A Novel Para-Amino Salicylic Acid Magnesium Layered Hydroxide Nanocomposite Anti-Tuberculosis Drug Delivery System with Enhanced in vitro Therapeutic and Anti-Inflammatory Properties

References

• World Health Organization. Global Tuberculosis Report 2020. Geneva: World Health Organization; 2020.
   Google Scholar
• Hafkin J, Hittel N, Martin A, Gupta R. Early outcomes in MDR-TB and XDR-TB patients treated with delamanid under compassionate use. Eur Respir J. 2017;50(1):1700311. doi:10.1183/13993003.00311-2017
   PubMedGoogle Scholar
• Press W. Treatment of Tuberculosis Guidelines. 4th ed. WHO/HTM/TB/2009.420. 20 Avenue Appia, 1211 Geneva 27, Switzerland: World Health Organization; 2010.
   Google Scholar
• Liu CH, Liu H, Ge B. Innate immunity in tuberculosis: host defense vs pathogen evasion. Cell Mol Immunol. 2017;14(12):963–975. doi:10.1038/cmi.2017.88
   PubMed Web of Science ®Google Scholar
• Baguma R, Mbandi SK, Rodo MJ, et al. Inflammatory determinants of differential tuberculosis risk in pre-adolescent children and young adults. Front Immunol. 2021;12:639965. doi:10.3389/fimmu.2021.639965
   PubMedGoogle Scholar
• Hayford FEA, Dolman RC, Blaauw R, et al. The effects of anti-inflammatory agents as host-directed adjunct treatment of tuberculosis in humans: a systematic review and meta-analysis. Respir Res. 2020;21(1):223. doi:10.1186/s12931-020-01488-9
   PubMedGoogle Scholar
• Toossi Z. The inflammatory response in Mycobacterium tuberculosis infection. Arch Immunol Ther Exp (Warsz). 2000;48(6):513–519.
   PubMedGoogle Scholar
• Tomić M, Micov A, Pecikoza U, Stepanović-Petrović R. Chapter 1 - clinical uses of nonsteroidal anti-inflammatory drugs (NSAIDs) and potential benefits of NSAIDs modified-release preparations. In: Čalija B, editor. Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs. Boston: Academic Press; 2017:1–29.
   Google Scholar
• Krajišnik D, Čalija B, Cekić N. Chapter 2 - polymeric microparticles and inorganic micro/nanoparticulate drug carriers: an overview and pharmaceutical application. In: Čalija B, editor. Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs. Boston: Academic Press; 2017:31–67.
   Google Scholar
• Saifullah B. Inorganic nanolayers: structure, preparation, and biomedical applications. Int J Nanomedicine. 2015;10:24.
   Google Scholar
• Yan L, Gonca S, Zhu G, Zhang W, Chen X. Layered double hydroxide nanostructures and nanocomposites for biomedical applications. J Mater Chem B. 2019;7(37):5583–5601. doi:10.1039/C9TB01312A
   PubMedGoogle Scholar
• Wijitwongwan RP, Intasa-ard S, Ogawa M. Preparation of layered double hydroxides toward precisely designed hierarchical organization. ChemEngineering. 2019;3(3):22. doi:10.3390/chemengineering3030068
   Google Scholar
• Laipan M, Yu J, Zhu R, et al. Functionalized layered double hydroxides for innovative applications. Mater Horiz. 2020;7(3):715–745.
   Google Scholar
• Liu JC, Qi B, Song YF. Engineering polyoxometalate-intercalated layered double hydroxides for catalytic applications. Dalton Trans. 2020;49(13):3934–3941.
   Google Scholar
• Bullo Saifullah PA. Development of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide. Int J Nanomedicine. 2014;9:14.
   Google Scholar
• Yazdani P, Mansouri E, Eyvazi S, et al. Layered double hydroxide nanoparticles as an appealing nanoparticle in gene/plasmid and drug delivery system in C2C12 myoblast cells. Artif Cells, Nanomed Biotechnol. 2019;47(1):436–442. doi:10.1080/21691401.2018.1559182
   PubMed Web of Science ®Google Scholar
• Abo El-Reesh GY, Farghali AA, Taha M, Mahmoud RK. Novel synthesis of Ni/Fe layered double hydroxides using urea and glycerol and their enhanced adsorption behavior for Cr(VI) removal. Sci Rep. 2020;10(1):587. doi:10.1038/s41598-020-57519-4
   PubMedGoogle Scholar
• Bohn T. Magnesium Absorption in Humans. Germany: University Frankfurt; 2003.
   Google Scholar
• Wester PO, Dyckner T. The importance of the magnesium ion. Magnesium deficiency symptomatology and occurrence. Acta Med Scand Suppl. 1998;661:2.
   Google Scholar
• Brady H. Magnesium: the forgotten cation. Ir Med J. 1982;80:4.
   Google Scholar
• Severino P, Netti L, Mariani MV, Maraone A. Prevention of cardiovascular disease: screening for magnesium deficiency. Cardiol Res Pract. 2019;2019:10. doi:10.1155/2019/4874921
   Google Scholar
• Figueiredo MP, Cunha VRR, Leroux F, et al. Iron-based layered double hydroxide implants: potential drug delivery carriers with tissue biointegration promotion and blood microcirculation preservation. ACS Omega. 2018;3(12):18263–18274. doi:10.1021/acsomega.8b02532
   Google Scholar
• Mansouri E, Tarhriz V, Yousefi V, Dilmaghani A. Intercalation and release of an anti-inflammatory drug into designed three-dimensionally layered double hydroxide nanostructure via calcination–reconstruction route. Adsorption. 2020;26(6):835–842. doi:10.1007/s10450-020-00217-4
   Web of Science ®Google Scholar
• Rabiee N, Bagherzadeh M, Ghadiri AM, Salehi G, Fatahi Y, Dinarvand R. ZnAl nano layered double hydroxides for dual functional CRISPR/Cas9 delivery and enhanced green fluorescence protein biosensor. Sci Rep. 2020;10(1):20672. doi:10.1038/s41598-020-77809-1
   PubMedGoogle Scholar
• Yousefi V, Tarhriz V, Eyvazi S, Dilmaghani A. Synthesis and application of magnetic@layered double hydroxide as an anti-inflammatory drugs nanocarrier. J Nanobiotechnology. 2020;18(1):155. doi:10.1186/s12951-020-00718-y
   PubMedGoogle Scholar
• Saifullah B, Arulselvan P, El Zowalaty ME, et al. Development of a highly biocompatible antituberculosis nanodelivery formulation based on para-aminosalicylic acid—zinc layered hydroxide nanocomposites. Sci World J. 2014;2014:401460. doi:10.1155/2014/401460
   Google Scholar
• Saifullah B, Hussein MZ, Hussein-Al-Ali SH, Arulselvan P, Fakurazi S. Antituberculosis nanodelivery system with controlled-release properties based on para-amino salicylate-zinc aluminum-layered double-hydroxide nanocomposites. Drug Des Devel Ther. 2013;7:1365–1375.
   PubMed Web of Science ®Google Scholar
• Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PWF, Kiel DP. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr. 1999;69(4):727–736. doi:10.1093/ajcn/69.4.727
   PubMed Web of Science ®Google Scholar
• Cavani F, Trifirò F, Vaccari A. Hydrotalcite-type anionic clays: preparation, properties and applications. Catal Today. 1991;11(2):173–301. doi:10.1016/0920-5861(91)80068-K
   Web of Science ®Google Scholar
• Rives V. Layered Double Hydroxides: Present and Future. Nova Science Pub Inc; 2001.
   Google Scholar
• Salak ANV, Lukienko DEL, Shapovalov IM, et al. High-power ultrasonic synthesis and magnetic-field-assisted arrangement of nanosized crystallites of cobalt-containing layered double hydroxides. ChemEngineering MDPI. 2019;3(3):62.
   Google Scholar
• Saifullah B, Hussein MZ. Inorganic nanolayers: structure, preparation, and biomedical applications. Int J Nanomedicine. 2015;10:5609–5633.
   PubMed Web of Science ®Google Scholar
• Labille JGA, Bonasera A, Prestopino G. Layered double hydroxides: a toolbox for chemistry and biology. Crystals. 2019;9(7):361. doi:10.3390/cryst9070361
   Google Scholar
• Cao Z, Li B, Sun L, Li L, Xu ZP, Gu Z. Targeted drug delivery: 2D layered double hydroxide nanoparticles: recent progress toward preclinical/clinical nanomedicine (small methods 2/2020). Small Methods. 2020;4(2):2070008. doi:10.1002/smtd.202070008
   Google Scholar
• Boman G. Serum concentration and half-life of rifampicin after simultaneous oral administration of aminosalicylic acid or isoniazid. Eur J Clin Pharmacol. 1974;7(3):217–225. doi:10.1007/BF00560384
   PubMedGoogle Scholar
• Traini D, Young PM. Drug delivery for tuberculosis: is inhaled therapy the key to success? Ther Deliv. 2017;8(10):819–821. doi:10.4155/tde-2017-0050
   PubMed Web of Science ®Google Scholar
• Goyal AK, Garg T, Bhandari S, Rath G. Chapter 22 - advancement in pulmonary drug delivery systems for treatment of tuberculosis. In: Andronescu E, Grumezescu AM, editors. Nanostructures for Drug Delivery. Elsevier; 2017:669–695.
   Google Scholar
• Sharma R, Kaur A, Sharma AK, Dilbaghi N. Nano-based anti-tubercular drug delivery and therapeutic interventions in tuberculosis. Curr Drug Targets. 2017;18(1):72–86. doi:10.2174/1389450116666150804110238
   PubMedGoogle Scholar
• El Zowalaty ME, Al Ali SHH, Husseiny MI, Geilich BM, Webster TJ, Hussein MZ. The ability of streptomycin-loaded chitosan-coated magnetic nanocomposites to possess antimicrobial and antituberculosis activities. Int J Nanomedicine. 2015;10:3269. doi:10.2147/IJN.S74469
   PubMed Web of Science ®Google Scholar
• Hakkimane SS, Shenoy VP, Gaonkar SL, Bairy I, Guru BRJ. Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against Mycobacterium tuberculosis H37Rv strain. Int J Nanomedicine. 2018;13:4303. doi:10.2147/IJN.S163925
   PubMed Web of Science ®Google Scholar
• Walters SB, Hanna BA. Testing of susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by mycobacterium growth indicator tube method. J Clin Microbiol. 1996;34(6):1565–1567. doi:10.1128/jcm.34.6.1565-1567.1996
   PubMedGoogle Scholar
• Tsiaggali M, Andreadou E, Hatzidimitriou A, Pantazaki A, Aslanidis PJ. Copper (I) halide complexes of N-methylbenzothiazole-2-thione: synthesis, structure, luminescence, antibacterial activity and interaction with DNA. J Inorg Biochem. 2013;121:121–128. doi:10.1016/j.jinorgbio.2013.01.001
   PubMed Web of Science ®Google Scholar
• Usman MS, El Zowalaty ME, Shameli K, Zainuddin N, Salama M, Ibrahim NAJ. Synthesis, characterization, and antimicrobial properties of copper nanoparticles. Int J Nanomedicine. 2013;8:4467.
   PubMed Web of Science ®Google Scholar
• Williams DN, Ehrman SH, Holoman TRPJ. Evaluation of the microbial growth response to inorganic nanoparticles. J Nanobiotechnology. 2006;4(1):3. doi:10.1186/1477-3155-4-3
   PubMedGoogle Scholar
• Phumpatrakom P, Ariyakriangkai W, Srisuwan T, Louwakul P. In vitro cytotoxicity of some hemostatic agents used in apicoectomy to human periodontal ligament and bone cells. Saudi Endod J. 2020;10(1):21–27.
   Google Scholar
• Sasaki T, Tamaki J, Nishizawa K, et al. Evaluation of cell viability and metabolic activity of a 3D cultured human epidermal model using a dynamic autoradiographic technique with a PET radiopharmaceutical. Sci Rep. 2019;9(1):10685. doi:10.1038/s41598-019-47153-0
   PubMedGoogle Scholar
• He W, Frost MC. Direct measurement of actual levels of nitric oxide (NO) in cell culture conditions using soluble NO donors. Redox Biol. 2016;9:1–14. doi:10.1016/j.redox.2016.05.002
   PubMed Web of Science ®Google Scholar
• Wang X, Pang H, Chen W, Lin Y, Ning G. Controllable fabrication of high purity Mg(OH)2 nanoneedles via direct transformation of natural brucite. Mater Lett. 2014;120:69–72. doi:10.1016/j.matlet.2014.01.034
   Google Scholar
• Maa X, Maa H, Jianga X, Jianga Z. Preparation of magnesium hydroxide nanoflowers from boron mud via anti-drop precipitation method. Mater Res Bull. 2014;56:6.
   Google Scholar
• Saifullah B, Hussein MZ, Hussein-Al-Ali SH, Arulselvan P, Fakurazi S. Sustained release formulation of an anti-tuberculosis drug based on para-amino salicylic acid-zinc layered hydroxide nanocomposite. Chem Cent J. 2013;7(1):72. doi:10.1186/1752-153X-7-72
   PubMedGoogle Scholar
• Akkaya Y, Infrared AS. Raman spectra, ab initio calculations vibrational assignment of 4-aminosalicylic acid. Vib Spectrosc. 2006;42(22):10. doi:10.1016/j.vibspec.2006.05.011
   Google Scholar
• Panicker CY, John VH. FT-IR, FT-Raman and FT-SERS spectra of 4-aminosalicylic acid sodium salt dihydrate. Spectrochim Acta A Mol Biomol Spectrosc. 2001;58(2):7.
   Google Scholar
• Rabha A, Singh A, Grover S, Kumari A, Pandey B, Grover A. Structural basis for isoniazid resistance in KatG double mutants of Mycobacterium tuberculosis. Microb Pathog. 2019;129:152–160. doi:10.1016/j.micpath.2019.02.003
   PubMedGoogle Scholar
• Heraldy E, Triyono T, Wijaya K, Santosa SJ. Mg/Al hydrotalcite-like synthesized from brine water for eosin yellow removal. Indo J Chem. 2011;11(2):6.
   Google Scholar
• Wu L, Yu L, Xiao X, et al. Recent advances in self-supported layered double hydroxides for oxygen evolution reaction. Research. 2020;2020:17. doi:10.34133/2020/3976278
   Google Scholar
• Gunasekaran S, Sailatha E, Seshadri S, Kumaresan S. FTIR and FT Raman spectra and molecular structural conformation of isoniazid. Indian J Pure Appl Phys. 2009;47:7.
   Google Scholar
• Hong L, Zheng JW. HPLC analysis of para-aminosalicylic acid and its metabolite in plasma, cerebrospinal fluid and brain tissues.. J Pharm Biomed Anal. 2011;54(5):9. doi:10.1016/j.jpba.2010.11.031
   Google Scholar
• Saifullah B, El Zowalaty ME, Arulselvan P, et al. Synthesis, characterization, and efficacy of antituberculosis isoniazid zinc aluminum-layered double hydroxide based nanocomposites. Int J Nanomedicine. 2016;11:3225–3237. doi:10.2147/IJN.S102406
   PubMed Web of Science ®Google Scholar
• Malaguarnera L. Influence of resveratrol on the immune response. Nutrients. 2019;11(5):946. doi:10.3390/nu11050946
   PubMed Web of Science ®Google Scholar
• Schwager J, Richard N, Widmer F, Raederstorff D. Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells. BMC Complement Altern Med. 2017;17(1):17–1823. doi:10.1186/s12906-017-1823-z
   PubMedGoogle Scholar
• van Loo G, Sze M, Bougarne N, et al. Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis. J Mol Endocrinol. 2010;24(2):310–322. doi:10.1210/me.2009-0236
   Google Scholar
• Soonthornsit N, Pitaksutheepong C, Hemstapat W, Utaisincharoen P, Pitaksuteepong T. In vitro anti-inflammatory activity of Morus alba l. stem extract in LPS-stimulated RAW 264.7 cells. Evid Based Complement Alternat Med. 2017;2017:8. doi:10.1155/2017/3928956
   Google Scholar
• Chen L, Deng H, Cui H, et al. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget. 2017;9(6):7204–7218. doi:10.18632/oncotarget.23208
   PubMedGoogle Scholar
• Gonçalves JM, Martins PR, Angnes L, Araki K. Recent advances in ternary layered double hydroxide electrocatalysts for the oxygen evolution reaction. New J Chem. 2020;44(24):9981–9997. doi:10.1039/D0NJ00021C
   Google Scholar
• Saifullah B, Chrzastek A, Maitra A, et al. Novel anti-tuberculosis nanodelivery formulation of ethambutol with graphene oxide. Molecules. 2017;22(10):1560. doi:10.3390/molecules22101560
   PubMedGoogle Scholar
• Choi G, Rejinold NS, Piao H, Choy J-H. Inorganic–inorganic nanohybrids for drug delivery, imaging and photo-therapy: recent developments and future scope. Chem Sci. 2021;12(14):5044–5063. doi:10.1039/D0SC06724E
   PubMed Web of Science ®Google Scholar
• Wu Y, Pang H, Liu Y, et al. Environmental remediation of heavy metal ions by novel-nanomaterials: a review. Environ Pollut. 2019;246:608–620. doi:10.1016/j.envpol.2018.12.076
   PubMed Web of Science ®Google Scholar
• Nabipour H, Jafari SH, Naderikalali E, Mozafari M. Mefenamic acid-layered zinc hydroxide nanohybrids: a new platform to elaborate drug delivery systems. J Inorg Organomet Polym Mater. 2018. doi:10.1007/s10904-018-0998-1
   Google Scholar
• Hashim N, Sharif SNM, Muda Z, et al. Preparation of zinc layered hydroxide-ferulate and coated zinc layered hydroxide-ferulate nanocomposites for controlled release of ferulic acid. Mater Res Innov. 2019;23(4):233–245. doi:10.1080/14328917.2018.1444696
   Google Scholar