154
Views
9
CrossRef citations to date
0
Altmetric
Original Research

Tuftsin-Bearing Liposomes Co-Encapsulated with Doxorubicin and Curcumin Efficiently Inhibit EAC Tumor Growth in Mice

, , ORCID Icon, & ORCID Icon
Pages 10547-10559 | Published online: 31 Dec 2020

References

  • Glasgow MDK, Chougule. MB. Recent developments in active tumor targeted multifunctional nanoparticles for combination chemotherapy in cancer treatment and imaging. J Biomed Nanotechnol. 2015;11(11):1859–1898. doi:10.1166/jbn.2015.214526554150
  • Pastorino F, Brignole C, Paolo DD, et al. Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy. Cancer Res. 2006;66(20):10073–10082. doi:10.1158/0008-5472.CAN-06-211717047071
  • Barui S, Saha S, Mondal G, Haseena S, Chaudhuri A. Simultaneous Delivery of doxorubicin and curcumin encapsulated in liposomes of pegylated RGDK-lipopeptide to tumor vasculature. Biomaterials. 2014;35(5):1643–1656. doi:10.1016/j.biomaterials.2013.10.07424239109
  • Sengupta S, Eavarone D, Capila I, et al. Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system. Nature. 2005;436(7050):568–572. doi:10.1038/nature0379416049491
  • Agarwal A, Kandpal H, Gupta HP, Singh NB, Gupta CM. Tuftsin-bearing liposomes as rifampin vehicles in treatment of tuberculosis in mice. Antimicrob Agents Chemother. 1994;38(3):588–593.8203859
  • Owais M, Ahmed I, Krishnakumar B, Jain RK, Bachhawat BK, Gupta CM. Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis. FEBS Lett. 1993;326(1–3):56–58. doi:10.1016/0014-5793(93)81760-W8325389
  • Agrawal AK, Gupta CM. Tuftsin-bearing liposomes in treatment of macrophage-based infections. Adv Drug Deliv Rev. 2000;41(2):135–146. doi:10.1016/S0169-409X(99)00061-710699310
  • Khan A, Khan AA, Varun Dwivedi MG, Ahmad SH, Owais M. Tuftsin augments antitumor efficacy of liposomized etoposide against fibrosarcoma in Swiss Albino Mice. Mol Med. 2007;13(5–6):266–276. doi:10.2119/2007-00018.Khan17622310
  • Zou B, Xia S, Xiaohui D, et al. Treatment effect of tuftsin and antigen peptide combined with immune cells on colorectal cancer. Med Sci Monit. 2019;25:5465–5472.31333222
  • Nissen JC, Selwood DL, Tsirka SE. Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway. J Neurochem. 2013;127(3):394–402. doi:10.1111/jnc.1240424033337
  • Siebert A, Gensicka-Kowalewska M, Cholewinski G, Dzierzbicka K. Tuftsin – properties and analogs. Curr Med Chem. 2017;24(34):3711–3727. doi:10.2174/092986732466617072514082628745220
  • Mohammad N, Singh SV, Malvi P, et al. Strategy to enhance efficacy of doxorubicin in solid tumor cells by methyl-β-cyclodextrin: involvement of p53 and fas receptor ligand complex. Sci Rep. 2015;5(1):11853. doi:10.1038/srep1185326149967
  • Pugazhendhi A, Edison TN, Velmurugan BK, Jacob JA, Karuppusamy I. Toxicity of Doxorubicin (Dox) to different experimental organ systems. Life Sci. 2018;200(May):26–30. doi:10.1016/j.lfs.2018.03.02329534993
  • Zhang Q, Wei D, Liu J. In vivo reversal of doxorubicin resistance by (-)-epigallocatechin gallate in a solid human carcinoma xenograft. Cancer Lett. 2004;208(2):179–186.15142676
  • Yu LL, Wu JG, Dai N, Yu HG, Si JΜ. Curcumin reverses chemoresistance of human gastric cancer cells by downregulating the NF-κB transcription factor. Oncol Rep. 2011;26(5):1197–1203.21811763
  • Ganta S, Amiji M. Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol Pharm. 2009;6(3):928–939. doi:10.1021/mp800240j19278222
  • Duan J, Mansour HM, Zhang Y, et al. Reversion of multidrug resistance by co-encapsulation of doxorubicin and curcumin in chitosan/poly(butyl cyanoacrylate) nanoparticles. Int J Pharm. 2012;426(1–2):193–201. doi:10.1016/j.ijpharm.2012.01.02022274587
  • Sercombe L, Veerati T, Moheimani F, Wu SY, Sood AK, Hua S. Advances and challenges of liposome assisted drug delivery. Front Pharmacol. 2015;6(December):286. doi:10.3389/fphar.2015.0028626648870
  • Gupta CM, Haq W. Tuftsin-bearing liposomes as antibiotic carriers in treatment of macrophage infections. Methods Enzymol. 2005;391:291–304.15721387
  • Jiang T, Zhang Z, Zhang Y, et al. Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery. Biomaterials. 2012;33(36):9246–9258. doi:10.1016/j.biomaterials.2012.09.02723031530
  • Murugesan K, Koroth J, Srinivasan PP, et al. Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models. Int J Nanomed. 2019;14:5257–5270. doi:10.2147/IJN.S202404
  • Misra R, Sahoo SK. Coformulation of doxorubicin and curcumin in poly(D,L-lactide-co-glycolide) nanoparticles suppresses the development of multidrug resistance in K562 cells. Mol Pharm. 2011;8(3):852–866. doi:10.1021/mp100455h21480667
  • Limtrakul P, Chearwae W, Shukla S, Phisalphong C, Ambudkar SV. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. Mol Cell Biochem. 2007;296(1–2):85–95. doi:10.1007/s11010-006-9302-816960658
  • Chearwae W, Chung-Pu W, Chu H-Y, Randall Lee T, Ambudkar SV, Limtrakul P. Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1). Cancer Chemother Pharmacol. 2006;57(3):376–388.16021489
  • Pramanik D, Campbell NR, Das S, et al. A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy. Oncotarget. 2012;3(6):640–650. doi:10.18632/oncotarget.54322791660
  • Bulboacă AE, Boarescu PM, Bolboacă SD, et al. Comparative effect of curcumin versus liposomal curcumin on systemic pro-inflammatory cytokines profile, MCP-1 and RANTES in experimental diabetes mellitus. Int J Nano. 2019;14:8961–8972.
  • Bulboaca AE, Boarescu P-M, Porfire AS, et al. The effect of nano-epigallocatechin-gallate on oxidative stress and matrix metalloproteinases in experimental diabetes mellitus. Antioxidants (Basel, Switzerland). 2020;9:2.
  • Nishioka K, Amoscato AA, Babcock GF. Tuftsin: a hormone-like tetrapeptide with antimicrobial and antitumor activities. Life Sci. 1981;28(10):1081–1090. doi:10.1016/0024-3205(81)90684-66262587
  • Nishioka K, Babcock GF, Phillips JH, Banks RA, Amoscato AA. In vivo and in vitro antitumor activities of tuftsin. Ann N Y Acad Sci. 1983;419(1 Antineoplasti):234–241. doi:10.1111/j.1749-6632.1983.tb37109.x6324636
  • Nishioka K, Babcock GF, Phillips JH, Noyes RD. Antitumor effect of tuftsin. Mol Cell Biochem. 1981;41(December):13–18. doi:10.1007/BF002252936895773
  • Florentin I, Bruley-Rosset M, Kiger N, et al. In vivo immunostimulation by tuftsin. Cancer Immunol Immunother. 1978;5(3):211–216. doi:10.1007/BF00199631
  • Zhivotovsky B, Orrenius S. Defects in the apoptotic machinery of cancer cells: role in drug resistance. Semin Cancer Biol. 2003;13(2):125–134. doi:10.1016/S1044-579X(02)00130-X12654256
  • Reed JC. Apoptosis-regulating proteins as targets for drug discovery. Trends Mol Med. 2001;7(7):314–319. doi:10.1016/S1471-4914(01)02026-311425640
  • Brady HJM, Gil-Gómez G. Molecules in focus bax. The pro-apoptotic Bcl-2 family member, bax. Int J Biochem Cell Biol. 1998;30(6):647–650. doi:10.1016/S1357-2725(98)00006-59695020
  • Ryan KM, Phillips AC, Vousden KH. Regulation and function of the p53 tumor suppressor protein. Curr Opin Cell Biol. 2001;13(3):332–337. doi:10.1016/S0955-0674(00)00216-711343904
  • Basu A, Haldar S. The relationship between BcI2, bax and p53: consequences for cell cycle progression and cell death. Mol Hum Reprod. 1998;4(12):1099–1109. doi:10.1093/molehr/4.12.10999872359
  • Schendel SL. Characterization of BC1-2, BC1-XL, and bax pore formation and their role in apoptosis regulation. 1999. doi:10.21236/ada383308
  • Khan AA, Alanazi AM, Jabeen M, Hassan I, Bhat MA. Targeted nano-delivery of novel omega-3 conjugate against hepatocellular carcinoma: regulating COX-2/bcl-2 expression in an animal model. Biomed Pharmacother. 2016;81(July):394–401. doi:10.1016/j.biopha.2016.04.03327261618
  • Khan MA, Owais M. Toxicity, stability and pharmacokinetics of amphotericin b in immunomodulator tuftsin-bearing liposomes in a murine model. J Antimicrob Chemother. 2006;58(1):125–132. doi:10.1093/jac/dkl17716709592