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Infection and Drug Resistance Volume 15, 2022 - Issue
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ORIGINAL RESEARCH

Clinical Course and Risk Factors for Liver Injury of Severe and Critical Patients with COVID-19

Chunjing Du1 Department of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaView further author information
,
Siyuan Yang2 Laboratory of Infectious Diseases Center, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaView further author information
,
Chuansheng Li1 Department of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaView further author information
,
Pan Xiang1 Department of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaView further author information
,
Lin Pu1 Department of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaView further author information
&
Jingyuan Liu1 Department of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
View further author information
Pages 7025-7035 | Received 01 Jul 2022, Accepted 16 Nov 2022, Published online: 02 Dec 2022

References

  • Zhu Y, Liu Y, Jiang H. Geriatric health care during the COVID-19 pandemic: managing the health crisis. Clin Interv Aging. 2022;17:1365–1378. doi:10.2147/CIA.S376519
  • Siso-Almirall A, Kostov B, Sanchez E, et al. Impact of the COVID-19 pandemic on primary health care disease incidence rates: 2017 to 2020. Ann Fam Med. 2022;20(1):63–68. doi:10.1370/afm.2731
  • Li P, Liu Y, Cheng Z, et al. COVID-19-associated liver injury: clinical characteristics, pathophysiological mechanisms and treatment management. Biomed Pharmacother. 2022;154:113568. doi:10.1016/j.biopha.2022.113568
  • Diaz GA, Parsons GT, Gering SK, et al. Myocarditis and pericarditis after vaccination for COVID-19. JAMA. 2021;326(12):1210–1212. doi:10.1001/jama.2021.13443
  • Gupta A, Satapathy AK, Bahinipati P. Delayed catastrophic thrombotic events in post-acute COVID-19. Thromb Res. 2022;220:60–64. doi:10.1016/j.thromres.2022.10.004
  • Jang TY. Liver injury caused by SARS-CoV-2 delta and omicron-variant in Taiwan. J Formos Med Assoc. 2022;121(11):2367–2368. doi:10.1016/j.jfma.2022.06.004
  • Yuan WZ, Fu T. Liver Dysfunction in COVID-19: from Onset to Recovery. Semin Liver Dis. 2022;42(2):151–158. doi:10.1055/s-0042-1745871
  • Luo M, Ballester MP, Soffientini U, et al. SARS-CoV-2 infection and liver involvement. Hepatol Int. 2022;16(4):755–774. doi:10.1007/s12072-022-10364-1
  • Gao YD, Ding M, Dong X, et al. Risk factors for severe and critically ill COVID-19 patients: a review. Allergy. 2021;76(2):428–455. doi:10.1111/all.14657
  • Garrido I, Liberal R, Macedo G. Review article: COVID-19 and liver disease-what we know on 1st May 2020. Aliment Pharmacol Ther. 2020;52(2):267–275. doi:10.1111/apt.15813
  • Ranieri VM, Rubenfeld GD, Thompson BT, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307(23):2526–2533. doi:10.1001/jama.2012.5669
  • Zou L, Ruan F, Huang M, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med. 2020;382(12):1177–1179. doi:10.1056/NEJMc2001737
  • Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–1720. doi:10.1056/NEJMoa2002032
  • Da Silva M, De Lucena AS, Paiva SSL, et al. Cell death mechanisms involved in cell injury caused by SARS-CoV-2. Rev Med Virol. 2022;32(3):e2292. doi:10.1002/rmv.2292
  • McConnell MJ, Kondo R, Kawaguchi N, et al. Covid-19 and liver injury: role of inflammatory endotheliopathy, platelet dysfunction, and thrombosis. Hepatol Commun. 2022;6(2):255–269. doi:10.1002/hep4.1843
  • Zhu DD, Tan XM, Lu LQ, et al. Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injury. World J Gastroenterol. 2021;27(22):2944–2962. doi:10.3748/wjg.v27.i22.2944
  • Mehta P, McAuley DF, Brown M, et al. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020;395(10229):1033–1034. doi:10.1016/S0140-6736(20)30628-0
  • Henry BM. COVID-19, ECMO, and lymphopenia: a word of caution. Lancet Respir Med. 2020;8(4):e24. doi:10.1016/S2213-2600(20)30119-3
  • Stebbing J, Krishnan V, de Bono S, et al. Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients. EMBO Mol Med. 2020;12(8):e12697. doi:10.15252/emmm.202012697
  • Stebbing J, Sanchez NG, Falcone M, et al. JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality. Sci Adv. 2021;7(1). doi:10.1126/sciadv.abe4724
  • Lei HY, Ding YH, Nie K, et al. Potential effects of SARS-CoV-2 on the gastrointestinal tract and liver. Biomed Pharmacother. 2021;133:111064. doi:10.1016/j.biopha.2020.111064
  • Jothimani D, Venugopal R, Abedin MF, et al. COVID-19 and the liver. J Hepatol. 2020;73(5):1231–1240. doi:10.1016/j.jhep.2020.06.006
  • Idalsoaga F, Ayares G, Arab JP, et al. COVID-19 and indirect liver injury: a narrative synthesis of the evidence. J Clin Transl Hepatol. 2021;9(5):760–768. doi:10.14218/JCTH.2020.00140
  • Huang J, Zhang Z, Hao C, et al. Identifying drug-induced liver injury associated with inflammation-drug and drug-drug interactions in pharmacologic treatments for COVID-19 by bioinformatics and system biology analyses: the role of pregnane X receptor. Front Pharmacol. 2022;13:804189. doi:10.3389/fphar.2022.804189

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