Nonlinear Relationship Between Maternal and Cord Blood Vitamin B₁₂ and Folate from a Chinese Population-Based Study

References

• Liu C, Liu C, Wang Q, Zhang Z. Supplementation of folic acid in pregnancy and the risk of preeclampsia and gestational hypertension: a meta-analysis. Arch Gynecol Obstet. 2018;298(4):697–704. doi:10.1007/s00404-018-4823-4
   PubMed Web of Science ®Google Scholar
• Liu X, Lv L, Zhang H, et al. Folic acid supplementation, dietary folate intake and risk of preterm birth in China. Eur J Nutr. 2016;55(4):1411–1422. doi:10.1007/s00394-015-0959-1
   PubMed Web of Science ®Google Scholar
• Caffrey A, McNulty H, Irwin RE, Walsh CP, Pentieva K. Maternal folate nutrition and offspring health: evidence and current controversies. Proc Nutr Soc. 2018;78(2):208–220. doi:10.1017/S0029665118002689
   PubMed Web of Science ®Google Scholar
• Estevez-Ordonez D, Davis MC, Hopson B, et al. Reducing inequities in preventable neural tube defects: the critical and underutilized role of neurosurgical advocacy for folate fortification. Neurosurg Focus. 2018;45(4):E20. doi:10.3171/2018.7.FOCUS18231
   PubMed Web of Science ®Google Scholar
• Laharwal MA, Sarmast AH, Ramzan AU, et al. Epidemiology of the neural tube defects in Kashmir Valley. J Pediatr Neurosci. 2016;11(3):213–218. doi:10.4103/1817-1745.193368
   PubMedGoogle Scholar
• Stover PJ. Physiology of folate and vitamin B12 in health and disease. Nutr Rev. 2004;62(6 Pt 2):S3–S12; discussion S13. doi:10.1111/j.1753-4887.2004.tb00070.x
   PubMed Web of Science ®Google Scholar
• Thompson MD, Cole DE, Ray JG. Vitamin B-12 and neural tube defects: the Canadian experience. Am J Clin Nutr. 2009;89(2):697S–701S. doi:10.3945/ajcn.2008.26947B
   PubMed Web of Science ®Google Scholar
• Peker E, Demire N, Tuncer O, et al. The levels of vitamin B12, folate and homocysteine in mothers and their babies with neural tube defects. J Matern Fetal Neonatal Med. 2016;29(18):2944–2948. doi:10.3109/14767058.2015.1109620
   PubMed Web of Science ®Google Scholar
• Salcedo-Bellido I, Martinez-Galiano JM, Olmedo-Requena R, et al. Association between vitamin intake during pregnancy and risk of small for gestational age. Nutrients. 2017;9(12):1277. doi:10.3390/nu9121277
   PubMed Web of Science ®Google Scholar
• Senousy SM, Farag MK, Gouda AS, El Noury MA, Dabbous OA, Gaber KR. Association between biomarkers of vitamin B12 status and the risk of neural tube defects. J Obstet Gynaecol Res. 2018;44(10):1902–1908. doi:10.1111/jog.13751
   PubMed Web of Science ®Google Scholar
• McLean E, de Benoist B, Allen LH. Review of the magnitude of folate and vitamin B12 deficiencies worldwide. Food Nutr Bul. 2008;29(2 Suppl):S38–S51. doi:10.1177/15648265080292S107
   PubMed Web of Science ®Google Scholar
• Sukumar N, Rafnsson SB, Kandala NB, Bhopal R, Yajnik CS, Saravanan P. Prevalence of vitamin B-12 insufficiency during pregnancy and its effect on offspring birth weight: a systematic review and meta-analysis. Am J Clin Nutr. 2016;103(5):1232–1251. doi:10.3945/ajcn.115.123083
   PubMed Web of Science ®Google Scholar
• Adaikalakoteswari A, Vatish M, Lawson A, et al. Low maternal vitamin B12 status is associated with lower cord blood HDL cholesterol in white Caucasians living in the UK. Nutrients. 2015;7(4):2401–2414. doi:10.3390/nu7042401
   PubMed Web of Science ®Google Scholar
• Ahn HS. Relation between folate levels of maternal-umbilical cord blood, placenta tissue and pregnancy outcomes. J Community Nutr. 2004;6(2):91–96.
   Google Scholar
• Molloy AM, Mills JL, McPartlin J, Kirke PN, Scott JM, Daly S. Maternal and fetal plasma homocysteine concentrations at birth: the influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C–>T variant. Am J Obstet Gynecol. 2002;186(3):499–503. doi:10.1067/mob.2002.121105
   PubMed Web of Science ®Google Scholar
• Hao L, Ma J, Zhu J, et al. High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status. J Nutr. 2007;137(2):407–413. doi:10.1093/jn/137.2.407
   PubMed Web of Science ®Google Scholar
• Dang S, Yan H, Zeng L, et al. The status of vitamin B12 and folate among Chinese women: a population-based cross-sectional study in northwest China. PLoS One. 2014;9(11):e112586. doi:10.1371/journal.pone.0112586
   PubMed Web of Science ®Google Scholar
• Yang J, Kang Y, Cheng Y, Zeng L, Yan H, Dang S. Maternal dietary patterns during pregnancy and congenital heart defects: a Case-Control Study. Int J Environ Res Public Health. 2019;16(16):2957. doi:10.3390/ijperph16162957
   PubMed Web of Science ®Google Scholar
• Allen LH. Folate and vitamin B12 status in the Americas. Nutr Rev. 2004;62(6 Pt 2):S29–S33; discussion S34. doi:10.1111/j.1753-4887.2004.tb00069.x
   PubMed Web of Science ®Google Scholar
• Miliku K, Mesu A, Franco OH, Hofman A, Steegers EAP, Jaddoe VWV. Maternal and fetal folate, vitamin B12, and homocysteine concentrations and childhood kidney outcomes. Am J Kidney Dis. 2017;69(4):521–530. doi:10.1053/j.ajkd.2016.11.014
   PubMed Web of Science ®Google Scholar
• Yang J, Dang S, Cheng Y, et al. Dietary intakes and dietary patterns among pregnant women in Northwest China. Public Health Nutr. 2017;20(2):282–293. doi:10.1017/S1368980016002159
   PubMed Web of Science ®Google Scholar
• Ling B, Tang J, Kong F, Mitcham EJ, Wang S. Kinetics of food quality changes during thermal processing: a review. Food Bioprocess Technol. 2015;8(2):343–358. doi:10.1007/s11947-014-1398-3
   Web of Science ®Google Scholar
• Oghbaei M, Prakash J. Effect of compositional alteration of food matrices and processing on availability of selected nutrients and bioactive components in rice products. Int J Food Sci Nutr. 2011;62(3):250–261. doi:10.3109/09637486.2010.527322
   PubMed Web of Science ®Google Scholar
• van Boekel M, Fogliano V, Pellegrini N, et al. A review on the beneficial aspects of food processing. Mol Nutr Food Res. 2010;54(9):1215–1247. doi:10.1002/mnfr.200900608
   PubMed Web of Science ®Google Scholar
• Guerra-Shinohara EM, Morita OE, Peres S, et al. Low ratio of S-adenosylmethionine to S-adenosylhomocysteine is associated with vitamin deficiency in Brazilian pregnant women and newborns. Am J Clin Nutr. 2004;80(5):1312–1321. doi:10.1093/ajcn/80.5.1312
   PubMed Web of Science ®Google Scholar
• Cianciolo G, De Pascalis A, Di Lullo L, Ronco C, Zannini C, La Manna G. Folic acid and homocysteine in chronic kidney disease and cardiovascular disease progression: which comes first? Cardiorenal Med. 2017;7(4):255–266. doi:10.1159/000471813
   PubMed Web of Science ®Google Scholar
• Branum AM, Bailey R, Singere BJ. Dietary supplement use and folate status during pregnancy in the United States. J Nutr. 2013;143(4):486–492. doi:10.3945/jn.112.169987
   PubMed Web of Science ®Google Scholar
• Wellings K, Jones KG, Mercer CH, et al. The prevalence of unplanned pregnancy and associated factors in Britain: findings from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). Lancet. 2013;382(9907):1807–1816. doi:10.1016/S0140-6736(13)62071-1
   PubMed Web of Science ®Google Scholar
• Yila TA, Araki A, Sasaki S, et al. Predictors of folate status among pregnant Japanese women: the Hokkaido Study on environment and children’s health, 2002–2012. Br J Nutr. 2016;115(12):2227–2235. doi:10.1017/S0007114516001628
   PubMed Web of Science ®Google Scholar
• Castano E, Caviedes L, Hirsch S, Llanos M, Iniguez G, Ronco AM. Folate transporters in placentas from preterm newborns and their relation to cord blood folate and vitamin B12 levels. PLoS One. 2017;12(1):e0170389. doi:10.1371/journal.pone.0170389
   PubMed Web of Science ®Google Scholar
• Caviedes L, Iniguez G, Hidalgo P, Castro JJ, Castano E, Llanos M. Relationship between folate transporters expression in human placentas at term and birth weights. Placenta. 2016;38:24–28. doi:10.1016/j.placenta.2015.12.007
   PubMed Web of Science ®Google Scholar
• Yasuda S, Hasui S, Yamamoto C, et al. Placental folate transport during pregnancy. Biosci Biotechnol Biochem. 2008;72(9):2277–2284. doi:10.1271/bbb.80112
   PubMed Web of Science ®Google Scholar
• Butler Walker J, Houseman J, Seddon L, et al. Maternal and umbilical cord blood levels of mercury, lead, cadmium, and essential trace elements in Arctic Canada. Environ Res. 2006;100(3):295–318. doi:10.1016/j.envres.2005.05.006
   PubMed Web of Science ®Google Scholar
• Kim YM, Chung JY, An HS, et al. Biomonitoring of lead, cadmium, total mercury, and methylmercury levels in maternal blood and in umbilical cord blood at birth in South Korea. Int J Environ Res Public Health. 2015;12(10):13482–13493. doi:10.3390/ijerph121013482
   PubMed Web of Science ®Google Scholar
• Chen MY, Rose CE, Qi YP, et al. Defining the plasma folate concentration associated with the red blood cell folate concentration threshold for optimal neural tube defects prevention: a population-based, randomized trial of folic acid supplementation. Am J Clin Nutr. 2019;109(5):1452–1461. doi:10.1093/ajcn/nqz027
   PubMed Web of Science ®Google Scholar
• Vashi P, Edwin P, Popiel B, Lammersfeld C, Gupta D, Sengupta S. Methylmalonic acid and homocysteine as indicators of vitamin B-12 deficiency in cancer. PLoS One. 2016;11(1):e0147843. doi:10.1371/journal.pone.0147843
   PubMed Web of Science ®Google Scholar