References
- CrociDOSalatinoMTumor immune escape mechanisms that operate during metastasisCurr Pharm Biotechnol201112111923193621470132
- MareelMConstantinoSEcosystems of invasion and metastasis in mammary morphogenesis and cancerInt J Dev Biol2011557–967168422161824
- MacDonaldNChronic inflammatory states: their relationship to cancer prognosis and symptomsJ R Coll Physicians Edinb201141324625321949925
- GermainRNTumor immunologyBenaceraffBUnanueERTextbook of ImmunologyBaltimore, MDWilliams & Wilkins1979196217
- BarrettAJSavaniBNDoes chemotherapy modify the immune surveillance of hematological malignancies?Leukemia2009231535818830260
- ShurinMRNaiditchHGutkinDWUmanskyVShurinGVChemoImmunoModulation: immune regulation by the antineoplastic chemotherapeutic agentsCurr Med Chem201219121792180322414087
- WensveenFMvan GisbergenKPElderingEThe fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytesImmunol Rev201224918410322889217
- VossMJEntschladenFTumor interactions with soluble factors and the nervous systemCell Commun Signal201082120822525
- ShiaoSLGanesanAPRugoHSCoussensLMImmune microenvironments in solid tumors: new targets for therapyGenes Dev201125242559257222190457
- MellmanICoukosGDranoffGCancer immunotherapy comes of ageNature2011480737848048922193102
- LeiboviciJItzhakiOHuszarMSinaiJThe tumor microenvironment: part 1Immunotherapy20113111367138422053887
- LeiboviciJItzhakiOHuszarMSinaiJTargeting the tumor microenvironment by immunotherapy: part 2Immunotherapy20113111385140822053888
- MartinFApetohLGhiringhelliFRole of myeloid-derived suppressor cells in tumor immunotherapyImmunotherapy201241435722150000
- HaoNBLüMHFanYHCaoYLZhangZRYangSMMacrophages in tumor microenvironments and the progression of tumorsClin Dev Immunol2012201294809822778768
- FridlenderZGSunJKimSPolarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TANCancer Cell200916318319419732719
- BianchiGBorgonovoGPistoiaVRaffaghelloLImmunosuppressive cells and tumour microenvironment: focus on mesenchymal stem cells and myeloid derived suppressor cellsHistol Histopathol201126794195121630223
- ByrneWLMillsKHLedererJAO’SullivanGCTargeting regulatory T cells in cancerCancer Res201171226915692022068034
- MunnDHBlocking IDO activity to enhance anti-tumor immunityFront Biosci (Elite Ed)2012473474522201909
- MarleauAMChenCSJoyceJATullisRHExosome removal as a therapeutic adjuvant in cancerJ Transl Med20121013422738135
- MaYConfortiRAymericLL. How to improve the immunogenicity of chemotherapy and radiotherapyCancer Metastasis Rev2011301718221298323
- RosentalBAppelMYYossefRHadadUBrusilovskyMPorgadorAThe effect of chemotherapy/radiotherapy on cancerous pattern recognition by NK cellsCurr Med Chem201219121780179122414084
- BaronzioGGramagliaAFiorentiniGHyperthermia and immunity. A brief overviewIn Vivo2006206A68969517203747
- ChangAERosenbergSAOverview of interleukin-2 as an immunotherapeutic agentSemin Surg Oncol1989563853902688029
- RosenbergSAThe development of new immunotherapies for the treatment of cancer using interleukin-2. A reviewAnn Surg198820821211353041925
- TsungKNortonJALessons from Coley’s ToxinSurg Oncol2006151252816814541
- WiemannBStarnesCOColey’s toxins, tumor necrosis factor and cancer research: a historical perspectivePharmacol Ther19946435295647724661
- Rakoff-NahoumSMedzhitovRToll-like receptors and cancerNat Rev Cancer200991576319052556
- LawsonKAMorrisDGOncolytic virotherapy for renal cell carcinoma: a novel treatment paradigm?Expert Opin Biol Ther201212789190322564154
- PatyarSJoshiRByravDSPrakashAMedhiBDasBKBacteria in cancer therapy: a novel experimental strategyJ Biomed Sci20101712120331869
- RestifoNPDudleyMERosenbergSAAdoptive immunotherapy for cancer: harnessing the T cell responseNat Rev Immunol201212426928122437939
- KiesslingRKleinEWigzellH“Natural” killer cells in the mouse. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotypeEur J Immunol1975521121171234049
- CaligiuriMAHuman natural killer cellsBlood2008112346146918650461
- BironCAvan den ElsenPTuttMMMedveczkyPKumarVTerhorstCMurine natural killer cells stimulated in vivo do not express the T cell receptor alpha, beta, gamma, T3 delta, or T3 epsilon genesJ Immunol19871395170417103497976
- RobertsonMJRitzJBiology and clinical relevance of human natural killer cellsBlood19907612242124382265240
- KärreKLjunggrenHGPiontekGKiesslingRSelective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategyNature198631960556756783951539
- LanierLLNatural killer cells: from no receptors to too manyImmunity1997643713789133416
- LanierLLMissing self, NK cells, and the white albumJ Immunol200517411656515905491
- GrimmEAMazumderAZhangHZRosenbergSALymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin-2 activated autologous human peripheral blood lymphocytesJ Exp Med19821556182318416176669
- RosenbergSALotzeMTYangJCProspective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancerJ Natl Cancer Inst19938586226328468720
- KammulaUSMarincolaFMCancer immunotherapy: is there real progress at last?BioDrugs199911424926018031135
- RosenbergSAImmunotherapy of patients with advanced cancer using interleukin-2 alone or in combination with lymphokine activated killer cellsImportant Adv Oncol19882172573042605
- KimuraHYamaguchiYAA phase III randomized study of interleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinomaCancer199780142499210707
- SangioloDCytokine induced killer cells as promising immunotherapy for solid tumorsJ Cancer2011236336821716717
- WengDSZhouJZhouQMMinimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomasJ Immunother2008311637118157013
- WuCJiangJShiLXuNProspective study of chemotherapy in combination with cytokine-induced killer cells in patients suffering from advanced non-small cell lung cancerAnticancer Res2008286B3997400219192663
- ShiLZhouQWuJEfficacy of adjuvant immunotherapy with cytokine-induced killer cells in patients with locally advanced gastric cancerCancer Immunol Immunother201261122251225922674056
- ShubinaIZhBliumenbergAGVolkovSMDemidovLVKiselevskiĭMVAdoptive immunotherapy of malignanciesVestn Ross Akad Med Nauk200711915 Russian18080522
- MorganRADudleyMEWunderlichJRCancer regression in patients after transfer of genetically engineered lymphocytesScience2006314579612612916946036
- DoniaMEllebaekEAndersenMHStratenPSvaneIMAnalysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytesOncoimmunol20121812971304
- ShiHLiuLWangZImproving the efficacy and safety of engineered T cell therapy for cancerCancer Lett2013328219119723022475
- KellerRDendritic cells:their significance in health and diseaseImmunol Lett20017811312211578684
- SallustoFNicoloCDe MariaRCorintiSTestiRCeramide inhibits antigen uptake and presentation by dendritic cellsJ Exp Med19961846241124168976196
- HsuFJBenikeCFagnoniFVaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cellsNat Med19962152588564842
- NestleFOAlijagicSGillietMVaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cellsNat Med1998433283329500607
- RosenbergSAYangJCRestifoNPCancer immunotherapy: moving beyond current vaccinesNat Med200410990991515340416
- OshitaCTakikawaMKumeADendritic cell-based vaccination in metastatic melanoma patients: phase II clinical trialOncol Rep20122841131113822895835
- EggermontAMTherapeutic vaccines in solid tumours: can they be harmful?Eur J Cancer200945122087209019477117
- ChrvalaCAThe changing landscape of treatment options for metastatic castrate-resistant prostate cancer: challenges and solutions for physicians and patientsP T201237845346323091338
- PloskerGLSipuleucel-T: in metastatic castration-resistant prostate cancerDrugs201171110110821175243
- Di LorenzoGFerroMBuonerbaCSipuleucel-T (Provenge®) for castration-resistant prostate cancerBJU Int20121102 Pt 2E99E10422177289
- CathelinDNicolasABouchotAFraszczakJLabbéJBonnotteBDendritic cell-tumor cell hybrids and immunotherapy: what’s next?Cytotherapy201113777478521299362
- LiHWangCYuJDendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgeryCytotherapy20091181076108319929470
- WestEJScottKJJenningsVAMelcherAAImmune activation by combination human lymphokine-activated killer and dendritic cell therapyBr J Cancer2011105678779521847125
- AllenMLouise JonesJJekyll and Hyde: the role of the microenvironment on the progression of cancerJ Pathol2011223216217621125673
- KhatamiMUnresolved inflammation: ‘immune tsunami’ or erosion of integrity in immune-privileged and immune-responsive tissues and acute and chronic inflammatory diseases or cancerExpert Opin Biol Ther201111111419143221663532
- Ben-BaruchAInflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines and additional mediatorsSemin Cancer Biol2006161385216139507
- KalinskiPRegulation of immune responses by prostaglandin E2J Immunol20121881212822187483
- Le BitouxMAStamenkovicITumor-host interactions: the role of inflammationHistochem Cell Biol200813061079109018953558
- HariziHGualdeNPivotal role of PGE2 and IL-10 in the cross-regulation of dendritic cell-derived inflammatory mediatorsCell Mol Immunol20063427127716978535
- SevkoAUmanskyVMyeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thievesJ Cancer20134131123386900
- KaravitisJHixLMShiYHSchultzRFKhazaieKZhangMRegulation of COX2 expression in mouse mammary tumor cells controls bone metastasis and PGE2-induction of regulatory T cell migrationPLoS One201279e4634223029485
- SharmaSYangSCZhuLTumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancerCancer Res200565125211522015958566
- ObermajerNMuthuswamyRLesnockJEdwardsRPKalinskiPPositive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cellsBlood2011118205498550521972293
- VeltmanJDLambersMEvan NimwegenMCOX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC functionBMC Cancer20101046420804550
- DesserLHolomanovaDZavadovaEPavelkaKMohrTHerbacekIOral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human bloodCancer Chemother Pharmacol200147SupplS10S1511561866
- SrivastavaMKAnderssonÅZhuLMyeloid suppressor cells and immune modulation in lung cancerImmunotherapy20124329130422401635
- PastułaAMarcinkiewiczJMyeloid-derived suppressor cells: a double-edged sword?Int J Exp Pathol2011922737821314739
- NagarajSGabrilovichDIMyeloid-derived suppressor cells in human cancerCancer J201016434835320693846
- GretenTFMannsMPKorangyFMyeloid derived suppressor cells in human diseasesInt Immunopharmacol201111780280721237299
- ChalminFMignotGGhiringhelliFMyeloid-derived suppressor cells: a key player in cancerMed Sci (Paris)2010266–757657920619155
- FilipazziPHuberVRivoltiniLPhenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patientsCancer Immunol Immunother201261225526322120756
- KaoJKoECEisensteinSTargeting immune suppressing myeloid-derived suppressor cells in oncologyCrit Rev Oncol Hematol2011771121920304669
- NaiditchHShurinMRShurinGVTargeting myeloid regulatory cells in cancer by chemotherapeutic agentsImmunol Res2011502–327628521717082
- DjeuJWeiSChemoimmunomodulation of MDSCs as a novel strategy for cancer therapyOncoimmunology20121112112222720231
- GhiringhelliFRebeCHichamiADelmasDImmunomodulation and anti-inflammatory roles of polyphenols as anticancer agentsAnticancer Agents Med Chem201212885287322292769
- KoJSZeaAHRiniBISunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patientsClin Cancer Res20091562148215719276286
- TonguMHarashimaNMonmaHMetronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivoCancer Immunol Immunother201362238339122926062
- LathersDMClarkJIAchilleNJYoungMRPhase IB study of 25-hydroxyvitamin D(3) treatment to diminish suppressor cells in head and neck cancer patientsHum Immunol200162111282129311704292
- MirzaNFishmanMFrickeIAll-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patientsCancer Res200666189299930716982775
- ApetohLVégranFLadoireSGhiringhelliFRestoration of antitumor immunity through selective inhibition of myeloid derived suppressor cells by anticancer therapiesCurr Mol Med201111536537221568934
- van CruijsenHHoekmanKStamAGDefective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptorClin Dev Immunol200720071731518320010
- UgelSDelpozzoFDesantisGTherapeutic targeting of myeloid-derived suppressor cellsCurr Opin Pharmacol20099447048119616475
- FacciabeneAMotzGTCoukosGT-regulatory cells: key players in tumor immune escape and angiogenesisCancer Res20127292162217122549946
- WilkeCMWuKZhaoEWangGZouWPrognostic significance of regulatory T cells in tumorInt J Cancer2010127474875820473951
- ZouWRegulatory T cells, tumour immunity and immunotherapyNat Rev Immunol20066429530716557261
- GhiringhelliFMenardCPuigPEMetronomic cyclophosphamide regimen electively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patientsCancer Immunol Immunother200756564164816960692
- CoolsNPonsaertsPVan TendelooVFBernemanZNRegulatory T cells and human diseaseClin Dev Immunol200720078919518317534
- MuranskiPBoniAWrzesinskiCIncreased intensity lymphodepletion and adoptive immunotherapy – how far can we go?Nat Clin Pract Oncol200631266868117139318
- GrazianiGTentoriLNavarraPIpilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancerPharmacol Res201265192221930211
- PereHTanchotCBayryJComprehensive analysis of current approaches to inhibit regulatory T cells in cancerOncoimmunology20121332633322737608
- YaqubSHenjumKMahicMRegulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent mannerCancer Immunol Immunother200857681382117962941
- MandapathilMSzczepanskiMJSzajnikMAdenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cellsJ Biol Chem201028536275712758020558731
- DienstmannRMarkmanBTaberneroJApplication of monoclonal antibodies as cancer therapy in solid tumorsCurr Clin Pharmacol20127213714522432839
- LipsonEJDrakeCGIpilimumab: an anti-CTLA-4 antibody for metastatic melanomaClin Cancer Res201117226958696221900389
- SinghNMadanRAGulleyJLIpilimumab in prostate cancerExpert Opin Biol Ther201313230331323265575
- HodiFSO’DaySJMcDermottDFImproved survival with ipilimumab in patients with metastatic melanomaN Engl J Med2010363871172320525992
- RobertCThomasLBondarenkoIIpilimumab plus dacarbazine for previously untreated metastatic melanomaN Engl J Med2011364262517252621639810
- MargolinKIpilimumab in a Phase II trial of melanoma patients with brain metastasesOncoimmunology2012171197119923170278
- KhattakMAFisherRHughesPGoreMLarkinJIpilimumab activity in advanced uveal melanomaMelanoma Res2013231798123211837
- GerritsenWRThe evolving role of immunotherapy in prostate cancerAnn Oncol201223Suppl 8viii22viii2722918924
- ReckMBondarenkoILuftAIpilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trialAnn Oncol2013241758322858559
- FellnerCIpilimumab (Yervoy) Ipilimumab (yervoy) prolongs survival in advanced melanoma: serious side effects and a hefty price tag may limit its useP T201237950351123066344
- BakacsTMehrishiJNMossRWIpilimumab (Yervoy) and the TGN1412 catastropheImmunobiology2012217658358921821307
- ThurberGMSchmidtMMWittrupKDFactors determining antibody distribution in tumorsTrends Pharmacol Sci2008292576118179828
- ReubenJMLeeBNLiCBiologic and immunomodulatory events after CTLA-4 blockade with ticilimumab in patients with advanced malignant melanomaCancer2006106112437244416615096
- TopalianSLDrakeCGPardollDMTargeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunityCurr Opin Immunol201224220721222236695
- OkazakiTHonjoTPD-1 and PD-1 ligands: from discovery to clinical applicationInt Immunol200719781382417606980
- ZitvogelLKroemerGTargeting PD-1/PD-L1 interactions for cancer immunotherapyOncoimmunology2012181223122523243584
- Ménétrier-CauxCCurielTFagetJManuelMCauxCZouWTargeting regulatory T cellsTarget Oncol201271152822327882
- TopalianSLHodiFSBrahmerJRSafety, activity, and immune correlates of anti-PD-1 antibody in cancerN Engl J Med2012366262443245422658127
- TangPAHengDYProgrammed Death 1 Pathway inhibition in Metastatic Renal Cell Cancer and Prostate CancerCurr Oncol Rep20131529810423263823
- CurranMAMontalvoWYagitaHAllisonJPPD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumorsProc Natl Acad Sci USA201010794275428020160101
- ZhangHGGrizzleWEExosomes and cancer: a newly described pathway of immune suppressionClin Cancer Res201117595996421224375
- CamussiGDeregibusMCBrunoSGrangeCFonsatoVTettaCExosome/microvesicle-mediated epigenetic reprogramming of cellsAm J Cancer Res2011119811021969178
- IeroMValentiRHuberVTumour-released exosomes and their implications in cancer immunityCell Death Differ2008151808817932500
- LentzMRContinuous whole blood UltraPheresis procedure in patients with metastatic cancerJ Biol Response Mod1989855115272795094