Nd₂O₃ Nanoparticles Induce Toxicity and Cardiac/Cerebrovascular Abnormality in Zebrafish Embryos via the Apoptosis Pathway

References

• Liu C, Hou Y, Gao M. Are rare-earth nanoparticles suitable for in vivo applications? Adv Mat. 2014;26(40):6922–6932. doi:10.1002/adma.v26.40
   PubMed Web of Science ®Google Scholar
• Liang XJ, Meng H, Wang Y, et al. Metallofullerene nanoparticles circumvent tumor resistance to cisplatin by reactivating endocytosis. Proc Natl Acad Sci U S A. 2010;107(16):7449–7454. doi:10.1073/pnas.090970710720368438
   PubMed Web of Science ®Google Scholar
• Turra C. Sustainability of rare earth elements chain: from production to food - a review. Int J Environ Health Res. 2018;28(1):23–42. doi:10.1080/09603123.2017.141530729241344
   PubMed Web of Science ®Google Scholar
• Franchi LP, Manshian BB, de Souza TA, et al. Cyto- and genotoxic effects of metallic nanoparticles in untransformed human fibroblast. Toxicol in Vitro. 2015;29(7):1319–1331. doi:10.1016/j.tiv.2015.05.01026028148
   PubMed Web of Science ®Google Scholar
• Cui J, Zhang Z, Bai W, et al. Effects of rare earth elements La and Yb on the morphological and functional development of zebrafish embryos. J Environ Sci. 2012;24(2):209–213. doi:10.1016/S1001-0742(11)60755-9
   Google Scholar
• Kim YS, Lim CH, Shin SH, Kim JC. Twenty-eight-day repeated inhalation toxicity study of nano-sized neodymium oxide in male sprague-dawley rats. Toxicol Res. 2017;33(3):239–253. doi:10.5487/TR.2017.33.3.23928744356
   PubMed Web of Science ®Google Scholar
• Mesquita B, Lopes I, Silva S, et al. Gold nanorods induce early embryonic developmental delay and lethality in zebrafish (Danio rerio). ‎J Toxicol Environ Health A. 2017;80(13–15):672–687. doi:10.1080/15287394.2017.133159728696918
   PubMed Web of Science ®Google Scholar
• He A, Kwatra SG, Zampella JG, Loss MJ. Nephrogenic systemic fibrosis: fibrotic plaques and contracture following exposure to gadolinium-based contrast media. BMJ Case Rep. 2016;2016. doi:10.1136/bcr-2015-212769
   Google Scholar
• Pagano G, Aliberti F, Guida M, et al. Rare earth elements in human and animal health: state of art and research priorities. Environ Res. 2015;142:215–220. doi:10.1016/j.envres.2015.06.03926164116
   PubMed Web of Science ®Google Scholar
• Farouk M, Abd El-Maboud A, Ibrahim M, Ratep A, Kashif I. Optical properties of Lead bismuth borate glasses doped with neodymium oxide. Spectrochim Acta a Mol Biomol Spectrosc. 2015;149:338–342. doi:10.1016/j.saa.2015.04.07025965518
   PubMed Web of Science ®Google Scholar
• Hill AJ, Teraoka H, Heideman W, Peterson RE. Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol Sci. 2005;86(1):6–19. doi:10.1093/toxsci/kfi11015703261
   PubMed Web of Science ®Google Scholar
• Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Stages of embryonic development of the zebrafish. Dev Dyn. 1995;203(3):253–310. doi:10.1002/aja.10020303028589427
   PubMed Web of Science ®Google Scholar
• Jia XE, Ma K, Xu T, et al. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Res. 2015;25(8):946–962. doi:10.1038/cr.2015.8126138676
   PubMed Web of Science ®Google Scholar
• Lee KJ, Browning LM, Nallathamby PD, Xu XH. Study of charge-dependent transport and toxicity of peptide-functionalized silver nanoparticles using zebrafish embryos and single nanoparticle plasmonic spectroscopy. Chem Res Toxicol. 2013;26(6):904–917. doi:10.1021/tx400087d23621491
   PubMed Web of Science ®Google Scholar
• Browning LM, Lee KJ, Huang T, Nallathamby PD, Lowman JE, Xu XH. Random walk of single gold nanoparticles in zebrafish embryos leading to stochastic toxic effects on embryonic developments. Nanoscale. 2009;1(1):138–152. doi:10.1039/b9nr00053d20644873
   PubMed Web of Science ®Google Scholar
• Martino C, Costa C, Roccheri MC, Koop D, Scudiero R, Byrne M. Gadolinium perturbs expression of skeletogenic genes, calcium uptake and larval development in phylogenetically distant sea urchin species. Aquat Toxicol. 2018;194:57–66. doi:10.1016/j.aquatox.2017.11.00429156215
   PubMed Web of Science ®Google Scholar
• Martino C, Chiarelli R, Bosco L, Roccheri MC. Induction of skeletal abnormalities and autophagy in Paracentrotus lividus sea urchin embryos exposed to gadolinium. Mar Environ Res. 2017;130:12–20. doi:10.1016/j.marenvres.2017.07.00728712826
   PubMed Web of Science ®Google Scholar
• Welsh DG, Nelson MT, Eckman DM, Brayden JE. Swelling-activated cation channels mediate depolarization of rat cerebrovascular smooth muscle by hyposmolarity and intravascular pressure. J Physiol. 2000;527 Pt 1:139–148. doi:10.1111/tjp.2000.527.issue-110944177
   PubMed Web of Science ®Google Scholar
• Akre BT, Dunkel JA, Hustvedt SO, Refsum H. Acute cardiotoxicity of gadolinium-based contrast media: findings in the isolated rat heart. Acad Radiol. 1997;4(4):283–291. doi:10.1016/S1076-6332(97)80030-X9110026
   PubMed Web of Science ®Google Scholar
• Saghiri MA, Orangi J, Asatourian A, Sorenson CM, Sheibani N. Functional role of inorganic trace elements in angiogenesis part III: (Ti, Li, Ce, As, Hg, Va, Nb and Pb). Crit Rev Oncol Hematol. 2016;98:290–301. doi:10.1016/j.critrevonc.2015.10.00426638864
   PubMed Web of Science ®Google Scholar
• Giri S, Karakoti A, Graham RP, et al. Nanoceria: a rare-earth nanoparticle as a novel anti-angiogenic therapeutic agent in ovarian cancer. PLoS One. 2013;8(1):e54578. doi:10.1371/journal.pone.005457823382918
   PubMed Web of Science ®Google Scholar
• Zheng Y, Wu Z, Yi F, et al. By activating Akt/eNOS bilobalide B inhibits autophagy and promotes angiogenesis following focal cerebral ischemia reperfusion. Cell Physiol Biochem. 2018;47(2):604–616. doi:10.1159/00049001629794436
   PubMedGoogle Scholar
• Du J, Teng RJ, Guan T, et al. Role of autophagy in angiogenesis in aortic endothelial cells. Am J Physiol Cell Physiol. 2012;302(2):C383–C391. doi:10.1152/ajpcell.00164.201122031599
   PubMed Web of Science ®Google Scholar
• Carmeliet P, Tessier-Lavigne M. Common mechanisms of nerve and blood vessel wiring. Nature. 2005;436(7048):193–200. doi:10.1038/nature0387516015319
   PubMed Web of Science ®Google Scholar
• Eichmann A, Le Noble F, Autiero M, Carmeliet P. Guidance of vascular and neural network formation. Curr Opin Neurobiol. 2005;15(1):108–115. doi:10.1016/j.conb.2005.01.00815721752
   PubMed Web of Science ®Google Scholar
• Mikhailova MM, Panteleyev AA Jr., Paltsev MA, Panteleyev AA. Spinal cord tissue affects sprouting from aortic fragments in ex vivo co-culture. Cell Biol Int. 2019. doi:10.1002/cbin.11112
   PubMed Web of Science ®Google Scholar
• Huang LH, Yang H, Su X, Gao YR, Xue HN, Wang SH. Neodymium oxide induces cytotoxicity and activates NF-kappaB and Caspase-3 in NR8383 cells. Biomed Environ Sci. 2017;30(1):75–78. doi:10.3967/bes2017.01028245903
   PubMed Web of Science ®Google Scholar
• Lu VM, Crawshay-Williams F, White B, Elliot A, Hill MA, Townley HE. Cytotoxicity, dose-enhancement and radiosensitization of glioblastoma cells with rare earth nanoparticles. Artif Cells Nanomed Biotechnol. 2019;47(1):132–143. doi:10.1080/21691401.2018.154456430663430
   PubMed Web of Science ®Google Scholar
• Zhang Y, Yu C, Huang G, Wang C, Wen L. Nano rare-earth oxides induced size-dependent vacuolization: an independent pathway from autophagy. Int J Nanomedicine. 2010;5:601–609. doi:10.2147/IJN.S1151320856835
   PubMed Web of Science ®Google Scholar
• Yu L, Lu Y, Man N, Yu SH, Wen LP. Rare earth oxide nanocrystals induce autophagy in HeLa cells. Small. 2009;5(24):2784–2787. doi:10.1002/smll.20090171419885892
   PubMed Web of Science ®Google Scholar
• Yang T, Wu T, Lv L, et al. Ceria oxide nanoparticles an ideal carrier given little stress to cells and rats. J Nanosci Nanotechnol. 2018;18(6):3865–3869. doi:10.1166/jnn.2018.1501829442720
   PubMed Web of Science ®Google Scholar
• Hussain S, Al-Nsour F, Rice AB, et al. Cerium dioxide nanoparticles induce apoptosis and autophagy in human peripheral blood monocytes. ACS Nano. 2012;6(7):5820–5829. doi:10.1021/nn302235u22717232
   PubMed Web of Science ®Google Scholar
• Alarifi S, Ali H, Alkahtani S, Alessia MS. Regulation of apoptosis through bcl-2/Bax proteins expression and DNA damage by nano-sized gadolinium oxide. Int J Nanomedicine. 2017;12:4541–4551. doi:10.2147/IJN.S13932628684914
   PubMed Web of Science ®Google Scholar
• Hosseini A, Sharifi AM, Abdollahi M, et al. Cerium and yttrium oxide nanoparticles against lead-induced oxidative stress and apoptosis in rat hippocampus. Biol Trace Elem Res. 2015;164(1):80–89. doi:10.1007/s12011-014-0197-z25516117
   PubMed Web of Science ®Google Scholar