Biomarker Screening and Prognostic Significance Analysis for Renal Cell Carcinoma

References

• Saito K, Arai E, Maekawa K, et al. Lipidomic signatures and associated transcriptomic profiles of clear cell renal cell carcinoma. Sci Rep. 2016;6:28932. doi:10.1038/srep28932
   PubMed Web of Science ®Google Scholar
• Xiao W, Wang X, Wang T, Xing J. Overexpression of BMP1 reflects poor prognosis in clear cell renal cell carcinoma. Cancer Gene Ther. 2020;27(5):330–340. doi:10.1038/s41417-019-0107-9
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(3):145–164.
   PubMed Web of Science ®Google Scholar
• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Hsieh JJ, Purdue MP, Signoretti S, et al. Renal cell carcinoma. Nat Rev Dis Primers. 2017;3:17009. doi:10.1038/nrdp.2017.9
   PubMed Web of Science ®Google Scholar
• Yin H, Zhang H, Wang X, Xu Q. Four methylation-driven genes may be prognostic biomarkers in clear cell renal carcinoma. Clin Transl Med. 2020;10(2):e45. doi:10.1002/ctm2.45
   Web of Science ®Google Scholar
• Yin L, Li W, Xu A, et al. SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway. EBioMedicine. 2020;51:102596. doi:10.1016/j.ebiom.2019.12.005
   PubMed Web of Science ®Google Scholar
• Xiong Z, Xiong W, Xiao W, et al. NNT-induced tumor cell “slimming” reverses the pro-carcinogenesis effect of HIF2a in tumors. Clin Transl Med. 2021;11(1):e264. doi:10.1002/ctm2.264
   PubMed Web of Science ®Google Scholar
• Ravaud A, Motzer RJ, Pandha HS, et al. Adjuvant sunitinib in high-risk renal-cell carcinoma after nephrectomy. N Engl J Med. 2016;375(23):2246–2254. doi:10.1056/NEJMoa1611406
   PubMed Web of Science ®Google Scholar
• Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science. 2011;331(6024):1559–1564. doi:10.1126/science.1203543
   PubMed Web of Science ®Google Scholar
• Campbell S, Uzzo RG, Allaf ME, et al. Renal mass and localized renal cancer: AUA guideline. J Urol. 2017;198(3):520–529. doi:10.1016/j.juro.2017.04.100
   PubMed Web of Science ®Google Scholar
• Chen W, Hill H, Christie A, et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature. 2016;539(7627):112–117. doi:10.1038/nature19796
   PubMed Web of Science ®Google Scholar
• Cancer Genome Atlas Research N. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 2013;499(7456):43–49. doi:10.1038/nature12222
   PubMed Web of Science ®Google Scholar
• Chang WH, Forde D, Lai AG. Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance. Cancer Commun (Lond). 2019;39(1):23. doi:10.1186/s40880-019-0369-5
   PubMed Web of Science ®Google Scholar
• Navas T, Kinders RJ, Lawrence SM, et al. Clinical evolution of epithelial-mesenchymal transition in human carcinomas. Cancer Res. 2020;80(2):304–318.
   PubMed Web of Science ®Google Scholar
• Huang TH, Wu ATH, Cheng TS, et al. In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non-small-cell lung cancer. J Cell Mol Med. 2019;23(12):8184–8195. doi:10.1111/jcmm.14689
   PubMed Web of Science ®Google Scholar
• Qiu H, Li J, Liu Q, Tang M, Wang Y. Apatinib, a novel tyrosine kinase inhibitor, suppresses tumor growth in cervical cancer and synergizes with Paclitaxel. Cell Cycle. 2018;17(10):1235–1244. doi:10.1080/15384101.2018.1471315
   PubMed Web of Science ®Google Scholar
• Li LF, Kao KC, Liu YY, et al. Nintedanib reduces ventilation-augmented bleomycin-induced epithelial-mesenchymal transition and lung fibrosis through suppression of the Src pathway. J Cell Mol Med. 2017;21(11):2937–2949. doi:10.1111/jcmm.13206
   PubMed Web of Science ®Google Scholar
• Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer. 2008;8(8):592–603. doi:10.1038/nrc2442
   PubMed Web of Science ®Google Scholar
• Goldman M, Craft B, Swatloski T, et al. The UCSC cancer genomics browser: update 2015. Nucleic Acids Res. 2015;43(Databaseissue):D812–817. doi:10.1093/nar/gku1073
   PubMed Web of Science ®Google Scholar
• Cheng G, Song Z, Liu Y, et al. Long noncoding RNA SNHG12 indicates the prognosis of prostate cancer and accelerates tumorigenesis via sponging miR-133b. J Cell Physiol. 2020;235(2):1235–1246.
   PubMed Web of Science ®Google Scholar
• Xiao W, Wang X, Wang T, Chen B, Xing J. HAO2 inhibits malignancy of clear cell renal cell carcinoma by promoting lipid catabolic process. J Cell Physiol. 2019;234(12):23005–23016. doi:10.1002/jcp.28861
   PubMed Web of Science ®Google Scholar
• Xiao W, Wang X, Wang T, Xing J. TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival. Cancer Manag Res. 2018;10:5951–5964. doi:10.2147/CMAR.S185270
   PubMed Web of Science ®Google Scholar
• Xiao W, Wang C, Chen K, et al. MiR-765 functions as a tumour suppressor and eliminates lipids in clear cell renal cell carcinoma by downregulating PLP2. EBioMedicine. 2020;51:102622. doi:10.1016/j.ebiom.2019.102622
   PubMed Web of Science ®Google Scholar
• Cai Q, Christie A, Rajaram S, et al. Ontological analyses reveal clinically-significant clear cell renal cell carcinoma subtypes with convergent evolutionary trajectories into an aggressive type. EBioMedicine. 2020;51:102526. doi:10.1016/j.ebiom.2019.10.052
   PubMed Web of Science ®Google Scholar
• Xie QE, Du X, Wang M, et al. Identification of serotonin as a predictive marker for breast cancer patients. Int J Gen Med. 2021;14:1939–1948. doi:10.2147/IJGM.S310591
   PubMed Web of Science ®Google Scholar
• Chen J, Tang H, Li T, et al. Comprehensive analysis of the expression, prognosis, and biological significance of OVOLs in breast cancer. Int J Gen Med. 2021;14:3951–3960. doi:10.2147/IJGM.S326402
   PubMed Web of Science ®Google Scholar
• Gao X, Yang J, Chen Y. Identification of a four immune-related genes signature based on an immunogenomic landscape analysis of clear cell renal cell carcinoma. J Cell Physiol. 2020;235(12):9834–9850. doi:10.1002/jcp.29796
   PubMed Web of Science ®Google Scholar
• Wen YC, Lin YW, Chu CY, et al. Melatonin-triggered post-transcriptional and post-translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma. J Pineal Res. 2020;69(2):e12668. doi:10.1111/jpi.12668
   PubMed Web of Science ®Google Scholar
• Zeng B, Huang Y, Jin S, et al. Development and validation of a mitochondrial metabolism-associated nomogram for prediction of prognosis in clear cell renal cell carcinoma. Clin Transl Med. 2020;10(3):e120.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Udayakumar D, Cai L, et al. Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI. JCI Insight. 2017;2(15):e94278. doi:10.1172/jci.insight.94278
   Web of Science ®Google Scholar
• Qiu B, Ackerman D, Sanchez DJ, et al. HIF2alpha-dependent lipid storage promotes endoplasmic reticulum homeostasis in clear-cell renal cell carcinoma. Cancer Discov. 2015;5(6):652–667. doi:10.1158/2159-8290.CD-14-1507
   PubMed Web of Science ®Google Scholar
• Xiong Z, Xiao W, Bao L, et al. Tumor cell “Slimming” regulates tumor progression through PLCL1/UCP1‐mediated lipid browning. Adv Sci. 2019;6(10):1801862. doi:10.1002/advs.201801862
   Web of Science ®Google Scholar
• Xiao W, Xiong Z, Xiong W, et al. Melatonin/PGC1A/UCP1 promotes tumor slimming and represses tumor progression by initiating autophagy and lipid browning. J Pineal Res. 2019;67(4):e12607. doi:10.1111/jpi.12607
   PubMed Web of Science ®Google Scholar
• Zhu L, Ma N, Wang B, et al. Significant prognostic values of aquaporin mRNA expression in breast cancer. Cancer Manag Res. 2019;11:1503–1515. doi:10.2147/CMAR.S193396
   PubMed Web of Science ®Google Scholar
• Xu WH, Shi SN, Xu Y, et al. Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma. J Transl Med. 2019;17(1):363. doi:10.1186/s12967-019-2113-y
   PubMed Web of Science ®Google Scholar
• Liao S, Chen H, Liu M, et al. Aquaporin 9 inhibits growth and metastasis of hepatocellular carcinoma cells via Wnt/beta-catenin pathway. Aging. 2020;12(2):1527–1544. doi:10.18632/aging.102698
   PubMedGoogle Scholar
• Han M, Xu R, Wang S, et al. Six-transmembrane epithelial antigen of prostate 3 predicts poor prognosis and promotes glioblastoma growth and invasion. Neoplasia. 2018;20(6):543–554. doi:10.1016/j.neo.2018.04.002
   PubMed Web of Science ®Google Scholar
• Zhang M, Lv X, Jiang Y, Li G, Qiao Q. Identification of aberrantly methylated differentially expressed genes in glioblastoma multiforme and their association with patient survival. Exp Ther Med. 2019;18(3):2140–2152.
   PubMed Web of Science ®Google Scholar
• Savci-Heijink CD, Halfwerk H, Koster J, van de Vijver MJ. A novel gene expression signature for bone metastasis in breast carcinomas. Breast Cancer Res Treat. 2016;156(2):249–259. doi:10.1007/s10549-016-3741-z
   PubMed Web of Science ®Google Scholar
• Wang M, Liu B, Li D, et al. Upregulation of IBSP expression predicts poor prognosis in patients with esophageal squamous cell carcinoma. Front Oncol. 2019;9:1117. doi:10.3389/fonc.2019.01117
   PubMed Web of Science ®Google Scholar