References
- AbbottNJPatabendigeAADolmanDEYusofSRBegleyDJStructure and function of the blood–brain barrierNeurobiol Dis2010371132519664713
- TobiasAAhmedAMoonKSLesniakMSThe art of gene therapy for glioma: a review of the challenging road to the bedsideJ Neurol Neurosurg Psychiatry201384221322222993449
- AbbottNJBlood-brain barrier structure and function and the challenges for CNS drug deliveryJ Inherit Metab Dis201336343744923609350
- Pérez-MartínezFCGuerraJPosadasICeñaVBarriers to non-viral vector- mediated gene delivery in the nervous systemPharm Res20112881843185821225319
- HuangRMaHGuoYAngiopep-conjugated nanoparticles for targeted long-term gene therapy of Parkinson’s diseasePharm Res201330102549255923703371
- DemeuleMCurrieJCBertrandYInvolvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2J Neurochem200810641534154418489712
- DemeuleMRéginaAChéCIdentification and design of peptides as a new drug delivery system for the brainJ Pharmacol Exp Ther200832431064107218156463
- HuangSLiJHanLDual targeting effect of angiopep-2-modified, DNA-loaded nanoparticles for gliomaBiomaterials201132286832683821700333
- RenJShenSWangDThe targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2Biomaterials201233113324333322281423
- XinHShaXJiangXZhangWChenLFangXAnti-glioblastoma efficacy and safety of paclitaxel-loading angiopep-conjugated dual targeting PEG-PCL nanoparticlesBiomaterials201233328167817622889488
- WangJLuZWientjesMGAuJLDelivery of siRNA therapeutics: barriers and carriersAAPS J201012449250320544328
- Gomes-da-SilvaLCFonsecaNAMouraVPedroso de LimaMCSimõesSMoreiraJNLipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challengesAcc Chem Res20124571163117122568781
- SørensenDRLeirdalMSioudMGene silencing by systemic delivery of synthetic siRNAs in adult miceJ Mol Biol2003327476176612654261
- LiWSzokaFCLipid-based nanoparticles for nucleic acid deliveryPharm Res200724343844917252188
- SeniorJDelgadoCFisherDTilcockCGregoriadisGInfluence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: studies with poly(ethylene glycol)-coated vesiclesBiochim Biophys Acta19911062177821998713
- TorchilinVPOmelyanenkoVGPapisovMIPoly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevityBiochim Biophys Acta1994119511207918551
- HatakeyamaHAkitaHHarashimaHThe polyethyleneglycol dilemma: advantage and disadvantage of PEGylation of liposomes for systemic genes and nucleic acids delivery to tumorsBiol Pharm Bull201336689289923727912
- IshidaTKirchmeierMJMoaseEHZalipskySAllenTMTargeted delivery and triggered release of liposomal doxorubicin enhances cyto-toxicity against human B lymphoma cellsBiochim Biophys Acta20011515214415811718670
- KaleAATorchilinVPEnhanced transfection of tumor cells in vivo using “Smart” pH-sensitive TAT-modified pegylated liposomesJ Drug Target2007157–853854517671900
- XuHDengYChenDHongWLuYDongXEsterase-catalyzed dePEGylation of pH-sensitive vesicles modified with cleavable PEG-lipid derivativesJ Control Release2008130323824518657874
- ZhuLKatePTorchilinVPMatrix metalloprotease 2-responsive multifunctional liposomal nanocarrier for enhanced tumor targetingACS Nano2012643491349822409425
- AndresenTLThompsonDHKaasgaardTEnzyme-triggered nanomedicine: drug release strategies in cancer therapyMol Membr Biol201027735336320939771
- EgebladMWerbZNew functions for the matrix metalloproteinases in cancer progressionNat Rev Cancer20022316117411990853
- FujiwaraSNakagawaKHaradaHNagatoSIwataSOhnishiTSilencing hypoxia-inducible factor-1a inhibits cell migration and invasion under hypoxic environment in malignant gliomasInt J Oncol20073079380217332917
- GuGXiaHHuQPEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapyBiomaterials201334119620823069707
- HatakeyamaHAkitaHKogureKDevelopment of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipidGene Ther2007141687716915290
- TeradaTIwaiMKawakamiSYamashitaFHashidaMNovel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targetingJ Control Release2006111333334216488046
- RemautKLucasBBraeckmansKDemeesterJDe SmedtSCPegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotidesJ Control Release2007117225626617188777
- GjettingTJølckRAndresenTEffective nanoparticle based gene delivery by a protease triggered charge switchAdv Healthc Mater2014371107111824652709
- MillerCRBondurantBMcLeanSDMcGovernKAO’BrienDFLiposome-cell interactions in vitro: effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomesBiochemistry1998373712875128839737866
- JeffsLBPalmerLRAmbegiaEGGiesbrechtCEwanickSMacLachlanIA scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNAPharm Res200522336237215835741
- GjettingTArildsenNSChristensenCLIn vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfectionInt J Nanomedicine2010537138320957159
- SambrookJRusselDWMolecular Cloning: A Laboratory ManualNew York, NYCold Spring Harbor Laboratory Press2001
- KeWShaoKHuangRGene delivery targeted to the brain using an angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimerBiomaterials200930366976698519765819
- TurkBEHuangLLPiroETCantleyLCDetermination of protease cleavage site motifs using mixture-based oriented peptide librariesNat Biotechnol200119766166711433279
- OkadaYMorodomiTEnghildJJMatrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic propertiesEur J Biochem199019437217302269296
- LiuJJinXLiuKJLiuWMatrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stageJ Neurosci20123293044305722378877
- PuliSLaiJCBhushanAInhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavonesJ Neurooncol200679213514216598420
- ShaoKHuangRLiJAngiopep-2 modified PE-PEG based polymeric micelles for amphotericin B delivery targeted to the brainJ Control Release2010147111812620609375
- GaoHZhangSCaoSYangZPangZJiangXAngiopep-2 and activatable cell-penetrating peptide dual-functionalized nanoparticles for systemic glioma-targeting deliveryMol Pharm20141182755276324983928
- PulfordBReimNBellALiposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell culturesPLoS One201056e1108520559428
- ResnierPDavidSLautramNEGFR siRNA lipid nanocapsules efficiently transfect glioma cells in vitroInt J Pharm2013454274875523583841
- MalmoJSandvigAVårumKMStrandSPNanoparticle mediated P-glycoprotein silencing for improved drug delivery across the blood-brain barrier: a siRNA-chitosan approachPLoS One201381e5418223372682
- EnginKLeeperDBCaterJRThistlethwaiteAJTupchongLMcFarlaneJDExtracellular pH distribution in human tumoursInt J Hyperthermia19951122112167790735
- LeeESNaKBaeYHPolymeric micelle for tumor pH and folate-mediated targetingJ Control Release2003911–210311312932642
- JinJBaeKHYangHIn vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticlesBioconjug Chem201122122568257222070554
- CartellieriMHendruschkSWiedemuthRRNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivoNeuro Oncol201113101074108921788344
- RosenbergGAMatrix metalloproteinases and their multiple roles in neurodegenerative diseasesLancet Neurol20098220521619161911
- JinRYangGLiGMolecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activatorNeurobiol Dis201038337638520302940
- MahajanSDAalinkeelRReynoldsJLSuppression of MMP-9 expression in brain microvascular endothelial cells (BMVEC) using a gold nanorod (GNR)-siRNA nanoplexImmunol Invest201241433735521864113
- ZhangGFahmyRGDiGirolamoNKhachigianLMJUN siRNA regulates matrix metalloproteinase-2 expression, microvascular endothelial growth and retinal neovascularisationJ Cell Sci2006119153219322616847049
- BonoiuAMahajanSDYeLMMP-9 gene silencing by a quantum dot-siRNA nanoplex delivery to maintain the integrity of the blood brain barrierBrain Res2009128214215519477169