100
Views
40
CrossRef citations to date
0
Altmetric
Review

Clinical significance of metallothioneins in cell therapy and nanomedicine

, , , &
Pages 1477-1488 | Published online: 16 Apr 2013

References

  • MarghoshesMValleeBLA cadmium protein from equine kidney cortexJ Am Chem Soc19577948134814
  • ItohMEbadiMSwansonSThe presence of zinc-binding proteins in brainJ Neurochem19834138238296875568
  • RuppHWeserUConversion of metallothionein into Cu-thionein, the possible low molecular weight form of neonatal hepatic mitochondrocupreinFEBS Lett19744432932974472041
  • VasakMGaldesAHillHAKagiJHBremnerIYoungBWInvestigation of the structure of metallothioneins by proton nuclear magnetic resonance spectroscopyBiochemistry19801934164257356935
  • VasakMKagiJHHillHAZinc(II), cadmium(II), and mercury(II) thiolate transitions in metallothioneinBiochemistry19812010285228567248252
  • BoulangerYGoodmanCMForteCPFesikSWArmitageIMModel for mammalian metallothionein structureProc Natl Acad Sci U S A1983806150115056572910
  • BraunWVasakMRobbinsAHComparison of the NMR solution structure and the X-ray crystal structure of rat metallothionein-2Proc Natl Acad of Sci U S A1992892110124101281438200
  • ZanggerKOzGOtvosJDArmitageIMThree-dimensional solution structure of mouse (Cd7)-metallothionein-1 by homonuclear and heteronuclear NMR spectroscopyProtein Sci19998122630263810631978
  • NielsenAEBohrAPenkowaMThe balance between life and death of a cell: role of metallothioneinsBiomark Insights200719911119690641
  • PastoreAPiemonteFS-glutathionylation signaling in cell biology: progress and prospectsEur J Pharm Sci201246527929222484331
  • KhataiLGoesslerWLorencovaHZanggerKModulation of nitric oxide-mediated metal release from metallothionein by the redox state of glutathione in vitroEur J Biochem2004271122408241615182356
  • HelalGKAleisaAMHelalOKMetallothionein induction reduces caspase-3 activity and TNFalpha levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated ratsOxid Med Cell Longev200921263520046642
  • MinKSPhysiological significance of metallothionein in oxidative stressYakugaku Zasshi20071274695702 Japanese [with English abstract]17409699
  • KooncumchooPSharmaSPorterJGovitrapongPEbadiMCoenzyme Q10 provides neuroprotection in iron-induced apoptosis in dopaminergic neuronsJ Mol Neurosci200628212514116679553
  • NathRKambadurRGulatiSPaliwalVKSharmaMMolecular aspects, physiological function, and clinical significance of metallothioneinsCrit Rev Food Sci Nutr198827141853293923
  • UchidaYTakioKTitaniKIharaYTomonagaMThe growth inhibitory factor that is deficient in the Alzheimer’s disease brain is a 68 amino acid metallothionein-like proteinNeuron1991723373471873033
  • SmithEDrewPATianZQMetallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylationMol Cancer200544216351731
  • SharmaSKEbadiMMetallothionein attenuates 3-morpoholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neuronsAntioxid Redox Signal20035325126412880480
  • EbadiMSharmaSKPeroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson’s diseaseAntioxid Redox Signal20035331933512880486
  • EbadiMSharmaSMetallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson’s diseaseExp Biol Med (Maywood)200623191576158317018883
  • EbadiMBrown-BorgHEl RefaeyHMetallothionein-mediated neuroprotection in genetically engineered mouse models of Parkinson’s diseaseBrain Res Mol Brain Res20051341677515790531
  • EbadiMSharmaSWanpenSShavaliSMetallothionein isoforms attenuate peroxynityrite-induced oxidative stress in Parkinson’s diseaseEbadiMPfeifferRFParkinson’s DiseaseBoca Raton, FLCRC Press2004739765
  • EbadiMSharmaSKMuralikrishnanDMTs provides ubiquinone-mediated neuroprotection in Parkinson’s diseaseProc West Pharmacol Soc200245363812434520
  • EbadiMSharmaSKGhafourifarPBrown-BorgHEl RefaeyHPeroxynitrite in the pathogenesis of Parkinson’s disease and the neuroprotective role of metallothioneinsMethods Enzymol200539627629816291239
  • SharmaSEbadiMMetallothioneins as early and sensitive biomarkers of redox signaling in neurodegenerative disordersThe IIOAB Journal20112698106
  • SharmaSEbadiMTherapeutic potential of metallothioneins as anti-inflammatory agents in polysubstance abuseThe IIOAB Journal2011265061
  • LeeSJKohJYRoles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytesMol Brain2010313020974010
  • SonnKPankratovaSKorshunovaIA metallothionein mimetic peptide protects neurons against kainic acid-induced excitotoxicityJ Neurosci Res20108851074108219937811
  • DakshinamurtiKSharmaSKSundaramMWatanabeTHippocampal changes in developing postnatal mice following intrauterine exposure to domoic acidJ Neurosci19931310448644958105041
  • GillSSHouYGhaneTPulidoOMRegional susceptibility to domoic acid in primary astrocyte cells cultured from the brain stem and hippocampusMar Drugs200861253818648670
  • PulidoOMDomoic acid toxicologic pathology: a reviewMar Drugs20086218021918728725
  • RueEBrulandKDomoic acid binds iron and copper: a possible role for the toxin produced by the marine diatom Pseudo-nitzschiaMarine Chemistry200176127134
  • PedersenDSFredericiaPMPedersenMOMetallic gold slows disease progression, reduces cell death and induces astrogliosis while simultaneously increasing stem cell responses in an EAE rat model of multiple sclerosisHistochem Cell Biol2012138578780222820857
  • ZappiaECasazzaSPedemonteEMesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergyBlood200510651755176115905186
  • LanzaCMorandoSVociANeuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivoJ Neurochem200911051674168419619133
  • MickovaABuzgoMBenadaOCore/shell nanofibers with embedded liposomes as a drug delivery systemBiomacromolecules201213495296222401557
  • ChenXAZhangLJHeZJPlasmid-encapsulated polyethylene glycol-grafted polyethylenimine nanoparticles for gene delivery into rat mesenchymal stem cellsInt J Nanomedicine2011684385321589652
  • ScottRCRosanoJMIvanovZTargeting VEGF-encapsulated immunoliposomes to MI heart improves vascularity and cardiac functionFASEB J200923103361336719535683
  • HofkensWGreversLCWalgreenBIntravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritisJ Control Release2011152336336921396411
  • TangSLiuZZhaoLZouZDuMTransfection of pEGFP-C2 in brain mediated by targeting liposome P-MMA-DOSPERSheng Wu Yi Xue Gong Cheng Xue Za Zhi200825511701174 Chinese19024469
  • GiulianiALWienerELeeMJBrownINBertiGWickramasingheSNChanges in murine bone marrow macrophages and erythroid burst-forming cells following the intravenous injection of liposome-encapsulated dichloromethylene diphosphonate (Cl2MDP)Eur J Haematol200166422122911380601
  • AksentijevichIPastanILunardi-IskandarYGalloRCGottesmanMMThierryARIn vitro and in vivo liposome-mediated gene transfer leads to human MDR1 expression in mouse bone marrow progenitor cellsHum Gene Ther199679111111228773513
  • RahmanYEHansonWRBharuchaJAinsworthEJJaroslowBNMechanisms of reduction of antitumor drug toxicity by liposome encapsulationAnn N Y Acad Sci1978308325342279296
  • WangYZengBLiXExpression of human calcitonin by microencapsulated recombinant myoblastsBiotechnol Lett200628181453145816823598
  • XieYYeLZhangXTransport of nerve growth factor encapsulated into liposomes across the blood–brain barrier: in vitro and in vivo studiesJ Control Release20051051–210611915893839
  • HatakeyamaHItoEYamamotoMA DNA microarray-based analysis of the host response to a nonviral gene carrier: a strategy for improving the immune responseMol Ther20111981487149821386823
  • HatakeyamaHAkitaHItoESystemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipidBiomaterials201132184306431621429576
  • HatakeyamaHAkitaHHarashimaHA multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemmaAdv Drug Deliv Rev201163315216020840859
  • KawaguchiATKametaniYKatoSFuruyaHTamaokiKHabuSEffects of liposome-encapsulated hemoglobin on human immune system: evaluation in immunodeficient mice reconstituted with human cord blood stem cellsArtif Organs200933216917619178463
  • WongAModified epidermal growth factor receptor (EGFR)-bearing liposomes (MRBLs) are sensitive to EGF in solutionPLoS One2009410e739119816581
  • XiaoQXiaoCPreparation and characterization of silica-coated magnetic-fluorescent bifunctional microspheresNanoscale Res Lett2009491078108420596403
  • LeungKQuantum dot-prostate-specific membrane antigen antibody J591Molecular Imaging and Contrast Agent Database (MICAD)Bethesda, MDNational Center for Biotechnology Information2005 Available from: http://www.ncbi.nlm.nih.gov/books/NBK23039/pdf/QD-PMSA.pdfAccessed February 20, 2013
  • ChoiYKimKHongSKimHKwonYJSongRIntracellular protein target detection by quantum dots optimized for live cell imagingBioconjug Chem20112281576158621718016
  • LinCHChangLWChangHThe chemical fate of the Cd/Se/Te-based quantum dot 705 in the biological system: toxicity implicationsNanotechnology2009202121510119423922
  • ChangCCSunKWLeeSFKanLSSelf-assembled molecular magnets on patterned silicon substrates: bridging bio-molecules with nanoelectronicsBiomaterials200728111941194717223191
  • PeyrotCGagnonCGagneFWillkinsonKJTurcottePSauveSEffects of cadmium telluride quantum dots on cadmium bioaccumulation and metallothionein production to the freshwater mussel, Elliptio complanataComp Biochem Physiol C Toxicol Pharmacol200915024625119427919
  • WeiLThakkarMChenYNtimSAMitraSZhangXCytotoxicity effects of water dispersible oxidized multiwalled carbon nanotubes on marine alga, Dunaliella tertiolectaAquat Toxicol2010100219420120673592
  • MounicouSOuerdaneLL’AzouBIdentification of metallothionein subisoforms in HPLC using accurate mass and online sequencing by electrospray hybrid linear ion trap-orbital ion trap mass spectrometryAnal Chemistry2010821669476957
  • NeupaneKPDeveloping Metallothionein Capped Cadmium Selenide Nanoparticles [doctoral thesis]Detroit, MIWayne State University2005
  • BrennemanMSharmaSHartingMAutologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged ratsJ Cereb Blood Flow Metab201030114014919773802
  • YangBStrongRSharmaSTherapeutic time window and dose response of autologous bone marrow mononuclear cells for ischemic strokeJ Neurosci Res201189683383921412816
  • MisraVYangBSharmaSSavitzSCell-based therapy for strokeCoxCSProgenitor Cell Therapy for Neurological InjuryNew York, NYHumana Press2011143162
  • SharmaSYangBStrongRBone marrow mononuclear cells protect neurons and modulate microglia in cell culture models of ischemic strokeJ Neurosci Res201088132869287620629187
  • SharmaSYangBXiXGrottaJAronowskiJSavitzSIIL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathwaysBrain Res2011137318919421138740
  • El KhouryRMisraVSharmaSThe effect of transcatheter injections on viability and cytokine release of mononuclear cellsAJNR Am J Neuroradiol20103181488149220395386
  • SharmaSEbadiMIn vivo molecular imaging in Parkinson’s diseasePfeifferRFWszolekZKEbadiMParkinson’s Disease2nd edBoca Raton, FLCRC Press2013787802
  • LiuZRenGZhangTYangZAction potential changes associated with inhibitory effects on voltage-gated sodium currents of hippocampal CA1 neurons by silver nanoparticlesToxicology2009246317918419683029
  • HaaseARottSMantionAEffects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responsesToxicol Sci2012126245746822240980
  • LutherEMSchmidtMMDiendorfJEppleMDringenRUpregulation of metallothioneins after exposure of cultured primary astrocytes to silver nanoparticlesNeurochem Res20123781639164822476984
  • PanJFBuffetPEPoirierLSize dependent bioaccumulation and ecotoxicity of gold nanoparticles in an endobenthic invertebrate: the Tellinid clam Scrobicularia planaEnviron Pollut2012168374322595760
  • PanYLeifertAGrafMHigh-sensitivity real-time analysis of nanoparticle toxicity in green fluorescent protein-expressing zebrafishSmall Epub 2012 Nov 12
  • FanJGallagherJWWuHJLow molecular weight protein enrichment on mesoporous silica thin films for biomarker discoveryJ Vis Exp201262387622546927
  • SteenlandKStaynerLSilica, asbestos, man-made mineral fibers, and cancerCancer Causes Control1997834915039498906
  • Bertoni-FreddariCFattorettiPCasoliTDi StefanoGGiorgettiBBaliettiMBrain aging: the zinc connectionExp Gerontol200843538939318078729
  • MocchegianiECostarelliLGiacconiRPiacenzaFBassoAMalavoltaMMicronutrient (Zn, Cu, Fe)-gene interactions in ageing and inflammatory age-related diseases: implications for treatmentsAgeing Res Rev201211229731922322094
  • DerfusAMChanWCWBhatiaSNProbing the cytotoxicity of semiconductor quantum dotsNano Lett2004411118
  • LeighKBouldinJBuchananREffects of exposure to semiconductor nanoparticles on aquatic organismsJ Toxicol2012201239765722131989
  • PenkowaMMetallothioneins are multipurpose neuroprotectants during brain pathologyFEBS J200627391857187016640552
  • PenkowaMTioLGiraltMSpecificity and divergence in the neurobiologic effects of different metallothioneins after brain injuryJ Neurosci Res200683697498416493670
  • StankovicRKChungRSPenkowaMMetallothioneins I and II: neuroprotective significance during CNS pathologyInt J Biochem Cell Biol200739348448917097331
  • LansdownABMirastschijskiUStubbsNScanlonEAgrenMSZinc in wound healing: theoretical, experimental, and clinical aspectsWound Repair Regen200715121617244314
  • WongKKCheungSOHuangLFurther evidence of the anti-inflammatory effects of silver nanoparticlesChem Med Chem2009471129113519405063
  • RajenderGNarayananNGLiquid chromatography-tandem mass spectrometry method for determination of sirolimus coated drug eluting nano porous carbon stentsBiomed Chromatogr201024332933419662626
  • KaragkiozakiVCLogothetidisSDKassavetisSNGiannoglouGDNanomedicine for the reduction of the thrombogenicity of stent coatingsInt J Nanomedicine2010523924820463940