Clinical utility of plecanatide in the treatment of chronic idiopathic constipation

References

• Pinto SanchezMIBercikPEpidemiology and burden of chronic constipationCan J Gastroenterol20112511B15B
   Google Scholar
• CamilleriMFordACMaweGMChronic constipationNat Rev Dis Primers201731709529239347
   PubMed Web of Science ®Google Scholar
• MearinFLacyBEChangLBowel disordersGastroenterology Epub2016218
   Web of Science ®Google Scholar
• DrossmanDAFunctional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IVGastroenterology201615012621279.e1262
   Web of Science ®Google Scholar
• SchmulsonMJDrossmanDAWhat is new in Rome IVJ Neurogastroenterol Moti201723151163
   PubMed Web of Science ®Google Scholar
• ChangLLemboASultanSAmerican Gastroenterological Association Institute Technical Review on the pharmacological management of irritable bowel syndromeGastroenterology201414711491172.e114225224525
   PubMed Web of Science ®Google Scholar
• EswaranSMuirJCheyWDFiber and functional gastrointestinal disordersAm J Gastroenterol201310871872723545709
   PubMed Web of Science ®Google Scholar
• McRorieJWDaggyBPMorelJGDiersingPSMinerPBRobinsonMPsyllium is superior to docusate sodium for treatment of chronic constipationAliment Pharmacol Ther1998124914979663731
   PubMed Web of Science ®Google Scholar
• RaoSSRattanakovitKPatcharatrakulTDiagnosis and management of chronic constipation in adultsNat Rev Gastroenterol Hepatol20161329530527033126
   PubMed Web of Science ®Google Scholar
• FordACSuaresNCEffect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysisGut20116020921821205879
   PubMed Web of Science ®Google Scholar
• DiPalmaJADeRidderPHOrlandoRCKoltsBEClevelandMBA randomized, placebo-controlled, multicenter study of the safety and efficacy of a new polyethylene glycol laxativeAm J Gastroenterol20009544645010685748
   PubMed Web of Science ®Google Scholar
• DipalmaJAClevelandMVMcGowanJHerreraJLA randomized, multicenter, placebo-controlled trial of polyethylene glycol laxative for chronic treatment of chronic constipationAm J Gastroenterol20071021436144117403074
   PubMed Web of Science ®Google Scholar
• ParePFedorakRNSystematic review of stimulant and nonstimulant laxatives for the treatment of functional constipationCan J Gastroenterol Hepatol20142854955725390617
   PubMed Web of Science ®Google Scholar
• Mueller-LissnerSKammMAWaldAMulticenter, 4-week, double-blind, randomized, placebo-controlled trial of sodium picosulfate in patients with chronic constipationAm J Gastroenterol2010105489790320179697
   PubMed Web of Science ®Google Scholar
• KammMAMueller-LissnerSWaldARichterESwallowRGessenerUOral bisacodyl is effective and well-tolerated in patients with chronic constipationClin Gastroenterol Hepatol2011957758321440672
   PubMed Web of Science ®Google Scholar
• KiemanJAHeinickeEASennosides do not kill myenteric neurons in the colon of the rat or mouseNeuroscience1989308378422570374
   PubMed Web of Science ®Google Scholar
• CamilleriMLemboAKatzkaDAOpioids in gastroenterology: treating adverse effects and creating therapeutic benefitsClin Gastroenterol Hepatol2017151338134928529168
   PubMed Web of Science ®Google Scholar
• Coss-AdameERaoSSBrain and gut interactions in irritable bowel syndrome: new paradigms and new understandingsCurr Gastroenterol Rep20141637924595616
   PubMedGoogle Scholar
• ShinACamilleriMKolarGErwinPWestCPMuradMHSystematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipationAliment Pharmacol Ther20143923925324308797
   PubMed Web of Science ®Google Scholar
• MinerPBJrCamilleriMBurtonDPrucalopride induces high-amplitude propagating contractions in the colon of patients with chronic constipation: a randomized studyNeurogastroenterol Motil2016281341134827270968
   PubMed Web of Science ®Google Scholar
• CamilleriMPiessevauxHYiannakouYEfficacy and safety of prucalopride in chronic constipation: an integrated analysis of six randomized, controlled clinical trialsDig Dis Sci2016612357237227056037
   PubMed Web of Science ®Google Scholar
• EmmanuelACoolsMVandeplasscheLKerstensRPrucalopride improves bowel function and colonic transit time in patients with chronic constipation: an integrated analysisAm J Gastroenterol201410988789424732867
   PubMed Web of Science ®Google Scholar
• TackJStanghelliniVDuboisDJosephAVandeplasscheLKerstensREffect of prucalopride on symptoms of chronic constipationNeurogastroenterol Motil201426212724106924
   PubMed Web of Science ®Google Scholar
• LayerPKellerJLoefflerHKreissATegaserod in the treatment of irritable bowel syndrome (IBS) with constipation as the prime symptomTher Clin Risk Manag2007310711818360619
   PubMedGoogle Scholar
• LiFFuTTongWDLubiprostone is effective in the treatment of chronic idiopathic constipation and irritable bowel syndrome: a systematic review and meta-analysis of randomized controlled trialsMayo Clin Proc20169145646827046523
   PubMed Web of Science ®Google Scholar
• CamilleriMBharuchaAEUenoREffect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteersAm J Physiol Gastrointest Liver Physiol2006290G942G94716603730
   PubMed Web of Science ®Google Scholar
• WilsonNScheyRLubiprostone in constipation: clinical evidence and place in therapyTher Adv Chronic Dis20156405025729555
   PubMed Web of Science ®Google Scholar
• JamalMMAdamsABJansenJPWebsterLRA randomized, placebo-controlled trial of lubiprostone for opioid-induced constipation in chronic noncancer painAm J Gastroenterol201511072573225916220
   PubMed Web of Science ®Google Scholar
• CryerBKatzSVallejoRPopescuAUenoRA randomized study of lubiprostone for opioid-induced constipation in patients with chronic noncancer painPain Med2014151825183424716835
   PubMed Web of Science ®Google Scholar
• BarishCFDrossmanDJohansonJFUenoREfficacy and safety of lubiprostone in patients with chronic constipationDig Dis Sci2010551090109720012484
   PubMed Web of Science ®Google Scholar
• Amitiza [package insert]Takeda Pharmaceuticals America IncDeerfield, IL600152017
   Google Scholar
• FieldMIntestinal ion transport and the pathophysiology of diarrheaJ Clin Invest200311193194312671039
   PubMed Web of Science ®Google Scholar
• PfeiferAAszódiASeidlerURuthPHofmannFFässlerRIntestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase IIScience1996274208220868953039
   PubMed Web of Science ®Google Scholar
• VaandragerABBotAGRuthPDifferential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colonGastroenterology200011810811410611159
   PubMed Web of Science ®Google Scholar
• ChaBKimJHHutHcGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring proteinJ Biol Chem2005280166421665015722341
   PubMed Web of Science ®Google Scholar
• JooNSLondonRMKimHDForteLRClarkeLLRegulation of intestinal Cl- and HCO3-secretion by uroguanylinAm J Physiol1998274G633G6449575844
   PubMed Web of Science ®Google Scholar
• VaandragerABStructure and function of the heat-stable enterotoxin receptor/guanylyl cyclase CMol Cell Biochem2002230738311952098
   PubMed Web of Science ®Google Scholar
• FiskerstrandTArshadNHaukanesBIFamilial diarrhea syndrome caused by an activating GUCY2C mutationN Engl J Med20123661586159522436048
   PubMed Web of Science ®Google Scholar
• RomiHCohenILandauDMeconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2CAm J Hum Genet20129089389922521417
   PubMed Web of Science ®Google Scholar
• ForteLRJrUroguanylin and guanylin peptides: pharmacology and experimental therapeuticsPharmacol Ther200410413716215518884
   PubMed Web of Science ®Google Scholar
• WhitakerTLWitteDPScottMCCohenMBUroguanylin and guanylin: distinct but overlapping patterns of messenger RNA expression in mouse intestineGastroenterology1997113100010069287995
   PubMed Web of Science ®Google Scholar
• HamraFKEberSLChinDTCurrieMGForteLRRegulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidityProc Natl Acad Sci U S A199794270527109122260
   PubMed Web of Science ®Google Scholar
• BryantAPBusbyRWBartoliniWPLinaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tractLife Sci20108676076520307554
   PubMed Web of Science ®Google Scholar
• ShailubhaiKComiskeySFossJAPlecanatide, an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract, is safe and well-tolerated in single dosesDig Dis Sci2013582580258623625291
   PubMed Web of Science ®Google Scholar
• MinerPBJrKoltunWDWienerGJA randomized phase III clinical trial of plecanatide, a uroguanylin analog, in patients with chronic idiopathic constipationAm J Gastroenterol201711261362128169285
   PubMed Web of Science ®Google Scholar
• LemboAJSchneierHAShiffSJTwo randomized trials of linaclotide for chronic constipationN Engl J Med201136552753621830967
   PubMed Web of Science ®Google Scholar
• ShahEDKimHMSchoenfeldPEfficacy and tolerability of guanylate cyclase-C agonists for irritable bowel syndrome with constipation and chronic idiopathic constipation: a systematic review and meta-analysisAm J Gastroenterol201811332933829380823
   PubMed Web of Science ®Google Scholar
• BakreMMSoporySVisweswariahSSExpression and regulation of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) in human colonic epithelial cells: role in the induction of cellular refractoriness to the heat-stable enterotoxin peptideJ Cell Biochem20007715916710679826
   PubMed Web of Science ®Google Scholar
• SoporySKaurTVisweswariahSSThe cGMP-binding, cGMP-specific phosphodiesterase (PDE5): intestinal cell expression, regulation and role in fluid secretionCell Signal20041668169215093609
   PubMed Web of Science ®Google Scholar
• SharmanSKIslamBNHouYSildenafil normalizes bowel transit in preclinical models of constipationPLoS One201712e017667328448580
   PubMed Web of Science ®Google Scholar
• RaoSSQuigleyEMShiffSJEffect of linaclotide on severe abdominal symptoms in patients with irritable bowel syndrome with constipationClin Gastroenterol Hepatol20141261662324075889
   PubMed Web of Science ®Google Scholar
• CastroJHarringtonAMHughesPALinaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′,5′-monophosphateGastroenterology2013145613341346e11123958540
   PubMed Web of Science ®Google Scholar
• EutameneHBradesiSLaraucheMGuanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral painNeurogastroenterol Motil201022e312e384
   PubMed Web of Science ®Google Scholar
• FengBKiyatkinMELaJHActivation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferentsJ Neurosci2013339831983923739979
   PubMed Web of Science ®Google Scholar
• ChangWLMasihSThadiAPlecanatide-mediated activation of guanylate cyclase-C suppresses inflammation-induced colorectal carcinogenesis in Apc+/Min-FCCC miceWorld J Gastrointest Pharmacol Ther20178475928217374
   PubMedGoogle Scholar
• IslamBNSharmanSKHouYSildenafil suppresses inflammation-driven colorectal cancer in miceCancer Prev Res (Phila)20171037738828468928
   PubMed Web of Science ®Google Scholar
• ShailubhaiKYuHHKarunanandaaKUroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMPCancer Res2000605151515711016642
   PubMed Web of Science ®Google Scholar
• SharmanSKIslamBNHouYCyclic-GMP-elevating agents suppress polyposis in Apc(Min) mice by targeting the preneoplastic epitheliumCancer Prev Res (Phila)201811819229301746
   PubMed Web of Science ®Google Scholar
• HanXMannEGilbertSLoss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrierPLoS One20116e1613921305056
   PubMed Web of Science ®Google Scholar
• LinJESnookAELiPGUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrityPLoS One20127e3168622384056
   PubMed Web of Science ®Google Scholar
• MannEAHarmel-LawsECohenMBSteinbrecherKAGuanylate cyclase C limits systemic dissemination of a murine enteric pathogenBMC Gastroenterol20131313524004613
   PubMed Web of Science ®Google Scholar
• ShailubhaiKVaseemPKrishna PriyaAPlecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitisWorld J Gastrointest Pharmacol Ther2015621322226558155
   PubMedGoogle Scholar
• WangRKwonIKSinghNType 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epitheliumCell Death Differ20142142743724270408
   PubMed Web of Science ®Google Scholar