The Relationship Between the Expression of CRBN in Peripheral Blood and the Severity and Prognosis of Adult Sepsis

References

• Chiu C, Legrand M. Epidemiology of sepsis and septic shock. Curr Opin Anaesthesiol. 2021;34(2):71–76. doi:10.1097/ACO.0000000000000958
   PubMed Web of Science ®Google Scholar
• Gavelli F, Castello LM, Avanzi GC. Management of sepsis and septic shock in the emergency department. Intern Emerg Med. 2021;16(6):1649–1661. doi:10.1007/s11739-021-02735-7
   PubMed Web of Science ®Google Scholar
• Kim HK, Seol JE, Ahn SW, Jeon S, Park C-S, Han J. Cereblon: promise and challenges for combating human diseases. Pflugers Arch. 2021;473(11):1695–1711. doi:10.1007/s00424-021-02624-0
   PubMed Web of Science ®Google Scholar
• Krasavin M, Adamchik M, Bubyrev A, et al. Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): investigation of their binding mode and antiproliferative effects against myeloma cell lines. Eur J Med Chem. 2023;246:114990. doi:10.1016/j.ejmech.2022.114990
   PubMed Web of Science ®Google Scholar
• Singh H, Agrawal DK. Recent advancements in the discovery of cereblon-based protease-targeted chimeras with potential for therapeutic intervention. Future Med Chem. 2022;14(19):1403–1416. doi:10.4155/fmc-2022-0149
   PubMed Web of Science ®Google Scholar
• Gil M, Kim YK, Kim HY, Pak H-K, Park C-S, Lee KJ. Cereblon deficiency confers resistance against polymicrobial sepsis by the activation of AMP activated protein kinase and heme-oxygenase-1. Biochem Biophys Res Commun. 2018;495(1):976–981. doi:10.1016/j.bbrc.2017.11.098
   PubMed Web of Science ®Google Scholar
• Ayvat P, Diniz G, Gulmez H, et al. Incidence of cereblon protein in intensive care patients: a cross-sectional study. Eur Rev Med Pharmacol Sci. 2023;27(13):6081–6091. doi:10.26355/eurrev_202307_32962
   PubMed Web of Science ®Google Scholar
• Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–810. doi:10.1001/jama.2016.0287
   PubMed Web of Science ®Google Scholar
• Tafelski S, Nachtigall I, Stengel S, Wernecke K, Spies C. Comparison of three models for sepsis patient discrimination according to PIRO: predisposition, infection, response and organ dysfunction. Minerva Anestesiol. 2015;81(3):264–271.
   PubMed Web of Science ®Google Scholar
• Chen Z, Zeng L, Liu G, et al. Construction of autophagy-related gene classifier for early diagnosis, prognosis and predicting immune microenvironment features in sepsis by machine learning algorithms. J Inflamm Res. 2022;15:6165–6186. doi:10.2147/JIR.S386714
   PubMed Web of Science ®Google Scholar
• Rudd KE, Johnson SC, Agesa KM, et al. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the global burden of disease study. Lancet. 2020;395(10219):200–211. doi:10.1016/S0140-6736(19)32989-7
   PubMed Web of Science ®Google Scholar
• Hesterberg RS, Beatty MS, Han Y, et al. Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. Blood. 2020;136(7):857–870. doi:10.1182/blood.2019003257
   PubMed Web of Science ®Google Scholar
• Gregory MA, Manuel-Apolinar L, Sánchez-Garcia S, et al. Soluble intercellular adhesion molecule-1 (sICAM-1) as a biomarker of vascular cognitive impairment in older adults. Dement Geriatr Cogn Disord. 2019;47(4–6):243–253. doi:10.1159/000500068
   PubMed Web of Science ®Google Scholar
• Min Y, Wi SM, Kang J-A, et al. Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6. Cell Death Dis. 2016;7(7):e2313. doi:10.1038/cddis.2016.226
   PubMedGoogle Scholar
• He Y, Sun Y, Peng J. Circ_0114428 regulates sepsis-induced kidney injury by targeting the miR-495-3p/CRBN Axis. Inflammation. 2021;44(4):1464–1477. doi:10.1007/s10753-021-01432-z
   PubMed Web of Science ®Google Scholar
• Yang H, Song Z, Hong D. CRBN knockdown mitigates lipopolysaccharide-induced acute lung injury by suppression of oxidative stress and endoplasmic reticulum (ER) stress associated NF-κB signaling. Bio Pharm. 2020;123:109761. doi:10.1016/j.biopha.2019.109761
   Google Scholar
• Ma H, Liu H, Wu C, Huang L. Diagnostic value of serum heparin binding protein, blood lactic acid combined with hs-CRP in sepsis and its relationship with prognosis. Evid Based Complement Alternat Med. 2021;2021:5023733. doi:10.1155/2021/5023733
   PubMed Web of Science ®Google Scholar
• Cui N, Zhang H, Chen Z, Yu Z. Prognostic significance of PCT and CRP evaluation for adult ICU patients with sepsis and septic shock: retrospective analysis of 59 cases. J Int Med Res. 2019;47(4):1573–1579. doi:10.1177/0300060518822404
   PubMed Web of Science ®Google Scholar
• Sun B, Guo S. miR-486-5p serves as a diagnostic biomarker for sepsis and its predictive value for clinical outcomes. J Inflamm Res. 2021;14:3687–3695. doi:10.2147/JIR.S323433
   PubMed Web of Science ®Google Scholar
• Godinjak A, Iglica A, Rama A, et al. Predictive value of SAPS II and APACHE II scoring systems for patient outcome in a medical intensive care unit. Acta Med Acad. 2016;45(2):97–103. doi:10.5644/ama2006-124.165
   PubMedGoogle Scholar
• Liang P, Yu F. Value of CRP, PCT, and NLR in prediction of severity and prognosis of patients with bloodstream infections and sepsis. Front Surg. 2022;9:857218. doi:10.3389/fsurg.2022.857218
   PubMed Web of Science ®Google Scholar
• Stocker M, van Herk W, El Helou S, et al. C-reactive protein, procalcitonin, and white blood count to rule out neonatal early-onset sepsis within 36 hours: a secondary analysis of the neonatal procalcitonin intervention study. Clin Infect Dis. 2021;73(2):e383–e90. doi:10.1093/cid/ciaa876
   PubMed Web of Science ®Google Scholar