References
- BedoretDWallemacqHMarichalTLung interstitial macrophages alter dendritic cell functions to prevent airway allergy in miceJ Clin Invest2009119123723373819907079
- BoorsmaCEDraijerCMelgertBNMacrophage heterogeneity in respiratory diseasesMediators Inflamm2013201376921423533311
- JiWJMaYQZhouXTemporal and spatial characterization of mononuclear phagocytes in circulating, lung alveolar and interstitial compartments in a mouse model of bleomycin-induced pulmonary injuryJ Immunol Methods20144031–271624280595
- MurrayPJAllenJEBiswasSKMacrophage activation and polarization: nomenclature and experimental guidelinesImmunity2014411142025035950
- VeremeykoTSiddiquiSSotnikovIYungAPonomarevEDIL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammationPLoS One2013812e8177424358127
- BaiJAdrianiGDangTMContact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactionsOncotarget2015628252952530726231039
- ColinSChinetti-GbaguidiGStaelsBMacrophage phenotypes in atherosclerosisImmunol Rev2014262115316625319333
- JuddLMHeineRGMenheniottTRElevated IL-33 expression is associated with pediatric eosinophilic esophagitis, and exogenous IL-33 promotes eosinophilic esophagitis development in miceAm J Physiol Gastrointest Liver Physiol20163101G13G2526514775
- DraijerCBoorsmaCEReker-SmitCPostEPoelstraKMelgertBNPGE2-treated macrophages inhibit development of allergic lung inflammation in miceJ Leukoc Biol Epub201631
- MoreiraAPHogaboamCMMacrophages in allergic asthma: fine-tuning their pro- and anti-inflammatory actions for disease resolutionJ Interferon Cytokine Res201131648549121631355
- ZdrengheaMTMakriniotiHMuresanAJohnstonSLStanciuLAThe role of macrophage IL-10/innate IFN interplay during virus-induced asthmaRev Med Virol2015251334925430775
- StaplesKJHinksTSWardJAGunnVSmithCDjukanovicRPhenotypic characterization of lung macrophages in asthmatic patients: overexpression of CCl17J Allergy Clin Immunol20121301404–1412e1407
- ChungYHongJYLeiJChenQBentleyJKHershensonMBRhinovirus infection induces interleukin-13 production from CD11b-positive, M2-polarized exudative macrophagesAm J Respir Cell Mol Biol201552220521625029349
- LambrechtBNHammadHThe immunology of asthmaNat Immunol2015161455625521684
- PerdigueroEGGeissmannFThe development and maintenance of resident macrophagesNat Immunol20151712826681456
- SuzukiTArumugamPSakagamiTPulmonary macrophage transplantation therapyNature201451445045425274301
- AmitIWinterDRJungSThe role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasisNat Immunol2015171182526681458
- BeckerMDe BastianiMAParisiMMIntegrated transcriptomics establish macrophage polarization signatures and have potential applications for clinical health and diseaseSci Rep201551335126302899
- GlassCKNatoliGMolecular control of activation and priming in macrophagesNat Immunol2015171263326681459
- RosasMDaviesLCGilesPJThe transcription factor Gata6 links tissue macrophage phenotype and proliferative renewalScience2014344618464564824762537
- SoucieELWengZGeirsdottirLLineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cellsScience20163516274aad551026797145
- MathieSADixonKLWalkerSAAlveolar macrophages are sentinels of murine pulmonary homeostasis following inhaled antigen challengeAllergy2015701808925331546
- Lauzon-JosetJFMarsolaisDLangloisABissonnetteEYDysregulation of alveolar macrophages unleashes dendritic cell-mediated mechanisms of allergic airway inflammationMucosal Immunol20147115516423715174
- LeeYGJeongJJNyenhuisSRecruited alveolar macrophages, in response to airway epithelial-derived monocyte chemoattractant protein 1/CCl2, regulate airway inflammation and remodeling in allergic asthmaAm J Respir Cell Mol Biol201552677278425360868
- ZaslonaZPrzybranowskiSWilkeCResident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthmaJ Immunol201419384245425325225663
- WinklerCWitteLMorawNImpact of endobronchial allergen provocation on macrophage phenotype in asthmaticsBMC Immunol2014151224612750
- RupilLLde BemAFRothGADiphenyl diselenide-modulation of macrophage activation: down-regulation of classical and alternative activation markersInnate Immun201218462763722215443
- RobbePDraijerCBorgTRDistinct macrophage phenotypes in allergic and nonallergic lung inflammationAm J Physiol Lung Cell Mol Physiol20153084L358L36725502502
- DraijerCRobbePBoorsmaCEHylkemaMNMelgertBNCharacterization of macrophage phenotypes in three murine models of house-dust-mite-induced asthmaMediators Inflamm2013201363204923533309
- TariqueAALoganJThomasEHoltPGSlyPDFantinoEPhenotypic, functional, and plasticity features of classical and alternatively activated human macrophagesAm J Respir Cell Mol Biol201553567668825870903
- VerreckFAde BoerTLangenbergDMHuman IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteriaProc Natl Acad Sci U S A2004101134560456515070757
- Sierra-FilardiEVegaMASanchez-MateosPCorbiALPuig-KrogerAHeme oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 releaseImmunobiology20102159–1078879520580464
- AroraSHernandezYErb-DownwardJRMcDonaldRAToewsGBHuffnagleGBRole of IFN-γ in regulating T2 immunity and the development of alternatively activated macrophages during allergic bronchopulmonary mycosisJ Immunol2005174106346635615879135
- van TitsLJStienstraRvan LentPLNeteaMGJoostenLAStalenhoefAFOxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Kruppel-like factor 2Atherosclerosis2011214234534921167486
- TianSZhangLTangJGuoXDongKChenSYHMGB1 exacerbates renal tubulointerstitial fibrosis through facilitating M1 macrophage phenotype at the early stage of obstructive injuryAm J Physiol Renal Physiol20153081F69F7525377911
- ShivshankarPHaladeGVCalhounCCaveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarctionJ Mol Cell Cardiol201476849325128086
- NomuraMLiuJRoviraIIFatty acid oxidation in macrophage polarizationNat Immunol201617321621726882249
- VenosaAMalaviyaRChoiHGowAJLaskinJDLaskinDLCharacterization of distinct macrophage subpopulations during nitrogen mustard-induced lung injury and fibrosisAm J Respir Cell Mol Biol201654343644626273949
- HongJYChungYSteenrodJMacrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthmaRespir Res2014156324907978
- ZhongBYangXSunQPdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammationJ Leukoc Biol20149661065107525097194
- BhatiaSFeiMYarlagaddaMRapid host defense against Aspergillus fumigatus involves alveolar macrophages with a predominance of alternatively activated phenotypePLoS One201161e1594321246055
- ChangHYLeeHNKimWSurhYJDocosahexaenoic acid induces M2 macrophage polarization through peroxisome proliferator-activated receptor gamma activationLife Sci2015120394725445227
- GageEHernandezMOO’HaraJMMcCarthyEAMantisNJRole of the mannose receptor (CD206) in innate immunity to ricin toxinToxins2011391131114522069759
- LuJCaoQZhengDDiscrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney diseaseKidney Int201384474575523636175
- JiangZRavaioliGFehrenbachMLLipoprotein associated phospholipase A2 (LP-PLA2)/platelet activating factor acetyl hydrolase (PAF-AH) deficiency is associated with increased numbers of M2 macrophages in the lung during the allergic airway response in miceAm J Respir Crit Care Med2012185A4302
- JiangZKokalariBRedaiIGHanmanNMacpheeCHHaczkuALack of lipoprotein associated phospholipase A2 (Lp-PLA2) enhanced phagocytosis and IL-10 expression and decreased NF-kB activation in CD206+ M2 macrophages in gene deficient miceAm J Respir Crit Care Med2014189A2485
- JiangZKokalariBRedaiIGLack of surfactant protein A (SP-A) enhances airway inflammation and hyperresponsiveness after ozone (O3) or Aspergillus fumigatus (Af) exposure in association with increased presence of IL-13+/CD206+ alternatively activated (M2) macrophagesAm J Respir Crit Care Med2013187A3554
- BuechlerCRitterMOrsoELangmannTKluckenJSchmitzGRegulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuliJ Leukoc Biol20006719710310648003
- ByersDEHoltzmanMJAlternatively activated macrophages and airway diseaseChest2011140376877421896520
- SiddiquiSSecorERJrSilbartLKBroncho-alveolar macrophages express chemokines associated with leukocyte migration in a mouse model of asthmaCell Immunol2013281215916923685352
- MalaviaNKMihJDRaubCBDinhBTGeorgeSCIL-13 induces a bronchial epithelial phenotype that is profibroticRespir Res200892718348727
- DongLWangSJCamoretti-MercadoBLiHJChenMBiWXFIZZ1 plays a crucial role in early stage airway remodeling of OVA-induced asthmaJ Asthma200845864865318951255
- NairMGCochraneDWAllenJEMacrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitroImmunol Lett200385217318012527225
- BleaseKMehradBStandifordTJEnhanced pulmonary allergic responses to Aspergillus in CCR2-/- miceJ Immunol200016552603261110946288
- MullerUStenzelWKohlerGIL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformansJ Immunol200717985367537717911623
- NabeTWakamoriHYanoCProduction of interleukin (IL)-33 in the lungs during multiple antigen challenge-induced airway inflammation in mice, and its modulation by a glucocorticoidEur J Pharmacol2015757344125797285
- JoshiADOakSRHartiganAJInterleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophagesBMC Immunol2010115220958987
- Kurowska-StolarskaMStolarskiBKewinPIL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammationJ Immunol2009183106469647719841166
- WongCKLeungTFChuIMDongJLamYYLamCWAberrant expression of regulatory cytokine IL-35 and pattern recognition receptor NOD2 in patients with allergic asthmaInflammation201538134836025326182
- ZhuLYangTLiLTSC1 controls macrophage polarization to prevent inflammatory diseaseNat Commun20145469625175012
- YoshidaKMaekawaTZhuYThe transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memoryNat Immunol201516101034104326322480
- WeiQShaYBhattacharyaARegulation of IL-4 receptor signaling by STUB1 in lung inflammationAm J Respir Crit Care Med20141891162924251647
- ZhangQZhaoKShenQTet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6Nature2015525756938939326287468
- Karo-AtarDItanMPasmanik-ChorMMunitzAMicroRNA profiling reveals opposing expression patterns for miR-511 in alternatively and classically activated macrophagesJ Asthma201552654555325405361
- Baroja-MazoAMartin-SanchezFGomezAIThe NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory responseNat Immunol201415873874824952504
- BruchardMRebeCDerangereVThe receptor NLRP3 is a transcriptional regulator of TH2 differentiationNat Immunol201516885987026098997
- Vande WalleLVan OpdenboschNJacquesPNegative regulation of the NLRP3 inflammasome by A20 protects against arthritisNature20145127512697325043000
- SatohTTakeuchiOVandenbonAThe Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infectionNat Immunol2010111093694420729857
- LiuGMaHQiuLPhenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in miceImmunol Cell Biol201189113014220514074
- TiemessenMMJaggerALEvansHGvan HerwijnenMJJohnSTaamsLSCD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophagesProc Natl Acad Sci U S A200710449194461945118042719
- SongXXieSLuKWangCMesenchymal stem cells alleviate experimental asthma by inducing polarization of alveolar macrophagesInflammation201538248549224958014
- BrazaFDirouSForestVMesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthmaStem Cells Epub2016217
- YinXPangCBaiLZhangYGengLAdipose-derived stem cells promote the polarization from M1 macrophages to M2 macrophagesXi Bao Yu Fen Zi Mian Yi Xue Za Zhi/Chin J Cell Mol Immunol2016323332338 Chinese
- AbomarayFMAl JumahMAKalionisBHuman chorionic villous mesenchymal stem cells modify the functions of human dendritic cells, and induce an anti-inflammatory phenotype in CD1+ dendritic cellsStem Cell Rev201511342344125287760
- FrancoisMRomieu-MourezRLiMGalipeauJHuman MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiationMol Ther201220118719521934657