252
Views
14
CrossRef citations to date
0
Altmetric
Original Research

Toxicity of 100 nm zinc oxide nanoparticles: a report of 90-day repeated oral administration in Sprague Dawley rats

, , , , , , , , , , , , , , , , , , , & show all
Pages 109-126 | Published online: 15 Dec 2014

References

  • OsmondMJMcCallMJZinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazardNanotoxicology201041154120795900
  • OsmanIFBaumgartnerACemeliEFletcherJNAndersonDGenotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cellsNanomedicine (Lond)2010581193120321039197
  • BecheriADürrMLo NostroPBaglioniPSynthesis and characterization of zinc oxide nanoparticles: application to textiles as UV-absorbersJ Nanopart Res2008104679689
  • LinCCLinWHLiYYSynthesis of ZnO nanowires and their applications as an ultraviolet photodetectorJ Nanosci Nanotechnol2009952813281919452935
  • JinYWangJSunBBlakesleyJCGreenhamNCSolution-processed ultraviolet photodetectors based on colloidal ZnO nanoparticlesNano Lett2008861649165318459745
  • HengBCZhaoXXiongSNgKWBoeyFYLooJSToxicity of zinc oxide (ZnO) nanoparticles on human bronchial epithelial cells (BEAS-2B) is accentuated by oxidative stressFood Chem Toxicol20104861762176620412830
  • LeeSPieJ-EKimY-RLeeHSonSKimM-KEffects of zinc oxide nanoparticles on gene expression profile in human keratinocytesMol Cell Toxicol201282113118
  • ChoiS-JLeeJJeongJChoyJ-HToxicity evaluation of inorganic nanoparticles: considerations and challengesMol Cell Toxicol201393205210
  • JangYLeeEParkY-HThe potential for skin irritation, phototoxicity, and sensitization of ZnO nanoparticlesMol Cel Toxicol201282171177
  • SharmaVSinghPPandeyAKDhawanAInduction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticlesMutat Res20127451–2849122198329
  • YanGHuangYBuQZinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in ratsJ Environ Sci Health A Tox Hazard Subst Environ Eng201247457758822375541
  • SurekhaPKishoreASSrinivasARepeated dose dermal toxicity study of nano zinc oxide with Sprague–Dawley ratsCutan Ocul Toxicol2012311263221830917
  • PasupuletiSAlapatiSGanapathySAnumoluGPullyNRPrakhyaBMToxicity of zinc oxide nanoparticles through oral routeToxicol Ind Health201228867568622033421
  • HoMWuKYCheinHMChenLCChengTJPulmonary toxicity of inhaled nanoscale and fine zinc oxide particles: mass and surface area as an exposure metricInhal Toxicol2011231494795622122307
  • YuBZhangYZhengWFanCChenTPositive surface charge enhances selective cellular uptake and anticancer efficacy of selenium nanoparticlesInorganic chemistry201251168956896322873404
  • NagyASteinbruckAGaoJDoggettNHollingsworthJAIyerRComprehensive analysis of the effects of CdSe quantum dot size, surface charge, and functionalization on primary human lung cellsACS Nano2012664748476222587339
  • YinHCaseyPSMcCallMJFenechMEffects of surface chemistry on cytotoxicity, genotoxicity, and the generation of reactive oxygen species induced by ZnO nanoparticlesLangmuir20102619153991540820809599
  • KimK-MKimT-HKimH-MColloidal behaviors of ZnO nanoparticles in various aqueous mediaToxicol Environ Health Sci201242121131
  • Organisation for Economic Co-operation and DevelopmentTest No 408: Repeated Dose 90-Day Oral Toxicity Study in RodentsParis, FranceOECD Publishing10.1787/9789264070707-en
  • Ministry of Agriculture, Food and Rural AffairsAnimal Protection ActRepublic of Korea; Korea Legislation Research Institute2011 Available from: http://elaw.klri.re.kr/eng_service/lawView.do?hseq=29131&lang=ENGAccessed November 10, 2014
  • SeokSHChoWSParkJSRat pancreatitis produced by 13-week administration of zinc oxide nanoparticles: biopersistence of nanoparticles and possible solutionsJ Appl Toxicol201333101089109623408656
  • NriaguJZinc toxicity in humansEncyclopedia of Environmental Health2011801807
  • PlumLMRinkLHaaseHThe essential toxin: impact of zinc on human healthInt J Environ Res Public Health2010741342136520617034
  • Van CampenDRCopper interference with the intestinal absorption of zinc-65 by ratsJ Nutr19699711041085763434
  • FiskeDNMcCoyHEIIIKitchensCSZinc-induced sideroblastic anemia: report of a case, review of the literature, and description of the hematologic syndromeAm J Hematol19944621471508172183
  • SandsteadHHRequirements and toxicity of essential trace elements, illustrated by zinc and copperAm J Clin Nutr199561Suppl 3621s624s7879727
  • WangBFengWYWangTCAcute toxicity of nano- and micro-scale zinc powder in healthy adult miceToxicol Lett2006161211512316165331
  • WangBFengWWangMAcute toxicological impact of nano- and submicro-scaled zinc oxide powder on healthy adult miceJ Nanopart Res200810263276
  • KhanATGrahamTCOgdenLA two-generational reproductive toxicity study of zinc in ratsJ Environ Sci Health B200742440341517474020
  • GuoDBiHWuQWangDCuiYZinc oxide nanoparticles induce rat retinal ganglion cell damage through bcl-2, caspase-9 and caspase-12 pathwaysJ Nanosci Nanotechnol20131363769377723862406
  • GuoDBiHLiuBWuQWangDCuiYReactive oxygen species-induced cytotoxic effects of zinc oxide nanoparticles in rat retinal ganglion cellsToxicol In Vitro201327273173823232460
  • PaekHJLeeYJChungHEModulation of the pharmacokinetics of zinc oxide nanoparticles and their fates in vivoNanoscale2013523114161142723912904
  • SteuerHKrastevRLembertNMetallic oxide nanoparticles stimulate blood coagulation independent of their surface chargeJ Biomed Mater Res B Appl Biomater Epub12182013