The Oral Lesion in the COVID-19 Patient: Is It True Oral Manifestation or Not?

References

• Huang CW, Hsieh CH, Lin MR, Huang YC. Clinical features of gingivostomatitis due to primary infection of herpes simplex virus in children. BMC Infect Dis. 2020;20(1):782. doi:10.1186/s12879-020-05509-2
   PubMed Web of Science ®Google Scholar
• Crimi S, Fiorillo L, Bianchi A, et al. Herpes virus, oral clinical signs and QoL: systematic review of recent data. Viruses. 2019;11(5):463. doi:10.3390/v11050463
   PubMed Web of Science ®Google Scholar
• Leung AKC, Barankin B. Herpes labialis: an update. Recent Pat Inflamm Allergy Drug Discov. 2017;11(2). doi:10.2174/1872213X11666171003151717
   Google Scholar
• Lamichhane S, Humagain M, Subba M, Neupane M, Dawadi A. Necrotizing stomatitis in varicella zoster infection. Kathmandu Univ Med J. 2020;18(70):210–213.
   PubMedGoogle Scholar
• Clarkson E, Mashkoor F, Abdulateef S. Oral Viral Infections. Dent Clin North Am. 2017;61(2):351–363. doi:10.1016/j.cden.2016.12.005
   PubMedGoogle Scholar
• Tanaka M, Harada T. Koplik spots in measles. Postgrad Med J. 2019;95(1126):454. doi:10.1136/postgradmedj-2019-136739
   PubMed Web of Science ®Google Scholar
• Jackson CB, Farzan M, Chen B, Choe H. Mechanisms of SARS-CoV-2 entry into cells. Nat Rev Mol Cell Biol. 2022;23(1):3–20. doi:10.1038/s41580-021-00418-x
   PubMed Web of Science ®Google Scholar
• da Rosa Mesquita R, Francelino Silva Junior LC, Santos Santana FM, et al. Clinical manifestations of COVID-19 in the general population: systematic review. Wien Klin Wochenschr. 2021;133(7–8):377–382. doi:10.1007/s00508-020-01760-4
   PubMed Web of Science ®Google Scholar
• Wu YC, Chen CS, Chan YJ. The outbreak of COVID-19. J Chine Med Ass. 2020;83(3):217–220. doi:10.1097/JCMA.0000000000000270
   PubMed Web of Science ®Google Scholar
• Sharma S, Bhardwaj A. COVID tongue. J Indian Soc Periodontol. 2022;26(5):498–500. doi:10.4103/jisp.jisp_437_21
   PubMedGoogle Scholar
• Scotto G, Fazio V, Spirito F, Lo Muzio E, Lo Muzio L. COVID Tongue: suggestive hypothesis or clinical reality? Oral Dis. 2022;28:2618–2619. doi:10.1111/odi.14134
   PubMed Web of Science ®Google Scholar
• Hathway RW. COVID tongue. Br Dent J. 2021;230(3):114. doi:10.1038/s41415-021-2666-z
   PubMed Web of Science ®Google Scholar
• Surboyo MDC, Santosh ABR, Kuntardjo Y, Indriyani I, Ayna VKP, Ernawati DS. COVID tongue: reports, debate, and scope for research. Dental J Advan Stud. 2022;2022:1.
   Google Scholar
• Cuevas-Gonzalez MV, Espinosa-Cristóbal LF, Donohue-Cornejo A, et al. COVID-19 and its manifestations in the oral cavity. Medicine. 2021;100(51):e28327. doi:10.1097/MD.0000000000028327
   PubMed Web of Science ®Google Scholar
• Orilisi G, Mascitti M, Togni L, et al. Oral manifestations of COVID-19 in hospitalized patients: a systematic review. Int J Environ Res Public Health. 2021;18(23):12511. doi:10.3390/ijerph182312511
   PubMed Web of Science ®Google Scholar
• Nijakowski K, Wyzga S, Singh N, Podgórski F, Surdacka A. Oral manifestations in SARS-CoV-2 positive patients: a systematic review. J Clin Med. 2022;11(8):2202. doi:10.3390/jcm11082202
   PubMed Web of Science ®Google Scholar
• Aragoneses J, Suárez A, Algar J, Rodríguez C, López-Valverde N, Aragoneses JM. Oral manifestations of COVID-19: updated systematic review with meta-analysis. Front Med. 2021;8. doi:10.3389/fmed.2021.726753
   Google Scholar
• Nascimento RB, Araujo NS, Silva JC, Xavier FCA. Oral manifestations of multisystemic inflammatory syndrome in children (MIS‐C) and Kawasaki disease associated to COVID‐19: a systematic review. Spec Care Dentist. 2022;42(3):266–280. doi:10.1111/scd.12669
   PubMed Web of Science ®Google Scholar
• Erbaş GS, Botsali A, Erden N, et al. COVID‐19‐related oral mucosa lesions among confirmed SARS‐CoV‐2 patients: a systematic review. Int J Dermatol. 2022;61(1):20–32. doi:10.1111/ijd.15889
   PubMed Web of Science ®Google Scholar
• Xu H, Zhong L, Deng J, et al. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci. 2020;12(1):8. doi:10.1038/s41368-020-0074-x
   PubMed Web of Science ®Google Scholar
• Qi X, Northridge ME, Hu M, Wu B. Oral health conditions and COVID-19: a systematic review and meta-analysis of the current evidence. Aging Health Res. 2022;2(1):100064. doi:10.1016/j.ahr.2022.100064
   PubMedGoogle Scholar
• Di Spirito F, Iandolo A, Amato A, et al. Prevalence, features and degree of association of oral lesions in COVID-19: a systematic review of systematic reviews. Int J Environ Res Public Health. 2022;19(12):7486. doi:10.3390/ijerph19127486
   PubMed Web of Science ®Google Scholar
• Temgoua MN, Endomba FT, Nkeck JR, Kenfack GU, Tochie JN, Essouma M. Coronavirus disease 2019 (COVID-19) as a multi-systemic disease and its impact in low- and middle-income countries (LMICs). SN Compr Clin Med. 2020;2(9):1377–1387. doi:10.1007/s42399-020-00417-7
   PubMedGoogle Scholar
• Doceda MV, Gavriiloglou M, Petit C, Huck O. Oral health implications of SARS-CoV-2/COVID-19: a systematic review. Oral Health Prev Dent. 2022;20(1):207–218. doi:10.3290/j.ohpd.b2960801
   PubMed Web of Science ®Google Scholar
• Uzêda-E-Silva VD, de Sá IB, Martins J, Pedreira N, Vieira VPS, de Silva BHM. Oral lesions associated with COVID-19: a systematic review. Stomatologija. 2021;23(1):3–8.
   PubMedGoogle Scholar
• Bhujel N, Zaheer K, Singh RP. Oral mucosal lesions in patients with COVID-19: a systematic review. Br J Oral Maxillofac Surg. 2021;59(9):1024–1030. doi:10.1016/j.bjoms.2021.06.011
   PubMed Web of Science ®Google Scholar
• Sharma P, Malik S, Wadhwan V, Gotur Palakshappa S, Singh R. Prevalence of oral manifestations in COVID‐19: a systematic review. Rev Med Virol. 2022;32(6). doi:10.1002/rmv.2345
   PubMed Web of Science ®Google Scholar
• Fakhruddin KS, Samaranayake LP, Buranawat B, Ngo H. Oro-facial mucocutaneous manifestations of Coronavirus Disease-2019 (COVID-19): a systematic review. PLoS One. 2022;17(6):e0265531. doi:10.1371/journal.pone.0265531
   PubMed Web of Science ®Google Scholar
• da Santana LAM, Vieira W, Gonçalo RIC, Lima Dos Santos MA, Takeshita WM, Miguita L. Oral mucosa lesions in confirmed and non-vaccinated cases for COVID-19: a systematic review. J Stomatol Oral Maxillofac Surg. 2022;123(5):e241–50. doi:10.1016/j.jormas.2022.05.005
   PubMed Web of Science ®Google Scholar
• Amorim Dos Santos J, Normando AGC, Carvalho da Silva RL, et al. Oral manifestations in patients with COVID-19: a 6-month update. J Dent Res. 2021;2021:002203452110296.
   Google Scholar
• Dar-Odeh N, Bobamuratova DT, Alnazzawi A, et al. Jaw-related complications in COVID-19 patients; a systematic review. CRANIO^®;2022. 1–8. doi:10.1080/08869634.2022.2031438
   Google Scholar
• Samaranayake LP, Fakhruddin KS, Ngo HC, Bandara HM, Leung YY. Orofacial mycoses in coronavirus disease-2019 (COVID-19): a systematic review. Int Dent J. 2022;72(5):607–620. doi:10.1016/j.identj.2022.02.010
   PubMed Web of Science ®Google Scholar
• Di Spirito F, Caggiano M, Di Palo MP, et al. Oral lesions in pediatric subjects: SARS-CoV-2 Infection and COVID-19 Vaccination. Appl Sci. 2022;12(18):8995. doi:10.3390/app12188995
   Google Scholar
• Surboyo MDC, Ernawati DS, Budi HS. Oral mucosal lesions and oral symptoms of the SarS-coV-2 infection. Minerva Dent Oral Sci. 2021;70(4):161–168. doi:10.23736/S2724-6329.21.04493-9
   PubMedGoogle Scholar
• Amorim Dos Santos J, Normando AGC, Carvalho da Silva RL, et al. Oral manifestations in patients with COVID-19: a living systematic review. J Dent Res. 2020;2020:002203452095728.
   Google Scholar
• Reis VP, Bezerra AR, Maia ABP, Marques LC, Conde DC. An integrative review of oral manifestations in patients with COVID‐19: signs directly related to SARS‐CoV‐2 infection or secondary findings? Int J Dermatol. 2022;61(3):278–290. doi:10.1111/ijd.15881
   PubMed Web of Science ®Google Scholar
• Kady DM, Gomaa EA, Abdella WS, Ashraf Hussien R, ElAziz RH A, Khater AGA. Oral manifestations of COVID-19 patients: an online survey of the Egyptian population. Clin Exp Dent Res. 2021;2020:1–9.
   Google Scholar
• Schwab G, Palmieri M, Zerbinati RM, et al. Lack of direct association between oral mucosal lesions and SARS-CoV- 2 in a cohort of patients hospitalised with COVID-19. J Oral Microbiol. 2022;14(1). doi:10.1080/20002297.2022.2047491
   Web of Science ®Google Scholar
• Favia G, Tempesta A, Barile G, et al. Covid-19 symptomatic patients with oral lesions: clinical and histopathological study on 123 cases of the university hospital policlinic of bari with a purpose of a new classification. J Clin Med. 2021;10(4):757. doi:10.3390/jcm10040757
   PubMed Web of Science ®Google Scholar
• Fidan V, Koyuncu H, Akin O. Oral lesions in Covid 19 positive patients. Am J Otolaryngol. 2021;42(3):102905. doi:10.1016/j.amjoto.2021.102905
   PubMed Web of Science ®Google Scholar
• Batista AAF, Ramos KPP, Do Amaral MA, et al. Oral lesions in patients with COVID-19 hospitalized in an intensive care unit: a case-series study. Braz Oral Res. 2022;36:e108. doi:10.1590/1807-3107bor-2022.vol36.0108
   PubMed Web of Science ®Google Scholar
• Subramaniam T, Nikalje M, Jadhav S. Oral manifestations among COVID-19: an observational study of 713 patients. Dent Res J (Isfahan). 2021;18(1):67. doi:10.4103/1735-3327.324026
   PubMedGoogle Scholar
• Soares CD, Souza LL, de Carvalho MGF, et al. Oral manifestations of coronavirus disease 2019 (COVID-19). Am J Surg Pathol. 2022;46(4):528–536. doi:10.1097/PAS.0000000000001825
   PubMed Web of Science ®Google Scholar
• Bianco E, Maddalone M, Ferdeghini C, Mirabelli L, Hari S. Oral Manifestations in Hospitalized COVID Patients. World J Dent. 2022;13(5):434–440. doi:10.5005/jp-journals-10015-2082
   Google Scholar
• Naser AI, Al-Sarraj MN, Deleme ZH. Oral and maxillofacial lesions in COVID 19 infection from Mosul Hospital in Iraq: epidemiological study and approach to classification and treatment. J Oral Res. 2021;10(6):1–14. doi:10.17126/joralres.2021.069
   Google Scholar
• Bardellini E, Bondioni MP, Amadori F, et al. Non-specific oral and cutaneous manifestations of Coronavirus Disease 2019 in children. Med Oral Patol Oral Cir Bucal. 2020;2020:1.
   Google Scholar
• de Paula Eduardo F, Gobbi MF, Bergamin LG, Migliorati CA, Bezinelli LM. Oral care and photobiomodulation protocol for the prevention of traumatic injuries and lip necrosis in critically ill patients with COVID-19: an observational study. Lasers Dent Sci. 2021;5(4):239–245. doi:10.1007/s41547-021-00144-9
   PubMedGoogle Scholar
• Eduardo F, Bezinelli P, Gobbi MF, Bergamin LG, de Carvalho DLC, Corrêa L. Oral lesions and saliva alterations of COVID‐19 patients in an intensive care unit: a retrospective study. Spec Care Dentist. 2022;42(5):494–502. doi:10.1111/scd.12705
   PubMed Web of Science ®Google Scholar
• Santos NMV, Brito DH, Santos TG, et al. Oral manifestations in hospitalized children with COVID-19. Braz Oral Res. 2022;36:e139. doi:10.1590/1807-3107bor-2022.vol36.0139
   PubMed Web of Science ®Google Scholar
• Saraf S, Nalawade T, Mallikarjuna R, Al Kashmiri A. The retrospective pilot study of the prevalence of olfactory dysfunction or loss of smell, loss of taste and oral manifestations among COVID-19 positive health workers in Muscat, Oman. Indian J Otolaryngol Head Neck Surg. 2022;2022:1.
   Google Scholar
• Jimenez-Cauhe J, Ortega-Quijano D, de Perosanz-Lobo D, et al. Enanthem in patients with COVID-19 and skin rash. JAMA Dermatol. 2020;156(10):1134. doi:10.1001/jamadermatol.2020.2550
   PubMed Web of Science ®Google Scholar
• Abubakr N, Salem ZA, Kamel AHM. Oral manifestations in mild-to-moderate cases of covid-19 viral infection in the adult population. Dent Med Probl. 2021;58(1):7–15. doi:10.17219/dmp/130814
   PubMed Web of Science ®Google Scholar
• Katz J, Yue S. Increased odds ratio for COVID-19 in patients with recurrent aphthous stomatitis. J Oral Pathol Med. 2021;50(1):114–117. doi:10.1111/jop.13114
   PubMed Web of Science ®Google Scholar
• Alade O, Folayan MO, Adeniyi A, et al. Differences in oral lesions associated with tobacco smoking, E-Cigarette Use and COVID-19 infection among adolescents and young people in Nigeria. Int J Environ Res Public Health. 2022;19(17):10509. doi:10.3390/ijerph191710509
   PubMed Web of Science ®Google Scholar
• Villarroel-Dorrego M, Chacón L, Rosas R, Barrios V, Pernía Y, Vélez H. Hallazgos bucales en pacientes COVID-19. Actas Dermosifiliogr. 2022;113(2):183–186. doi:10.1016/j.ad.2021.08.007
   PubMed Web of Science ®Google Scholar
• Chawla J, N Y, Bakshi SS, et al. Oral manifestations associated with COVID-19 disease: an observational cross sectional study. J Oral Biol Craniofac Res. 2022;12(2):279–283. doi:10.1016/j.jobcr.2022.03.008
   PubMedGoogle Scholar
• Muthyam A, Reddy M, Kulkarni S, Srilatha A, Sahithi K, Satyanarayana D. Oral manifestations in COVID-19 patients: an observational study. J Family Med Prim Care. 2022;11(3):1000. doi:10.4103/jfmpc.jfmpc_1264_21
   PubMedGoogle Scholar
• Tuter G, Yerebakan M, Celik B, Kara G. Oral manifestations in SARS-CoV-2 infection. Med Oral Patol Oral Cir Bucal. 2022;27(4):e330–9. doi:10.4317/medoral.25259
   PubMed Web of Science ®Google Scholar
• El Tantawi M, Sabbagh HJ, Alkhateeb NA, et al. Oral manifestations in young adults infected with COVID-19 and impact of smoking: a multi-country cross-sectional study. PeerJ. 2022;10:e13555. doi:10.7717/peerj.13555
   PubMed Web of Science ®Google Scholar
• Ganesan A, Kumar S, Kaur A, et al. Oral Manifestations of COVID-19 infection: an analytical cross-sectional study. J Maxillofac Oral Surg. 2022;21:1326–1335. doi:10.1007/s12663-021-01679-x
   PubMedGoogle Scholar
• Binmadi NO, Aljohani S, Alsharif MT, Almazrooa SA, Sindi AM. Oral Manifestations of COVID-19: a cross-sectional study of their prevalence and association with disease severity. J Clin Med. 2022;11(15):4461. doi:10.3390/jcm11154461
   PubMed Web of Science ®Google Scholar
• Elamrousy W, Nassar M, Issa D. Prevalence of oral lesions in COVID-19 Egyptian patients. J Int Soc Prev Community Dent. 2021;11:6.
   PubMed Web of Science ®Google Scholar
• Folayan MO, Zuniga RAA, Ezechi OC, et al. Associations between emotional distress, sleep changes, decreased tooth brushing frequency, self-reported oral Ulcers and SARS-Cov-2 infection during the first wave of the COVID-19 pandemic: a global survey. Int J Environ Res Public Health. 2022;19(18):11550. doi:10.3390/ijerph191811550
   PubMed Web of Science ®Google Scholar
• Hans M, Hans VM, Kahlon N, Sagar M, Pandey AK, Das A. Gustatory dysfunction and oral ulceration in COVID-19 patients: a cross sectional study. Dent Res J. 2022;19:43. doi:10.4103/1735-3327.346401
   PubMedGoogle Scholar
• Özen T, Kahraman FC, Öcal S, Ovalı HF. Skin, mucosa and nail findings in hospitalized pediatric patients with Coronavirus disease-2019 (COVID-19). An Bras Dermatol. 2022;98:208–215. doi:10.1016/j.abd.2022.03.006
   PubMed Web of Science ®Google Scholar
• Bhuyan R, Bhuyan SK, Mohanty JN, et al. A preliminary survey on the oral manifestation of COVID-19 in the First and Second Waves in Bhubaneswar, City of Odisha, India. Nat J Commun Med. 2022;13(5):294–297. doi:10.55489/njcm.130520221617
   PubMedGoogle Scholar
• Natto ZS, Afeef M, Khalil D, et al. Characteristics of oral manifestations in symptomatic non-hospitalized COVID-19 Patients: a cross-sectional study on a sample of the Saudi Population. Int J Gen Med. 2021;14:9547–9553. doi:10.2147/IJGM.S331611
   PubMed Web of Science ®Google Scholar
• Nuno‐Gonzalez A, Martin‐Carrillo P, Magaletsky K, et al. Prevalence of mucocutaneous manifestations in 666 patients with COVID‐19 in a field hospital in Spain: oral and palmoplantar findings. Br J Dermatol. 2021;184(1):184–185. doi:10.1111/bjd.19564
   PubMed Web of Science ®Google Scholar
• Kahraman FC, Çaşkurlu H. Mucosal involvement in a COVID ‐19‐positive patient: a case report. Dermatol Ther. 2020;33:4.
   Web of Science ®Google Scholar
• Eghbali Zarch R, Hosseinzadeh P. COVID ‐19 from the perspective of dentists: a case report and brief review of more than 170 cases. Dermatol Ther. 2021;34(1):1–6. doi:10.1111/dth.14717
   Web of Science ®Google Scholar
• Dominguez‐Santas M, Diaz‐Guimaraens B, Fernandez‐Nieto D, Jimenez‐Cauhe J, Ortega‐Quijano D, Suarez‐Valle A. Minor aphthae associated with SARS‐CoV‐2 infection. Int J Dermatol. 2020;59(8):1022–1023. doi:10.1111/ijd.15004
   PubMed Web of Science ®Google Scholar
• Chaughtai S, Chaughtai Z, Asif A. Conservative treatment with mouthwashes followed by tongue photo biomodulation therapy in Covid-19: a case report. J Med Case Rep. 2022;16(1):367. doi:10.1186/s13256-022-03519-z
   PubMedGoogle Scholar
• Putra BE, Adiarto S, Dewayanti SR, Juzar DA. Viral exanthem with “Spins and needles sensation” on extremities of a COVID-19 patient: a self-reported case from an Indonesian medical frontliner. Int J Infect Dis. 2020;96:355–358. doi:10.1016/j.ijid.2020.05.020
   PubMed Web of Science ®Google Scholar
• Al-Khanati NM, Riad A, Sahloul ME, Klugar M. Aphthous-like stomatitis of COVID-19 patients. Braz J Oral Sci. 2020;19:1–4. doi:10.20396/bjos.v19i0.8661354
   Google Scholar
• Chérif MY, de Filette JMK, André S, Kamgang P, Richert B, Clevenbergh P. Coronavirus disease 2019–related Kawasaki-like disease in an adult: a case report. JAAD Case Rep. 2020;6(8):780–782. doi:10.1016/j.jdcr.2020.06.023
   PubMedGoogle Scholar
• Malih N, Hajinasrollah G, Zare M, Taheri M. Unexpected Presentation of COVID-19 in a 38-year-old male patient: a case report. Case Rep Dermatol. 2020;12(2):124–131. doi:10.1159/000509994
   PubMed Web of Science ®Google Scholar
• Berlingieri G, Alvares CMA, Serrano RV, Palma LF, Campos L. Phototherapies for COVID-19-associated opportunistic oral infections. Photodiagnosis Photodyn Ther. 2022;37:102678. doi:10.1016/j.pdpdt.2021.102678
   PubMed Web of Science ®Google Scholar
• Campeanu AT, Dumea E, Rus M, et al. A rare case of plasmablastic lymphoma in a patient with HIV and SARS-CoV-2 infections. Curr Oncol. 2022;29(3):1537–1543. doi:10.3390/curroncol29030129
   PubMed Web of Science ®Google Scholar
• Saleh W, SHawky E, Halim GA, Ata F. Oral lichen planus after COVID-19, a case report. Ann Med Surg. 2021;72:103051. doi:10.1016/j.amsu.2021.103051
   PubMed Web of Science ®Google Scholar
• Saleh W, Ata F, Elashry MM. Is COVID-19 infection triggering oral herpes zoster? A case report. SAGE Open Med Case Rep. 2021;9:2050313X2110657. doi:10.1177/2050313X211065793
   Web of Science ®Google Scholar
• Corchuelo J, Ulloa FC. Oral manifestations in a patient with a history of asymptomatic COVID-19: case report. Int J Infect Dis. 2020;100:154–157. doi:10.1016/j.ijid.2020.08.071
   PubMed Web of Science ®Google Scholar
• Amorim Dos Santos J, Normando AGC, Carvalho da Silva RL, et al. Oral mucosal lesions in a COVID-19 patient: new signs or secondary manifestations? Int J Infect Dis. 2020;97:326–328. doi:10.1016/j.ijid.2020.06.012
   PubMed Web of Science ®Google Scholar
• Kitakawa D, Oliveira FE, Neves de Castro P, Carvalho LF. Short report - Herpes simplex lesion in the lip semimucosa in a COVID-19 patient. Eur Rev Med Pharmacol Sci. 2020;24(17):9151–9153. doi:10.26355/eurrev_202009_22863
   PubMed Web of Science ®Google Scholar
• Ramires MC, Mattia MB, Tateno RY, Palma LF, Campos L. A combination of phototherapy modalities for extensive lip lesions in a patient with SARS-CoV-2 infection. Photodiagnosis Photodyn Ther. 2021;33(January):102196. doi:10.1016/j.pdpdt.2021.102196
   PubMedGoogle Scholar
• Pauli MA, Pereira LM, Monteiro ML, de Camargo AR, Rabelo GD. Painful palatal lesion in a patient with COVID-19. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021;131(6):620–625. doi:10.1016/j.oooo.2021.03.010
   PubMed Web of Science ®Google Scholar
• De Medeiros VLS, Monteiro-Neto AU, França DDT, Castelo Branco R, de Miranda Coelho ÉO, Takano DM. Pemphigus Vulgaris After COVID-19: a case of induced autoimmunity. SN Compr Clin Med. 2021;3(8):1768–1772. doi:10.1007/s42399-021-00971-8
   PubMedGoogle Scholar
• Nejabi MB, Noor NAS, Raufi N, et al. Tongue ulcer in a patient with COVID-19: a case presentation. BMC Oral Health. 2021;21(1):1–5. doi:10.1186/s12903-021-01635-8
   PubMed Web of Science ®Google Scholar
• Siotos C, Bonett AM, Hansdorfer MA, Siotou K, Kambeyanda RH, Dorafshar AH. Medical device related pressure ulcer of the lip in a patient with COVID-19: case report and review of the literature. J Stomatol Oral Maxillofac Surg. 2020;14(4):337–339.
   Google Scholar
• Martín Carreras-Presas C, Amaro Sánchez J, López-Sánchez AF, Jané-Salas E, Somacarrera Pérez ML. Oral vesiculobullous lesions associated with SARS-CoV-2 infection. Oral Dis. 2021;27(S3):710–712. doi:10.1111/odi.13382
   PubMedGoogle Scholar
• Tapia ROC, Labrador AJP, Guimaraes DM, Valdez LHM. Oral mucosal lesions in patients with SARS‐CoV‐2 infection. Report of four cases. Are they a true sign of COVID‐19 disease? Spec Care Dentist. 2020;3(July):12520.
   Google Scholar
• Riad A, Gomaa E, Hockova B, Klugar M. Oral candidiasis of COVID-19 patients: case report and review of evidence. J Cosmet Dermatol. 2021;20(6):1580–1584. doi:10.1111/jocd.14066
   PubMed Web of Science ®Google Scholar
• Yeom J, Wolk R, Griffin L, Freedman PD, Reich RF. Atypical herpetic ulcerations in COVID-19 positive patients: a report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2022;135:268–271. doi:10.1016/j.oooo.2022.07.015
   PubMed Web of Science ®Google Scholar
• Khodavirdipour A, Asadimanesh M, Masoumi SA. Impact of SARS-CoV-2 genetic blueprints on the oral manifestation of COVID-19: a case report. Glob Med Genet. 2021;08(4):183–185. doi:10.1055/s-0041-1735538
   Google Scholar
• Rafałowicz B, Wagner L, Rafałowicz J. Long COVID oral cavity symptoms based on selected clinical cases. Eur J Dent. 2022;16(02):458–463. doi:10.1055/s-0041-1739445
   PubMedGoogle Scholar
• Manzalawi R, Alhmamey K, Abdelrasoul M. Gingival bleeding associated with COVID‐19 infection. Clin Case Rep. 2021;9(1):294–297. doi:10.1002/ccr3.3519
   PubMed Web of Science ®Google Scholar
• Dalipi ZS, Dragidella F, Dragidella DK. Oral manifestations of exudative erythema multiforme in a patient with COVID-19. Case Rep Dent. 2021;2021:1–8.
   Web of Science ®Google Scholar
• Garcez AS, Delgado MGT, Sperandio M, Dantas Silva FT, de Assis JSR, Suzuki SS. Photodynamic therapy and photobiomodulation on oral lesion in patient with coronavirus disease 2019: a case report. Photobiomodul Photomed Laser Surg. 2021;39(6):386–389. doi:10.1089/photob.2020.4977
   PubMed Web of Science ®Google Scholar
• Palaia G, Pernice E, Pergolini D, et al. Erythema multiforme as early manifestation of COVID-19: a case report. Pathogens. 2022;11(6):654. doi:10.3390/pathogens11060654
   PubMed Web of Science ®Google Scholar
• Al-Akhali MS, Halboub E, Ibraheem W, Khan HK, Hummadi AM. Recurring oral erythema multiforme-like lesions elicited by COVID-19 infection: a case report. Braz Dent Sci. 2022;25(1):e2960. doi:10.4322/bds.2022.e2960
   Google Scholar
• Sircar K, Popli DB, Jha OK, Sircar M, Hasan S. Oral mucosal lesions in moderate-to-severe COVID-19 Disease - An Indian critical care unit experience. J Datta Meghe Inst Med Sci Univ. 2022;17(5):S63–6. doi:10.4103/jdmimsu.jdmimsu_137_22
   Google Scholar
• Mahmoud MS, Taha MS, Mansour OI, et al. Oral mucosal lesions during SARS-CoV-2 infection: a case series and literature review. Egypt J Otolaryngol. 2022;38(1):18. doi:10.1186/s43163-022-00203-3
   Web of Science ®Google Scholar
• Ingale Y, Bommanavar S, Ingale M. Mucormycotic osteomyelitis involving maxilla in SARS-CoV-2 prediabetic patient: a case report 1 2* 3 4. J Krishna Inst Medical Sci Univ. 2022;11(1):105–110.
   Web of Science ®Google Scholar
• Ding X, Ma X, Xu Y, Xu L. HIV-associated mycobacterium Avium Complex, Oral Candida, and SARS-CoV-2 Co-Infection: a rare case report. Infect Drug Resist. 2022;15:7037–7042. doi:10.2147/IDR.S390333
   PubMed Web of Science ®Google Scholar
• Emelyanova N, Isayeva G, Komir I, Shalimova A, Buriakovska O, Vovchenko M. Changes in the oral cavity of a patient after suffering from coronavirus infection COVID-19: a clinical case. Acta Med Mediterr. 2021;37:827–831.
   Web of Science ®Google Scholar
• Talahatu LB, Kaban BE, Ayuningtyas NF, et al. Management of patients with aphthous-like ulcers related to aplastic anaemia in the COVID-19 pandemic era through teledentistry: a case report. Dental J. 2022;55(1):49–55. doi:10.20473/j.djmkg.v55.i1.p49-55
   Google Scholar
• Indu S. Multiple oral ulcerations – an initial manifestation of COVID 19 infection: a personal experience!! J.Oral Maxillofac Pathol. 2020;24(2):227. doi:10.4103/jomfp.JOMFP_324_20
   PubMedGoogle Scholar
• Brandão TB, Gueiros LA, Melo TS, et al. Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;00(00):1–7.
   Google Scholar
• Teixeira IS, Leal FS, Tateno RY, Palma LF, Campos L. Photobiomodulation therapy and antimicrobial photodynamic therapy for orofacial lesions in patients with COVID-19: a case series. Photodiagnosis Photodyn Ther. 2021;34:102281. doi:10.1016/j.pdpdt.2021.102281
   PubMed Web of Science ®Google Scholar
• Riad A, Kassem I, Hockova B, Badrah M, Klugar M. Tongue ulcers associated with SARS‐CoV‐2 infection: a case series. Oral Dis. 2020;2020:13635.
   Google Scholar
• Hocková B, Riad A, Valky J, et al. Oral Complications of ICU Patients with COVID-19: case-series and review of two hundred ten cases. J Clin Med. 2021;10(4):581. doi:10.3390/jcm10040581
   PubMed Web of Science ®Google Scholar
• Sachet P, Rocha BA, Lima FS, et al. Management of orofacial lesions with antimicrobial photodynamic therapy and photobiomodulation protocols in patients with COVID-19: a multicenter case series. Photodiagnosis Photodyn Ther. 2022;38:102743. doi:10.1016/j.pdpdt.2022.102743
   PubMed Web of Science ®Google Scholar
• Riad A, Kassem I, Stanek J, Badrah M, Klugarova J, Klugar M. Aphthous stomatitis in COVID‐19 patients: case‐series and literature review. Dermatol Ther. 2021;34(1):1–4.
   Web of Science ®Google Scholar
• Tomo S, Miyahara GI, Simonato LE. Oral mucositis in a SARS‐CoV‐2‐infected patient: secondary or truly associated condition? Oral Dis. 2020;2020:13570.
   Google Scholar
• Patel J, Woolley J. Necrotizing periodontal disease: oral manifestation of COVID‐19. Oral Dis. 2020;2020:13462.
   Google Scholar
• Ansari R, Gheitani M, Heidari F, Heidari F. Oral cavity lesions as a manifestation of the novel virus (COVID‐19). Oral Dis. 2020;27:13465.
   Web of Science ®Google Scholar
• Demirbaş A, Elmas ÖF, Atasoy M, Türsen Ü, Lotti T.  A case of erythema multiforme major in a patient with COVID 19: the role of corticosteroid treatment. Dermatol Ther. 2020;13:21–23.
   Google Scholar
• Labé P, Ly A, Sin C, et al. Erythema multiforme and Kawasaki disease associated with COVID‐19 infection in children. J Eur Acad Dermatol Venereol. 2020;34. doi:10.1111/jdv.16666
   PubMed Web of Science ®Google Scholar
• Gueiros LA, Neves MCS, Marques CDL. Chikungunya fever and COVID‐19: oral ulcers are a common feature. Oral Dis. 2022;28(S1):1008–1009. doi:10.1111/odi.13717
   PubMedGoogle Scholar
• Hockova B, Riad A, Klugar M, Azar B. Self-case report of oral and skin lesions associated with positivity of COVID-19. J Cosmet Dermatol. 2021;20:1–2.
   Web of Science ®Google Scholar
• McGoldrick DM, Sarai R, Green J. Tongue and floor of mouth swelling: a potential rare manifestation of COVID-19. Br J Oral Maxillofac Surg. 2021;59(4):500–501. doi:10.1016/j.bjoms.2021.03.001
   PubMed Web of Science ®Google Scholar
• Kämmerer T, Walch J, Flaig M, French LE. COVID‐19‐associated herpetic gingivostomatitis. Clin Exp Dermatol. 2021;46(1):174–176. doi:10.1111/ced.14402
   PubMed Web of Science ®Google Scholar
• Chaux-Bodard AG, Deneuve S, Desoutter A. Oral manifestation of Covid-19 as an inaugural symptom? Oral Surg Oral Med Oral Radiol. 2020;26(2):18. doi:10.1051/mbcb/2020011
   Google Scholar
• Cant A, Bhujel N, Harrison M. Oral ulceration as presenting feature of paediatric inflammatory multisystem syndrome associated with COVID-19. Br J Oral Maxillofac Surg. 2020;58(8):1058–1059. doi:10.1016/j.bjoms.2020.06.037
   PubMed Web of Science ®Google Scholar
• Glavina A, Biočina‐Lukenda D, Mravak‐Stipetić M, Markeljević J. Oral symptoms and lesions in SARS‐CoV‐2‐positive patient. Oral Dis. 2020;15:odi.13596.
   Google Scholar
• Gabusi A, Gissi DB, Rossi R, Foschini MP, Montebugnoli L. Persistent lesions in oral cavity after SARS-CoV-2 infection. Oral Dis. 2021;2020:1–2.
   Google Scholar
• Bezerra TM, Feitosa SG, Carneiro DTO, Costa FWG, Pires FR, Pereira KMA. Oral lesions in COVID‐19 infection: is long‐term follow‐up important in the affected patients? Oral Dis. 2020;28:2570–2571
   PubMed Web of Science ®Google Scholar
• Rodríguez MD, Romera AJ, Villarroel M. Oral manifestations associated with COVID‐19. Oral Dis. 2020;28:960.
   PubMed Web of Science ®Google Scholar
• Soares C, Carvalho RA, Carvalho KA, Carvalho MG, Almeida O. Letter to Editor: oral lesions in a patient with Covid-19. Med Oral Patol Oral Cir Bucal. 2020;25(4):e563–4. doi:10.4317/medoral.24044
   PubMed Web of Science ®Google Scholar
• Riad A, Gad A, Hockova B, Klugar M. Oral candidiasis in non‐severe COVID‐19 patients: call for antibiotic stewardship. Oral Surg. 2020;15:465.
   PubMedGoogle Scholar
• Aranda Romo S, Rizo VHT, Noyola Cherpitel DE, et al. Oral lesions as the only signs of recurrent SARS‐CoV‐2 infection. Oral Dis. 2022;28(S2):2614–2615. doi:10.1111/odi.14098
   PubMedGoogle Scholar
• Soares CD, Mosqueda-Taylor A, de Carvalho MGF, de Almeida OP. Oral vesiculobullous lesions as an early sign of COVID-19: immunohistochemical detection of SARS-CoV-2 spike protein. Br J Dermatol. 2021;184(1):e6. doi:10.1111/bjd.19569
   PubMed Web of Science ®Google Scholar
• Aghazadeh N, Homayouni M, Sartori‐Valinotti JC. Oral vesicles and acral erythema: report of a cutaneous manifestation of COVID‐19. Int J Dermatol. 2020;2020:15047.
   Google Scholar
• Dilsiz A, Parlak E, Gül SS. Oral and ocular manifestations in a patient with coronavirus disease-2019: clinical presentation and management. Rev Soc Bras Med Trop. 2022;55:e06992021. doi:10.1590/0037-8682-0699-2021
   PubMed Web of Science ®Google Scholar
• Casu C, Orrù G. Tongue papillitis and volatile sulfur compounds (VSC) values in a COVID-19 patient. Pan Afrn Medl J. 2022;41. doi:10.11604/pamj.2022.41.5.28915
   PubMed Web of Science ®Google Scholar
• Sweet S, Moayedi S, Torres M. Oral aphthous ulcers associated with COVID-19. Vis J Emerg Med. 2022;29:101423. doi:10.1016/j.visj.2022.101423
   PubMedGoogle Scholar
• Muñoz-Corcuera M, Esparza-Gómez G, González-Moles MA, Bascones-Martínez A. Oral ulcers: clinical aspects. A tool for dermatologists. Part I. Acute ulcers. Clin Exp Dermatol. 2009;34(3):289–294. doi:10.1111/j.1365-2230.2009.03220.x
   PubMed Web of Science ®Google Scholar
• Liu D, Yuan X, Gao F, et al. High number and specific comorbidities could impact the immune response in COVID-19 Patients. Front Immunol. 2022;13:899930.
   PubMedGoogle Scholar
• Ergun T, Ergenç İ, Seven S, et al. Drug eruption: a mimicker of Coronavirus disease-2019 rash. Turkderm Turk Arch Dermatol Venereol. 2022;56(1):34–38.
   Web of Science ®Google Scholar
• Mohammad Zadeh N, Mashinchi Asl NS, Forouharnejad K, et al. Mechanism and adverse effects of COVID-19 drugs: a basic review. Int J Physiol Pathophysiol Pharmacol. 2021;13(4):102–109.
   PubMedGoogle Scholar
• Bennardo L, Nisticò SP, Dastoli S, et al. Erythema multiforme and covid‐19: what do we know? Medicina. 2021;57(8):2–7.
   Google Scholar
• Bouabdella S, Benkaraache M, Almheirat Y, Zizi N, Dikhaye S. Erythema multiforme eruption due to SARS-COV 2: case report. Ann Med Surg. 2021;68(June):102591. doi:10.1016/j.amsu.2021.102591
   PubMedGoogle Scholar
• Etaee F, Eftekharian M, Naguib T, Daveluy S. Erythema multiforme inCOVID-19 patients and following COVID-19 vaccination: manifestations, associations and outcomes. J Eur Acad Dermatol Venereol. 2022;36(7):e522–4. doi:10.1111/jdv.18063
   PubMed Web of Science ®Google Scholar
• Zarpellon A, Matuck BF, Dolhnikoff M, et al. Oral lesions and SARS‐CoV‐2: a postmortem study. Oral Dis. 2022;28(S2):2551–2555. doi:10.1111/odi.14047
   PubMedGoogle Scholar