References
- Vander HeidenMGCantleyLCThompsonCBUnderstanding the Warburg effect: the metabolic requirements of cell proliferationScience200932459301029103319460998
- KimJWDangCVCancer’s molecular sweet tooth and the Warburg effectCancer Res200666188927893016982728
- ChenZLuWGarcia-PrietoCHuangPThe Warburg effect and its cancer therapeutic implicationsJ Bioenerg Biomembr200739326727417551814
- GatenbyRAGilliesRJGlycolysis in cancer: a potential target for therapyInt J Biochem Cell Biol2007397–81358136617499003
- KroemerGPouyssegurJTumor cell metabolism: cancer’s Achilles’ heelCancer Cell200813647248218538731
- DeBerardinisRJLumJJHatzivassiliouGThompsonCBThe biology of cancer: metabolic reprogramming fuels cell growth and proliferationCell Metab200871112018177721
- CairnsRAHarrisISMakTWRegulation of cancer cell metabolismNat Rev Cancer2011112859521258394
- LinXZhangFBradburyCM2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolismCancer Res200363123413341712810678
- PelicanoHMartinDSXuRHHuangPGlycolysis inhibition for anticancer treatmentOncogene200625344633464616892078
- ZhaoYButlerEBTanMTargeting cellular metabolism to improve cancer therapeuticsCell Death Dis20134e53223470539
- ZhengJEnergy metabolism of cancer: glycolysis versus oxidative phosphorylationOncol Lett2012461151115723226794
- RohlenaJDongLFRalphSJNeuzilJAnticancer drugs targeting the mitochondrial electron transport chainAntioxid Redox Signal201115122951297421777145
- dos SantosGAAbreu e LimaRSPestanaCR(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivoLeukemia201226345146021869839
- KluckovaKBezawork-GeletaARohlenaJDongLNeuzilJMitochondrial complex II, a novel target for anti-cancer agentsBiochim Biophys Acta20131827555256423142170
- ProchazkaLDongLFValisKAlpha-Tocopheryl succinate causes mitochondrial permeabilization by preferential formation of Bak channelsApoptosis201015778279420217235
- ValisKProchazkaLBouraEHippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent mannerCancer Res201171394695421245099
- KruspigBNilchianABejaranoIOrreniusSZhivotovskyBGogvadzeVTargeting mitochondria by α-tocopheryl succinate kills neuroblastoma cells irrespective of MycN oncogene expressionCell Mol Life Sci201269122091209922286068
- NeuzilJMassaHHepatic processing determines dual activity of alpha-tocopheryl succinate: a novel paradigm for a shift in biological activity due to pro-vitamin-to-vitamin conversionBiochem Biophys Res Commun200532741024102715652498
- Palao-SuayRRodrigáñezLAguilarMRMitochondrially targeted nanoparticles based on α-TOS for the selective cancer treatmentMacromol Biosci201616339541126632009
- KoudelkaSTuranek KnotigovaPMasekJLiposomal delivery systems for anti-cancer analogues of vitamin EJ Control Release2015207596925861728
- ChenMCSonajeKChenKJSungHWA review of the prospects for polymeric nanoparticle platforms in oral insulin deliveryBiomaterials201132369826983821925726
- ParkSKangSChenXTumor suppression via paclitaxel-loaded drug carriers that target inflammation marker upregulated in tumor vasculature and macrophagesBiomaterials201334259860523099063
- ZengXTaoWMeiLHuangLTanCFengSSCholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancerBiomaterials201334256058606723694904
- ZhangHLiuGZengXFabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cellsInt J Nanomedicine2015102461247325848264
- LowPSHenneWADoorneweerdDDDiscovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseasesAcc Chem Res200841112012917655275
- LiKLiuHGaoWMulberry-like dual-drug complicated nanocarriers assembled with apogossypolone amphiphilic starch micelles and doxorubicin hyaluronic acid nanoparticles for tumor combination and targeted therapyBiomaterials20153913114425477180
- MengHChenJYMiLConjugates of folic acids with BSA-coated quantum dots for cancer cell targeting and imaging by single-photon and two-photon excitationJ Biol Inorg Chem201116111712320890718
- AftRLZhangFWGiusDEvaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell deathBr J Cancer200287780581212232767
- DongLFJamesonVJTillyDMitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapyFree Radic Biol Med201150111546155521402148
- MüllerCSchubigerPASchibliRIn vitro and in vivo targeting of different folate receptor-positive cancer cell lines with a novel 99mTc-radiofolate tracerEur J Nucl Med Mol Imaging200633101162117016721570
- GoldbergLIsraeliRKloogYFTS and 2-DG induce pancreatic cancer cell death and tumor shrinkage in miceCell Death Dis20123e28422419113
- CheongJHParkESLiangJDual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer modelsMol Cancer Ther201110122350236221992792
- ZhangXPengXYuWAlpha-tocopheryl succinate enhances doxorubicin-induced apoptosis in human gastric cancer cells via promotion of doxorubicin influx and suppression of doxorubicin effluxCancer Lett2011307217418121536373
- LiuHLiKLanLDouble-layered hyaluronic acid/stearic acid-modified polyethyleneimine nanoparticles encapsulating (-)-gossypol: a nanocarrier for chiral anticancer drugsJ Mater Chem B Mater Biol Med20142325238524826893903
- DongLFFreemanRLiuJSuppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex IIClin Cancer Res20091551593160019223492