Microvascular pericytes in healthy and diseased kidneys

References

• LinSLKisselevaTBrennerDADuffieldJSPericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidneyAm J Pathol200817361617162719008372
   PubMed Web of Science ®Google Scholar
• ChangFCChouYHChenYTLinSLNovel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosisJ Formos Med Assoc20121111158959823217594
   PubMed Web of Science ®Google Scholar
• Díaz-FloresLGutiérrezRMadridJFPericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell nicheHistol Histopathol200924790996919475537
   PubMed Web of Science ®Google Scholar
• KaisslingBLe HirMThe renal cortical interstitium: morphological and functional aspectsHistochem Cell Biol2008130224726218575881
   PubMed Web of Science ®Google Scholar
• HumphreysBDLinSLKobayashiAFate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosisAm J Pathol20101761859720008127
   PubMed Web of Science ®Google Scholar
• CampanholleGLigrestiGGharibSADuffieldJSCellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosisAm J Physiol Cell Physiol20133047C591C60323325411
   PubMed Web of Science ®Google Scholar
• Wilkinson-BerkaJLBabicSDe GooyerTInhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathyAm J Pathol200416441263127315039215
   PubMed Web of Science ®Google Scholar
• RojasAChangFCLinSLDuffieldJSThe role played by perivascular cells in kidney interstitial injuryClin Nephrol201277540040822551886
   PubMed Web of Science ®Google Scholar
• WuCFChiangWCLaiCFTransforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosisAm J Pathol2013182111813123142380
   PubMed Web of Science ®Google Scholar
• PicardNBaumOVogetsederAKaisslingBLe HirMOrigin of renal myofibroblasts in the model of unilateral ureter obstruction in the ratHistochem Cell Biol2008130114115518449560
   PubMed Web of Science ®Google Scholar
• AsadaNTakaseMNakamuraJDysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in miceJ Clin Invest2011121103981399021911936
   PubMed Web of Science ®Google Scholar
• FaulknerJLSzcykalskiLMSpringerFBarnesJLOrigin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosisAm J Pathol200516751193120516251405
   PubMed Web of Science ®Google Scholar
• BieleszBSirinYSiHEpithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humansJ Clin Invest2010120114040405420978353
   PubMed Web of Science ®Google Scholar
• SoumaTYamazakiSMoriguchiTPlasticity of renal erythropoietin-producing cells governs fibrosisJ Am Soc Nephrol201324101599161623833259
   PubMed Web of Science ®Google Scholar
• BoorPOstendorfTFloegeJRenal fibrosis: novel insights into mechanisms and therapeutic targetsNat Rev Nephrol201061164365620838416
   PubMed Web of Science ®Google Scholar
• KlingbergFHinzBWhiteESThe myofibroblast matrix: implications for tissue repair and fibrosisJ Pathol2013229229830922996908
   PubMed Web of Science ®Google Scholar
• IwanoMPliethDDanoffTMXueCOkadaHNeilsonEGEvidence that fibroblasts derive from epithelium during tissue fibrosisJ Clin Invest2002110334135012163453
   PubMed Web of Science ®Google Scholar
• InoueTPliethDVenkovCDXuCNeilsonEGAntibodies against macrophages that overlap in specificity with fibroblastsKidney Int20056762488249315882296
   PubMed Web of Science ®Google Scholar
• ÖsterreicherCHPenz-ÖsterreicherMGrivennikovSIFibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liverProc Natl Acad Sci U S A2011108130831321173249
   PubMed Web of Science ®Google Scholar
• KoestersRKaisslingBLehirMTubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cellsAm J Pathol2010177263264320616344
   PubMed Web of Science ®Google Scholar
• LiLZepeda-OrozcoDBlackRLinFAutophagy is a component of epithelial cell fate in obstructive uropathyAm J Pathol201017641767177820150430
   PubMed Web of Science ®Google Scholar
• GöritzCDiasDOTomilinNBarbacidMShupliakovOFrisénJA pericyte origin of spinal cord scar tissueScience2011333603923824221737741
   PubMed Web of Science ®Google Scholar
• DulauroySDi CarloSELangaFEberlGPedutoLLineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injuryNat Med20121881262127022842476
   PubMed Web of Science ®Google Scholar
• HungCLinnGChowYHRole of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosisAm J Respir Crit Care Med2013188782083023924232
   PubMed Web of Science ®Google Scholar
• KisselevaTCongMPaikYMyofibroblasts revert to an inactive phenotype during regression of liver fibrosisProc Natl Acad Sci U S A2012109249448945322566629
   PubMed Web of Science ®Google Scholar
• DirekzeNCForbesSJBrittanMMultiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted miceStem Cells200321551452012968105
   PubMed Web of Science ®Google Scholar
• DuffieldJSParkKMHsiaoLLRestoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cellsJ Clin Invest200511571743175516007251
   PubMed Web of Science ®Google Scholar
• LeBleuVSTaduriGO’ConnellJOrigin and function of myofibroblasts in kidney fibrosisNat Med20131981047105323817022
   PubMed Web of Science ®Google Scholar
• LeYZZhengLZhengWMouse opsin promoter-directed Cre recombinase expression in transgenic miceMol Vis20061238939816636658
   PubMed Web of Science ®Google Scholar
• FloegeJEitnerFAlpersCEA new look at platelet-derived growth factor in renal diseaseJ Am Soc Nephrol2008191122318077793
   PubMed Web of Science ®Google Scholar
• EddyAALópez-GuisaJMOkamuraDMYamaguchiIInvestigating mechanisms of chronic kidney disease in mouse modelsPediatr Nephrol20122781233124721695449
   PubMed Web of Science ®Google Scholar
• EddyAAThe origin of scar-forming kidney myofibroblastsNat Med201319896496623921738
   PubMed Web of Science ®Google Scholar
• ChenYTChangFCWuCFPlatelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosisKidney Int201180111170118121716259
   PubMed Web of Science ®Google Scholar
• DarlandDCMassinghamLJSmithSRPiekESaint-GeniezMD’AmorePAPericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survivalDev Biol2003264127528814623248
   PubMed Web of Science ®Google Scholar
• EvensenLMicklemDRBloisAMural cell associated VEGF is required for organotypic vessel formationPLoS One200946e579819495422
   PubMed Web of Science ®Google Scholar
• PerrinRMKonopatskayaOQiuYHarperSBatesDOChurchillAJDiabetic retinopathy is associated with a switch in splicing from anti-to pro-angiogenic isoforms of vascular endothelial growth factorDiabetologia200548112422242716193288
   PubMed Web of Science ®Google Scholar
• GrunsteinJMasbadJJHickeyRGiordanoFJohnsonRSIsoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculatureMol Cell Biol200020197282729110982845
   PubMed Web of Science ®Google Scholar
• LinSLChangFCSchrimpfCTargeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosisAm J Pathol2011178291192321281822
   PubMed Web of Science ®Google Scholar
• EreminaVJeffersonJAKowalewskaJVEGF inhibition and renal thrombotic microangiopathyN Engl J Med2008358111129113618337603
   PubMed Web of Science ®Google Scholar
• HakroushSMoellerMJTheiligFEffects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular diseaseAm J Pathol200917551883189519834063
   PubMed Web of Science ®Google Scholar
• BlobeGCSchiemannWPLodishHFRole of transforming growth factor beta in human diseaseN Engl J Med2000342181350135810793168
   PubMed Web of Science ®Google Scholar
• YanagitaMInhibitors/antagonists of TGF-β system in kidney fibrosisNephrol Dial Transplant201227103686369123114895
   PubMed Web of Science ®Google Scholar
• FukudaKYoshitomiKYanagidaTTokumotoMHirakataHQuantification of TGF-beta1 mRNA along rat nephron in obstructive nephropathyAm J Physiol Renal Physiol20012813F513F52111502600
   PubMed Web of Science ®Google Scholar
• SatoMMuragakiYSaikaSRobertsABOoshimaATargeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstructionJ Clin Invest2003112101486149414617750
   PubMed Web of Science ®Google Scholar
• YangLBesschetnovaTYBrooksCRShahJVBonventreJVEpithelial cell cycle arrest in G2/M mediates kidney fibrosis after injuryNat Med2010165535543 1p following 14320436483
   PubMed Web of Science ®Google Scholar
• DiRoccoDPKobayashiATaketoMMMcMahonAPHumphreysBDWnt4/β-catenin signaling in medullary kidney myofibroblastsJ Am Soc Nephrol20132491399141223766539
   PubMed Web of Science ®Google Scholar
• RenSJohnsonBGKidaYLRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1Proc Natl Acad Sci U S A201311041440144523302695
   PubMed Web of Science ®Google Scholar
• LindahlPJohanssonBRLevéenPBetsholtzCPericyte loss and microaneurysm formation in PDGF-B-deficient miceScience199727753232422459211853
   PubMed Web of Science ®Google Scholar
• ArmulikAGenovéGMäeMPericytes regulate the blood-brain barrierNature2010468732355756120944627
   PubMed Web of Science ®Google Scholar
• AntonettiDAKleinRGardnerTWDiabetic retinopathyN Engl J Med2012366131227123922455417
   PubMed Web of Science ®Google Scholar
• GreenbergJIShieldsDJBarillasSGA role for VEGF as a negative regulator of pericyte function and vessel maturationNature2008456722380981318997771
   PubMed Web of Science ®Google Scholar
• StalmansINgYSRohanRArteriolar and venular patterning in retinas of mice selectively expressing VEGF isoformsJ Clin Invest2002109332733611827992
   PubMed Web of Science ®Google Scholar
• SchrimpfCXinCCampanholleGPericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injuryJ Am Soc Nephrol201223586888322383695
   PubMed Web of Science ®Google Scholar
• GeretySSWangHUChenZFAndersonDJSymmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular developmentMol Cell19994340341410518221
   PubMed Web of Science ®Google Scholar
• KidaYIeronimakisNSchrimpfCReyesMDuffieldJSEphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injuryJ Am Soc Nephrol201324455957223492730
   PubMed Web of Science ®Google Scholar
• GruberMHuCJJohnsonRSBrownEJKeithBSimonMCAcute postnatal ablation of Hif-2alpha results in anemiaProc Natl Acad Sci U S A200710472301230617284606
   PubMed Web of Science ®Google Scholar
• HaaseVHRegulation of erythropoiesis by hypoxia-inducible factorsBlood Rev2013271415323291219
   PubMed Web of Science ®Google Scholar
• FehrTAmmannPGarzoniDInterpretation of erythropoietin levels in patients with various degrees of renal insufficiency and anemiaKidney Int20046631206121115327419
   PubMed Web of Science ®Google Scholar
• HungSCLinYPTarngDCErythropoiesis-stimulating agents in chronic kidney disease: What have we learned in 25 years?J Formos Med Assoc Epub9302013
   Web of Science ®Google Scholar
• ObaraNSuzukiNKimKNagasawaTImagawaSYamamotoMRepression via the GATA box is essential for tissue-specific erythropoietin gene expressionBlood2008111105223523218202227
   PubMed Web of Science ®Google Scholar
• PaliegeARosenbergerCBondkeAHypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilizationKidney Int201077431231820016470
   PubMed Web of Science ®Google Scholar
• BernhardtWMWiesenerMSScigallaPInhibition of prolyl hydroxylases increases erythropoietin production in ESRDJ Am Soc Nephrol201021122151215621115615
   PubMed Web of Science ®Google Scholar
• BechtelWMcGoohanSZeisbergEMMethylation determines fibroblast activation and fibrogenesis in the kidneyNat Med201016554455020418885
   PubMed Web of Science ®Google Scholar
• ChangYTPanSYLinSLSeeking for a way to revive erythropoietin production in chronic kidney diseaseJ Formos Med Assoc20131121165765823669141
   PubMed Web of Science ®Google Scholar
• PanSYChangYTLinSLThe role of hypoxia-inducible factors in renal fibrosisJ Formos Med Assoc20131121058758824120150
   PubMed Web of Science ®Google Scholar