Genetic polymorphisms and associated susceptibility to asthma

References

• American Lung AssociationLung Disease Data: 2008New York, NYAmerican Lung Association2008 Available from: http://www.lung.org/assets/documents/publications/lung-disease-data/LDD_2008.pdfAccessed January 7, 2012
   Google Scholar
• MasoliMFabianDHoltSBeasleyRGlobal Initiative for Asthma (GINA) ProgramThe global burden of asthma: executive summary of the GINA Dissemination Committee reportAllergy200459546947815080825
   PubMed Web of Science ®Google Scholar
• PearceNAït-KhaledNBeasleyRISAAC Phase Three Study GroupWorldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC)Thorax200762975876617504817
   PubMed Web of Science ®Google Scholar
• DuffyDLMartinNGBattistuttaDHopperJLMathewsJDGenetics of asthma and hay fever in Australian twinsAm Rev Respir Dis19901426 Pt 1135113582252253
   PubMed Web of Science ®Google Scholar
• HarrisJRMagnusPSamuelsenSOTambsKNo evidence for effects of family environment on asthma. A retrospective study of Norwegian twinsAm J Respir Crit Care Med1997156143499230724
   PubMed Web of Science ®Google Scholar
• KoppelmanGHLosHPostmaDSGenetic and environment in asthma: the answer of twin studiesEur Respir J19991312410836314
   PubMed Web of Science ®Google Scholar
• NieminenMMKaprioJKoskenvuoMA population-based study of bronchial asthma in adult twin pairsChest1991100170752060393
   PubMed Web of Science ®Google Scholar
• BosséYHudsonTJToward a comprehensive set of asthma susceptibility genesAnn Rev Med20075817118416907639
   PubMed Web of Science ®Google Scholar
• BasehoreMJHowardTDLangeLAA comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjectsJ Allergy Clin Immunol20041141808715241348
   PubMed Web of Science ®Google Scholar
• GenuneitJCantelmoJLWeinmayrGISAAC Phase 2 Study GroupA multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2Clin Exp Allergy200939121875188820085599
   PubMed Web of Science ®Google Scholar
• HallerGTorgersonDGOberCThompsonEESequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibilityJ Allergy Clin Immunol2009124612041209e120919910025
   PubMed Web of Science ®Google Scholar
• HowardTDKoppelmanGHXuJGene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthmaAm J Hum Genet200270123023611709756
   PubMed Web of Science ®Google Scholar
• KabeschMSchedelMCarrDIL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthmaJ Allergy Clin Immunol2006117226927416461126
   PubMed Web of Science ®Google Scholar
• Munthe-KaasMCCarlsenKHHalandGT cell-specific T-box transcription factor haplotype is associated with allergic asthma in childrenJ Allergy Clin Immunol20081211515617949803
   PubMed Web of Science ®Google Scholar
• PykäläinenMKinosRValkonenSAssociation analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypesJ Allergy Clin Immunol20051151808715637551
   PubMed Web of Science ®Google Scholar
• RabyBAHwangESVan SteenKT-bet polymorphisms are associated with asthma and airway hyperresponsivenessAm J Respir Crit Care Med20061731647016179640
   PubMed Web of Science ®Google Scholar
• RandolphAGLangeCSilvermanEKThe IL12B gene is associated with asthmaAm J Hum Genet200475470971515322986
   PubMed Web of Science ®Google Scholar
• SuttnerKRosenstielPDepnerMTBX21 gene variants increase childhood asthma risk in combination with HLX1 variantsJ Allergy Clin Immunol20091235106210681068. e1e819362357
   PubMed Web of Science ®Google Scholar
• TantisiraKGHwangESRabyBATBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroidsProc Natl Acad Sci U S A200410152180991810415604153
   PubMed Web of Science ®Google Scholar
• ZhouHHongXJiangSDongHXuXAnalyses of associations between three positionally cloned asthma candidate genes and asthma or asthma-related phenotypes in a Chinese populationBMC Med Genet20091012319951440
   PubMed Web of Science ®Google Scholar
• LiXHowardTDZhengSLGenome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regionsJ Allergy Clin Immunol20101252328335e31120159242
   PubMed Web of Science ®Google Scholar
• PotaczekDPNishiyamaCSanakMSzczeklikAOkumuraKGenetic variability of the high-affinity IgE receptor alpha-subunit (FcepsilonRIalpha)Immunol Res2009451758418726713
   PubMed Web of Science ®Google Scholar
• VladichFDBrazilleSMSternDPeckMLGhittoniRVercelliDIL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammationJ Clin Invest2005115374775415711639
   PubMed Web of Science ®Google Scholar
• WuXLiYChenQAssociation and gene-gene interactions of eight common single-nucleotide polymorphisms with pediatric asthma in middle ChinaJ Asthma201047323824420394509
   PubMed Web of Science ®Google Scholar
• ThompsonSRHumphriesSEInterleukin-18 genetics and inflammatory disease susceptibilityGenes Immun200782919917215860
   PubMed Web of Science ®Google Scholar
• MoffattMFGutIGDemenaisFGABRIEL ConsortiumA large-scale, consortium-based genomewide association study of asthmaN Engl J Med2010363131211122120860503
   PubMed Web of Science ®Google Scholar
• LykourasDSampsonasFKaparianosAKarkouliasKSpiropoulosKRole and pharmacogenomics of TNF-alpha in asthmaMini Rev Med Chem20088993494218691151
   PubMed Web of Science ®Google Scholar
• DuroudierNPTulahASSayersILeukotriene pathway genetics and pharmacogenetics in allergyAllergy200964682383919416143
   PubMed Web of Science ®Google Scholar
• SayersIBartonSRorkeSAllelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthmaThorax200358541742412728163
   PubMed Web of Science ®Google Scholar
• ViaMDe GiacomoACorvolHThe role of LTA4H and ALOX5AP genes in the risk for asthma in LatinosClin Exp Allergy201040458258920067482
   PubMed Web of Science ®Google Scholar
• EderWKlimeckiWYuLALEX-TeamAssociation between exposure to farming, allergies and genetic variation in CARD4/NOD1Allergy20066191117112416918516
   PubMed Web of Science ®Google Scholar
• EderWKlimeckiWYuLALEX Study TeamToll-like receptor 2 as a major gene for asthma in children of European farmersJ Allergy Clin Immunol2004113348248815007351
   PubMed Web of Science ®Google Scholar
• HysiPKabeschMMoffattMFNOD1 variation, immunoglobulin E and asthmaHum Mol Genet200514793594115718249
   PubMed Web of Science ®Google Scholar
• KabeschMCarrDWeilandSKvon MutiusEAssociation between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sampleClin Exp Allergy200434334034515005725
   PubMed Web of Science ®Google Scholar
• KormannMSDepnerMHartlDToll-like receptor heterodimer variants protect from childhood asthmaJ Allergy Clin Immunol20081221869218547625
   PubMed Web of Science ®Google Scholar
• SmitLASirouxVBouzigonEEpidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy (EGEA) Cooperative GroupCD14 and toll-like receptor gene polymorphisms, country living, and asthma in adultsAm J Respir Crit Care Med2009179536336819096003
   PubMed Web of Science ®Google Scholar
• Van EerdeweghPLittleRDDupuisJAssociation of the ADAM33 gene with asthma and bronchial hyperresponsivenessNature2002418689642643012110844
   PubMed Web of Science ®Google Scholar
• SöderhällCMarenholzIKerscherTVariants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitisPLoS Biol200759e24217850181
   PubMed Web of Science ®Google Scholar
• LaitinenTPolviARydmanPCharacterization of a common susceptibility locus for asthma-related traitsScience2004304566830030415073379
   PubMed Web of Science ®Google Scholar
• VendelinJBruceSHolopainenPDownstream target genes of the neuropeptide S-NPSR1 pathwayHum Mol Genet200615192923293516926187
   PubMed Web of Science ®Google Scholar
• PillaiSGGeDZhuGICGN InvestigatorsA genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility lociPLoS Genet200953e100042119300482
   PubMed Web of Science ®Google Scholar
• HimesBEHunninghakeGMBaurleyJWGenome-wide association analysis identifies PDE4D as an asthma-susceptibility geneAm J Hum Genet200984558159319426955
   PubMed Web of Science ®Google Scholar
• SugiuraHIchinoseMNitrative stress in inflammatory lung diseasesNitric Oxide201125213814421440655
   PubMed Web of Science ®Google Scholar
• SmithFJIrvineADTerron-KwiatkowskiALoss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgarisNat Genet200638333734216444271
   PubMed Web of Science ®Google Scholar
• MarenholzINickelRRüschendorfFFilaggrin loss-of-function mutations predispose to phenotypes involved in the atopic marchJ Allergy Clin Immunol2006118486687117030239
   PubMed Web of Science ®Google Scholar
• MorarNCooksonWOHarperJIMoffattMFFilaggrin mutations in children with severe atopic dermatitisJ Invest Dermatol200712771667167217301831
   PubMed Web of Science ®Google Scholar
• PalmerCNIrvineADTerron-KwiatkowskiACommon loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitisNat Genet200638444144616550169
   PubMed Web of Science ®Google Scholar
• PalmerCNIsmailTLeeSPFilaggrin null mutations are associated with increased asthma severity in children and young adultsJ Allergy Clin Immunol20071201646817531295
   PubMed Web of Science ®Google Scholar
• YingSMengQCorriganCJLeeTHLack of filaggrin expression in the human bronchial mucosaJ Allergy Clin Immunol200611861386138817157670
   PubMed Web of Science ®Google Scholar
• HudsonTJSkin barrier function and allergic riskNat Genet200638439940016570058
   PubMed Web of Science ®Google Scholar
• LaingIAde KlerkNHTurnerSWPerth Infant Asthma Follow-up CohortCross-sectional and longitudinal association of the secretoglobin 1A1 gene A38G polymorphism with asthma phenotype in the Perth Infant Asthma Follow-up cohortClin Exp Allergy2009391627119128353
   PubMed Web of Science ®Google Scholar
• LeeJHMooreJHParkSWGenetic interactions model among Eotaxin gene polymorphisms in asthmaJ Hum Genet2008531086787518712274
   PubMed Web of Science ®Google Scholar
• LevyHRabyBALakeSAssociation of defensin beta-1 gene polymorphisms with asthmaJ Allergy Clin Immunol2005115225225815696078
   PubMed Web of Science ®Google Scholar
• MinJWLeeJHParkCSAssociation of eotaxin-2 gene polymorphisms with plasma eotaxin-2 concentrationJ Hum Genet200550311812315744457
   PubMed Web of Science ®Google Scholar
• RabyBAVan SteenKLazarusRCeledónJCSilvermanEKWeissSTEotaxin polymorphisms and serum total IgE levels in children with asthmaJ Allergy Clin Immunol2006117229830516461130
   PubMed Web of Science ®Google Scholar
• SenglerCHeinzmannAJerkicSPClara cell protein 16 (CC16) gene polymorphism influences the degree of airway responsiveness in asthmatic childrenJ Allergy Clin Immunol2003111351551912642831
   PubMed Web of Science ®Google Scholar
• ZhangYGHuangJZhangJRANTES gene polymorphisms and asthma risk: A meta-analysisArch Med Res2010411505820430255
   PubMed Web of Science ®Google Scholar
• OberCHoffjanSAsthma genetics 2006: the long and winding road to gene discoveryGenes Immun2006729510016395390
   PubMed Web of Science ®Google Scholar
• VercelliDDiscovering susceptibility genes for asthma and allergyNat Rev Immunol20088316918218301422
   PubMed Web of Science ®Google Scholar
• ZhangJParéPDSandfordAJRecent advances in asthma geneticsRespir Res20089418197984
   PubMed Web of Science ®Google Scholar
• HalapiEHakonarsonHRecent development in genomic and proteomic research for asthmaCurr Opin Pulm Med2004101223014749602
   PubMed Web of Science ®Google Scholar
• HoffjanSNicolaeDOberCAssociation studies for asthma and atopic diseases: a comprehensive review of the literatureRespir Res200341414748924
   PubMed Web of Science ®Google Scholar
• KabeschMCandidate gene association studies and evidence for gene-by-gene interactionsImmunol Allergy Clin North Am200525468170816257633
   PubMed Web of Science ®Google Scholar
• LiggettSBGenetics of beta 2-adrenergic receptor variants in asthmaClin Exp Allergy199525Suppl 28994 discussion 95–968590354
   PubMed Web of Science ®Google Scholar
• MartinezFDGravesPEBaldiniMSolomonSEricksonRAssociation between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezingJ Clin Invest199710012318431889399966
   PubMed Web of Science ®Google Scholar
• PotterPCVan WykLMartinMLentesKUDowdleEBGenetic polymorphism of the beta-2 adrenergic receptor in atopic and non-atopic subjectsClin Exp Allergy1993231087487710780896
   PubMed Web of Science ®Google Scholar
• NoguchiEYokouchiYZhangJPositional identification of an asthma susceptibility gene on human chromosome 5q33Am J Respir Crit Care Med2005172218318815879417
   PubMed Web of Science ®Google Scholar
• AllenMHeinzmannANoguchiEPositional cloning of a novel gene influencing asthma from chromosome 2q14Nat Genet200335325826314566338
   PubMed Web of Science ®Google Scholar
• NicolaeDCoxNJLesterLAFine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21Am J Hum Genet200576234935715611928
   PubMed Web of Science ®Google Scholar
• ZhangYLeavesNIAndersonGGPositional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthmaNat Gen2003342181186
   PubMed Web of Science ®Google Scholar
• MoffattMFKabeschMLiangLGenetic variants regulating ORMDL3 expression contribute to the risk of childhood asthmaNature2007448715247047317611496
   PubMed Web of Science ®Google Scholar
• BisgaardHBønnelykkeKSleimanPMChromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhoodAm J Respir Crit Care Med2009179317918519029000
   PubMed Web of Science ®Google Scholar
• GalanterJChoudhrySEngCORMDL3 gene is associated with asthma in three ethnically diverse populationsAm J Respir Crit Care Med2008177111194120018310477
   PubMed Web of Science ®Google Scholar
• LeungTFSyHYNgMCAsthma and atopy are associated with chromosome 17q21 markers in Chinese childrenAllergy200964462162819175592
   PubMed Web of Science ®Google Scholar
• SleimanPMAnnaiahKImielinskiMORMDL3 variants associated with asthma susceptibility in North Americans of European ancestryJ Allergy Clin Immunol200812261225122718760456
   PubMed Web of Science ®Google Scholar
• TavendaleRMacgregorDFMukhopadhyaySPalmerCNA polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medicationsJ Allergy Clin Immunol2008121486086318395550
   PubMed Web of Science ®Google Scholar
• FerreiraMAMcRaeAFMedlandSEAssociation between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in AustraliaEur J Hum Genet201119445846421150878
   PubMed Web of Science ®Google Scholar
• RogersAJRabyBALasky-SuJAAssessing the reproducibility of asthma candidate gene associations, using genome-wide dataAm J Respir Crit Care Med2009179121084109019264973
   PubMed Web of Science ®Google Scholar
• DeWanATTricheEWXuXPDE11A associations with asthma: results of a genome-wide association scanJ Allergy Clin Immunol20101264871873e920920776
   PubMed Web of Science ®Google Scholar
• HancockDBRomieuIShiMGenome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican childrenPLoS Genet200958e100062319714205
   PubMed Web of Science ®Google Scholar
• MililiMGauthierLVeranJMatteiMGSchiffCA new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytesImmunology2002106444745512153506
   PubMed Web of Science ®Google Scholar
• SleimanPMFloryJImielinskiMVariants of DENND1B associated with asthma in childrenN Engl J Med20103621364420032318
   PubMed Web of Science ®Google Scholar
• FrankeAMcGovernDPBarrettJCGenome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility lociNat Genet201042121118112521102463
   PubMed Web of Science ®Google Scholar
• MellsGFFloydJAMorleyKIGenome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosisNat Genet201143432933221399635
   PubMed Web of Science ®Google Scholar
• HirotaTTakahashiAKuboMGenome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese populationNat Genet201143989389621804548
   PubMed Web of Science ®Google Scholar
• FerreiraMAMathesonMCDuffyDLAustralian Asthma Genetics ConsortiumIdentification of IL6R and chromosome 11q13.5 as risk loci for asthmaLancet201137897951006101421907864
   PubMed Web of Science ®Google Scholar
• TorgersonDGAmplefordEJChiuGYMexico City Childhood Asthma Study (MCAAS)GillilandFDChildren’s Health Study (CHS) and HARBORS studyBurchardEGGenetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes and Environments (SAGE)MartinezFDChildhood Asthma Research and Education (CARE) NetworkWeissSTChildhood Asthma Management Program (CAMP)WilliamsLKStudy of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)BarnesKCGenetic Research on Asthma in African Diaspora (GRAAD) StudyOberCNicolaeDLMeta-analysis of genome-wide association studies of asthma in ethnically diverse North American populationsNat Genet201143988789221804549
   PubMed Web of Science ®Google Scholar
• OberCTanZSunYEffect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung functionN Engl J Med2008358161682169118403759
   PubMed Web of Science ®Google Scholar
• WeidingerSGiegerCRodriguezEGenome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locusPLoS Genet200848e100016618846228
   PubMed Web of Science ®Google Scholar
• RamasamyACurjuricICoinLJA genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth orderJ Allergy Clin Immunol20111285996100522036096
   PubMed Web of Science ®Google Scholar
• GudbjartssonDFBjornsdottirUSHalapiESequence variants affecting eosinophil numbers associate with asthma and myocardial infarctionNat Genet200941334234719198610
   PubMed Web of Science ®Google Scholar
• WilkJBChenTHGottliebDJA genome-wide association study of pulmonary function measures in the Framingham Heart StudyPLoS Genet200953e100042919300500
   PubMed Web of Science ®Google Scholar
• HancockDBEijgelsheimMWilkJBMeta-analyses of genome-wide association studies identify multiple loci associated with pulmonary functionNat Genet2010421455220010835
   PubMed Web of Science ®Google Scholar
• RepapiESayersIWainLVGenome-wide association study identifies five loci associated with lung functionNat Genet2010421364420010834
   PubMed Web of Science ®Google Scholar
• TorgersonDGCapursoDMathiasRAResequencing candidate genes implicates rare variants in asthma susceptibilityAm J Hum Genet201290227328122325360
   PubMed Web of Science ®Google Scholar
• MartinezFDHolbergCJHalonenMMorganWJWrightALTaussigLMEvidence for Mendelian inheritance of serum IgE levels in Hispanic and non-Hispanic white familiesAm J Hum Genet19945535555658079994
   PubMed Web of Science ®Google Scholar
• MeyersDAPostmaDSPanhuysenCIEvidence for a locus regulating total serum IgE levels mapping to chromosome 5Genomics19942324644707835897
   PubMed Web of Science ®Google Scholar
• NoguchiEShibasakiMArinamiTEvidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese populationAm J Respir Crit Care Med19971565139013939372650
   PubMed Web of Science ®Google Scholar
• PostmaDSBleeckerERAmelungPJGenetic susceptibility to asthma – bronchial hyperresponsiveness coinherited with a major gene for atopyN Engl J Med1995333148949007666875
   PubMed Web of Science ®Google Scholar
• XuJLevittRCPanhuysenCIEvidence for two unlinked loci regulating total serum IgE levelsAm J Hum Genet19955724254307668269
   PubMed Web of Science ®Google Scholar
• BaldiniMLohmanICHalonenMEricksonRPHoltPGMartinezFDA Polymorphism* in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin EAm J Respir Cell Mol Biol199920597698310226067
   PubMed Web of Science ®Google Scholar
• GaoPSMaoXQBaldiniMSerum total IgE levels and CD14 on chromosome 5q31Clin Genet199956216416510517256
   PubMed Web of Science ®Google Scholar
• KoppelmanGHReijmerinkNEColin StineOAssociation of a promoter polymorphism of the CD14 gene and atopyAm J Respir Crit Care Med2001163496596911282774
   PubMed Web of Science ®Google Scholar
• LeungTFTangNLSungYMThe C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese childrenPediatr Allergy Immunol200314425526012911501
   PubMed Web of Science ®Google Scholar
• PachecoKARoseCSSilveiraLJGene-environment interactions influence airways function in laboratory animal workersJ Allergy Clin Immunol2010126223224020579716
   PubMed Web of Science ®Google Scholar
• OberCTsalenkoAParryRCoxNJA second-generation genomewide screen for asthma-susceptibility alleles in a founder populationAm J Hum Genet20006751154116211022011
   PubMed Web of Science ®Google Scholar
• WooJGAssa’adAHeizerABBernsteinJAHersheyGKThe -159 C–>T polymorphism of CD14 is associated with nonatopic asthma and food allergyJ Allergy Clin Immunol2003112243844412897754
   PubMed Web of Science ®Google Scholar
• HeinzmannADietrichHJerkicSPKurzTDeichmannKAPromoter polymorphisms of the CD14 gene are not associated with bronchial asthma in Caucasian childrenEur J Immunogenet200330534534814641542
   PubMedGoogle Scholar
• SenglerCHaiderASommerfeldCGerman Multicenter Allergy Study GroupEvaluation of the CD14 C-159 T polymorphism in the German Multicenter Allergy Study cohortClin Exp Allergy200333216616912580907
   PubMed Web of Science ®Google Scholar
• EderWKlimeckiWYuLAllergy And Endotoxin Alex Study TeamOpposite effects of CD 14/−260 on serum IgE levels in children raised in different environmentsJ Allergy Clin Immunol2005116360160716159630
   PubMed Web of Science ®Google Scholar
• Zambelli-WeinerAEhrlichEStocktonMLEvaluation of the CD14/−260 polymorphism and house dust endotoxin exposure in the Barbados Asthma Genetics StudyJ Allergy Clin Immunol200511561203120915940135
   PubMed Web of Science ®Google Scholar
• NamkungJHLeeJEKimEAn association between IL-9 and IL-9 receptor gene polymorphisms and atopic dermatitis in a Korean populationJ Dermatol Sci2011621162121371865
   PubMed Web of Science ®Google Scholar
• BottemaRWKerkhofMReijmerinkNEGene-gene interaction in regulatory T-cell function in atopy and asthma development in childhoodJ Allergy Clin Immunol20101262338346346. e1e1020599261
   PubMed Web of Science ®Google Scholar
• BottemaRWNolteIMHowardTDInterleukin 13 and interleukin 4 receptor-alpha polymorphisms in rhinitis and asthmaInt Arch Allergy Immunol2010153325926720484924
   PubMed Web of Science ®Google Scholar
• ReijmerinkNEBottemaRWKerkhofMTLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopyAllergy201065219920719968634
   PubMed Web of Science ®Google Scholar
• De LobelLGeurtsPBaeleGCastro-GinerFKogevinasMVan SteenKA screening methodology based on Random Forests to improve the detection of gene-gene interactionsEur J Hum Genet201018101127113220461113
   PubMed Web of Science ®Google Scholar
• ChuJHWeissSTCareyVJRabyBAA graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphismBMC Syst Biol200935519473523
   PubMed Web of Science ®Google Scholar
• HawkinsGAWeissSTBleeckerERClinical consequences of ADRbeta2 polymorphismsPharmacogenomics20089334935818303970
   PubMed Web of Science ®Google Scholar
• MoorePERyckmanKKWilliamsSMPatelNSummarMLShellerJRGenetic variants of GSNOR and ADRB2 influence response to albuterol in African-American children with severe asthmaPediatr Pulmonol200944764965419514054
   PubMed Web of Science ®Google Scholar
• WechslerMEKunselmanSJChinchilliVMNational Heart, Lung and Blood Institute’s Asthma Clinical Research NetworkEffect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trialLancet200937497031754176419932356
   PubMed Web of Science ®Google Scholar
• TaylorDRDrazenJMHerbisonGPYandavaCNHancoxRJTownGIAsthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphismThorax200055976276710950895
   PubMed Web of Science ®Google Scholar
• BleeckerERPos tmaDSLawranceRMMeyer sDAAmbroseHJGoldmanMEffect of ADRB2 polymorphisms on response to longacting beta2-agonist therapy: a pharmacogenetic analysis of two randomised studiesLancet200737096052118212518156033
   PubMed Web of Science ®Google Scholar
• TantisiraKGLasky-SuJHaradaMGenomewide association between GLCCI1 and response to glucocorticoid therapy in asthmaN Engl J Med2011365131173118321991891
   PubMed Web of Science ®Google Scholar
• DrazenJMYandavaCNDubéLPharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatmentNat Genet199922216817010369259
   PubMed Web of Science ®Google Scholar
• LimaJJZhangSGrantAInfluence of leukotriene pathway polymorphisms on response to montelukast in asthmaAm J Respir Crit Care Med2006173437938516293801
   PubMed Web of Science ®Google Scholar
• TantisiraKGLakeSSilvermanESCorticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroidsHum Mol Genet200413131353135915128701
   PubMed Web of Science ®Google Scholar
• HawkinsGALazarusRSmithRSThe glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroidsJ Allergy Clin Immunol2009123613761383e719254810
   PubMed Web of Science ®Google Scholar
• PascualMSuzukiMIsidoro-GarciaMEpigenetic changes in B lymphocytes associated with house dust mite allergic asthmaEpigenetics2011691131113721975512
   PubMed Web of Science ®Google Scholar
• Isidoro-GarcíaMSanzCGarcía-SolaesaVPTGDR gene in asthma: a functional, genetic, and epigenetic studyAllergy201166121553156221883277
   PubMed Web of Science ®Google Scholar
• BalaciLSpadaMCOllaNIRAK-M is involved in the pathogenesis of early-onset persistent asthmaAm J Hum Genet20078061103111417503328
   PubMed Web of Science ®Google Scholar
• WhiteJHChianoMWigglesworthMVestboJPillaiSGGAIN investigatorsIdentification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluationHum Mol Genet200817131890190318344558
   PubMed Web of Science ®Google Scholar
• MathiasRAGrantAVRafaelsNA genome-wide association study on African-ancestry populations for asthmaJ Allergy Clin Immunol20101252336346e419910028
   PubMed Web of Science ®Google Scholar
• NoguchiESakamotoHHirotaTGenome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populationsPLoS Genet201177e100217021814517
   PubMed Web of Science ®Google Scholar
• GranadaMWilkJBTuzovaMA genome-wide association study of plasma total IgE concentrations in the Framingham Heart StudyJ Allergy Clin Immunol20121293840845e2122075330
   PubMed Web of Science ®Google Scholar
• PillaiSGGeDZhuGICGN InvestigatorsA genomewide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility lociPLoS Genet200953e100042119300482
   PubMed Web of Science ®Google Scholar
• ChoMHBoutaouiNKlandermanBJVariants in FAM13A are associated with chronic obstructive pulmonary diseaseNat Genet201042320020220173748
   PubMed Web of Science ®Google Scholar
• ChoMHCastaldiPJWanESICGN Investigators; ECLIPSE Investigators; COPDGene InvestigatorsA genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13Hum Mol Genet201221494795722080838
   PubMed Web of Science ®Google Scholar
• Soler ArtigasMWainLVRepapiEMedical Research Council National Survey of Health and Development (NSHD) Respiratory Study Team, et al; SpiroMeta ConsortiumEffect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung functionAm J Respir Crit Care Med2011184778679521965014
   PubMed Web of Science ®Google Scholar
• ImbodenMBouzigonECurjuricIGenome-wide association study of lung function decline in adults with and without asthmaJ Allergy Clin Immunol201212951218122822424883
   PubMed Web of Science ®Google Scholar