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ORIGINAL RESEARCH

Cellular Uptake of Silica Particles Influences EGFR Signaling Pathway and is Affected in Response to EGF

, , , & ORCID Icon
Pages 1047-1061 | Received 15 Sep 2022, Accepted 03 Feb 2023, Published online: 24 Feb 2023

References

  • Herbst RS. Review of epidermal growth factor receptor biology. Int J Radiat Oncol. 2004;59(2):S21–S26. doi:10.1016/j.ijrobp.2003.11.041
  • Wee P, Wang Z. Epidermal growth factor receptor cell proliferation signaling pathways. Cancers. 2017;9(5):52. doi:10.3390/cancers9050052
  • Capuani F, Conte A, Argenzio E, et al. Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells. Nat Commun. 2015;6(1):7999. doi:10.1038/ncomms8999
  • Pinilla-Macua I, Grassart A, Duvvuri U, Watkins SC, Sorkin A. EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo. Elife. 2017;6. doi:10.7554/eLife.31993
  • Roepstorff K, Grandal MV, Henriksen L, et al. Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic. 2009;10(8):1115–1127. doi:10.1111/j.1600-0854.2009.00943.x
  • Freed DM, Bessman NJ, Kiyatkin A, et al. EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics. Cell. 2017;171(3):683–695.e18. doi:10.1016/j.cell.2017.09.017
  • Madshus IH, Stang E. Internalization and intracellular sorting of the EGF receptor: a model for understanding the mechanisms of receptor trafficking. J Cell Sci. 2009;122(19):3433–3439. doi:10.1242/jcs.050260
  • Sigismund S, Avanzato D, Lanzetti L. Emerging functions of the EGFR in cancer. Mol Oncol. 2018;12(1):3–20. doi:10.1002/1878-0261.12155
  • Harms BD, Bassi GM, Horwitz AR, Lauffenburger DA. Directional persistence of EGF-induced cell migration is associated with stabilization of lamellipodial protrusions. Biophys J. 2005;88(2):1479–1488. doi:10.1529/biophysj.104.047365
  • Price JT, Tiganis T, Agarwal A, Djakiew D, Thompson EW. Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 3’-kinase and phospholipase C-dependent mechanism. Cancer Res. 1999;59(21):5475–5478.
  • Yamaguchi H, Wyckoff J, Condeelis J. Cell migration in tumors. Curr Opin Cell Biol. 2005;17(5):559–564. doi:10.1016/j.ceb.2005.08.002
  • Master AM, Sen Gupta A. EGF receptor-targeted nanocarriers for enhanced cancer treatment. Nanomedicine. 2012;7(12):1895–1906. doi:10.2217/nnm.12.160
  • Zhao J, Stenzel MH. Entry of nanoparticles into cells: the importance of nanoparticle properties. Polym Chem. 2018;9(3):259–272. doi:10.1039/C7PY01603D
  • Doane TL, Burda C. The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy. Chem Soc Rev. 2012;41(7):2885. doi:10.1039/c2cs15260f
  • Liberman A, Mendez N, Trogler WC, Kummel AC. Synthesis and surface functionalization of silica nanoparticles for nanomedicine. Surf Sci Rep. 2014;69(2–3):132–158. doi:10.1016/j.surfrep.2014.07.001
  • da Santos ES, Nogueira KAB, Fernandes LCC, et al. EGFR targeting for cancer therapy: pharmacology and immunoconjugates with drugs and nanoparticles. Int J Pharm. 2021;592:120082. doi:10.1016/j.ijpharm.2020.120082
  • Silva CO, Petersen SB, Reis CP, et al. EGF functionalized polymer-coated gold nanoparticles promote EGF photostability and EGFR internalization for photothermal therapy. Antopolsky M, ed. PLoS One. 2016;11(10):e0165419. doi:10.1371/journal.pone.0165419
  • She X, Chen L, Velleman L, et al. The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery. J Mater Chem B. 2015;3(29):6094–6104. doi:10.1039/C5TB00790A
  • Corbo C, Molinaro R, Parodi A, Toledano Furman NE, Salvatore F, Tasciotti E. The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery. Nanomedicine. 2016;11(1):81–100. doi:10.2217/nnm.15.188
  • Monopoli MP, Walczyk D, Campbell A, et al. Physical−chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J Am Chem Soc. 2011;133(8):2525–2534. doi:10.1021/ja107583h
  • Sousa de Almeida M, Susnik E, Drasler B, Taladriz-Blanco P, Petri-Fink A, Rothen-Rutishauser B. Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine. Chem Soc Rev. 2021;7:2885–2911. doi:10.1039/d0cs01127d
  • Ma L, Kohli M, Smith A. Nanoparticles for combination drug therapy. ACS Nano. 2013;7(11):9518–9525. doi:10.1021/nn405674m
  • Phuc L, Taniguchi A. Epidermal growth factor enhances cellular uptake of polystyrene nanoparticles by clathrin-mediated endocytosis. Int J Mol Sci. 2017;18(6):1301. doi:10.3390/ijms18061301
  • Stöber W, Fink A, Bohn E. Controlled growth of monodisperse silica spheres in the micron size range. J Colloid Interface Sci. 1968;26(1):62–69. doi:10.1016/0021-9797(68)90272-5
  • Larson DR, Ow H, Vishwasrao HD, Heikal AA, Wiesner U, Webb WW. Silica nanoparticle architecture determines radiative properties of encapsulated fluorophores. Chem Mater. 2008;20(8):2677–2684. doi:10.1021/cm7026866
  • Crippa F, Rodriguez-Lorenzo L, Hua X, et al. Phase transformation of superparamagnetic iron oxide nanoparticles via thermal annealing: implications for hyperthermia applications. ACS Appl Nano Mater. 2019;2(7):4462–4470. doi:10.1021/acsanm.9b00823
  • Fong W-K-K, Moore TL, Balog S, et al. Nanoparticle behaviour in complex media: methods for characterizing physicochemical properties, evaluating protein corona formation, and implications for biological studies. In: NanoScience and Technology. Springer;2019:101–150. doi:10.1007/978-3-030-12461-8_5
  • Stauffer W, Sheng H, Lim HN. EzColocalization: an ImageJ plugin for visualizing and measuring colocalization in cells and organisms. Sci Rep. 2018;8(1). doi:10.1038/s41598-018-33592-8
  • Sousa de Almeida M, Taladriz-Blanco P, Drasler B, et al. Cellular uptake of silica and gold nanoparticles induces early activation of nuclear receptor NR4A1. Nanomaterials. 2022;12(4):690. doi:10.3390/nano12040690
  • Moore TL, Rodriguez-Lorenzo L, Hirsch V, et al. Nanoparticle colloidal stability in cell culture media and impact on cellular interactions. Chem Soc Rev. 2015;44(17):6287–6305. doi:10.1039/C4CS00487F
  • Shapero K, Fenaroli F, Lynch I, Cottell DC, Salvati A, Dawson KA. Time and space resolved uptake study of silica nanoparticles by human cells. Mol BioSyst. 2011;7(2):371–378. doi:10.1039/C0MB00109K
  • Uboldi C, Bonacchi D, Lorenzi G, et al. Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441. Part Fibre Toxicol. 2009;6(1):18. doi:10.1186/1743-8977-6-18
  • Kim KJ, Kim MK, Rhie JW, et al. Silica nanoparticles increase human adipose tissue-derived stem cell proliferation through ERK1/2 activation. Int J Nanomedicine. 2015:2261. doi:10.2147/IJN.S71925
  • Wittig A, Gehrke H, Del Favero G, et al. Amorphous silica particles relevant in food industry influence cellular growth and associated signaling pathways in human gastric carcinoma cells. Nanomaterials. 2017;7(1):18. doi:10.3390/nano7010018
  • Behzadi S, Serpooshan V, Tao W, et al. Cellular uptake of nanoparticles: journey inside the cell. Chem Soc Rev. 2017;46(14):4218–4244. doi:10.1039/C6CS00636A
  • Gustafson HH, Holt-Casper D, Grainger DW, Ghandehari H. Nanoparticle uptake: the phagocyte problem. Nano Today. 2015;10(4):487–510. doi:10.1016/j.nantod.2015.06.006
  • Guo X, Huang L. Recent advances in non-viral vectors for gene delivery. Acc Chem Res. 2013;45(7):971–979. doi:10.1021/ar200151m.Recent
  • Nakase I, Kobayashi NB, Takatani-Nakase T, Yoshida T. Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic ras expression potentiates cellular uptake efficacy of exosomes. Sci Rep. 2015;5(1):10300. doi:10.1038/srep10300
  • Schelch K, Vogel L, Schneller A, et al. EGF induces migration independent of EMT or invasion in A549 lung adenocarcinoma cells. Front Cell Dev Biol. 2021;9. doi:10.3389/fcell.2021.634371
  • Yoon Y-K, Kim H-P, Han S-W, et al. KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach. Mol Carcinog. 2010;49(4):353–362. doi:10.1002/mc.20607
  • Tanaka T, Zhou Y, Ozawa T, et al. Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation. J Biol Chem. 2018;293(7):2288–2301. doi:10.1074/jbc.M117.811299
  • Gehrke H, Frühmesser A, Pelka J, et al. In vitro toxicity of amorphous silica nanoparticles in human colon carcinoma cells. Nanotoxicology. 2012;7(3):274–293. doi:10.3109/17435390.2011.652207