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ORIGINAL RESEARCH

Prevalence of Multidrug-Resistant Pathogens Causing Bloodstream Infections in an Intensive Care Unit

ORCID Icon, ORCID Icon, , , , & ORCID Icon show all
Pages 5981-5992 | Received 30 Jul 2022, Accepted 06 Oct 2022, Published online: 17 Oct 2022

References

  • Global action plan on antimicrobial resistance 2016. Available from: https://ahpsr.who.int/publications/i/item/global-action-plan-on-antimicrobial-resistance. Accessed December 28, 2021.
  • Antimicrobial resistance. Available from: https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance. Accessed December 28, 2021.
  • Antimicrobial resistance in the EU/EEA (EARS-Net) – annual epidemiological report for 2019; 2020. Available from: http://www.ecdc.europa.eu. Accessed December 28, 2021.
  • Moolchandani K, Sastry AS, Deepashree R, Sistla S, Harish BN, Mandal J. Antimicrobial resistance surveillance among intensive care units of a Tertiary Care Hospital in Southern India. J Clin Diagn Res. 2017;11(2):DC01–DC07. doi:10.7860/JCDR/2017/23717.9247
  • Licker M, Moldovan R, Hogea E, et al. Multidrug-resistant pathogens in a Romanian intensive care unit – trends and affordable costs. Farmacia. 2017;65(6):929–933.
  • Fraimow HS, Tsigrelis C. Antimicrobial resistance in the intensive care unit: mechanisms, epidemiology, and management of specific resistant pathogens. Crit Care Clin. 2011;27:163–205. doi:10.1016/j.ccc.2010.11.002
  • Zlatian O, Balasoiu AT, Balasoiu M, et al. Antimicrobial resistance in bacterial pathogens among hospitalised patients with severe invasive infections. Exp Ther Med. 2018;16:4499–4510. doi:10.3892/etm.2018.6737
  • Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing, 27th Informational Supplement, M100-S127. Wayne, PA: Clinical and Laboratory Standards Institute (CLSI); 2017.
  • Ghenea AE, Cioboată R, Drocaș AI, et al. Prevalence and antimicrobial resistance of Klebsiella strains isolated from a County Hospital in Romania. Antibiotics. 2021;10:868. doi:10.3390/antibiotics10070868
  • Magiorakos AP, Srinivasan A, Carey RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268–281. doi:10.1111/j.1469-0691.2011.03570.x
  • INSP-CRSPB. Sentinel surveillance methodology for healthcare associated infections and antimicrobial resistance; 2018. Available from: https://www.cnscbt.ro. Accessed October 12, 2022.
  • Golli AL, Nitu FM, Balasoiu M, et al. Antibiotic resistance pattern of bacterial pathogens in elderly patients admitted in the intensive care unit. Rev Chim. 2018;69(12):3433–3438. doi:10.37358/RC.18.12.6764
  • Japoni A, Vazin A, Hamad M, Davarpanah MA, Alborzi A, Rafaatpour N. Multidrug-resistant bacteria isolated from intensive-care-unit patient samples. Braz J Infect Dis. 2009;13(1):82–86. doi:10.1590/S1413-86702009000200009
  • Golli AL, Nitu FM, Balasoiu M, et al. The characterization of antibiotic resistance of bacterial isolates from intensive care unit patient samples in a university affiliated hospital in Romania. Rev Chim. 2019;70(5):1778–1783. doi:10.37358/RC.19.5.7214
  • Golli AL, Nitu FM, Balasoiu M, et al. Bacterial isolates from endotracheal aspirates and their antimicrobial resistance pattern in patients from intensive care unit. Rev Chim. 2019;70(9):3299–3304. doi:10.37358/RC.19.9.7538
  • Licker M, Anghel A, Moldovan R, et al. Microarray technology for the detection of antimicrobial resistance genes present in hospital and community acquired methicillin resistant S.aureus strains. Rev Chim. 2017;68(11):2546–2550. doi:10.37358/RC.17.11.5925
  • Holmbom M, Möller V, Nilsson LE, et al. Low incidence of antibiotic-resistant bacteria in south-east Sweden: an epidemiologic study on 9268 cases of bloodstream infection. PLoS One. 2020;15(3):e0230501. doi:10.1371/journal.pone.0230501
  • Tian L, Zhang Z, Sun Z. Antimicrobial resistance trends in bloodstream infections at a large teaching hospital in China: a 20-year surveillance study (1998–2017). Antimicrob Resist Infect Control. 2019;8:86. doi:10.1186/s13756-019-0545-z
  • Sommerstein R, Damonti L, Marschall J, et al. Distribution of pathogens and antimicrobial resistance in ICU-bloodstream infections during hospitalization: a nationwide surveillance study. Sci Rep. 2021;11(1):16876. doi:10.1038/s41598-021-95873-z
  • Buetti N, Marschall J, Timsit JF, et al; Swiss Centre for Antibiotic Resistance (ANRESIS). Distribution of pathogens and antimicrobial resistance in bacteraemia according to hospitalization duration: a nationwide surveillance study in Switzerland. Clin Microbiol Infect. 2021;27(12):1820–1825. doi:10.1016/j.cmi.2021.04.025
  • Lachhab Z, Frikh M, Maleb A, et al. Bacteraemia in intensive care unit: clinical, bacteriological and prognostic prospective study. Can J Infect Dis Med Microbiol. 2017;2017:4082938. doi:10.1155/2017/4082938
  • Dimopoulos G, Koulenti D, Tabah A, et al. Bloodstream infections in ICU with increased resistance: epidemiology and outcomes. Minerva Anestesiol. 2015;81(4):405–418.
  • Sligl WI, Dragan T, Smith SW. Nosocomial gram-negative bacteremia in intensive care: epidemiology, antimicrobial susceptibilities, and outcomes. Int J Infect Dis. 2015;37:129–134. doi:10.1016/j.ijid.2015.06.024
  • Laxminarayan R, Duse A, Wattal C, et al. Antibiotic resistance - the need for global solutions. Lancet Infect Dis. 2013;13(12):1057–1098. doi:10.1016/S1473-3099(13)70318-9
  • Llor C, Bjerrum L. Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf. 2014;5(6):229–241. doi:10.1177/2042098614554919
  • Radji M, Fauziah S, Aribinuk N. Antibiotic sensitivity pattern of bacterial pathogens in the intensive care unit of Fatmawati Hospital, Indonesia. Asian Pac J Trop Biomed. 2011;1(1):39–42. doi:10.1016/S2221-1691(11)60065-8
  • Balkhy HH, El-Saed A, Alshamrani MM, et al. High burden of resistant gram negative pathogens causing device-associated healthcare infections in a tertiary care setting in Saudi Arabia, 2008–2016. J Glob Antimicrob Resist. 2020;23:26–32. doi:10.1016/j.jgar.2020.07.013
  • Data from the ECDC surveillance atlas - antimicrobial resistance. Available from: www.ecdc.europa.eu/en/antimicrobial-resistance/surveillance-and-disease-data/data-ecdc. Accessed December 28, 2021.
  • ECDC. Point Prevalence Survey of Healthcare-Associated Infections and Antimicrobial Use in European Acute Care Hospitals, 2016–2017. Stockholm: ECDC; 2021.
  • Brolund A, Lagerqvist N, Byfors S, et al; European Antimicrobial Resistance Genes Surveillance Network EURGen-Net Capacity Survey Group. Worsening epidemiological situation of carbapenemase-producing Enterobacteriaceae in Europe, assessment by national experts from 37 countries, July 2018. Euro Surveill. 2019;24(9):1900123. doi:10.2807/1560-7917.ES.2019.24.9.1900123
  • Akter T, Murshed M, Begum T, Nahar K, Duza SS, Shahnaz S. Antimicrobial resistance pattern of bacterial isolates from intensive care unit of a tertiary care hospital in Bangladesh. Bangladesh J Med Microbiol. 2014;8(1):7–11. doi:10.3329/bjmm.v8i1.31052
  • Mutair AA, Alhumaid S, Alawi ZA, et al. Five-year resistance trends in pathogens causing healthcare-associated infections at a multi-hospital healthcare system in Saudi Arabia, 2015–2019. J Glob Antimicrob Resist. 2021;25:142–150. doi:10.1016/j.jgar.2021.03.009
  • Brusselaers N, Vogelaers D, Blot S. The rising problem of antimicrobial resistance in the intensive care unit. Ann Intensive Care. 2011;23(1):47. doi:10.1186/2110-5820-1-47
  • Bhatia A, Kalra J, Kohli S, Kakati B, Kaushik R. Antibiotic resistance pattern in intensive care unit of a tertiary care teaching hospital. Int J Basic Clin Pharmacol. 2018;7(5):906–911. doi:10.18203/2319-2003.ijbcp20181633
  • Gill JS, Arora S, Khanna SP, Kumar KH. Prevalence of multidrug-resistant, extensively drug-resistant, and pandrug-resistant Pseudomonas aeruginosa from a tertiary level intensive care unit. J Glob Infect Dis. 2016;8(4):155–159. doi:10.4103/0974-777X.192962
  • Axente C, Muntean D, Baditoiu L, et al. Beta-lactam resistance mechanisms in pathogens isolated from patients admitted to intensive care unit. Rev Chim. 2017;68(6):1223–1226. doi:10.37358/RC.17.6.5646
  • Stratchounskil LS, Kozlov RS, Rechedko GK, Stetsioukl OU, Chavrikova EI. Antimicrobial resistance patterns among aerobic gram-negative bacilli isolated from patients in intensive care units: results of a multicenter study in Russia. Clin Microbiol Infect. 1998;4:497–507. doi:10.1111/j.1469-0691.1998.tb00404.x
  • Al Bshabshe A, Joseph MRP, Al Hussein A, Haimour W, Hamid ME. Multidrug resistance Acinetobacter species at the intensive care unit, Aseer Central Hospital, Saudi Arabia: a one year analysis. Asian Pac J Trop Med. 2016;9(9):903–908. doi:10.1016/j.apjtm.2016.07.016
  • Carstea D, Streba LA, Glodeanu AD, Carstea AP, Vancu M, Ninulescu AM. The accuracy of combined physical examination and ultrasonography for the detection of abdominal aorta aneurysm. Rom J Morphol Embryol. 2008;49(4):569–572.
  • Zaharie M, Carstea D, Streba CT, et al. Renal dysfunction – a possible marker of severity of heart failure. Rev Chim. 2018;69(6):1435–1440. doi:10.37358/RC.18.6.6341
  • Olteanu M, Niţu M, Golli A. Tuberculosis mesenteric adenopathy and polyserositis. Rom J Morphol Embryol. 2012;53(3 Suppl):835–840.