Antigen-Conjugated Silica Solid Sphere as Nanovaccine for Cancer Immunotherapy

References

• Metelmann H-R, Seebauer C, Miller V, et al. Clinical experience with cold plasma in the treatment of locally advanced head and neck cancer. Clin Plasma Med. 2018;9:6–13. doi:10.1016/j.cpme.2017.09.001
   Web of Science ®Google Scholar
• Mao Q, Li L, Zhang C, Sun Y, Liu S, Cui S. Clinical effects of immunotherapy of DC-CIK combined with chemotherapy in treating patients with metastatic breast cancer. Pak J Pharm Sci. 2015;28:1055–1058.26051718
   PubMed Web of Science ®Google Scholar
• Kelly PN. The cancer immunotherapy revolution. Science. 2018;359(6382):1344–1345. doi:10.1126/science.359.6382.134429567702
   PubMed Web of Science ®Google Scholar
• Couzin-Frankel J. Cancer immunotherapy. Science. 2013;342(6165):1432–1433. doi:10.1126/science.342.6165.143224357284
   PubMed Web of Science ®Google Scholar
• Cui J, De Rose R, Best JP, et al. Mechanically tunable, self-adjuvanting nanoengineered polypeptide particles. Adv Mater. 2013;25(25):3468–3472. doi:10.1002/adma.20130098123661596
   PubMed Web of Science ®Google Scholar
• Schietinger A, Philip M, Krisnawan VE, et al. Tumor-specific T cell dysfunction is a dynamic antigen-driven differentiation program initiated early during tumorigenesis. Immunity. 2016;45(2):389–401. doi:10.1016/j.immuni.2016.07.01127521269
   PubMed Web of Science ®Google Scholar
• Santos PM, Butterfield LH. Dendritic cell–based cancer vaccines. J Immunol. 2018;200(2):443–449. doi:10.4049/jimmunol.170102429311386
   PubMed Web of Science ®Google Scholar
• DJ I, MC H, K R, T T. Synthetic nanoparticles for vaccines and immunotherapy. Chem Rev. 2015;115(19):11109–11146. doi:10.1021/acs.chemrev.5b0010926154342
   PubMed Web of Science ®Google Scholar
• Luo M, Wang H, Wang Z, et al. A STING-activating nanovaccine for cancer immunotherapy. Nat Nanotechnol. 2017;12(7):648–654. doi:10.1038/nnano.2017.5228436963
   PubMed Web of Science ®Google Scholar
• Voron T, Colussi O, Marcheteau E, et al. VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors. J Exp Med. 2015;212(2):139–148. doi:10.1084/jem.2014055925601652
   PubMed Web of Science ®Google Scholar
• Wallin JJ, Bendell JC, Funke R, et al. Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma. Nat Commun. 2016;7:12624. doi:10.1038/ncomms1262427571927
   PubMed Web of Science ®Google Scholar
• Silva A, Soema P, Slütter B, Ossendorp F, Jiskoot W. PLGA particulate delivery systems for subunit vaccines: linking particle properties to immunogenicity. Hum Vaccines Immunother. 2016;12(4):1056–1069. doi:10.1080/21645515.2015.1117714
   PubMed Web of Science ®Google Scholar
• Gu L. Tailored silica nanomaterials for immunotherapy. ACS Cent Sci. 2018;4(5):527–529. doi:10.1021/acscentsci.8b0018129805996
   PubMed Web of Science ®Google Scholar
• Tang F, Li L, Chen D. Mesoporous silica nanoparticles: synthesis, biocompatibility and drug delivery. Adv Mater. 2012;24(12):1504–1534. doi:10.1002/adma.20110476322378538
   PubMed Web of Science ®Google Scholar
• Li T, Shi S, Goel S, et al. Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer. Acta Biomater. 2019;89:1–13. doi:10.1016/j.actbio.2019.02.03130797106
   PubMed Web of Science ®Google Scholar
• Li W, Liu Z, Fontana F, et al. Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy. Adv Mater. 2018;30(24):1703740. doi:10.1002/adma.201703740
   Web of Science ®Google Scholar
• Hudson SP, Padera RF, Langer R, Kohane DS. The biocompatibility of mesoporous silicates. Biomaterials. 2008;29(30):4045–4055. doi:10.1016/j.biomaterials.2008.07.00718675454
   PubMed Web of Science ®Google Scholar
• Wang X, Chen Z, Zhang C, et al. A generic coordination assembly-enabled nanocoating of individual tumor cells for personalized immunotherapy. Adv Healthc Mater. 2019;18:1900474. doi:10.1002/adhm.201900474
   Google Scholar
• Wang X, Cao F, Yan M, et al. Alum-functionalized graphene oxide nanocomplexes for effective anticancer vaccination. Acta Biomater. 2019;83:390–399. doi:10.1016/j.actbio.2018.11.02330448435
   PubMed Web of Science ®Google Scholar
• Stöber W, Fink A, Bohn E. Controlled growth of monodisperse silica spheres in the micron size range. J Colloid Interface Sci. 1968;26(1):62–69. doi:10.1016/0021-9797(68)90272-5
   Web of Science ®Google Scholar
• Zhang W, Wang L, Liu Y, et al. Immune responses to vaccines involving a combined antigen–nanoparticle mixture and nanoparticle-encapsulated antigen formulation. Biomaterials. 2014;35(23):6086–6097. doi:10.1016/j.biomaterials.2014.04.02224780166
   PubMed Web of Science ®Google Scholar
• Pei M, Liang J, Zhang C, et al. Chitosan/calcium phosphates nanosheet as a vaccine carrier for effective cross-presentation of exogenous antigens. Carbohydr Polym. 2019;224:115172. doi:10.1016/j.carbpol.2019.11517231472830
   PubMed Web of Science ®Google Scholar
• Yan S, Rolfe BE, Zhang B, Mohammed YH, Gu W, Xu ZP. Polarized immune responses modulated by layered double hydroxides nanoparticle conjugated with CpG. Biomaterials. 2014;35(35):9508–9516. doi:10.1016/j.biomaterials.2014.07.05525145853
   PubMed Web of Science ®Google Scholar
• Gao Y, Yang C, Liu X, Ma R, Kong D, Shi L. A multifunctional nanocarrier based on nanogated mesoporous silica for enhanced tumor-specific uptake and intracellular delivery. Macromol Biosci. 2012;12(2):251–259. doi:10.1002/mabi.20110020822076739
   PubMed Web of Science ®Google Scholar
• Xu J, Wang H, Xu L, et al. Nanovaccine based on a protein-delivering dendrimer for effective antigen cross-presentation and cancer immunotherapy. Biomaterials. 2019;207:1–9. doi:10.1016/j.biomaterials.2019.03.03730947117
   PubMed Web of Science ®Google Scholar
• Sarkar K, Kruhlak MJ, Erlandsen SL, Shaw S. Selective inhibition by rottlerin of macropinocytosis in monocyte-derived dendritic cells. Immunology. 2005;116(4):513–524. doi:10.1111/j.1365-2567.2005.02253.x16313365
   PubMed Web of Science ®Google Scholar
• Wang LH, Rothberg KG, Anderson RG. Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol. 1993;123(5):1107–1117. doi:10.1083/jcb.123.5.11078245121
   PubMed Web of Science ®Google Scholar
• Casaravilla C, Pittini Á, Rückerl D, et al. Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosus. Infect Immun. 2014;82(8):3164–3176. doi:10.1128/IAI.01959-1424842926
   PubMed Web of Science ®Google Scholar
• Schnitzer JE, Oh P, Pinney E, Allard J. Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J Cell Biol. 1994;127(5):1217–1232. doi:10.1083/jcb.127.5.12177525606
   PubMed Web of Science ®Google Scholar
• Latz E, Schoenemeyer A, Visintin A, et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol. 2004;5(2):190–198. doi:10.1038/ni102814716310
   PubMed Web of Science ®Google Scholar
• Hjortø GM, Larsen O, Steen A, et al. Differential CCR7 targeting in dendritic cells by three naturally occurring CC-chemokines. Front Immunol. 2016;7:568. doi:10.3389/fimmu.2016.0056828018341
   PubMed Web of Science ®Google Scholar
• Gerlach C, Moseman EA, Loughhead SM, et al. The chemokine receptor CX3CR1 defines three antigen-experienced CD8 T cell subsets with distinct roles in immune surveillance and homeostasis. Immunity. 2016;45(6):1270–1284. doi:10.1016/j.immuni.2016.10.01827939671
   PubMed Web of Science ®Google Scholar
• Lutz MB, Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol. 2002;23(9):445–449. doi:10.1016/S1471-4906(02)02281-012200066
   PubMed Web of Science ®Google Scholar
• Tugues S, Burkhard SH, Ohs I, et al. New insights into IL-12-mediated tumor suppression. Cell Death Differ. 2015;22(2):237–246. doi:10.1038/cdd.2014.13425190142
   PubMed Web of Science ®Google Scholar
• Wang L, Zhao Y, Liu Y, et al. IFN-γ and TNF-α synergistically induce mesenchymal stem cell impairment and tumorigenesis via NFκB signaling. Stem Cells. 2013;31(7):1383–1395. doi:10.1002/stem.138823553791
   PubMed Web of Science ®Google Scholar
• Morel PA, Butterfield LH. Dendritic cell control of immune responses. Front Immunol. 2015;6(2–3):42. doi:10.3389/fimmu.2015.0004225699058
   PubMedGoogle Scholar