Al-hijamah and oral honey for treating thalassemia, conditions of iron overload, and hyperferremia: toward improving the therapeutic outcomes

References

• El SayedSMMahmoudHSNaboMMHMedical and scientific bases of wet cupping therapy (Al-hijamah): in light of modern medicine and prophetic medicineAltern Integ Med201323116
   Google Scholar
• AlshowafiFKEffect of blood cupping on some biochemical parameterMed J Cairo Univ201078311315
   Google Scholar
• AhmedSMMadboulyNHMakladSSAbu-ShadyEAImmunomodulatory effects of blood letting cupping therapy in patients with rheumatoid arthritisEgypt J Immunol2005122395117977209
   PubMedGoogle Scholar
• YunGWYangYJSongICA prospective evaluation of adult men with iron-deficiency anemia in KoreaIntern Med201150131371137521720055
   PubMed Web of Science ®Google Scholar
• ZhangCQLiangTJZhangWEffects of drug cupping therapy on immune function in chronic asthmatic bronchitis patients during protracted periodZhongguo Zhong Xi Yi Jie He Za Zhi20062611984987 Chinese17186726
   PubMedGoogle Scholar
• Cals-GriersonMMOrmerodADNitric oxide function in the skinNitric Oxide200410417919315275864
   PubMed Web of Science ®Google Scholar
• BoisselJPOhlyDBrosMGödtel-ArmbrustUFörstermannUFrankSThe neuronal nitric oxide synthase is upregulated in mouse skin repair and in response to epidermal growth factor in human HaCaT keratinocytesJ Invest Dermatol2004123113213915191553
   PubMed Web of Science ®Google Scholar
• RendellMSJohnsonMLSmithDSkin blood flow response in the rat model of wound healing: expression of vasoactive factorsJ Surg Res20021071182612384060
   PubMed Web of Science ®Google Scholar
• LeeRHEfronDTantryUBarbulANitric oxide in the healing wound: a time-course studyJ Surg Res2001101110410811676563
   PubMed Web of Science ®Google Scholar
• WinkDAMirandaKMEspeyMGMechanisms of the antioxidant effects of nitric oxideAntioxid Redox Signal2001320321311396476
   PubMed Web of Science ®Google Scholar
• El SayedSMAl-qulitiAMahmoudHSTherapeutic benefits of Al-hijamah: in light of modern medicine and prophetic medicineAJMBR224671
   Google Scholar
• KanitakisJAnatomy, histology and immunohistochemistry of normal human skinEur J Dermatol20021239039912095893
   PubMed Web of Science ®Google Scholar
• El SayedSMAbou-TalebAMahmoudHSPercutaneous excretion of iron and ferritin (through Al-hijamah) as a novel treatment for iron overload in beta-thalassemia major, hemochromatosis and sideroblastic anemiaMed Hypotheses201483223824624857772
   PubMed Web of Science ®Google Scholar
• SaladinKSThe circulatory system: blood vessels and circulationAnatomy and Physiology: The Unity of Form and Function3rd edNew YorkMcGraw-Hill2003756781
   Google Scholar
• BouwstraJAHoneywell-NguyenPLGoorisGSPonecMStructure of the skin barrier and its modulation by vesicular formulationsProg Lipid Res200342113612467638
   PubMed Web of Science ®Google Scholar
• YoungBHeathJWSkinWheater’s Functional Histology: A Text and Colour Atlas4th edLondonChurchill Livingstone2000164
   Google Scholar
• HuberREmerichMBraeunigMCupping – is it reproducible? Experiments about factors determining the vacuumComplement Ther Med2011192788321549258
   PubMed Web of Science ®Google Scholar
• El SayedSMMahmoudHSNaboMMHMethods of Wet Cupping Therapy (Al-hijamah): In Light of Modern Medicine and Prophetic MedicineAltern Integ Med20132116
   Google Scholar
• MichalsenABockSLüdtkeREffects of traditional cupping therapy in patients with carpal tunnel syndrome: a randomized controlled trialJ Pain200910660160819380259
   PubMed Web of Science ®Google Scholar
• KimJIKimTHLeeMSEvaluation of wet-cupping therapy for persistent non-specific low back pain: a randomised, waiting-list controlled, open-label, parallel-group pilot trialTrials20111214621663617
   PubMed Web of Science ®Google Scholar
• XuJLinRWangJEffect of acupuncture anesthesia on acne vulgaris of pricking-bloodletting cupping: a single-blind randomized clinical trailJ Tradit Chin Med201333675275624660606
   PubMed Web of Science ®Google Scholar
• ZhangSJLiuJPHeKQTreatment of acute gouty arthritis by blood-letting cupping plus herbal medicineJ Tradit Chin Med2010301182020397456
   PubMed Web of Science ®Google Scholar
• ErqingDHaiyingLZhankaoZOne hundred and eighty-nine cases of acute articular soft tissue injury treated by blood-letting puncture with plum-blossom needle and cuppingJ Tradit Chin Med200525210410516136937
   PubMedGoogle Scholar
• PanHThirty-two cases of acne treated with blood-letting puncture, cupping and Chinese-drug facemaskJ Tradit Chin Med200525427027216447668
   PubMedGoogle Scholar
• HuangYLCupping-bloodletting therapy of Saudi Arabia and its clinical applicationZhongguo Zhen Jiu2008285375377 Chinese18652333
   PubMedGoogle Scholar
• AhmadiASchwebelDCRezaeiMThe efficacy of wet-cupping in the treatment of tension and migraine headacheAm J Chin Med2008361374418306448
   PubMed Web of Science ®Google Scholar
• HekmatpouHMoeiniLHaji-NadaliSThe effectiveness of wet cupping vs venesection on arterial O2 saturation level of cigarette smokers: A randomized controlled clinical trialPak J Med Sci20132961349135324550951
   PubMed Web of Science ®Google Scholar
• MahmoudHSAbou-El-NagaMOmarNAAEl-GhazzawyHAFathyYMNaboMMHAnatomical sites for practicing Wet Cupping Therapy (Al-Hijamah): In Light of Modern Medicine and Prophetic MedicineAltern Integ Med201328130
   Google Scholar
• WengYMHsiaoCTAcquired hemophilia A associated with therapeutic cuppingAm J Emerg Med2008268970. e1970. e218926376
   PubMedGoogle Scholar
• BluntSBLeeHPCan traditional “cupping” treatment cause a stroke?Med Hypotheses201074594594920031334
   PubMed Web of Science ®Google Scholar
• MoonSHHanHHRhieJWFactitious panniculitis induced by cupping therapyJ Craniofac Surg20112262412241422134296
   PubMed Web of Science ®Google Scholar
• KimKHKimTHHwangboMYangGYAnaemia and skin pigmentation after excessive cupping therapy by an unqualified therapist in Korea: a case reportAcupunct Med201230322722822738805
   PubMed Web of Science ®Google Scholar
• LeeHJParkNHYunHJKimSJoDYCupping therapy-induced iron deficiency anemia in a healthy manAm J Med20081218e5e618691469
   PubMed Web of Science ®Google Scholar
• GradyRWGalanelloRRandolphREKleinertDADessiCGiardinaPJToward optimizing the use of deferasirox: potential benefits of combined use with deferoxamineHaematologica201398112913522875626
   PubMed Web of Science ®Google Scholar
• AngelucciEMurettoPLucarelliGPhlebotomy to reduce iron overload in patients cured of thalassemia by bone marrow transplantation. Italian Cooperative Group for Phlebotomy Treatment of Transplanted Thalassemia PatientsBlood19979039949989242528
   PubMed Web of Science ®Google Scholar
• ShinarERachmilewitzEALuxSEDiffering erythrocyte membrane skeletal protein defects in alpha and beta thalassemiaJ Clin Invest19898324044102521488
   PubMed Web of Science ®Google Scholar
• GaliliUKorkeshAKahaneIRachmilewitzEADemonstration of a natural antigalactosyl IgG antibody on thalassemic red blood cellsBlood1983616125812646839023
   PubMed Web of Science ®Google Scholar
• Raha-ChowdhuryRWilliamsBJWorwoodMRed cell destruction by human monocytes – changes in intracellular ferritin concentration and phenotypeEur J Haematol199350126318436211
   PubMed Web of Science ®Google Scholar
• AnthiAOrfanosSEArmaganidisAPulmonary hypertension in β thalassaemiaLancet Respir Med20131648849624429247
   PubMed Web of Science ®Google Scholar
• AraujoJARomanoELBritoBEIron overload augments the development of atherosclerotic lesions in rabbitsArterioscler Thromb Vasc Biol1995158117211807542998
   PubMed Web of Science ®Google Scholar
• CardierJRomanoESoyanoAEffect of hepatic isoferritins from iron overloaded rats on lymphocyte proliferative response: role of ferritin iron contentImmunopharmacol Immunotoxicol19951747197328537608
   PubMed Web of Science ®Google Scholar
• GedikGKCağlarMUnalSGümrükFEvaluation of cardiovascular complications with 99mTc tetrofosmin gated myocardial perfusion scintigraphy in patients with thalassemia majorRev Esp Med Nucl208827319119818570861
   PubMed Web of Science ®Google Scholar
• TantawyAAAdlyAAEl MaatyMGAminSASubclinical atherosclerosis in young beta-thalassemia major patientsHemoglobin200933646347419958191
   PubMed Web of Science ®Google Scholar
• BrizziPIsajaTD’AgataAMalaguarneraLMalaguarneraMMusumeciSOxidized LDL antibodies (OLAB) in patients with beta-thalassemia majorJ Atheroscler Thromb20029313914412226555
   PubMedGoogle Scholar
• YuanXMBrunkUTIron and LDL-oxidation in atherogenesisAPMIS199810698258429808409
   PubMed Web of Science ®Google Scholar
• JacobHSNewly recognized causes of atherosclerosis: the role of microorganisms and of vascular iron overloadJ Lab Clin Med199412368088168201257
   PubMed Web of Science ®Google Scholar
• ValentiLSwinkelsDWBurdickLSerum ferritin levels are associated with vascular damage in patients with nonalcoholic fatty liver diseaseNutr Metab Cardiovasc Dis201121856857520392616
   PubMed Web of Science ®Google Scholar
• WalkerEMJrWalkerSMEffects of iron overload on the immune systemAnn Clin Lab Sci200030435436511045759
   PubMed Web of Science ®Google Scholar
• CantinieauxBBoelaertJRDe MeuleneireJKerrelsVFonduPNeutrophils from patients with secondary haemosiderosis contain excessive amounts of autotoxic ironEur J Haematol19935131611658405331
   PubMed Web of Science ®Google Scholar
• CardierJERomanoESoyanoAT lymphocytes subsets in experimental iron overloadImmunopharmacol Immunotoxicol199719175879049660
   PubMed Web of Science ®Google Scholar
• BallartIJEstevezMESenLProgressive dysfunction of monocytes associated with iron overload and age in patients with thalassemia majorBlood19866711051093940540
   PubMed Web of Science ®Google Scholar
• CantinieauxBJanssensABoelaertJRFerritin-associated iron induces neutrophil dysfunction in hemosiderosisJ Lab Clin Med1999133435336110218766
   PubMed Web of Science ®Google Scholar
• CardierJERomanoESoyanoALipid peroxidation and changes in T lymphocyte subsets and lymphocyte proliferative response in experimental iron overloadImmunopharmacol Immunotoxicol19951747057178537607
   PubMed Web of Science ®Google Scholar
• CantinieauxBBoelaertJHarigaCFonduPImpaired neutrophil defense against Yersinia enterocolitica in patients with iron overload who are undergoing dialysisJ Lab Clin Med198811155245283361231
   PubMed Web of Science ®Google Scholar
• van AsbeckBSVerbrughHAvan OostBAMarxJJImhofHWVerhoefJListeria monocytogenes meningitis and decreased phagocytosis associated with iron overloadBr Med J (Clin Res Ed)19822846315542544
   PubMed Web of Science ®Google Scholar
• BullenJJSpaldingPBWardCGGutteridgeJMHemochromatosis, iron and septicemia caused by Vibrio vulnificusArch Intern Med19911518160616091872665
   PubMedGoogle Scholar
• ReiterBBrockJHSteelEDInhibition of Escherichia coli by bovine colostrum and post-colostral milk. II. The bacteriostatic effect of lactoferrin on a serum susceptible and serum resistant strain of E. coliImmunology197528183951090522
   PubMed Web of Science ®Google Scholar
• LawrenceTHBiggersCJSimontonPRBacteriostatic inhibition of Klebsiella pneumoniae by three human transferrinsAnn Hum Biol197743281284332055
   PubMed Web of Science ®Google Scholar
• AbbottMGallowayACunninghamJLHaemochromatosis presenting with a double Yersinia infectionJ Infect19861321431453531350
   PubMed Web of Science ®Google Scholar
• CapronJPCapron-ChivracDTossouHDelamarreJEbFSpontaneous Yersinia enterocolitica peritonitis in idiopathic hemochromatosisGastroenterology1984876137213756489703
   PubMed Web of Science ®Google Scholar
• BrennanROCrainBJProctorAMDurackDTCunninghamella: a newly recognized cause of rhinocerebral mucormycosisAm J Clin Pathol1983801981026858971
   PubMed Web of Science ®Google Scholar
• GurselOKurekciAETascilarEPremature atherosclerosis in children with β-thalassemia majorJ Pediatr Hematol Oncol201234863063423108004
   PubMed Web of Science ®Google Scholar
• AngelucciEMurettoPLucarelliGTreatment of iron overload in the “ex-thalassemic”. Report from the phlebotomy programAnn N Y Acad Sci19988502882939668550
   PubMed Web of Science ®Google Scholar
• FlatenTPAasethJAndersenOKontoghiorghesGJIron mobilization using chelation and phlebotomyJ Trace Elem Med Biol2012262–312713022565013
   PubMed Web of Science ®Google Scholar
• BuscaAFaldaMManziniPIron overload in patients receiving allogeneic hematopoietic stem cell transplantation: quantification of iron burden by a superconducting quantum interference device (SQUID) and therapeutic effectiveness of phlebotomyBiol Blood Marrow Transplant201016111512219766730
   PubMed Web of Science ®Google Scholar
• MariottiEAngelucciEAgostiniABaroncianiDSgarbiELucarelliGEvaluation of cardiac status in iron-loaded thalassaemia patients following bone marrow transplantation: improvement in cardiac function during reduction in body iron burdenBr J Haematol199810349169219886301
   PubMed Web of Science ®Google Scholar
• MurettoPAngelucciELucarelliGReversibility of cirrhosis in patients cured of thalassemia by bone marrow transplantationAnn Intern Med2002136966767211992302
   PubMed Web of Science ®Google Scholar
• BodemannHHTanzi-FettaRFSchröter-UrbanHVolkBAKeulJLöhrGWFerritin in erythrocytes and plasma of patients with iron overloadBlut198551125313848335
   PubMedGoogle Scholar
• SharifiSMAfrasiabianHEvaluation of wet cupping treatment in patients with chronic urticaria and angioedemaOpen Conf Proc J2013315
   Google Scholar
• BahramiMAtaie-JafariAHosseiniSForuzanfarMHRahmaniMPajouhiMEffects of natural honey consumption in diabetic patients: an 8-week randomized clinical trialInt J Food Sci Nutr200960761862619817641
   PubMed Web of Science ®Google Scholar
• AbdulrhmanMEl-HefnawyMHusseinREl-GoudAAThe glycemic and peak incremental indices of honey, sucrose and glucose in patients with type 1 diabetes mellitus: effects on C-peptide level-a pilot studyActa Diabetol2011482899419941014
   PubMed Web of Science ®Google Scholar
• AgrawalOPPachauriAYadavHSubjects with impaired glucose tolerance exhibit a high degree of tolerance to honeyJ Med Food200710347347817887941
   PubMed Web of Science ®Google Scholar
• Al-WailiNSEffects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individualsJ Med Food20036213514012935325
   PubMedGoogle Scholar
• Al-WailiNSHaqAEffect of honey on antibody production against thymus-dependent and thymus-independent antigens in primary and secondary immune responsesJ Med Food20047449149415671696
   PubMed Web of Science ®Google Scholar
• Al-WailiNSAl-WailiTNAl-WailiANSaloomKSInfluence of natural honey on biochemical and hematological variables in AIDS: a case studyScientificWorldJournal200661985198917369997
   PubMed Web of Science ®Google Scholar
• LoukasMSaadYTubbsRSShojaMMThe heart and cardiovascular system in the Qur’an and HadeethInt J Cardiol20101401192319709769
   PubMed Web of Science ®Google Scholar
• Al-BukhariMIThe English Translation of Sahih Al Bukhari. Book of medicine. Chapter of (Cure is in three). Hadeeth numbers 5680–5681Assryia librarySayda, Lebanon2002
   Google Scholar
• CazzolaMBorgna-PignattiCde StefanoPInternal distribution of excess iron and sources of serum ferritin in patients with thalassemiaScand J Haematol19833042892966857145
   PubMedGoogle Scholar
• Di MarcoVCapraMGagliardottoFLiver disease in chelated transfusion-dependent thalassemics: the role of iron overload and chronic hepatitis CHaematologica20089381243124618556410
   PubMed Web of Science ®Google Scholar
• TriadouPRegnat-LusinchiAGirotRUse of the ferritin/alanine aspartate transaminase ratio as an iron overload marker independent of liver cell damageEur J Haematol19894354234272612615
   PubMed Web of Science ®Google Scholar
• WonkeBHoffbrandAVBrownDDusheikoGAntibody to hepatitis C virus in multiply transfused patients with thalassaemia majorJ Clin Pathol19904386386402119395
   PubMed Web of Science ®Google Scholar
• LaiMEOrigaRDanjouFNatural history of hepatitis C in thalassemia major: a long-term prospective studyEur J Haematol201390650150723414443
   PubMed Web of Science ®Google Scholar
• AlavianSMMiriSMTabatabaeiSVLipid Profiles and Hepatitis C Viral Markers in HCV-Infected Thalassemic PatientsGut Liver20115334835521927665
   PubMed Web of Science ®Google Scholar
• OmarNSalamaKAdolfSEl-SaeedGSAbdel GhaffarNEzzatNMajor risk of blood transfusion in hemolytic anemia patientsBlood Coagul Fibrinolysis201122428028421508832
   PubMed Web of Science ®Google Scholar
• AmeliMBesharatiSNematiKZamaniFRelationship between elevated liver enzyme with iron overload and viral hepatitis in thalassemia major patients in Northern IranSaudi Med J200829111611161518998011
   PubMed Web of Science ®Google Scholar
• RagabLHelalSZaghloulNClinicovirologic analysis of hepatitis C infection in transfusion-dependent beta-thalassemia major childrenInt J Lab Hematol201032218419019389113
   PubMed Web of Science ®Google Scholar
• SartoriMAndornoSLa TerraGEvaluation of iron status in patients with chronic hepatitis CItal J Gastroenterol Hepatol19983043964019789136
   PubMed Web of Science ®Google Scholar
• MazzaPGiuaRDe MarcoSIron overload in thalassemia: comparative analysis of magnetic resonance imaging, serum ferritin and iron content of the liverHaematologica19958053984048566878
   PubMed Web of Science ®Google Scholar
• AgarwalMBMalkanGHBhaveAAAntibody to hepatitis-C virus in multi-transfused thalassaemics – Indian experienceJ Assoc Physicians India19934141951978270554
   PubMedGoogle Scholar
• AlavianSMMiriSMKeshvariMDistribution of hepatitis C virus genotype in Iranian multiply transfused patients with thalassemiaTransfusion200949102195219919538541
   PubMed Web of Science ®Google Scholar
• HuYWAl-MoslihMIAl AliMTClinical outcome of frequent exposure to Torque Teno virus (TTV) through blood transfusion in thalassemia patients with or without hepatitis C virus (HCV) infectionJ Med Virol200880236537118098140
   PubMed Web of Science ®Google Scholar
• ChuWCMetreweliCChikKWLamWWChanYLLiCKEnlargement of hepatoduodenal ligament lymph nodes in beta thalassemia children receiving multiple transfusions: a common observationHaematologica200287888288412161366
   PubMed Web of Science ®Google Scholar
• TabatabaeiSVAlavianSMKeshvariMLow dose ribavirin for treatment of hepatitis C virus infected thalassemia major patients; new indications for combination therapyHepat Mon201212637238122879826
   PubMed Web of Science ®Google Scholar
• SpiliopoulouIRepantiMKatinakisSKarana-GinopoulouAPapanastasiouDAResponse to interferon alfa-2b therapy in mutitransfused children with beta-thalassemia and chronic hepatitis CEur J Clin Microbiol Infect Dis1999181070971510584897
   PubMed Web of Science ®Google Scholar
• TelferPTGarsonJAWhitbyKCombination therapy with interferon alpha and ribavirin for chronic hepatitis C virus infection in thalassaemic patientsBr J Haematol19979848508559326177
   PubMed Web of Science ®Google Scholar
• ChoiEYKimECOhHMIron chelator triggers inflammatory signals in human intestinal epithelial cells: involvement of p38 and extracellular signal-regulated kinase signaling pathwaysJ Immunol2004172117069707715153529
   PubMed Web of Science ®Google Scholar
• LeeHJLeeJLeeSKLeeSKKimECDifferential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytesBMC Cancer2007717617850672
   PubMed Web of Science ®Google Scholar
• BrittenhamGMNathanDGOlivieriNFDeferiprone and hepatic fibrosisBlood2003101125089509012788794
   PubMed Web of Science ®Google Scholar