138
Views
40
CrossRef citations to date
0
Altmetric
Original Research

Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner

, , , , , , , & show all
Pages 3547-3559 | Published online: 08 May 2017

References

  • HalasNJNanoscience under glass: the versatile chemistry of silica nanostructuresACS Nano2008217918319206616
  • ParveenSMisraRSahooSKNanoparticles: a boon to drug delivery, therapeutics, diagnostics and imagingNanomedicine2012814716621703993
  • BitarAAhmadNMFessiHElaissariASilica-based nanoparticles for biomedical applicationsDrug Discov Today2012171147115422772028
  • WuJWangCSunJXueYNeurotoxicity of silica nanoparticles: brain localization and dopaminergic neurons damage pathwaysACS Nano201154476448921526751
  • ElderAGeleinRSilvaVTranslocation of inhaled ultrafine manganese oxide particles to the central nervous systemEnviron Health Perspect20061141172117816882521
  • NapierskaDThomassenLCRabolliVSize-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cellsSmall2009584685319288475
  • VallhovHGabrielssonSStrømmeMScheyniusAGarcia-BennettAEMesoporous silica particles induce size dependent effects on human dendritic cellsNano Lett200773576358217975942
  • HeQZhangZGaoFLiYShiJIn vivo biodistribution and urinary excretion of mesoporous silica nanoparticles: effects of particle size and PEGylationSmall2011727128021213393
  • DuanJCYuYBLiYToxic effect of silica nanoparticles on endothelial cells through DNA damage response via Chk1-dependent G2/M checkpointPLoS One20138e6208723620807
  • DuanJCYuYBLiYYuYSunZWCardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish modelBiomaterials2013345853586223663927
  • DuanJCYuYBYuYSilica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesisPart Fibre Toxicol201411505825266717
  • DuanJCYuYBYuYSilica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathwayInt J Nanomedicine201495131514125395850
  • ArianoPZamburlinPGilardinoAInteraction of spherical silica nanoparticles with neuronal cells: size-dependent toxicity and perturbation of calcium homeostasisSmall2011776677421302356
  • BiedlerJLHelsonLSpenglerBAMorphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous cultureCancer Res197333264326524748425
  • ParodiAHaddixSGTaghipourNBromelain surface modification increases the diffusion of silica nanoparticles in the tumor extracellular matrixACS Nano201489874988325119793
  • OrlandoAReFSesanaSEffect of nanoparticles binding β-amyloid peptide on nitric oxide production by cultured endothelial cells and macrophagesInt J Nanomedicine201381335134723717039
  • ReFCambianicaISesanaSFunctionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptideJ Biotechnol2010156341346
  • De KimpeLBennisAZwartRvan HaastertESHoozemansJJScheperWDisturbed Ca2+ homeostasis increases glutaminyl cyclase expression; connecting two early pathogenic events in Alzheimer’s disease in vitroPLoS One20127e4467422970285
  • BanaLMinnitiSSalvatiELiposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood-brain-barrier: implications for therapy of Alzheimer diseaseNanomedicine2014101583159024333591
  • HevelJMMarlettaMANitric-oxide synthase assaysMethods Enzymol19942332502587516999
  • ShiMChengLZhangZLiuZMaoXFerroferric oxide nanoparticles induce prosurvival autophagy in human blood cells by modulating the beclin 1/Bcl-2/VPS34 complexInt J Nanomedicine20141020721625565814
  • GulloFMaffezzoliADossiEWankeEShort latency cross-and autocorrelation identify clusters of interacting neurons recorded from multi-electrode arraysJ Neurosci Methods200918118619819447135
  • WagenaarDAPineJPotterSMAn extremely rich repertoire of bursting patterns during the development of cortical culturesBMC Neurosci200671116464257
  • GulloFMazzettiSMaffezzoliAOrchestration of “presto” and “largo” synchrony in up-down activity of cortical networksFront Neural Circuits201041120461235
  • BecchettiAGulloFBrunoGDossiEWankeEExact distinction of excitatory and inhibitory neurons in neural networks: a study with GFP-GAD67 neurons optically and electrophysiologically recognized on multielectrode arraysFront Neural Circuits201266322973197
  • DudaORHartPEStorkDGPattern ClassificationNew YorkWiley2000
  • HamMIBettencourtLMMcDanielFDGrossGWSpontaneous coordinated activity in cultured networks: analysis of multiple ignition sites, primary circuits and phase delay distributionJ Comput Neurosci20082434635718066657
  • BaddeleyRAbbotLFBoothMCResponses of neurons in primary and inferior temporal visual cortices to natural scenesProc Biol Sci1997264177517839447735
  • RosenholmJMSahlgrenCLindénMMultifunctional mesoporous silica nanoparticles for combined therapeutic, diagnostic and targeted action in cancer treatmentCurr Drug Targets2011211661186
  • MontaltiMProdiLRampazzoEZaccheroniNDye-doped silica nanoparticles as luminescent organized systems for nanomedicineChem Soc Rev2014434243426824643354
  • SimkóMMattssonMORisks from accidental exposures to engineered nanoparticles and neurological health effects: a critical reviewPart Fibre Toxicol201074221176150
  • KimIYJoachimEChoiHKimKToxicity of silica nanoparticles depends on size, dose, and cell typeNanomedicine2015111407141625819884
  • NowakJSMehnDNativoPSilica nanoparticle uptake induces survival mechanism in A549 cells by the activation of autophagy but not apoptosisToxicol Lett2014224849224140553
  • ZhangZZhouLZhouYMitophagy induced by nanoparticle-peptide conjugates enabling an alternative intracellular trafficking routeBiomaterials201565566526142776
  • ZhangXShenWGurunathanSSilver nanoparticle-mediated cellular responses in various cell lines: an in vitro modelInt J Mol Sci20161716031629
  • LiJMaoHKawazoeNChenGInsight into the interactions between nanoparticles and cellsBiomater Sci2017517318927935611