Association of Overweight and Inflammatory Indicators with Breast Cancer: A Cross-Sectional Study in Chinese Women

References

• Mattiuzzi C, Lippi G. Current Cancer Epidemiology. J Epidemiol Glob Health. 2019;9(4):217–222. doi:10.2991/jegh.k.191008.001
   PubMed Web of Science ®Google Scholar
• Harbeck N, Penault-Llorca F, Cortes J, et al. Breast cancer. Nature Reviews Disease Primers. 2019;5(1):66. doi:10.1038/s41572-019-0111-2
   PubMed Web of Science ®Google Scholar
• Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. Ca a Cancer J Clinicians. 2021;71(3):209–249. doi:10.3322/caac.21660
   PubMed Web of Science ®Google Scholar
• Xia C, Dong X, Li H, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants. Chin Med J (Engl). 2022;135(5):584–590. doi:10.1097/CM9.0000000000002108
   PubMed Web of Science ®Google Scholar
• Jubair S, Alkhateeb A, Tabl AA, Rueda L, Ngom A. A novel approach to identify subtype-specific network biomarkers of breast cancer survivability. Network Model Anal Health Inf Bioinf. 2020;9(1):43. doi:10.1007/s13721-020-00249-4
   Google Scholar
• Zhou L, Rueda M, Alkhateeb A. Classification of Breast Cancer Nottingham Prognostic Index Using High-Dimensional Embedding and Residual Neural Network. Cancer Epidemiol Biomarkers Prev. 2022;14(4):934.
   Google Scholar
• Pischon T, Nimptsch K. Obesity and Risk of Cancer: an Introductory Overview. Recent Results Cancer Res. 2016;208:1–15. doi:10.1007/978-3-319-42542-9_1
   PubMedGoogle Scholar
• Soltani G, Poursheikhani A, Yassi M, Hayatbakhsh A, Kerachian M, Kerachian MA. Obesity, diabetes and the risk of colorectal adenoma and cancer. BMC Endocr Disord. 2019;19(1):113. doi:10.1186/s12902-019-0444-6
   PubMed Web of Science ®Google Scholar
• Ko SH, Han KD, Yun JS, Chung S, Koh ES. Impact of obesity and diabetes on the incidence of kidney and bladder cancers: a nationwide cohort study. Eur J Endocrinol. 2019;181(5):489–498. doi:10.1530/EJE-19-0500
   PubMed Web of Science ®Google Scholar
• McDonald ME, Bender DP. Endometrial Cancer: obesity, Genetics, and Targeted Agents. Obstet Gynecol Clin North Am. 2019;46(1):89–105. doi:10.1016/j.ogc.2018.09.006
   PubMed Web of Science ®Google Scholar
• Uhlenhopp DJ, Then EO, Sunkara T, Gaduputi V. Epidemiology of esophageal cancer: update in global trends, etiology and risk factors. Clin J Gastroenterol. 2020. doi:10.1007/s12328-020-01237-x
   PubMed Web of Science ®Google Scholar
• Dai L, Song K, Di W. Adipocytes: active facilitators in epithelial ovarian cancer progression? J Ovarian Res. 2020;13(1):115. doi:10.1186/s13048-020-00718-4
   PubMedGoogle Scholar
• Avgerinos KI, Spyrou N, Mantzoros CS, Dalamaga M. Obesity and cancer risk: emerging biological mechanisms and perspectives. Metabolism. 2019;92:121–135. doi:10.1016/j.metabol.2018.11.001
   PubMed Web of Science ®Google Scholar
• Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K. Body Fatness and Cancer--Viewpoint of the IARC Working Group. New Engl J Med. 2016;375(8):794–798. doi:10.1056/NEJMsr1606602
   PubMed Web of Science ®Google Scholar
• Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. New Engl J Med. 2003;348(17):1625–1638. doi:10.1056/NEJMoa021423
   PubMed Web of Science ®Google Scholar
• Terlikowska KM, Dobrzycka B, Terlikowski R, Sienkiewicz A, Kinalski M, Terlikowski SJ. Clinical value of selected markers of angiogenesis, inflammation, insulin resistance and obesity in type 1 endometrial cancer. BMC Cancer. 2020;20(1):921. doi:10.1186/s12885-020-07415-x
   PubMed Web of Science ®Google Scholar
• Christopoulos PF, Msaouel P, Koutsilieris M. The role of the insulin-like growth factor-1 system in breast cancer. Mol Cancer. 2015;14(1):43. doi:10.1186/s12943-015-0291-7
   PubMedGoogle Scholar
• Kang C, LeRoith D, Gallagher EJ. Diabetes, Obesity, and Breast Cancer. Endocrinology. 2018;159(11):3801–3812. doi:10.1210/en.2018-00574
   PubMed Web of Science ®Google Scholar
• Becker MA, Ibrahim YH, Cui X, Lee AV, Yee D. The IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells. Mol Endocrinol. 2011;25(3):516–528. doi:10.1210/me.2010-0373
   PubMedGoogle Scholar
• Kolb R, Sutterwala FS, Zhang W. Obesity and cancer: inflammation bridges the two. Curr. Opin. Pharmacol. 2016;29:77–89. doi:10.1016/j.coph.2016.07.005
   PubMed Web of Science ®Google Scholar
• Zimta AA, Tigu AB, Muntean M, Cenariu D, Slaby O, Berindan-Neagoe I. Molecular Links between Central Obesity and Breast Cancer. Int J Mol Sci. 2019;20(21):56.
   Web of Science ®Google Scholar
• Agurs-Collins T, Ross SA, Dunn BK. The Many Faces of Obesity and Its Influence on Breast Cancer Risk. Front Oncol. 2019;9:765. doi:10.3389/fonc.2019.00765
   PubMedGoogle Scholar
• Christodoulatos GS, Antonakos G, Karampela I, et al. Circulating Omentin-1 as a Biomarker at the Intersection of Postmenopausal Breast Cancer Occurrence and Cardiometabolic Risk: an Observational Cross-Sectional Study. Biomolecules. 2021;11(11).
   PubMed Web of Science ®Google Scholar
• Pierobon M, Frankenfeld CL. Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis. Breast Cancer Res Treat. 2013;137(1):307–314. doi:10.1007/s10549-012-2339-3
   PubMed Web of Science ®Google Scholar
• Kamineni A, Anderson ML, White E, et al. Body mass index, tumor characteristics, and prognosis following diagnosis of early-stage breast cancer in a mammographically screened population. Cancer Causes Control. 2013;24(2):305–312. doi:10.1007/s10552-012-0115-7
   PubMed Web of Science ®Google Scholar
• Buono G, Crispo A, Giuliano M, et al. Combined effect of obesity and diabetes on early breast cancer outcome: a prospective observational study. Oncotarget. 2017;8(70):115709–115717. doi:10.18632/oncotarget.22977
   PubMedGoogle Scholar
• Ewertz M, Jensen MB, Gunnarsdottir KA, et al. Effect of obesity on prognosis after early-stage breast cancer. J Clin Oncol. 2011;29(1):25–31. doi:10.1200/JCO.2010.29.7614
   PubMed Web of Science ®Google Scholar
• Gajeton J, Krukovets I, Muppala S, Verbovetskiy D, Zhang J, Stenina-Adognravi O. Hyperglycemia-Induced miR-467 Drives Tumor Inflammation and Growth in Breast Cancer. Cancers. 2021;13(6):1346. doi:10.3390/cancers13061346
   PubMed Web of Science ®Google Scholar
• Wang JY, Cai YN, Yu FF, Ping ZG, Liu L. Body mass index increases the lymph node metastasis risk of breast cancer: a dose-response meta-analysis with 52904 subjects from 20 cohort studies. Bmc Cancer. 2020;20(1).
   Google Scholar
• Sun N, Ma D, Gao P, et al. Construction of a Prognostic Risk Prediction Model for Obesity Combined With Breast Cancer. Front Endocrinol (Lausanne). 2021;12:712513. doi:10.3389/fendo.2021.712513
   PubMed Web of Science ®Google Scholar
• Picon-Ruiz M, Morata-Tarifa C, Valle-Goffin JJ, Friedman ER, Slingerland JM. Obesity and adverse breast cancer risk and outcome: mechanistic insights and strategies for intervention. CA Cancer J Clin. 2017;67(5):378–397. doi:10.3322/caac.21405
   PubMed Web of Science ®Google Scholar
• Bandera EV, Chandran U, Zirpoli G, et al. Body size in early life and breast cancer risk in African American and European American women. Cancer Causes Control. 2013;24(12):2231–2243. doi:10.1007/s10552-013-0302-1
   PubMed Web of Science ®Google Scholar
• Gilbert CA, Slingerland JM. Cytokines, obesity, and cancer: new insights on mechanisms linking obesity to cancer risk and progression. Ann Rev Med. 2013;64:45–57. doi:10.1146/annurev-med-121211-091527
   PubMed Web of Science ®Google Scholar
• Picon-Ruiz M, Pan C, Drews-Elger K, et al. Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b-Mediated Malignant Progression. Cancer Res. 2016;76(2):491–504. doi:10.1158/0008-5472.Can-15-0927
   PubMed Web of Science ®Google Scholar
• Dirat B, Bochet L, Dabek M, et al. Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion. Cancer Res. 2011;71(7):2455–2465. doi:10.1158/0008-5472.Can-10-3323
   PubMed Web of Science ®Google Scholar
• Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420(6917):860–867. doi:10.1038/nature01322
   PubMed Web of Science ®Google Scholar
• Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature. 2008;454(7203):436–444. doi:10.1038/nature07205
   PubMed Web of Science ®Google Scholar
• Cabia B, Andrade S, Carreira MC, Casanueva FF, Crujeiras AB. A role for novel adipose tissue-secreted factors in obesity-related carcinogenesis. Obes Rev. 2016;17(4):361–376. doi:10.1111/obr.12377
   PubMed Web of Science ®Google Scholar
• Sahin-Efe A, Katsikeris F, Mantzoros CS. Advances in adipokines. Metabolism. 2012;61(12):1659–1665. doi:10.1016/j.metabol.2012.09.001
   PubMed Web of Science ®Google Scholar
• Chooi YC, Ding C, Magkos F. The epidemiology of obesity. Metabolism. 2019;92:6–10. doi:10.1016/j.metabol.2018.09.005
   PubMed Web of Science ®Google Scholar
• He W, Li Q, Yang M, et al. Lower BMI cutoffs to define overweight and obesity in China. Obesity. 2015;23(3):684–691. doi:10.1002/oby.20995
   PubMed Web of Science ®Google Scholar
• Danforth DN. The Role of Chronic Inflammation in the Development of Breast Cancer. Cancers. 2021;13(15):3918.
   PubMed Web of Science ®Google Scholar
• Chlebowski RT, Aragaki AK, Anderson GL, et al. Dietary Modification and Breast Cancer Mortality: long-Term Follow-Up of the Women’s Health Initiative Randomized Trial. J Clin Oncol. 2020;38(13):1419–1428. doi:10.1200/JCO.19.00435
   PubMed Web of Science ®Google Scholar
• Mackenzie H, Markar SR, Askari A, et al. Obesity surgery and risk of cancer. Br J Surg. 2018;105(12):1650–1657. doi:10.1002/bjs.10914
   PubMed Web of Science ®Google Scholar
• Teras LR, Patel AV, Wang M, et al. Sustained Weight Loss and Risk of Breast Cancer in Women 50 Years and Older: a Pooled Analysis of Prospective Data. J Natl Cancer Inst. 2020;112(9):929–937. doi:10.1093/jnci/djz226
   PubMedGoogle Scholar
• Xu B, Lv L, Chen X, et al. Temporal relationships between BMI and obesity-related predictors of cardiometabolic and breast cancer risk in a longitudinal cohort. Sci Rep. 2023;13(1):12361. doi:10.1038/s41598-023-39387-w
   PubMed Web of Science ®Google Scholar
• Zhao D, Wang X, Beeraka NM, et al. High Body Mass Index Was Associated With Human Epidermal Growth Factor Receptor 2-Positivity, Histological Grade and Disease Progression Differently by Age. World j Oncol. 2023;14(1):75–83. doi:10.14740/wjon1543
   PubMedGoogle Scholar
• Mei Z, Shi L, Wang B, et al. Prognostic role of pretreatment blood neutrophil-to-lymphocyte ratio in advanced cancer survivors: a systematic review and meta-analysis of 66 cohort studies. Cancer Treat Rev. 2017;58:1–13. doi:10.1016/j.ctrv.2017.05.005
   PubMed Web of Science ®Google Scholar
• Templeton AJ, McNamara MG, Šeruga B, et al. Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. J Natl Cancer Inst. 2014;106(6):dju124. doi:10.1093/jnci/dju124
   PubMedGoogle Scholar
• Cho U, Park HS, Im SY, et al. Prognostic value of systemic inflammatory markers and development of a nomogram in breast cancer. PLoS One. 2018;13(7):e0200936. doi:10.1371/journal.pone.0200936
   PubMed Web of Science ®Google Scholar
• Giese MA, Hind LE, Huttenlocher A. Neutrophil plasticity in the tumor microenvironment. Blood. 2019;133(20):2159–2167. doi:10.1182/blood-2018-11-844548
   PubMed Web of Science ®Google Scholar
• Feng F, Zheng G, Wang Q, et al. Low lymphocyte count and high monocyte count predicts poor prognosis of gastric cancer. BMC Gastroenterol. 2018;18(1):148. doi:10.1186/s12876-018-0877-9
   PubMed Web of Science ®Google Scholar
• Zhang J, Huang SH, Li H, et al. Preoperative lymphocyte count is a favorable prognostic factor of disease-free survival in non-small-cell lung cancer. Med Oncol. 2013;30(1):352. doi:10.1007/s12032-012-0352-3
   PubMed Web of Science ®Google Scholar
• Wang K, Diao F, Ye Z, et al. Prognostic value of systemic immune-inflammation index in patients with gastric cancer. Chin J Cancer. 2017;36(1):75. doi:10.1186/s40880-017-0243-2
   PubMedGoogle Scholar
• Zhu M, Ma Z, Zhang X, et al. C-reactive protein and cancer risk: a pan-cancer study of prospective cohort and Mendelian randomization analysis. BMC Med. 2022;20(1):301. doi:10.1186/s12916-022-02506-x
   PubMed Web of Science ®Google Scholar
• Frydenberg H, Thune I, Lofterød T, et al. Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival. Breast Cancer Res Treat. 2016;155(2):345–354. doi:10.1007/s10549-015-3671-1
   PubMed Web of Science ®Google Scholar
• Guo L, Liu S, Zhang S, et al. C-reactive protein and risk of breast cancer: a systematic review and meta-analysis. Sci Rep. 2015;5:10508. doi:10.1038/srep10508
   PubMed Web of Science ®Google Scholar
• Nelson SH, Brasky TM, Patterson RE, et al. The Association of the C-Reactive Protein Inflammatory Biomarker with Breast Cancer Incidence and Mortality in the Women’s Health Initiative. Cancer Epidemiol Biomarkers Prev. 2017;26(7):1100–1106. doi:10.1158/1055-9965.EPI-16-1005
   PubMed Web of Science ®Google Scholar