Hypomagnesemia: a clinical perspective

References

• SandersGTHuijenHJSandersRMagnesium in disease: a review with special emphasis on the serum ionized magnesiumClin Chem Lab Med19993711–121011103310726809
   PubMed Web of Science ®Google Scholar
• SarisNEMervaalaEKarppanenHKhawajaJALewenstamAMagnesium: an update on physiological, clinical and analytical aspectsClin Chim Acta20002941–212610727669
   PubMed Web of Science ®Google Scholar
• SwaminathanRMagnesium metabolism and its disordersClin Biochem Rev2003242476618568054
   PubMedGoogle Scholar
• FlinkEBMagnesium deficiency: etiology and clinical spectrumActa Med Scand Suppl19816471251377020347
   PubMedGoogle Scholar
• Jahnen-DechentWKettelerMMagnesium basicsClin Kidney J20125Suppl 1i3i14
   PubMedGoogle Scholar
• SchwartzRSpencerHWelshJJMagnesium absorption in human subjects from leafy vegetables, intrinsically labeled with stable 26 MgAm J Clin Nutr19843945715766711467
   PubMed Web of Science ®Google Scholar
• FineKDSanta AnaCAPorterJLFordtranJSIntestinal absorption of magnesium from food and supplementsJ Clin Invest19918823964021864954
   PubMed Web of Science ®Google Scholar
• QuammeGARecent developments in intestinal magnesium absorptionCur Opin Gastroenterol2008242230235
   Web of Science ®Google Scholar
• SchweigelMMartensHMagnesium transport in the gastrointestinal tractFront Biosci20005D666D67710922297
   PubMed Web of Science ®Google Scholar
• SchlingmannKPGudermannTA critical role of TRPM channel-kinase for human magnesium transportJ Physiol2005566Pt 230130815845589
   PubMed Web of Science ®Google Scholar
• SchlingmannKPWeberSPetersMHypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene familyNat Genet200231216617012032568
   PubMed Web of Science ®Google Scholar
• [no authors listed]Plasma and bone magnesiumNutrition Reviews196018721421613858038
   PubMed Web of Science ®Google Scholar
• QuammeGADirksJHThe physiology of renal magnesium handlingRen Physiol1986952572693544106
   PubMedGoogle Scholar
• QuammeGAControl of magnesium transport in the thick ascending limbAm J Physiol19892562 Pt 2F197F2102644845
   PubMed Web of Science ®Google Scholar
• BlanchardAJeunemaitreXCoudolPParacellin-1 is critical for magnesium and calcium reabsorption in the human thick ascending limb of HenleKidney Int20015962206221511380823
   PubMed Web of Science ®Google Scholar
• WeberSSchneiderLPetersMNovel paracellin-1 mutations in 25 families with familial hypomagnesemia with hypercalciuria and nephrocalcinosisJ Am Soc Nephrol20011291872188111518780
   PubMed Web of Science ®Google Scholar
• KonradMSchallerASeelowDMutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvementAm J Hum Genet200679594995717033971
   PubMed Web of Science ®Google Scholar
• HouJGoodenoughDAClaudin-16 and claudin-19 function in the thick ascending limbCurr Opin Nephrol Hypertens201019548348820616717
   PubMed Web of Science ®Google Scholar
• VoetsTNiliusBHoefsSTRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorptionJ Biol Chem20042791192514576148
   PubMed Web of Science ®Google Scholar
• KonradMSchlingmannKPGudermanTInsights into the molecular nature of magnesium homeostasisAm J Physiol Renal Physiol20042864F599F60515001450
   PubMed Web of Science ®Google Scholar
• ReilyRFEllisonDHMammalian distal tubule: physiology, pathophysiology, and molecular anatomyPhysiol Rev200080127731310617770
   PubMed Web of Science ®Google Scholar
• LemminkHHKnoersNVKárolyiLNovel mutations in the thiazide-sensitive NaCl cotransporter gene in patients with Gitelman syndrome with predominant localization to the C-terminal domainKidney Int19985437207309734597
   PubMed Web of Science ®Google Scholar
• NijenhuisTVallonVvan der KempAWLoffingJHoenderopJGBindelsRJEnhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemiaJ Clin Invest200511561651165815902302
   PubMed Web of Science ®Google Scholar
• YogiACalleraGEO’ConnorSEDysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemiaJ Hypertens20112971400141021602712
   PubMed Web of Science ®Google Scholar
• GlaudemansBvan der WijstJScolaRHA missense mutation in the Kv1.1 voltage-gated potassium channel-encoding gene KCNA1 is linked to human autosomal dominant hypomagnesemiaJ Clin Invest2009119493694219307729
   PubMed Web of Science ®Google Scholar
• GroenestegeWMThébaultSvan der WijstJImpaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemiaJ Clin Invest200711782260226717671655
   PubMed Web of Science ®Google Scholar
• ThebaultSAlexanderRTTiel GroenestegeWMHoenderopJGBindelsRJEGF increases TRPM6 activity and surface expressionJ Am Soc Nephrol2009201788519073827
   PubMed Web of Science ®Google Scholar
• MeijICKoenderinkJBvan BokhovenHDominant isolated renal magnesium loss is caused by misrouting of the Na(+), (K+)-ATPase gamma-subunitNat Genet200026326526611062458
   PubMed Web of Science ®Google Scholar
• ArystarkhovaESweadnerKJSplice variants of the gamma subunit (FXYD2) and their significance in regulation of the Na, K-ATPase in kidneyJ Bioenerg Biomembr200537638138616691469
   PubMed Web of Science ®Google Scholar
• FerrèSVeenstraGJBouwmeesterRHoenderopJGBindelsRJHNF-1B specifically regulates the transcription of the gamma a-subunit of the Na+/K+-ATPaseBiochem Biophys Res Commun2011404128429021130072
   PubMed Web of Science ®Google Scholar
• Kolatsi-JoannouMBinghamCEllardSHepatocyte nuclear factor-1 beta: a new kindred with renal cysts and diabetes and gene expression in normal human developmentJ Am Soc Nephrol200112102175218011562418
   PubMed Web of Science ®Google Scholar
• SchollUIChoiMLiuTSeizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10Proc Natl Acad Sci U S A2009106145842584719289823
   PubMed Web of Science ®Google Scholar
• BockenhauerDFeatherSStanescuHCEpilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ 10 mutationsN Engl J Med2009360191960197019420365
   PubMed Web of Science ®Google Scholar
• PaulaisMBloch-FaureMPicardNRenal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSame/EAST syndromeProc Natl Acad Sci U S A201110825103611036621633011
   PubMed Web of Science ®Google Scholar
• ChaSKHuangCDingYQiXHuangCLMillerRTCalcium-sensing receptor decreases cell surface expression of the inwardly rectifying K+ channel Kir4.1J Biol Chem201128631828183521084311
   PubMed Web of Science ®Google Scholar
• StuiverMLainezSWillCCNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemiaAm J Hum Genet201188333334321397062
   PubMed Web of Science ®Google Scholar
• SongYHsuYHNiuTMansonJEBuringJELiuSCommon genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in womenBMC Med Genet200910419149903
   PubMed Web of Science ®Google Scholar
• GroenestegeWMHoenderopJGvan den HeuvelLKnoersNBindelsRJThe epithelial Mg2+ channel transient receptor potential melastatin 6 is regulated by dietary Mg2+ content and estrogensJ Am Soc Nephrol20061741035104316524949
   PubMed Web of Science ®Google Scholar
• BarrCSLangCCHansonJArnottMKennedyNStruthersADEffects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery diseaseAm J Cardiol19957617125912657503007
   PubMed Web of Science ®Google Scholar
• GaoXPengLAdhikariCMLinJZuoZSpironolactone reduced arrhythmia and maintained magnesium homeostasis in patients with congestive heart failureJ Cardiac Fail2007133170177
   PubMed Web of Science ®Google Scholar
• SontiaBMontezanoACParaviciniTTabetFTouyzRMDownregulation of renal TRMP7 and increased inflammation and fibrosis in aldosterone-infused mice: effects of magnesiumHypertension200851491592118268139
   PubMed Web of Science ®Google Scholar
• MacIntyreIRobinsonCJMagnesium and the gut: experimental and clinical observationsAnn N Y Acad Sci196916228658735259576
   PubMed Web of Science ®Google Scholar
• HershTSiddiquiDAMagnesium and the pancreasAm J of Clin Nutr19732633623664570229
   PubMed Web of Science ®Google Scholar
• AgusZSHypomagnesemiaJ Am Soc Nephrol19991071616162210405219
   PubMed Web of Science ®Google Scholar
• ElisafMMerkouropoulosMTsianosEVSiamopoulosKCPathogenetic mechanisms of hypomagnesemia in alcoholic patientsJ Trace Elem Med Biol1995942102148808192
   PubMed Web of Science ®Google Scholar
• TambyahPARauffALeeKOPersistent hypomagnesaemia following parathyroid surgery, hypermagnesuria as a possible causeAnn Acad Med Singapore19901945365392221815
   PubMedGoogle Scholar
• WeiselbergECGonzalezMFisherMEating disorders in the twenty-first centuryMinerva Ginecol201163653154522036757
   PubMedGoogle Scholar
• FrazierTGMuchaMERushIHTrullEJCarlsonSAO’ConnorJAHypomagnesemia: higher risk using total parenteral nutrition in the treatment of patients with malignanciesJ Surg Oncol198013135386766197
   PubMed Web of Science ®Google Scholar
• FlinkEBMagnesium deficiency. Etiology and clinical spectrumActa Med Scand Suppl19816471251377020347
   PubMedGoogle Scholar
• HoKMLeonardARisk factors and outcome associated with hypomagnesemia in massive transfusionTransfusion201151227027620735766
   PubMed Web of Science ®Google Scholar
• AglioLSStanfordGGMaddiRBoydJL3rdNussbaumSChernowBHypomagnesemia is common following cardiac surgeryJ Cardiothorac Vasc Anesth1991532012081863738
   PubMedGoogle Scholar
• GearhartMOSorgTBFoscarnet-induced severe hypomagnesemia and other electrolyte disordersAnn Pharmacother19932732852898384030
   PubMed Web of Science ®Google Scholar
• PhamPCTPhamPMTPhamSVMillerJMPhamPTTHypomagnesemia in patients with type 2 diabetesClin J Am Soc Nephrol20072236637317699436
   PubMed Web of Science ®Google Scholar
• ShahGMAlvaradoPKirschenbaumMASymptomatic hypocalcemia and hypomagnesemia with renal magnesium wasting associated with pentamidine therapy in a patient with AIDSAm J Med19908933803822393042
   PubMed Web of Science ®Google Scholar
• LeeCTLienYHHLaiLWNgHYChiouTTChenHCVariations of dietary salt and fluid modulate calcium and magnesium transport in the renal distal tubuleNephron Physiol20121223–4192723774784
   PubMedGoogle Scholar
• HolmesAMHeslingCMWilsonTMDrug-induced secondary hyperaldosteronism in patients with pulmonary tuberculosisQ J Med1970391542993155449594
   PubMedGoogle Scholar
• ChouCLChenYHChauTLinSHAcquired Bartter-like syndrome associated with gentamicin administrationAm J Med Sci2005329314414915767821
   PubMed Web of Science ®Google Scholar
• ZietseRZoutendijkRHoornEJFluid, electrolyte and acid-base disorders associated with antibiotic therapyNat Rev Nephrol20095419320219322184
   PubMed Web of Science ®Google Scholar
• LedeganckKJBouletGAHorvathCAEffects of renal distal tubule transporters TRPM6 and NCC in a rat model of cyclosporine nephrotoxicity and effect of EGF treatmentAm J Physiol Renal Physiol20113013F486F49321653632
   PubMed Web of Science ®Google Scholar
• NijenhuisTHoenderopJGBindelsRJDownregulation of Ca(2+) and Mg(2+) transport proteins in the kidney explains tacrolimus (FK506)-induced hypercalciuria and hypomagnesemiaJ Am Soc Nephrol200415354955714978156
   PubMed Web of Science ®Google Scholar
• IkariAOkudeCSawadaHTakahashiTSugataniJMiwaMDown-regulation of TRPM6-mediated magnesium influx by cyclosporin ANaunyn Schmiedebergs Arch Pharmacol20083774–633334318026717
   PubMed Web of Science ®Google Scholar
• AisaYMoriTNakazatoTEffects of immunosuppressive agents on magnesium metabolism early after allogeneic hematopoietic stem cell transplantationTransplantation20058081046105016278584
   PubMed Web of Science ®Google Scholar
• IkariASanadaASawadaHOkudeCTonegawaCSugataniJDecrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular eptiherlial cellsBiochim Biophys Acta2011180861502150821073857
   PubMed Web of Science ®Google Scholar
• da SilvaCAde BragançaACShimizuMHRosiglitazone prevents sirolimus-induced hypomagnesemia, hypokalemia, and downregulation of NKCC2 protein expressionAm J Physiol Renal Physiol20092974F916F92219656910
   PubMed Web of Science ®Google Scholar
• Sánchez-FructuosoAISantín CanteroJMPérez FloresIValero San CecilioRCalvo RomeroNVilalta CasasRChanges in magnesium and potassium homeostasis after conversion from a calcineurin inhibitor regimen to an mTOR inhibitor-based regimenTransplant Proc20104283047304920970606
   PubMed Web of Science ®Google Scholar
• NijenhuisTRenkemaKYHoenderopJGBindelsRJAcid-base status determines the renal expression of Ca2+ and Mg2+ transport proteinsJ Am Soc Nephrol200617361762616421227
   PubMed Web of Science ®Google Scholar
• ZaikaOLMamenkoMPalyginOBoukelmouneNStaruschenkoAPochynyukODirect inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamineAm J Physiol Renal Physiol20133059F1277F128723986512
   PubMed Web of Science ®Google Scholar
• SrivastavaRAslamMKalluriSRPotassium channel KIR4.1 as an immune target in multiple sclerosisN Engl J Med2012367211512322784115
   PubMed Web of Science ®Google Scholar
• LoffingJLoffing-CueniDHegylIThiazide treatment of rats provokes apoptosis in distal tubule cellsKidney Int1996504118011908887276
   PubMed Web of Science ®Google Scholar
• Younes-IbrahimMBarneseMBurthPCastro-FariaMVInhibition of purified human kidney Na+-K+-ATPase by cyclosporine A: a possible mechanism for drug human nephrotoxicityAnn N Y Acad Sci200398663363512763906
   PubMed Web of Science ®Google Scholar
• RodrigoRThielemannLEffects of chronic and acute ethanol exposure on renal (Na+K)-ATPase in the ratGen Pharmacol19972957197239347316
   PubMedGoogle Scholar
• do Pazo-OubiñaFEstefanell-TejeroARiu-ViladomsGAnglada-MartínezHMolas-FerrerGCreus-BaróNMagnesium monitoring practice in monoclonal anti-epidermal growth factor receptor antibodies therapyJ Clin Pharma Ther2013382101103
   Web of Science ®Google Scholar
• LedeganckKJBouletGABogersJJVerpootenGADe WinterBYThe TRPM6/EGF pathway is downregulated in a rat model of cisplatin nephrotoxicityPLoS One201382e5701623457647
   PubMed Web of Science ®Google Scholar
• ChrispalABooruguHPrabhakarATMosesVAmikacin-induced type 5 Bartter-like syndrome with severe hypocalcemiaJ Postgrad Med200955320821019884751
   PubMed Web of Science ®Google Scholar
• ChouCLChenYHChauTLinSHAcquired Bartter-like syndrome associated with gentamicin administrationAm J Med Sci2005329314414915767821
   PubMed Web of Science ®Google Scholar
• RasmussenAQJørgensenNRSchwarzPClinical and biochemical outcomes of cinacalcet treatment of familial hypocalciuric hypercalcemia: a case seriesJ Med Case Rep20115156422142470
   PubMedGoogle Scholar
• NairAVHocherBVerkaartSLoss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancyProc Natl Acad Sci U S A201210928113241132922733750
   PubMed Web of Science ®Google Scholar
• FinkelsteinAHolzRAqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin BMembranes197323774084585230
   PubMedGoogle Scholar
• CunninghamJJAnbarRDCrawfordJDHypomagnesemia: a multifactorial complication of treatment of patients with severe burn traumaJPEN J Parenter Enteral Nutr19871143643673112426
   PubMed Web of Science ®Google Scholar
• ElisafMPanteliKTheodorouJSiamopoulosKCFractional excretion of magnesium in normal subjects and in patients with hypomagnesemiaMagnes Res19971043153209513927
   PubMed Web of Science ®Google Scholar
• PhamPCPhamPMPhamPALower serum magnesium levels are associated with more rapid decline of renal function in patients with diabetes mellitus type 2Clin Nephrol200563642943615960144
   PubMed Web of Science ®Google Scholar
• Van LaeckeSVan BiesenWVanholderRHypomagnesaemia, the kidney and the vesselsNephrol Dial Transplant201227114003401022610987
   PubMed Web of Science ®Google Scholar
• US Department of Health and Human Services. National Institutes of HealthMagnesium fact sheet for health professionals Available from ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/#h3Accessed March 27, 2014
   Google Scholar