Mortality Among Patients Admitted with Severe Covid-19 in Mbarara Regional Referral Hospital

ORCID Icon, ORCID Icon, , ORCID Icon, , , , , , , , , , , , & show all
Pages 7157-7164 | Received 21 Jun 2022, Accepted 01 Dec 2022, Published online: 06 Dec 2022

References

  • Figure WHOJGF. Global excess deaths associated with COVID-19: January 2020–December 2021; 2022.
  • Wan Y, Shang J, Graham R, Baric RS, Li FJ. Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus. J Virol. 2020;94(7):e00127–e00120. doi:10.1128/JVI.00127-20
  • Walker PG, Whittaker C, Watson OJ, et al. The impact of COVID-19 and strategies for mitigation and suppression in low-and middle-income countries. Science. 2020;369(6502):413–422.
  • Du R-H, Liang L-R, Yang C-Q, et al. Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study. Eur Respir J. 2020;55(5):2000524. doi:10.1183/13993003.00524-2020
  • World Health Organisation. Uganda situation; 2022. Available from: https://covid19.who.int/region/afro/country/ug. Accessed December 1, 2022.
  • Yanez ND, Weiss NS, Romand J-A, Treggiari MM. COVID-19 mortality risk for older men and women. BMC Public Health. 2020;20(1):1–7.
  • Bongomin F, Fleischer B, Olum R, et al. High mortality during the second wave of the coronavirus disease 2019 (COVID-19) pandemic in Uganda: experience from a national referral COVID-19 treatment unit. Open Forum Infect Dis. 2021;8(11):ofab530. doi:10.1093/ofid/ofab530
  • Alene KA, Elagali A, Barth DD, et al. Spatial codistribution of HIV, tuberculosis and malaria in Ethiopia. BMJ Global Health. 2022;7(2):e007599. doi:10.1136/bmjgh-2021-007599
  • World Health Organisation. HO R&D blueprint novel coronavirus. Contract No.: January 21, 2020; 2020.
  • Ministry of Health. Uganda National guidelines for clinical management of COVID-19. Contract No.: April,2020; 2020.
  • Baguma S, Okot C, Alema NO, et al. Factors associated with mortality among the COVID-19 patients treated at Gulu Regional Referral Hospital: a retrospective study. Front Public Health. 2022;10. doi:10.3389/fpubh.2022.841906
  • Biccard BM, Gopalan PD, Miller M, et al. Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational cohort study. Lancet. 2021;397(10288):1885–1894.
  • Opal SM, Girard TD, Ely EW. The immunopathogenesis of sepsis in elderly patients. Clin Infect Dis. 2005;41(Supplement_7):S504–S512. doi:10.1086/432007
  • Yildiz H, Castanares-Zapatero D, Pierman G, et al. Validation of neutrophil-to-lymphocyte ratio cut-off value associated with high in-hospital mortality in COVID-19 patients. Int J Gen Med. 2021;14:5111. doi:10.2147/IJGM.S326666
  • King AH, Mehkri O, Rajendram P, Wang X, Vachharajani V, Duggal A. A high neutrophil-lymphocyte ratio is associated with increased morbidity and mortality in patients with Coronavirus Disease 2019. Crit Care Explorat. 2021;3(5). doi:10.1097/CCE.0000000000000444
  • Heffernan DS, Monaghan SF, Thakkar RK, Machan JT, Cioffi WG, Ayala A. Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern. Crit Care. 2012;16(1):1–10.
  • Mehraeen E, Karimi A, Barzegary A, et al. Predictors of mortality in patients with COVID-19-a systematic review. Eur J Integrat Med. 2020;40:101226. doi:10.1016/j.eujim.2020.101226
  • Cummings MJ, Baldwin MR, Abrams D, et al. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet. 2020;395(10239):1763–1770. doi:10.1016/S0140-6736(20)31189-2
  • Mansab F, Donnelly H, Kussner A, Neil J, Bhatti S, Goyal DK. Oxygen and mortality in COVID-19 pneumonia: a comparative analysis of supplemental oxygen policies and health outcomes across 26 countries. Front Public Health. 2021;9. doi:10.3389/fpubh.2021.580585