1,208
Views
265
CrossRef citations to date
0
Altmetric
Review

Antimicrobial hydrogels: promising materials for medical application

, , , , , & show all
Pages 2217-2263 | Published online: 12 Apr 2018

References

  • StonePWPogorzelska-MaziarzMHerzigCTState of infection prevention in US hospitals enrolled in the National Health and Safety NetworkAm J Infect Control2014422949924485365
  • NgVWChanJMSardonHAntimicrobial hydrogels: a new weapon in the arsenal against multidrug-resistant infectionsAdv Drug Deliv Rev201478466225450263
  • Global Burden of Disease Study 2013 CollaboratorsGlobal, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013Lancet2015386999574380026063472
  • García-BarrasaJLópez-de-LuzuriagaJMMongeMSilver nanoparticles: synthesis through chemical methods in solution and biomedical applicationsCent Eur J Chem201091719
  • AokiWKurodaKUedaMNext generation of antimicrobial peptides as molecular targeted medicinesJ Biosci Bioeng2012114436537022658802
  • MalmstenMAntimicrobial and antiviral hydrogelsSoft Matter20117198725
  • MartinezJLFajardoAGarmendiaLA global view of antibiotic resistanceFEMS Microbiol Rev2009331446519054120
  • MartinezJLRojoFMetabolic regulation of antibiotic resistanceFEMS Microbiol Rev201135576878921645016
  • Mazer-AmirshahiMPourmandAMayLNewly approved antibiotics and antibiotics reserved for resistant infections: implications for emergency medicineAm J Emerg Med201735115415828029487
  • RameshSGovenderTKrugerHGde la TorreBGAlbericioFShort AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agentsJ Pept Sci201622743845127352996
  • ScorciapinoMASerraIManzoGRinaldiACAntimicrobial dendrimeric peptides: structure, activity and new therapeutic applicationsInt J Mol Sci2017183E54228273806
  • KangHKKimCSeoCHParkYThe therapeutic applications of antimicrobial peptides (AMPs): a patent reviewJ Microbiol201755111228035594
  • DasguptaAMondalJHDasDPeptide hydrogelsRSC Adv20133249117
  • MitraRNShomeAPaulPDasPKAntimicrobial activity, biocompatibility and hydrogelation ability of dipeptide-based amphiphilesOrg Biomol Chem2009719410219081951
  • Muñoz-BonillaAFernández-GarcíaMPolymeric materials with antimicrobial activityProg Polym Sci2012372281339
  • KongMChenXGXingKParkHJAntimicrobial properties of chitosan and mode of action: a state of the art reviewInt J Food Microbiol20101441516320951455
  • JamilBImranMFactors pivotal for designing of nanoantimicrobials: an expositionCrit Rev Microbiol2018441799428421881
  • CavalieriFTortoraMStringaroAColoneMBaldassarriLNanomedicines for antimicrobial interventionsJ Hosp Infect201488418319025447199
  • MohamedRRSeoudiRSSabaaMWSynthesis and characterization of antibacterial semi-interpenetrating carboxymethyl chitosan/poly (acrylonitrile) hydrogelsCellulose2012193947958
  • HamidiMAzadiARafieiPHydrogel nanoparticles in drug deliveryAdv Drug Deliv Rev200860151638164918840488
  • ZhangSErmannJSucciMDAn inflammation-targeting hydrogel for local drug delivery in inflammatory bowel diseaseSci Transl Med20157300300ra128
  • NoimarkSDunnillCWWilsonMParkinIPThe role of surfaces in catheter-associated infectionsChem Soc Rev200938123435344820449061
  • HetrickEMSchoenfischMHReducing implant-related infections: active release strategiesChem Soc Rev200635978078916936926
  • SheaLDWoodruffTKShikanovABioengineering the ovarian follicle microenvironmentAnnu Rev Biomed Eng201416295224849592
  • GhobrilCGrinstaffMWThe chemistry and engineering of polymeric hydrogel adhesives for wound closure: a tutorialChem Soc Rev20154471820183525649260
  • SahinerNSagbasSSahinerMSilanCAktasNTurkMBiocompatible and biodegradable poly(Tannic Acid) hydrogel with antimicrobial and antioxidant propertiesInt J Biol Macromol20168215015926526171
  • TsaoCTChangCHLinYYAntibacterial activity and biocompatibility of a chitosan-gamma-poly(glutamic acid) polyelectrolyte complex hydrogelCarbohydr Res2010345121774178020598293
  • HemegHANanomaterials for alternative antibacterial therapyInt J Nanomedicine2017128211822529184409
  • SahinerNSoft and flexible hydrogel templates of different sizes and various functionalities for metal nanoparticle preparation and their use in catalysisProg Polym Sci201338913291356
  • HuRLiGJiangYSilver–zwitterion organic–inorganic nanocomposite with antimicrobial and antiadhesive capabilitiesLangmuir201329113773377923425314
  • PelgriftRYFriedmanAJNanotechnology as a therapeutic tool to combat microbial resistanceAdv Drug Deliv Rev20136513–141803181523892192
  • SkladanowskiMGolinskaPEvaluation of cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticlesMed Microbiol Immunol2016205660361327620485
  • BlecherKNasirAFriedmanAThe growing role of nanotechnology in combating infectious diseaseVirulence20112539540121921677
  • LaraHHAyala-NúñezNVPadillaCRBactericidal effect of silver nanoparticles against multidrug-resistant bacteriaWorld J Microbiol Biotechnol2010264615621
  • HuhAJKwonYJ“Nanoantibiotics”: a new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant eraJ Control Release2011156212814521763369
  • HindiKMDittoAJPanznerMJThe antimicrobial efficacy of sustained release silver-carbene complex-loaded L-tyrosine polyphosphate nanoparticles: characterization, in vitro and in vivo studiesBiomaterials200930223771377919395021
  • DallasPSharmaVKZborilRSilver polymeric nanocomposites as advanced antimicrobial agents: classification, synthetic paths, applications, and perspectivesAdv Colloid Interface Sci20111661–211913521683320
  • PatilMPKimGDEco-friendly approach for nanoparticles synthesis and mechanism behind antibacterial activity of silver and anticancer activity of gold nanoparticlesAppl Microbiol Biotechnol20171011799227915376
  • IvaskAElbadawyAKaweeteerawatCToxicity mechanisms in Escherichia coli vary for silver nanoparticles and differ from ionic silverACS Nano20148137438624341736
  • TagliettiADiaz FernandezYAAmatoEAntibacterial activity of glutathione-coated silver nanoparticles against Gram Positive and Gram Negative bacteriaLangmuir201228218140814822546237
  • GuoLYuanWLuZLiCMPolymer/nanosilver composite coatings for antibacterial applicationsColloids Surf A Phys Eng Aspects20134396983
  • KnetschMLWKooleLHNew strategies in the development of antimicrobial coatings: the example of increasing usage of silver and silver nanoparticlesPolymers201131340366
  • JovanovićŽStojkovskaJObradovićBMišković-StankovićVAlginate hydrogel microbeads incorporated with Ag nanoparticles obtained by electrochemical methodMater Chem Phys20121331182189
  • StojkovskaJKostićDJovanovićŽVukašinović-SekulićMMišković- StankovićVObradovićBA comprehensive approach to in vitro functional evaluation of Ag/alginate nanocomposite hydrogelsCarbohydr Polym201411130531425037356
  • ObradovicBStojkovskaJJovanovicZMiskovic-StankovicVNovel alginate based nanocomposite hydrogels with incorporated silver nanoparticlesJ Mater Sci Mat Med201223199107
  • GhasemzadehHGhanaatFAntimicrobial alginate/PVA silver nanocomposite hydrogel, synthesis and characterizationJ Polym Res2014213355
  • Madhusudana RaoKKrishna RaoKSVRamanjaneyuluGChowdoji RaoKSubhaMCSHaC-SBiodegradable sodium alginate-based semi-interpenetrating polymer network hydrogels for antibacterial applicationJ Biomed Mater Res A201310293196320624151188
  • Murali MohanYVimalaKThomasVControlling of silver nanoparticles structure by hydrogel networksJ Colloid Interface Sci20103421738219883919
  • NeibertKGopishettyVGrigoryevAWound-healing with mechanically robust and biodegradable hydrogel fibers loaded with silver nanoparticlesAdv Healthc Mater20121562163023184797
  • MurthyPSMurali MohanYVaraprasadKSreedharBMohana RajuKFirst successful design of semi-IPN hydrogel-silver nanocomposites: a facile approach for antibacterial applicationJ Colloid Interface Sci2008318221722418005980
  • ChangHWLinYSTsaiYDTsaiMLEffects of chitosan characteristics on the physicochemical properties, antibacterial activity, and cytotoxicity of chitosan/2-glycerophosphate/nanosilver hydrogelsJ Appl Polym Sci20131271169176
  • TangHLuALiLZhouWXieZZhangLHighly antibacterial materials constructed from silver molybdate nanoparticles immobilized in chitin matrixChem Eng J2013234124131
  • JayaramuduTRaghavendraGMVaraprasadKSadikuRRamamKRajuKMIota-Carrageenan-based biodegradable Ag0 nanocomposite hydrogels for the inactivation of bacteriaCarbohydr Polym201395118819423618258
  • JubyKADwivediCKumarMKotaSMisraHSBajajPNSilver nanoparticle-loaded PVA/gum acacia hydrogel: synthesis, characterization and antibacterial studyCarbohydr Polym201289390691324750879
  • HebeishAHashemMEl-HadyMMSharafSDevelopment of CMC hydrogels loaded with silver nanoparticles for medical applicationsCarbohydr Polym201392140741323218313
  • VimalaKSamba SivuduKMurali MohanYSreedharBMohana RajuKControlled silver nanoparticles synthesis in semi-hydrogel networks of poly(acrylamide) and carbohydrates: a rational methodology for antibacterial applicationCarbohydr Polym2009753463471
  • ReddyPRVaraprasadKSadikuRDevelopment of gelatin based inorganic nanocomposite hydrogels for inactivation of bacteriaJ Inorg Organometal Polym Mater201323510541060
  • El-SherifHEl-MasryMKansohAHydrogels as template nanoreactors for silver nanoparticles formation and their antimicrobial activitiesMacromol Res2011191111571165
  • ParkSMurthyPSKParkSMohanYMKohW-GPreparation of silver nanoparticle-containing semi-interpenetrating network hydrogels composed of pluronic and poly(acrylamide) with antibacterial propertyJ Ind Eng Chem2011172293297
  • VaraprasadKMohanYMRavindraSHydrogel-silver nanoparticle composites: a new generation of antimicrobialsJ Appl Polym Sci2010115211991207
  • EidMArabyEBactericidal effect of poly(acrylamide/itaconic acid)-silver nanoparticles synthesized by gamma irradiation against Pseudomonas aeruginosaAppl Biochem Biotechnol2013171246948723857355
  • Abdel-HalimESAl-DeyabSSAntimicrobial activity of silver/starch/polyacrylamide nanocompositeInt J Biol Macromol201468333824769214
  • JamesCJohnsonALJenkinsATAntimicrobial surface grafted thermally responsive PNIPAM-co-ALA nano-gelsChem Commun201147481277712779
  • ManjulaBVaraprasadKSadikuRRamamKReddyGVSRajuKMDevelopment of microbial resistant thermosensitive Ag nanocomposite (gelatin) hydrogels via green processJ Biomed Mater Res A2014102492893423650266
  • ZafarMShahTRawalASioresEPreparation and characterisation of thermoresponsive nanogels for smart antibacterial fabricsMater Sci Eng C201440135141
  • BoonkaewBKempfMKimbleRSupapholPCuttleLAntimicrobial efficacy of a novel silver hydrogel dressing compared to two common silver burn wound dressings: acticoat and PolyMem Silver((R))Burns2014401899623790588
  • BoonkaewBSuwanpreuksaPCuttleLBarberPMSupapholPHydrogels containing silver nanoparticles for burn wounds show antimicrobial activity without cytotoxicityJ Appl Polyme Sci201413140215
  • BozaciEAkarEOzdoganEDemirAAltinisikASekiYApplication of carboxymethylcellulose hydrogel based silver nanocomposites on cotton fabrics for antibacterial propertyCarbohydr Polym201513412813526428108
  • RahoRPaladiniFLombardiFABoccarellaSZuninoBPolliniMIn-situ photo-assisted deposition of silver particles on hydrogel fibers for antibacterial applicationsMater Sci Eng C Mater Biol Appl201555424926117737
  • LeeW-FTsaoK-TEffect of silver nanoparticles content on the various properties of nanocomposite hydrogels by in situ polymerizationJ Sci Mater20094518997
  • WuJHouSRenDMatherPTAntimicrobial properties of nanostructured hydrogel webs containing silverBiomacromolecules20091092686269319681604
  • EidMEl-ArnaoutyMBSalahMSolimanE-SHegazyE-SARadiation synthesis and characterization of poly(vinyl alcohol)/poly(N-vinyl-2-pyrrolidone) based hydrogels containing silver nanoparticlesJ Polym Res2012193
  • BajpaiSChandNMahendraMIn situ formation of silver nanoparticles in poly (methacrylic acid) hydrogel for antibacterial applicationsPolym Eng Sci201353817511759
  • MicicMMilicTVMitricMJokicBSuljovrujicERadiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly (2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogelsPolym Bull2013701233473357
  • WeiQ-BFuFZhangY-QTangLPreparation, characterization, and antibacterial properties of pH-responsive P(MMA-co-MAA)/silver nanocomposite hydrogelsJ Polym Res2014212349
  • BhowmickSMohantySKoulVFabrication of transparent quaternized PVA/silver nanocomposite hydrogel and its evaluation as an antimicrobial patch for wound care systemsJ Mater Sci Mater Med2016271116027638099
  • MalcherMVolodkinDHeurtaultBEmbedded silver ions-containing liposomes in polyelectrolyte multilayers: cargos films for antibacterial agentsLangmuir20082418102091021518698855
  • FullenkampDERiveraJGGongYKMussel-inspired silver-releasing antibacterial hydrogelsBiomaterials201233153783379122374454
  • JiaoTGuoHZhangQReduced graphene oxide-based silver nanoparticle-containing composite hydrogel as highly efficient dye catalysts for wastewater treatmentSci Rep201551187326183266
  • GradeSEberhardJNeumeisterASerum albumin reduces the antibacterial and cytotoxic effects of hydrogel-embedded colloidal silver nanoparticlesRSC Adv20122187190
  • XuLLiXTakemuraTHanagataNWuGChouLLGenotoxicity and molecular response of silver nanoparticle (NP)-based hydrogelJ Nanobiotechnol20121016111
  • YangCJungSYiHA biofabrication approach for controlled synthesis of silver nanoparticles with high catalytic and antibacterial activitiesBiochem Eng J20148981020
  • FaoucherENativoPBlackKIn situ preparation of network forming gold nanoparticles in agarose hydrogelsChem Commun2009436661
  • Daniel-da-SilvaALSalgueiroAMTrindadeTEffects of Au nanoparticles on thermoresponsive genipin-crosslinked gelatin hydrogelsGold Bull20134612533
  • ZhaoYJiangXMultiple strategies to activate gold nanoparticles as antibioticsNanoscale20135188340835023893008
  • BrownANSmithKSamuelsTALuJObareSOScottMENanoparticles functionalized with ampicillin destroy multiple-antibiotic-resistant isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and methicillin-resistant Staphylococcus aureusAppl Environ Microbiol2012788276822286985
  • GuineyLMAgnelloADThomasJCTakatoriKFlynnNTThermoresponsive behavior of charged N-isopropylacrylamide-based hydrogels containing gold nanostructuresColloid Polym Sci20092875601608
  • KozlovskayaVKharlampievaEChangSMuhlbauerRTsukrukVVpH-responsive layered hydrogel microcapsules as gold nanoreactorsChem Mater2009211021582167
  • GaoWVecchioDLiJHydrogel containing nanoparticlestabilized liposomes for topical antimicrobial deliveryACS Nano2014832900290724483239
  • RibeiroMFerrazMPMonteiroFJAntibacterial silk fibroin/nanohydroxyapatite hydrogels with silver and gold nanoparticles for bone regenerationNanomedicine201713123123927591960
  • JayaramuduTRaghavendraGMVaraprasadKSadikuRRajuKMDevelopment of novel biodegradable Au nanocomposite hydrogels based on wheat: for inactivation of bacteriaCarbohydr Polym20139222193220023399276
  • Ranga ReddyPVaraprasadKNarayana ReddyNMohana RajuKReddyNSFabrication of Au and Ag Bi-metallic nanocomposite for antimicrobial applicationsJ Appl Polym Scince2012125213571362
  • VaraprasadKSiva Mohan ReddyGJayaramuduJSadikuRRamamKRaySSDevelopment of microbial resistant Carbopol nanocomposite hydrogels via a green processBiomater Sci201422257
  • WeirELawlorAWhelanAReganFThe use of nanoparticles in antimicrobial materials and their characterizationAnalyst2008133783584518575632
  • HajipourMJFrommKMAshkarranAAAntibacterial properties of nanoparticlesTrends Biotechnol2012301049951122884769
  • WuSDuYHuYShiXZhangLAntioxidant and antimicrobial activity of xylan-chitooligomer-zinc complexFood Chem20131382–31312131923411248
  • JamesCPughTJohnsonALJenkinsATAAn antimicrobial zinc based molecule for cross linking poly-acrylic acidEur Polym J201147613381345
  • Sudheesh KumarPTLakshmananV-KAnilkumarTVFlexible and microporous chitosan hydrogel/nano ZnO composite bandages for wound dressing: in vitro and in vivo evaluationACS Appl Mater Interfaces2012452618262922489770
  • HashemMSharafSAbd El-HadyMMHebeishASynthesis and characterization of novel carboxymethylcellulose hydrogels and carboxymethylcellulolse-hydrogel-ZnO-nanocompositesCarbohydr Polym201395142142723618288
  • SchwartzVBThétiotFRitzSAntibacterial surface coatings from zinc oxide nanoparticles embedded in poly(N-isopropylacrylamide) hydrogel surface layersAdv Funct Mater2012221123762386
  • MohandasAKumarPTSRajaBLakshmananVKJayakumarRExploration of alginate hydrogel/nano zinc oxide composite bandages for infected woundsInt J Nanomed201510suppl 15366
  • YadollahiMGholamaliINamaziHAghazadehMSynthesis and characterization of antibacterial carboxymethyl cellulose/ZnO nanocomposite hydrogelsInt J Biol Macromol20157413614125524743
  • WangJHuHYangZWeiJLiJIPN hydrogel nanocomposites based on agarose and ZnO with antifouling and bactericidal propertiesMater Sci Eng C Mater Biol Appl20166137638626838864
  • Zare-AkbariZFarhadnejadHFurughi-NiaBAbedinSYadollahiMKhorsand-GhayeniMPH-sensitive bionanocomposite hydrogel beads based on carboxymethyl cellulose/ZnO nanoparticle as drug carrierInt J Biol Macromol201693pt A1317132727702657
  • YadollahiMFarhoudianSBarkhordariSGholamaliIFarhadnejadHMotasadizadehHFacile synthesis of chitosan/ZnO bio-nanocomposite hydrogel beads as drug delivery systemsInt J Biol Macromol20168227327826433177
  • WahidFYinJJXueDDSynthesis and characterization of antibacterial carboxymethyl Chitosan/ZnO nanocomposite hydrogelsInt J Biol Macromol20168827327927017980
  • HuangLDaiTXuanYTegosGPHamblinMRSynergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infectionsAntimicrobial Agents Chemother20115573432
  • FriedmanAJPhanJSchairerDOAntimicrobial and antiinflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogensJ Invest Dermatol20131335123123190896
  • FieldingGBoseSSiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivoActa Biomater20139119137914823871941
  • KumarNARejinoldNSAnjaliPBalakrishnanABiswasRJayakumarRPreparation of chitin nanogels containing nickel nanoparticlesCarbohydr Polym201397246947423911472
  • NarinGAlbayrakÇBÜlküSPreparation and characterization of antibacterial cobalt-exchanged natural zeolite/poly(vinyl alcohol) hydrogelsJ Sol-Gel Sci Technol2013691214230
  • KrukTSzczepanowiczKStefanskaJSochaRPWarszynskiPSynthesis and antimicrobial activity of monodisperse copper nanoparticlesColloids Surf B Biointerfaces2015128172225723345
  • IngleAPDuranNRaiMBioactivity, mechanism of action, and cytotoxicity of copper-based nanoparticles: a reviewAppl Microbiol Biotechnol20149831001100924305741
  • ZhongTOportoGSJaczynskiJJiangCNanofibrillated cellulose and copper nanoparticles embedded in polyvinyl alcohol films for antimicrobial applicationsBiomed Res Int2015201545683426137482
  • YadollahiMGholamaliINamaziHAghazadehMSynthesis and characterization of antibacterial carboxymethylcellulose/CuO bionanocomposite hydrogelsInt J Biol Macromol20157310911425605426
  • RajasekaranPSantraSHydrothermally treated chitosan hydrogel loaded with copper and zinc particles as a potential micronutrient- based antimicrobial feed additiveFront Vet Sci201526226664989
  • RamanujamKSundrarajanMAntibacterial effects of biosynthesized MgO nanoparticles using ethanolic fruit extract of Emblica officinalisJ Photochem Photobiol B Biol2014141296300
  • LeungYHNgAMXuXMechanisms of antibacterial activity of MgO: non-ROS mediated toxicity of MgO nanoparticles towards Escherichia coliSmall20141061171118324344000
  • HeYIngudamSReedSGehringAStrobaughTPJrIrwinPStudy on the mechanism of antibacterial action of magnesium oxide nanoparticles against foodborne pathogensJ Nanobiotechnol201614154
  • HezavehHMuhamadIIImpact of metal oxide nanoparticles on oral release properties of pH-sensitive hydrogel nanocompositesInt J Biol Macromol20125051334134022484730
  • NorowskiPAJrBumgardnerJDBiomaterial and antibiotic strategies for peri-implantitis: a reviewJ Biomed Mater Res B Appl Biomater200988253054318698626
  • GiltrapAMDowmanLJNagalingamGTotal synthesis of teixobactinOrg Lett20161811278827191730
  • MarshallHNew antibiotic discovered for Gram-positive bacteriaLancet Respir Med201532104104
  • AriasCAMurrayBEA new antibiotic and the evolution of resistanceN Engl J Med2015372121168117025785976
  • KellySThe drug pushScience2015348623785085325999488
  • FernandesPMartensEAntibiotics in late clinical developmentBiochem Pharmacol201713315216327687641
  • MontanariED’ArrigoGDi MeoCChasing bacteria within the cells using levofloxacin-loaded hyaluronic acid nanohydrogelsEur J Pharm Biopharm201487351852324642185
  • De GiglioECometaSRicciMACiprofloxacin-modified electrosynthesized hydrogel coatings to prevent titanium-implant- associated infectionsActa Biomater20117288289120659594
  • MarchesanSQuYWaddingtonLJSelf-assembly of ciprofloxacin and a tripeptide into an antimicrobial nanostructured hydrogelBiomaterials201334143678368723422591
  • DasDDasRGhoshPDharaSPandaABPalSDextrin cross linked with poly (HEMA): a novel hydrogel for colon specific delivery of ornidazoleRSC Adv20133472534025350
  • SinghBVarshneyLFrancisSRajneeshDesigning tragacanth gum based sterile hydrogel by radiation method for use in drug delivery and wound dressing applicationsInt J Biol Macromol20168858660227020943
  • AnderssonDIHughesDPersistence of antibiotic resistance in bacterial populationsFEMS Microbiol Rev201135590191121707669
  • Rodriguez-RojasARodriguez-BeltranJCouceABlazquezJAntibiotics and antibiotic resistance: a bitter fight against evolutionInt J Med Microbiol20133036–729329723517688
  • van HoekAHMeviusDGuerraBMullanyPRobertsAPAartsHJAcquired antibiotic resistance genes: an overviewFront Microbiol2011220322046172
  • MoltonJSTambyahPAAngBSLingMLFisherDAThe global spread of healthcare-associated multidrug-resistant bacteria: a perspective from AsiaClin Infect Dis20135691310131823334810
  • HosnyKMCiprofloxacin as ocular liposomal hydrogelAAPS PharmSciTech201011124124620151337
  • LequeuxIDucasseEJouenneTThebaultPAddition of antimicrobial properties to hyaluronic acid by grafting of antimicrobial peptideEur Polym J201451182190
  • BowenAHurdJHooverCImportation and domestic transmission of Shigella sonnei resistant to ciprofloxacin – United States, May 2014-February 2015MMWR Morb Mortal Wkly Rep2015641231832025837241
  • Chung TheHRabaaMASouth Asia as a reservoir for the global spread of ciprofloxacin-resistant Shigella sonnei: a cross-sectional studyPLoS Med2016138e100205527483136
  • BajpaiAKGuptaRMagnetically mediated release of ciprofloxacin from polyvinyl alcohol based superparamagnetic nanocompositesJ Mater Sci Mater Med201122235736921188482
  • ManjuSAntonyMSreenivasanKSynthesis and evaluation of a hydrogel that binds glucose and releases ciprofloxacinJ Sci Mater2010451540064012
  • SinghBSharmaNSharmaVSlow release of ciprofloxacin from double potential drug delivery systemJ Sci Mater201046825872599
  • ZhouXHWeiDXYeHMZhangXMengXZhouQDevelopment of poly(vinyl alcohol) porous scaffold with high strength and well ciprofloxacin release efficiencyMater Sci Eng C Mater Biol Appl20166732633527287128
  • DasDGhoshPDharaSPandaABPalSDextrin and poly(acrylic acid)-based biodegradable, non-cytotoxic, chemically cross-linked hydrogel for sustained release of ornidazole and ciprofloxacinACS Appl Mater Interfaces2015784791480325654747
  • DasDPalSDextrin/poly (HEMA): pH responsive porous hydrogel for controlled release of ciprofloxacinInt J Biol Macromol20157217117825138539
  • WuTZhangQRenWControlled release of gentamicin from gelatin/genipin reinforced beta-tricalcium phosphate scaffold for the treatment of osteomyelitisJ Mater Chem B20131263304
  • LvYFWangJDongFYangDHMeta-analysis of local gentamicin for prophylaxis of surgical site infections in colorectal surgeryInt J Colorectal Dis201631239340226614505
  • MustersGDBurgerJWBuskensCJBemelmanWATanisPJLocal application of gentamicin in the prophylaxis of perineal wound infection after abdominoperineal resection: a systematic reviewWorld J Surg201539112786279426170157
  • SinghBPalLSterculia crosslinked PVA and PVA-poly(AAm) hydrogel wound dressings for slow drug delivery: mechanical, mucoadhesive, biocompatible and permeability propertiesJ Mech Behav Biomed Mater2012992122498279
  • SinghBSharmaSDhimanADesign of antibiotic containing hydrogel wound dressings: biomedical properties and histological study of wound healingInt J Pharm20134571829124075861
  • LiHYangJHuXLiangJFanYZhangXSuperabsorbent polysaccharide hydrogels based on pullulan derivate as antibacterial release wound dressingJ Biomed Mater Res A2011981313921523902
  • NnamaniPOKenechukwuFCDibuaEUOgbonnaCCMonemehULAttamaAATransdermal microgels of gentamicinEur J Pharm Biopharm201384234535423220381
  • OverstreetDMcLarenACalaraFVernonBMcLemoreRLocal gentamicin delivery from resorbable viscous hydrogels is therapeutically effectiveClin Orthop Relat Res2015473133734725227556
  • WuFMengGHeJWuYWuFGuZAntibiotic-loaded chitosan hydrogel with superior dual functions: antibacterial efficacy and osteoblastic cell responsesACS Appl Mater Interfaces2014613100051001324938653
  • DoratiRDe TrizioAGentaIMerelliAModenaTContiBGentamicin-loaded thermosetting hydrogel and moldable composite scaffold: formulation study and biologic evaluationJ Pharm Sci201710661596160728283432
  • LovatiABDragoLBottagisioMSystemic and local administration of antimicrobial and cell therapies to prevent methicillin-resistant Staphylococcus epidermidis-induced femoral nonunions in a rat modelMediators Inflamm20162016959570627478310
  • NgKMabasaVHChowIEnsomMHSystematic review of efficacy, pharmacokinetics, and administration of intraventricular vancomycin in adultsNeurocrit Care201420115817123090839
  • WalshTRWeeksJLivermoreDMTolemanMADissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence studyLancet Infect Dis201111535536221478057
  • JakovacSBojicEFIbrisimovicMATutisBOstojicMHukicMCharacteristics of vancomycin-resistant enterococcus strains in the west balkans: a first reportMicrob Drug Resist201723112212627351410
  • YangJJiangYGuoLYeLMaYLuoYPrevalence of diverse clones of vancomycin-resistant Enterococcus faecium ST78 in a Chinese hospitalMicrob Drug Resist201622429430026652286
  • SimoesSMVeigaFTorres-LabandeiraJJSyringeable pluronicalpha-cyclodextrin supramolecular gels for sustained delivery of vancomycinEur J Pharm Biopharm201280110311222005155
  • ZhaoYZhangXWangYIn situ cross-linked polysaccharide hydrogel as extracellular matrix mimics for antibiotics deliveryCarbohydr Polym2014105636924708953
  • PakzadYGanjiFThermosensitive hydrogel for periodontal application: in vitro drug release, antibacterial activity and toxicity evaluationJ Biomater Appl201630791992926686586
  • GustafsonCTBoakye-AgyemanFBrinkmanCLControlled delivery of vancomycin via charged hydrogelsPLoS One2016111e014640126760034
  • LakesALPeyyalaREbersoleJLPuleoDAHiltJZDziublaTDSynthesis and characterization of an antibacterial hydrogel containing covalently bound vancomycinBiomacromolecules20141583009301825000243
  • ZhangJ-ZXiaoC-SWangJ-CZhuangX-LChenX-SPhoto cross- linked biodegradable hydrogels for enhanced vancomycin loading and sustained releaseChin J Polym Sci2013311216971705
  • Guzman-TrampeSCeapaCDManzo-RuizMSanchezSSynthetic biology era: improving antibiotic’s worldBiochem Pharmacol20171349911328159623
  • FordACFormanDHuntRHYuanYMoayyediPHelicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trialsBMJ2014348g317424846275
  • VaghaniSSPatelMMSatishCSSynthesis and characterization of pH-sensitive hydrogel composed of carboxymethyl chitosan for colon targeted delivery of ornidazoleCarbohydr Res20123471768222099382
  • DasDGhoshPGhoshAStimulus-responsive, biodegradable, biocompatible, covalently cross-linked hydrogel based on dextrin and Poly(N-isopropylacrylamide) for in vitro/in vivo controlled drug releaseACS Appl Mater Interfaces2015726143381435126069986
  • ChenTChenLLiHDesign and in vitro evaluation of a novel poly(methacrylic acid)/metronidazole antibacterial nanogel as an oral dosage formColloids Surf B Biointerfaces2014118C6571
  • SamantaHSRaySKControlled release of tinidazole and theophylline from chitosan based composite hydrogelsCarbohydr Polym201410610912024721057
  • El-MahroukGMAboul-EinienMHMakhloufAIDesign, optimization, and evaluation of a novel metronidazole-loaded gastroretentive pH-sensitive hydrogelAAPS PharmSciTech20161761285129726689404
  • LboutounneHChauletJ-FPlotonCFalsonFPirotFSustained ex vivo skin antiseptic activity of chlorhexidine in poly (ε-caprolactone) nanocapsule encapsulated form and as a digluconateJ Controll Rel2002822319334
  • JiQXZhaoQSDengJLuRA novel injectable chlorhexidine thermosensitive hydrogel for periodontal application: preparation, antibacterial activity and toxicity evaluationJ Mater Sci Mater Med20102182435244220502948
  • JonesDSLorimerCPMcCoyCPGormanSPCharacterization of the physicochemical, antimicrobial, and drug release properties of thermoresponsive hydrogel copolymers designed for medical device applicationsJ Biomed Mater Res B Appl Biomater200885241742617979187
  • MorelliLCappellutiMARicottiLLenardiCGergesIAn injectable system for local and sustained release of antimicrobial agents in the periodontal pocketMacromol Biosci Epub201752
  • MoritzSWiegandCWesargFActive wound dressings based on bacterial nanocellulose as drug delivery system for octenidineInt J Pharm20144711–2455524792978
  • GlisoniRJGarcia-FernandezMJPinoMBeta-Cyclodextrin hydrogels for the ocular release of antibacterial thiosemicarbazonesCarbohydr Polym201393244945723499082
  • SittiwongJNiamlangSParadeeNSirivatAElectric field-controlled benzoic acid and sulphanilamide delivery from poly(vinyl alcohol) hydrogelAAPS PharmSciTech20121341407141523065453
  • YunokiSKohtaMOhyabuYSekiguchiMKuboTIwasakiTElectrostatic immobilization of cetylpyridinium chloride to poly (vinyl alcohol) hydrogels for the simple fabrication of wound dressings with the suppressed release of antibacterial agentsJ Appl Polym Sci201413140456
  • NhoY-CLimY-MGwonH-JChoiE-KPreparation and characterization of PVA/PVP/glycerin/antibacterial agent hydrogels using γ-irradiation followed by freeze-thawingKorean J Chem Eng200926616751678
  • VogtPMReimerKHauserJPVP-iodine in hydrosomes and hydrogel – a novel concept in wound therapy leads to enhanced epithelialization and reduced loss of skin graftsBurns200632669870516837138
  • ZhaoCLiXLiLChengGGongXZhengJDual functionality of antimicrobial and antifouling of poly(N-hydroxyethylacrylamide)/salicylate hydrogelsLangmuir20132951517152423317290
  • MaDCaiXLinQAlginate hydrogel sphere improves the alkali and heat resistances of isothiazolinones with long – term antibacterial activityJ Appl Polym Sci2013130315541561
  • LvZFWangFCZhengHLMeta-analysis: is combination of tetracycline and amoxicillin suitable for Helicobacter pylori infection?World J Gastroenterol20152182522253325741163
  • SelvakumaranSMuhamadIIAbd RazakSIEvaluation of kappa carrageenan as potential carrier for floating drug delivery system: effect of pore forming agentsCarbohydr Polym201613520721426453870
  • ChangCHLinYHYehCLNanoparticles incorporated in pH-sensitive hydrogels as amoxicillin delivery for eradication of Helicobacter pyloriBiomacromolecules201011113314219924885
  • MoogooeeMRamezanzadehHJasooriSOmidiYDavaranSSynthesis and in vitro studies of cross-linked hydrogel nanoparticles containing amoxicillinJ Pharm Sci201110031057106621280053
  • KamounEAKenawyE-RSTamerTMEl-MeligyMAMohy EldinMSPoly (vinyl alcohol)-alginate physically crosslinked hydrogel membranes for wound dressing applications: characterization and bioevaluationArab J Chem2013813847
  • GrohsPPodglajenIGuerotEAssessment of five screening strategies for optimal detection of carriers of third-generation cephalosporin-resistant Enterobacteriaceae in intensive care units using daily samplingClin Microbiol Infect20142011O879O88624807791
  • AttaSKhaliqSIslamAInjectable biopolymer based hydrogels for drug delivery applicationsInt J Biol Macromol20158024024526118484
  • VenugopalaraoGSreenivas GowthamMSaradaNCFormulation evaluation and stability studies of hydrogel tablets containing Cefditoren PivoxilJ Pharm Res201373230234
  • LaiPLHongDWKuKLLaiZTChuIMNovel thermosensitive hydrogels based on methoxy polyethylene glycol-co-poly(lactic acid-co-aromatic anhydride) for cefazolin deliveryNanomedicine201410355356024096031
  • IslanGADiniCBartelLCBolzanADCastroGRCharacterization of smart auto-degradative hydrogel matrix containing alginate lyase to enhance levofloxacin delivery against bacterial biofilmsInt J Pharm2015496295396426505149
  • LiYZhouFWenY(−)-Menthol based thixotropic hydrogel and its application as a universal antibacterial carrierSoft Matter20141017307724695880
  • HeGChenXYinYPreparation and antibacterial properties of O-carboxymethyl chitosan/lincomycin hydrogelsJ Biomater Sci Polym Ed201627437038426675323
  • HeZ-XWangZ-HZhangH-HDoxycycline and hydroxypropyl- β-cyclodextrin complex in poloxamer thermal sensitive hydrogel for ophthalmic deliveryActa Pharmaceutica Sinica B201114254260
  • TormosCJAbrahamCMadihallySVImproving the stability of chitosan-gelatin-based hydrogels for cell delivery using transglutaminase and controlled release of doxycyclineDrug Deliv Transl Res20155657558426373948
  • HurlerJBergOASkarMConradiAHJohnsenPJSkalko-BasnetNImproved burns therapy: liposomes-in-hydrogel delivery system for mupirocinJ Pharm Sci2012101103906391522777770
  • HurlerJSorensenKKFallareroAVuorelaPSkalko-BasnetNLiposomes-in-hydrogel delivery system with mupirocin: in vitro antibiofilm studies and in vivo evaluation in mice burn modelBiomed Res Int2013201349848524369533
  • PengKTChenCFChuIMTreatment of osteomyelitis with teicoplanin-encapsulated biodegradable thermosensitive hydrogel nanoparticlesBiomaterials201031195227523620381140
  • NafeeNYoussefAEl-GowelliHAsemHKandilSAntibiotic-free nanotherapeutics: hypericin nanoparticles thereof for improved in vitro and in vivo antimicrobial photodynamic therapy and wound healingInt J Pharm2013454124925823834835
  • LaiWFRogachALHydrogel-based materials for delivery of herbal medicinesACS Appl Mater Interfaces2017913113091132028244320
  • TanSPMcLoughlinPO’SullivanLDevelopment of a novel antimicrobial seaweed extract-based hydrogel wound dressingInt J Pharm20134561102023958753
  • VarshneyLRole of natural polysaccharides in radiation formation of PVA–hydrogel wound dressingNucl Instrum Methods Phys Res B20072552343349
  • EngelHKaoSWLarsonJInvestigation of Dermis-derived hydrogels for wound healing applicationsBiomed J2015381586425179708
  • PengC-WLinH-YWangH-WWuW-WThe influence of operating parameters on the drug release and anti-bacterial performances of alginate wound dressings prepared by three-dimensional plottingMater Sci Eng C201232824912500
  • PirakTJangchudAJantawatPCharacterisation of physical, chemical and antimicrobial properties of allicin-chitosan complexesInt J Food Sci Technol201247713391347
  • QureshiMAKhatoonFRizviMAZafaryabMEthyl acetate Salix alba leaves extract-loaded chitosan-based hydrogel film for wound dressing applicationsJ Biomater Sci Polym Ed201526181452146426525493
  • CaseroCMachinFMendez-AlvarezSStructure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioidesJ Nat Prod20157819310225517209
  • BasniwalRKButtarHSJainVKJainNCurcumin nanoparticles: preparation, characterization, and antimicrobial studyJ Agric Food Chem20115952056206121322563
  • VaraprasadKMohanYMVimalaKMohana RajuKSynthesis and characterization of hydrogel-silver nanoparticle-curcumin composites for wound dressing and antibacterial applicationJ Appl Polym Sci20111212784796
  • RavindraSMulaba-BafubiandiAFRajinikanthVVaraprasadKNarayana ReddyNMohana RajuKDevelopment and characterization of curcumin loaded silver nanoparticle hydrogels for antibacterial and drug delivery applicationsJ Inorg Organometal Polym Mater201222612541262
  • Sierra-GarciaGDCastro-RiosRGonzalez-HortaALara-AriasJChavez-MontesAAcemannan, an extracted polysaccharide from Aloe vera: a literature reviewNat Prod Commun2014981217122125233608
  • CelliniLDi BartolomeoSDi CampliEGenoveseSLocatelliMDi GiulioMIn vitro activity of Aloe vera inner gel against Helicobacter pylori strainsLett Appl Microbiol2014591434824597562
  • PereiraRFBartoloPJTraditional therapies for skin wound healingAdv Wound Care (New Rochelle)20165520822927134765
  • SeowYXYeoCRChungHLYukHGPlant essential oils as active antimicrobial agentsCrit Rev Food Sci Nutr201454562564424261536
  • VergisJGokulakrishnanPAgarwalRKKumarAEssential oils as natural food antimicrobial agents: a reviewCrit Rev Food Sci Nutr201555101320132324915323
  • LiakosIRizzelloLScurrDJPompaPPBayerISAthanassiouAAll-natural composite wound dressing films of essential oils encapsulated in sodium alginate with antimicrobial propertiesInt J Pharm2014463213714524211443
  • YusofNAinul HafizaAHZohdiRMBakarMZADevelopment of honey hydrogel dressing for enhanced wound healingRadiat Phys Chem20077611–1217671770
  • QiaoMChenDHaoTZhaoXHuHMaXEffect of bee venom peptide-copolymer interactions on thermosensitive hydrogel delivery systemsInt J Pharm20073451–211612417629639
  • ZhangSBorazjaniRNSalamoneJCAhearnDGCrowSAJrPierceGEIn vitro deposition of lysozyme on etafilcon A and balafilcon A hydrogel contact lenses: effects on adhesion and survival of Pseudomonas aeruginosa and Staphylococcus aureusCont Lens Anterior Eye200528311311916318841
  • LeeALZNgVWLWangWXHedrickJLYangYYBlock copolymer mixtures as antimicrobial hydrogels for biofilm eradicationBiomaterials20133438102781028624090835
  • SpasojevicDZmejkoskiDGlamoclijaJLignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatmentInt J Antimicrob Agents201648673273527742207
  • GaoPNieXZouMShiYChengGRecent advances in materials for extended-release antibiotic delivery systemJ Antibiot201164962563421811264
  • PalzaHAntimicrobial polymers with metal nanoparticlesInt J Mol Sci20151612099211625607734
  • SuiXFengXDi LucaAPoly (N-isopropylacrylamide)–poly (ferrocenylsilane) dual-responsive hydrogels: synthesis, characterization and antimicrobial applicationsPolym Chem201342337342
  • JiangQXuJLiTQiaoCLiYSynthesis and antibacterial activities of quaternary ammonium salt of gelatinJ Macromol Sci B2014531133141
  • TomićSLMićićMMDobićSNFilipovićJMSuljovrujićEHSmart poly(2-hydroxyethyl methacrylate/itaconic acid) hydrogels for biomedical applicationRadiat Phys Chem2010795643649
  • LaY-HMcCloskeyBDSooriyakumaranRBifunctional hydrogel coatings for water purification membranes: improved fouling resistance and antimicrobial activityJ Memb Sci20113721–2285291
  • ParsonsCMcCoyCPGormanSPAnti-infective photodynamic biomaterials for the prevention of intraocular lens-associated infectious endophthalmitisBiomaterials200930459760218996591
  • HalpennyGMSteinhardtRCOkialdaKAMascharakPKCharacterization of pHEMA-based hydrogels that exhibit light-induced bactericidal effect via release of NOJ Mater Sci Mater Med200920112353236019554428
  • FjellCDHissJAHancockRESchneiderGDesigning antimicrobial peptides: form follows functionNat Rev Drug Discov2011111375122173434
  • BrogdenKAAntimicrobial peptides: pore formers or metabolic inhibitors in bacteria?Nat Rev Microbiol20053323825015703760
  • Lakshmaiah NarayanaJChenJYAntimicrobial peptides: possible anti-infective agentsPeptides201572889426048089
  • SalickDAKretsingerJKPochanDJSchneiderJPInherent antibacterial activity of a peptide-based β-hairpin hydrogelJ Am Chem Soc200712947147931479917985907
  • VeigaASSinthuvanichCGasparDFranquelimHGCastanhoMARBSchneiderJPArginine-rich self-assembling peptides as potent antibacterial gelsBiomaterials201233358907891622995710
  • LiuYYangYWangCZhaoXStimuli-responsive self-assembling peptides made from antibacterial peptidesNanoscale20135146413642123739953
  • CleophasRTSjollemaJBusscherHJKruijtzerJALiskampRMCharacterization and activity of an immobilized antimicrobial peptide containing bactericidal PEG-hydrogelBiomacromolecules20141593390339525109707
  • LiY-QHanQFengJ-LTianW-LMoH-ZAntibacterial characteristics and mechanisms of ε-poly-lysine against Escherichia coli and Staphylococcus aureusFood Control2014432227
  • ZhouCLiPQiXA photopolymerized antimicrobial hydrogel coating derived from epsilon-poly-l-lysineBiomaterials201132112704271221257199
  • JiangLXuDSellatiTJDongHSelf-assembly of cationic multidomain peptide hydrogels: supramolecular nanostructure and rheological properties dictate antimicrobial activityNanoscale2015745191601916926524425
  • LavertyGGormanSPGilmoreBFAntimicrobial peptide incorporated poly(2-hydroxyethyl methacrylate) hydrogels for the prevention of Staphylococcus epidermidis-associated biomaterial infectionsJ Biomed Mater Res A201210071803181422489028
  • BaranovaOKuz’minNSamsonovaTMedical hydrogels based on bioactive compounds. Synthesis, properties, and possible application for preparing bactericidal materialsFibre Chem201143190103
  • SteckbeckJDDeslouchesBMontelaroRCAntimicrobial peptides: new drugs for bad bugs?Expert Opin Biol Ther2014141111424206062
  • AshbyMPetkovaAHilpertKCationic antimicrobial peptides as potential new therapeutic agents in neonates and children: a reviewCurr Opin Infect Dis201427325826724722240
  • ForbesSMcBainAJFelton-SmithSJowittTABirchenoughHLDobsonCBComparative surface antimicrobial properties of synthetic biocides and novel human apolipoprotein E derived antimicrobial peptidesBiomaterials201334225453546423623325
  • PletzerDHancockREAntibiofilm peptides: potential as broad- spectrum agentsJ Bacteriol2016198192572257827068589
  • SongARaneAAChristmanKLAntibacterial and cell-adhesive polypeptide and poly(ethylene glycol) hydrogel as a potential scaffold for wound healingActa Biomater201281415022023748
  • BuhrmanJSCookLCRayahinJEFederleMJGemeinhartRAProteolytically activated anti-bacterial hydrogel microspheresJ Control Rel20131713288295
  • XieZAphaleNVKadapureTDDesign of antimicrobial peptides conjugated biodegradable citric acid derived hydrogels for wound healingJ Biomed Mater Res A2015103123907391826014899
  • MelchionnaMStyanKEMarchesanSThe unexpected advantages of using D-amino acids for peptide self-assembly into nanostructured hydrogels for medicineCurr Top Med Chem201616182009201826876522
  • LiuLHuangYRiduanSNMain-chain imidazolium oligomer material as a selective biomimetic antimicrobial agentBiomaterials201233338625863122902059
  • LocockKEMichlTDValentinJDGuanylated polymethacrylates: a class of potent antimicrobial polymers with low hemolytic activityBiomacromolecules20131411402124099527
  • LienkampKKumarKNSomANüssleinKTewGN“Doubly selective” antimicrobial polymers: how do they differentiate between bacteria?Chemistry20091543117101171419790208
  • ThakerHDCankayaAScottRWTewGNRole of amphiphilicity in the design of synthetic mimics of antimicrobial peptides with Gram- negative activityAcs Med Chem Lett20134548123814644
  • LiuRChenXHayoukaZNylon-3 polymers with selective antifungal activityJ Am Chem Soc2013135145270527323547967
  • ChakrabortySLiuRLemkeJJEffects of cyclic vs. acyclic hydrophobic subunits on the chemical structure and biological properties of nylon-3 co-polymersAcs Macro Lett201128753756
  • NgVWKeXLeeALHedrickJLYangYYSynergistic co-delivery of membrane-disrupting polymers with commercial antibiotics against highly opportunistic bacteriaAdv Mater Deerfield2013254667306736
  • EnglerACTanJPOngZYAntimicrobial polycarbonates: investigating the impact of balancing charge and hydrophobicity using a same-centered polymer approachBiomacromolecules20131412433124228904
  • ChinWYangCNgVWLBiodegradable broad-spectrum antimicrobial polycarbonates: investigating the role of chemical structure on activity and selectivityMacromolecules2014462287978807
  • JiangSCaoZUltralow-fouling, functionalizable, and hydrolyzable zwitterionic materials and their derivatives for biological applicationsAdv Mater Deerfield2010229920
  • CaoZJiangSSuper-hydrophilic zwitterionic poly(carboxybetaine) and amphiphilic non-ionic poly(ethylene glycol) for stealth nanoparticlesNano Today201275404413
  • MiLJiangSSynchronizing nonfouling and antimicrobial properties in a zwitterionic hydrogelBiomaterials201233358928893322999466
  • LiuSQYangCHuangYAntimicrobial and antifouling hydrogels formed in situ from polycarbonate and poly(ethylene glycol) via Michael additionAdv Mater Deerfield2012244864846489
  • LiXDongQHePSynthesis and water absorbency of polyampholytic hydrogels with antibacterial activityJ Appl Polym Sci20091121439446
  • DebnathSShomeADasDDasPKHydrogelation through self- assembly of Fmoc-peptide functionalized cationic amphiphiles: potent antibacterial agentJ Phys Chem B2010114134407441520297770
  • DuttaSKarTMandalDDasPKStructure and properties of cholesterol-based hydrogelators with varying hydrophilic terminals: biocompatibility and development of antibacterial soft nanocompositesLangmuir201329131632723214716
  • BernetABehrMSchmidtH-WSupramolecular hydrogels based on antimycobacterial amphiphilesSoft Matter20128184873
  • BursaliEACoskunSKizilMYurdakocMSynthesis, characterization and in vitro antimicrobial activities of boron/starch/polyvinyl alcohol hydrogelsCarbohydr Polym201183313771383
  • Nazarzadeh ZareEMansour LakourajMMohseniMBiodegradable polypyrrole/dextrin conductive nanocomposite: synthesis, characterization, antioxidant and antibacterial activitySynth Met2014187916
  • WangHWilkschJJLithgowTStrugnellRAGeeMLNanomechanics measurements of live bacteria reveal a mechanism for bacterial cell protection: the polysaccharide capsule in Klebsiella is a responsive polymer hydrogel that adapts to osmotic stressSoft Matter20139317560
  • SangLYZhouXHYunFZhangGLEnzymatic synthesis of chitosan-gelatin antimicrobial copolymer and its characterisationJ Sci Food Agric2010901586420355012
  • DingFNieZDengHXiaoLDuYShiXAntibacterial hydrogel coating by electrophoretic co-deposition of chitosan/alkynyl chitosanCarbohydr Polym20139821547155224053838
  • StracciaMCd’AyalaGGRomanoIOlivaALaurienzoPAlginate hydrogels coated with chitosan for wound dressingMar Drugs20151352890290825969981
  • FanLYangJWuHPreparation and characterization of quaternary ammonium chitosan hydrogel with significant antibacterial activityInt J Biol Macromol20157983083625895959
  • LiuBHuJMengQNonwoven supported temperature-sensitive poly(N-isopropylacrylamide)/polyurethane copolymer hydrogel with antibacterial activityJ Biomed Mater Res B Appl Biomater20098911818688797
  • NoppakundilogratSSonjaipanichKThongchulNKiatkamjornwongSSyntheses, characterization, and antibacterial activity of chitosan grafted hydrogels and associated mica-containing nanocomposite hydrogelsJ Appl Polym Sci2013127649274938
  • SalickDAPochanDJSchneiderJPDesign of an injectable β-hairpin peptide hydrogel that kills Methicillin-resistant Staphylococcus aureusAdv Mater Deerfield2010214141204123
  • HughesMDebnathSKnappCWUlijnRVAntimicrobial properties of enzymatically triggered self-assembling aromatic peptide amphiphilesBiomaterialsence201311111381142
  • SatarkarNSHawkinsAMHiltJZHydrogel nanocomposites in biology and medicine: applications and interactionsPuleoDBiziosRBiological Interactions on Materials SurfacesNew YorkSpringer2009319342
  • ReithoferMRLakshmananAPingATChinJMHauserCAIn situ synthesis of size-controlled, stable silver nanoparticles within ultrashort peptide hydrogels and their anti-bacterial propertiesBiomaterials201435267535754224933510
  • EidMGamma radiation synthesis and characterization of starch based polyelectrolyte hydrogels loaded silver nanoparticlesJ Inorg Organometal Polym Mater2011212297305
  • DuttaSShomeAKarTDasPKCounterion-induced modulation in the antimicrobial activity and biocompatibility of amphiphilic hydrogelators: influence of in-situ-synthesized Ag-nanoparticle on the bactericidal propertyLangmuir20112785000500821446701
  • ShomeADuttaSMaitiSDasPKIn situ synthesized Ag nanoparticle in self-assemblies of amino acid based amphiphilic hydrogelators: development of antibacterial soft nanocompositesSoft Matter2011763011
  • GhavamiNejadAParkCHKimCSIn situ synthesis of antimicrobial silver nanoparticles within antifouling zwitterionic hydrogels by catecholic redox chemistry for wound healing applicationBiomacromolecules20161731213122326891456
  • LiuYMaWLiuWSilver(i)–glutathione biocoordination polymer hydrogel: effective antibacterial activity and improved cytocompatibilityJ Mater Chem2011214819214
  • AnjumSGuptaASharmaDDevelopment of novel wound care systems based on nanosilver nanohydrogels of polymethacrylic acid with Aloe vera and curcuminMater Sci Eng C Mater Biol Appl20166415716627127040
  • VasileBSOpreaOVoicuGSynthesis and characterization of a novel controlled release zinc oxide/gentamicin-chitosan composite with potential applications in wounds careInt J Pharm2014463216116924291078
  • RouabhiaMAsselinJTaziNMessaddeqYLevinsonDZhangZProduction of biocompatible and antimicrobial bacterial cellulose polymers functionalized by RGDC grafting groups and gentamicinACS Appl Mater Interfaces2014631439144624422537
  • ParadisoPSerroAPSaramagoBColacoRChauhanAControlled release of antibiotics from vitamin E-loaded silicone-hydrogel contact lensesJ Pharm Sci201610531164117226886333
  • ReedTPThomasLAWeerenFRRuthJDAndersBBA novel dextran polymer hydrogel local antimicrobial therapy in dogs: a pilot studyCan Vet J201657218919526834272
  • NovacOLisaGProfireLTuchilusCPopaMIAntibacterial quaternized gellan gum based particles for controlled release of ciprofloxacin with potential dermal applicationsMater Sci Eng C201435291299
  • BardajeeGRHooshyarZRezanezhadHA novel and green biomaterial based silver nanocomposite hydrogel: synthesis, characterization and antibacterial effectJ Inorg Biochem201211736737322818024
  • YadollahiMFarhoudianSNamaziHOne-pot synthesis of antibacterial chitosan/silver bio-nanocomposite hydrogel beads as drug delivery systemsInt J Biol Macromol201579374325931399