Folic acid-modified ginsenoside Rg5-loaded bovine serum albumin nanoparticles for targeted cancer therapy in vitro and in vivo

References

• Mun EJ, Babiker HM, Weinberg U, Kirson ED, Von Hoff DD. Tumor-treating fields: a fourth modality in cancer treatment. Clin Cancer Res. 2018;24(2):266. doi:10.1158/1078-0432.CCR-17-111728765323
   PubMed Web of Science ®Google Scholar
• Partridge AH, Elmore JG, Saslow D, McCaskill-Stevens W, Schnitt SJ. Challenges in ductal carcinoma in situ risk communication and decision-making: report from an American Cancer Society and National Cancer Institute workshop. CA Cancer J Clin. 2012;62(3):203–210. doi:10.3322/caac.2114022488610
   PubMedGoogle Scholar
• Oun R, Moussa YE, Wheate NJ. The side effects of platinum-based chemotherapy drugs: a review for chemists. Dalton Trans. 2018;47(19):6645–6653. doi:10.1039/c8dt00838h29632935
   PubMed Web of Science ®Google Scholar
• Tamura T, Miyazaki K, Shiozawa T, Satoh H. Comparative effectiveness and resource usage in patients receiving first-line taxol-based chemotherapy for stage IV NSCLC. Clin Lung Cancer. 2018;19(1):e67. doi:10.1016/j.cllc.2017.06.01828739317
   PubMedGoogle Scholar
• Duan L, Xiong X, Hu J, Liu Y, Li J, Wang J. Panax notoginseng saponins for treating coronary artery disease: a functional and mechanistic overview. Front Pharmacol. 2017;8:702. doi:10.3389/fphar.2017.0070229089889
   PubMed Web of Science ®Google Scholar
• Wang T, Guo R, Zhou G, et al. Traditional uses, botany, phytochemistry, pharmacology and toxicology of Panax notoginseng (Burk.) F.H. Chen: a review. J Ethnopharmacol. 2016;188:234–258. doi:10.1016/j.jep.2016.05.00527154405
   PubMed Web of Science ®Google Scholar
• Gillis CN. Panax ginseng pharmacology: a nitric oxide link? Biochem Pharmacol. 1997;54(1):1–8. doi:10.1016/s0006-2952(97)00193-79296344
   PubMed Web of Science ®Google Scholar
• Shin YW, Bae EA, Kim DH. Inhibitory effect of ginsenoside Rg5 and its metabolite ginsenoside Rh3 in an oxazolone-induced mouse chronic dermatitis model. Arch Pharm Res. 2006;29(8):685–690.16964764
   PubMed Web of Science ®Google Scholar
• Kim S-J, Kim AK. Anti-breast cancer activity of fine black ginseng (Panax ginseng Meyer) and ginsenoside Rg5. J Ginseng Res. 2015;39(2):125–134. doi:10.1016/j.jgr.2014.09.00326045685
   PubMedGoogle Scholar
• Li W, Yan M-H, Liu Y, et al. Ginsenoside Rg5 ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of inflammation, oxidative stress, and apoptosis. Nutrients. 2016;8(9):566. doi:10.3390/nu8090566
   PubMed Web of Science ®Google Scholar
• Liu Y, Fan D. Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model. Food Funct. 2018;9(11):5513–5527. doi:10.1039/c8fo01122b30207362
   PubMedGoogle Scholar
• Ahn S, Siddiqi MH, Aceituno VC, et al. Ginsenoside Rg5: rk1attenuates TNF-α/IFN-γ-induced production of thymus- and activation-regulated chemokine (TARC/CCL17) and LPS-induced NO production via downregulation of NF-κB/p38 MAPK/STAT1 signaling in human keratinocytes and macrophages. In Vitro Cell Dev Biol Anim. 2016;52(3):287–295. doi:10.1007/s11626-015-9983-y26714752
   PubMed Web of Science ®Google Scholar
• Hong C, Yang P, Li S, Guo Y, Wang D, Wang J. In Vitro/In vivo metabolism of ginsenoside Rg5 in rat using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry. Molecules. 2018;23(9):2113. doi:10.3390/molecules23092113
   PubMed Web of Science ®Google Scholar
• Sahu SK, Mallick SK, Santra S, Maiti TK, Ghosh SK, Pramanik P. In vitro evaluation of folic acid modified carboxymethyl chitosan nanoparticles loaded with doxorubicin for targeted delivery. J Mater Sci Mater Med. 2010;21(5):1587–1597. doi:10.1007/s10856-010-3998-420111985
   PubMed Web of Science ®Google Scholar
• Koo H, Min KH, Lee SC, et al. Enhanced drug-loading and therapeutic efficacy of hydrotropic oligomer-conjugated glycol chitosan nanoparticles for tumor-targeted paclitaxel delivery. J Control Release. 2013;172(3):823–831. doi:10.1016/j.jconrel.2013.08.29724035978
   PubMed Web of Science ®Google Scholar
• Danhier F, Feron O, Préat V. To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J Control Release. 2010;148(2):135–146. doi:10.1016/j.jconrel.2010.08.02720797419
   PubMed Web of Science ®Google Scholar
• Nosrati H, Sefidi N, Sharafi A, Danafar H, Manjili HK. Bovine Serum Albumin (BSA) coated iron oxide magnetic nanoparticles as biocompatible carriers for curcumin-anticancer drug. Bioorg Chem. 2018;76:501–509. doi:10.1016/j.bioorg.2017.12.03329310081
   PubMed Web of Science ®Google Scholar
• Elzoghby AO, Samy WM, Elgindy NA. Albumin-based nanoparticles as potential controlled release drug delivery systems. J Control Release. 2012;157(2):168–182. doi:10.1016/j.jconrel.2011.07.03121839127
   PubMed Web of Science ®Google Scholar
• Kim B, Lee C, Lee ES, Shin BS, Youn YS. Paclitaxel and curcumin co-bound albumin nanoparticles having antitumor potential to pancreatic cancer. Asian J Pharm Sci. 2016;11(6):708–714. doi:10.1016/j.ajps.2016.05.005
   Web of Science ®Google Scholar
• Fang J, Nakamura H, Maeda H. The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev. 2011;63(3):136–151. doi:10.1016/j.addr.2010.04.00920441782
   PubMed Web of Science ®Google Scholar
• Beik J, Khademi S, Attaran N, et al. A nanotechnology-based strategy to increase the efficiency of cancer diagnosis and therapy: folate-conjugated gold nanoparticles. Curr Med Chem. 2017;24(39):4399–4416. doi:10.2174/092986732466617081015491728799495
   PubMed Web of Science ®Google Scholar
• Yang R, An Y, Miao F, Li M, Liu P, Tang Q. Preparation of folic acid-conjugated, doxorubicin-loaded, magnetic bovine serum albumin nanospheres and their antitumor effects in vitro and in vivo. Int J Nanomedicine. 2014;9:4231–4243. doi:10.2147/IJN.S6721025228802
   PubMed Web of Science ®Google Scholar
• Shi Y, Su C, Cui W, et al. Gefitinib loaded folate decorated bovine serum albumin conjugated carboxymethyl-beta-cyclodextrin nanoparticles enhance drug delivery and attenuate autophagy in folate receptor-positive cancer cells. J Nanobiotechnology. 2014;12(1):43. doi:10.1186/s12951-014-0043-725358257
   PubMedGoogle Scholar
• Lee RJ, Low PS. Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis. J Biol Chem. 1994;269(5):3198–3204.8106354
   PubMed Web of Science ®Google Scholar
• Ma N, Liu J, He W, et al. Folic acid-grafted bovine serum albumin decorated graphene oxide: an efficient drug carrier for targeted cancer therapy. J Colloid Interface Sci. 2017;490:598–607. doi:10.1016/j.jcis.2016.11.09727923144
   PubMed Web of Science ®Google Scholar
• Neshastehriz A, Tabei M, Maleki S, Eynali S, Shakeri-Zadeh A. Photothermal therapy using folate conjugated gold nanoparticles enhances the effects of 6MV X-ray on mouth epidermal carcinoma cells. J Photochem Photobiol B. 2017;172:52–60. doi:10.1016/j.jphotobiol.2017.05.01228527427
   PubMed Web of Science ®Google Scholar
• Kim SN, Ha YW, Shin H, Son SH, Wu SJ, Kim YS. Simultaneous quantification of 14 ginsenosides in Panax ginseng C.A. Meyer (Korean red ginseng) by HPLC-ELSD and its application to quality control. J Pharm Biomed Anal. 2007;45(1):164–170. doi:10.1016/j.jpba.2007.05.00117560064
   PubMed Web of Science ®Google Scholar
• Wang L, Li M, Zhang N. Folate-targeted docetaxel-lipid-based-nanosuspensions for active-targeted cancer therapy. Int J Nanomedicine. 2012;7:3281–3294. doi:10.2147/IJN.S3252022802688
   PubMed Web of Science ®Google Scholar
• Gharebaghi F, Dalali N, Ahmadi E, Danafar H. Preparation of wormlike polymeric nanoparticles coated with silica for delivery of methotrexate and evaluation of anticancer activity against MCF7 cells. J Biomater Appl. 2017;31(9):1305–1316. doi:10.1177/088532821769806328447548
   PubMedGoogle Scholar
• Zhang J, Wang Y, Jiang Y, et al. Enhanced cytotoxic and apoptotic potential in hepatic carcinoma cells of chitosan nanoparticles loaded with ginsenoside compound K. Carbohydr Polym. 2018;198:537–545. doi:10.1016/j.carbpol.2018.06.12130093032
   PubMed Web of Science ®Google Scholar
• Mirrahimi M, Hosseini V, Kamrava SK, et al. Selective heat generation in cancer cells using a combination of 808 nm laser irradiation and the folate-conjugated Fe2O3@Au nanocomplex. Artif Cells Nanomed Biotechnol. 2018;46(sup1):241–253. doi:10.1080/21691401.2017.1420072
   PubMed Web of Science ®Google Scholar
• Yang Z, Sun N, Cheng R, et al. pH multistage responsive micellar system with charge-switch and PEG layer detachment for co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells. Biomaterials. 2017;147:53–67. doi:10.1016/j.biomaterials.2017.09.01328930649
   PubMed Web of Science ®Google Scholar
• Yang Z, Sun N, Cheng R, Zhao C, Liu J, Tian Z. Hybrid nanoparticles coated with hyaluronic acid lipoid for targeted co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells. J Mater Chem B. 2017;5(33):6762–6775. doi:10.1039/C7TB01510K
   PubMed Web of Science ®Google Scholar
• Li JM, Chen W, Wang H, et al. Preparation of albumin nanospheres loaded with gemcitabine and their cytotoxicity against BXPC-3 cells in vitro. Acta Pharmacol Sin. 2009;30:1337. doi:10.1038/aps.2009.12519730429
   PubMed Web of Science ®Google Scholar
• Cheng X, Wang X, Cao Z, Yao W, Wang J, Tang R. Folic acid-modified soy protein nanoparticles for enhanced targeting and inhibitory. Mat Sci Eng C. 2017;71:298–307. doi:10.1016/j.msec.2016.10.018
   PubMed Web of Science ®Google Scholar
• Zhao D, Zhao X, Zu Y, et al. Preparation, characterization, and in vitro targeted delivery of folate-decorated paclitaxel-loaded bovine serum albumin nanoparticles. Int J Nanomedicine. 2010;5:669–677.20957218
   PubMed Web of Science ®Google Scholar
• Dubey RD, Alam N, Saneja A, et al. Development and evaluation of folate functionalized albumin nanoparticles for targeted delivery of gemcitabine. Int J Pharm. 2015;492(1):80–91. doi:10.1016/j.ijpharm.2015.07.01226165611
   PubMedGoogle Scholar
• Qi L, Guo Y, Luan J, Zhang D, Zhao Z, Luan Y. Folate-modified bexarotene-loaded bovine serum albumin nanoparticles as a promising tumor-targeting delivery system. J Mater Chem B. 2014;2(47):8361–8371. doi:10.1039/C4TB01102C
   PubMed Web of Science ®Google Scholar
• Singh P, Kim YJ, Singh H, Ahn S, Castro-Aceituno V, Yang DC. In situ preparation of water-soluble ginsenoside Rh2-entrapped bovine serum albumin nanoparticles: in vitro cytocompatibility studies. Int J Nanomedicine. 2017;12:4073–4084. doi:10.2147/IJN.S12515428603419
   PubMed Web of Science ®Google Scholar
• Mathiyalagan R, Subramaniyam S, Kim YJ, Kim Y-C, Yang DC. Ginsenoside compound K-bearing glycol chitosan conjugates: synthesis, physicochemical characterization, and in vitro biological studies. Carbohydr Polym. 2014;112:359–366. doi:10.1016/j.carbpol.2014.05.09825129755
   PubMed Web of Science ®Google Scholar
• Song L, Pan Z, Zhang H, et al. Dually folate/CD44 receptor-targeted self-assembled hyaluronic acid nanoparticles for dual-drug delivery and combination cancer therapy. J Mater Chem B. 2017;5(33):6835–6846. doi:10.1039/C7TB01548H
   PubMed Web of Science ®Google Scholar
• Shakeri-Zadeh A, Shiran M-B, Khoee S, Sharifi AM, Ghaznavi H, Khoei S. A new magnetic nanocapsule containing 5-fluorouracil: in vivo drug release, anti-tumor, and pro-apoptotic effects on CT26 cells allograft model. J Biomater Appl. 2014;29(4):548–556. doi:10.1177/088532821453694024913615
   PubMed Web of Science ®Google Scholar
• Nosrati H, Abbasi R, Charmi J, et al. Folic acid conjugated bovine serum albumin: an efficient smart and tumor targeted biomacromolecule for inhibition folate receptor positive cancer cells. Int J Biol Macromol. 2018;117:1125–1132. doi:10.1016/j.ijbiomac.2018.06.02629885392
   PubMed Web of Science ®Google Scholar
• Salehiabar M, Nosrati H, Javani E, et al. Production of biological nanoparticles from bovine serum albumin as controlled release carrier for curcumin delivery. Int J Biol Macromol. 2018;115:83–89. doi:10.1016/j.ijbiomac.2018.04.04329653171
   PubMed Web of Science ®Google Scholar
• Shen Z, Li Y, Kohama K, Oneill B, Bi J. Improved drug targeting of cancer cells by utilizing actively targetable folic acid-conjugated albumin nanospheres. Pharmacol Res. 2011;63(1):51–58. doi:10.1016/j.phrs.2010.10.01221035550
   PubMed Web of Science ®Google Scholar
• Montazerabadi A, Beik J, Irajirad R, et al. Folate-modified and curcumin-loaded dendritic magnetite nanocarriers for the targeted thermo-chemotherapy of cancer cells. Artif Cells Nanomed Biotechnol. 2019;47(1):330–340. doi:10.1080/21691401.2018.155767030688084
   PubMed Web of Science ®Google Scholar
• Zeinizade E, Tabei M, Shakeri-Zadeh A, et al. Selective apoptosis induction in cancer cells using folate-conjugated gold nanoparticles and controlling the laser irradiation conditions. Artif Cells Nanomed Biotechnol. 2018;46(sup1):1026–1038. doi:10.1080/21691401.2018.144311629486617
   PubMed Web of Science ®Google Scholar
• Ghaznavi H, Hosseini-Nami S, Kamrava SK, et al. Folic acid conjugated PEG coated gold–iron oxide core–shell nanocomplex as a potential agent for targeted photothermal therapy of cancer. Artif Cells Nanomed Biotechnol. 2018;46(8):1594–1604. doi:10.1080/21691401.2017.138438428994325
   PubMed Web of Science ®Google Scholar
• Wu Q, Deng J, Fan D, et al. Ginsenoside Rh4 induces apoptosis and autophagic cell death through activation of the ROS/JNK/p53 pathway in colorectal cancer cells. Biochem Pharmacol. 2018;148:64–74. doi:10.1016/j.bcp.2017.12.00429225132
   PubMed Web of Science ®Google Scholar