References
- HollandECGliomagenesis: genetic alterations and mouse modelsNature Rev Genet20012210201129
- NicholasMKGlioblastoma multiforme: evidence-based approach to therapyExpert Rev Anticancer Ther2007712S23S2718076314
- HengartnerMOThe biochemistry of apoptosisNature200040680577077611048727
- MercerRWTylerMAUlasovI VLesniakMSTargeted therapies for malignant glioma: progress and potentialBio Drugs20092312535
- BrennanCMomotaHHambardzumyanDGlioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterationsPLoS One2009411e775219915670
- PinesJFour-dimensional control of the cell cycleNat Cell Biol199913E73E7910559915
- TashiroETsuchiyaAImotoMFunctions of cyclin D1 as an oncogene and regulation of cyclin D1 expressionCancer Sci200798562963517359287
- DaiCHollandECAstrocyte differentiation states and glioma formationCancer J200392728112784872
- SpiraAICarducciMADifferentiation therapyCurr Opin Pharmacol20033433834312901941
- LiuXYangJMZhangSSLiuXYLiuDXInduction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximideBMC Cancer20101068421159181
- BoulaizHAlvarezPJRamirezANanomedicine: application areas and development prospectsInt J Mol Sci20111253303332121686186
- VizirianakisISNanomedicine and personalized medicine toward the application of pharmacotyping in clinical practice to improve drug-delivery outcomesNanomedicine201171111721094279
- WongHLBendayanRRauthAMYongqiangLWuXYChemotherapy with anticancer drugs encapsulated in solid lipid nanoparticlesAdv Drug Deliv Rev200759649150417532091
- LockmanPRKoziaraJRoderKEIn vivo and in vitro assessment of baseline blood–brain barrier parameters in the presence of novel nanoparticlesPharm Res200320570571312751624
- Garcia-GarciaEAndrieuxKGilSCouvreurPColloidal carriers and blood–brain barrier (BBB) translocation: a way to deliver drugs to the brain? Int J Pharm2005298227429215896933
- PohlmannARMezzaliraGVenturinCDetermining the simultaneous presence of drug nanocrystals in drug-loaded polymeric nanocapsule aqueous suspensions: a relation between light scattering and drug contentInt J Pharm20083591–228829318495390
- BernardiABraganholEJägerEIndomethacin-loaded nano-capsules treatment reduces in vivo glioblastoma growth in a rat glioma modelCancer Lett20092811536319286307
- BernardiAFrozzaRLHornA PProtective effects of indomethacin-loaded nanocapsules against oxygen-glucose deprivation in organotypic hippocampal slice cultures: involvement of neuroinflammationNeurochem Int201057662963620691236
- FrozzaRLBernardiAPaeseKCharacterization of transresveratrol-loaded lipid-core nanocapsules and tissue distribution studies in ratsJ Biomed Nanotechnol20106669470321361135
- BernardiAZilbersteinACJägerEEffects of indomethacin-loaded nanocapsules in experimental model of inflammation in ratsBr J Pharmacol200915841104111119422380
- FessiHPuisieuxFDevissaguetJ PAmouryNBenitaSNanocapsules formation by interfacial polymer deposition following solvent displacementInt J Pharm1989113r1r4
- JägerEVenturiniCGPolettoFSSustained release from lipid-core nanocapsules by varying the core viscosity and the particle surface areaJ Biomed Nanotechnol20095113014020055116
- JornadaDSFielLABuenoKLipid-core nanocapsules: mechanism of self-assembly, control of size and loading capacitySoft Matter2012826462655
- PohlmannARSoaresLUCruzLDa SilveiraN PGuterresSSAlkaline hydrolysis as a tool to determine the association form of indomethacin in nanocapsules prepared with poly(epsilon-caprolactone)Curr Drug Deliv20041210311016305375
- LenzGGonçalvesDLuoZAvruchJRodnightRNearyJExtracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte culturesJ Neurochem20017741001100911359865
- BernardiAFrozzaRLJägerESelective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro studyEur J Pharmacol20085861–3243418371953
- Zanotto-FilhoABraganholESchröderRNFκB inhibitors induce cell death in glioblastomasBiochem Pharmacol201181341242421040711
- PetersonGLReview of the folin-phenol protein quantification method of Lowry, Rosebrough, Farr and RandallAnal Biochem19791002201220393128
- VivancoISawyersCLThe phosphatidylinositol 3-Kinase AKT pathway in human cancerNat Rev Cancer20022748950112094235
- ZhangJHuangKShiZHigh b-catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expressionNeuro Oncol201113660060921636708
- WieseCRolletschekAKaniaGNestin expression – a property of multi-lineage progenitor cells? Cell Mol Life Sci20046119–202510252215526158
- StrojnikTRoslandG VSakariassenPOKavalarRLahTNeural stem cell markers, nestin, and musashi proteins in the progression of human glioma: correlation of nestin with prognosis of patient survivalSurg Neurol200768213314317537489
- LamprechtABenoitJ PEtoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibitionJ Control Release2006112220821316574265
- WrightSCZhongJLarrickJ WInhibition of apoptosis as a mechanism of tumor promotionFASEB J1994896546608005393
- CollinsKJacksTPaveltichNPThe cell cycle and cancerProc Natl Acad Sci U S A1997947277627789096291
- LoweSWBodisSMcClatcheyAp53 status and the efficacy of cancer therapy in vivoScience199426651868078107973635
- JaattelaMMultiple cell death pathways as regulators of tumour initiation and progressionOncogene200423162746275615077138
- RaoSKEdwardsJJoshiADSiuIMRigginsGJA survey of glioblastoma genomic amplifications and deletionsJ Neurooncol201096216917919609742
- ChengJQAltomareDAKleinMATransforming activity and cell cycle-dependent expression of the AKT2 oncogene: evidence for a link between cell cycle regulation and oncogenesisOncogene19971423279328019190895
- SawyersCLRational therapeutic intervention in cancer: kinases as drug targetsCurr Opin Genet Dev200212111111511790564
- WidelitzRWnt signaling through canonical and non-canonical pathways: recent progressGrowth Factors200523211111616019432
- ChengJQLindsleyCWChengGZYangHNicosiaSVThe Akt/PKB pathway: molecular target for cancer drug discoveryOncogene200524507482749216288295
- YochumGSClelandRGoodmanRHA genome-wide screen for beta-catenin binding sites identifes a downstream enhancer element that controls c-Myc gene expressionMol Cell Biol200828247368737918852287
- SareddyGRPanigrahiMChallaSMahadevanABabuPPActivation of Wnt/beta-catenin/Tcf signaling pathway in human astrocytomasNeurochem Int200955530731719576519
- Dal ColJDolcettiRGSK-3beta inhibition: at the crossroad between Akt and mTOR constitutive activation to enhance cyclin D1 protein stability in mantle cell lymphomaCell Cycle20087182813281618769147
- OngCSZhouJOngCNShenHMLuteolin induces G1 arrest in human nasopharyngeal carcinoma cells via the Akt-GSK-3beta-Cyclin D1 pathwayCancer Lett2010298216717520655656
- Takahashi-YanagaFSasaguriTGSK-3beta regulates cyclin D1 expression: a new target for chemotherapyCell Signal200820458158918023328
- LeszczynieckaMRobertsTDentPGrantSFisherPBDifferentiation therapy of human cancer: basic science and clinical applicationsPharmacol Ther2001902–310515611578655
- PetrieKZelentAWaxmanSDifferentiation therapy of acute myeloid leukemia: past, present and futureCurr Opin Hematol2009162849119468269
- KawamataHTachibanaMFujimoriTImaiYDifferentiation-inducing therapy for solid tumorsCurr Pharm Des200612337938516454751
- RoymansDVissenbergKDe JongheCPhosphatidylinositol 3-kinase activity is required for the expression of glial fibrillary acidic protein upon cAMP-dependent induction of differentiation in rat C6 gliomaJ Neurocehm2001762610618
- DuffyPEHuangY YRapportMMThe relationship of glial fbril-lary acidic protein to the shape, motility, and differentiation of human astrocytoma cellsExp Cell Res198213911451577200901
- RutkaJTHubbardSLFukuyamaKMatsuzawaKDirksPBBeckerLEEffects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cellsCancer Res19945412326732728205549
- TohyamaTLeeVMYRorkeLBMarvinMMcKayRDGTrojanowskiJQNestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cellsLab Invest19926633033131538585
- SinghSKHawkinsCClarkeIDIdentification of human brain tumour initiating cellsNature2004432701539640115549107
- GeorgopoulouNHurelCPolitisPKGaitanouMMatsasRThomaidouDBM88 is a dual function molecule inducing cell cycle exit and neuronal differentiation of neuroblastoma cells via cyclin D1 down-regulation and retinoblastoma protein hypophosphorylationJ Biol Chem200628144336063362016893893
- Strasberg RieberMRieberMSuppression of cyclin D1 but not cdk4 or cyclin A with induction of melanoma terminal differentiationBiochem Biophys Res Commun199521614224277488122
- NishiKInoueHSchnierJBRiceRHCyclin D1 downregulation is important for permanent cell cycle exit and initiation of differentiation induced by anchorage-deprivation in human keratinocytesJ Cell Biochem20091061637219021145