322
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

In-vivo Wound Healing and Anti-Inflammatory Activity of the Solvent Fraction of Zehneria scabra L.F. Sond (Cucurbitaceae) Leaves

ORCID Icon, ORCID Icon, ORCID Icon, & ORCID Icon
Pages 367-377 | Received 31 Aug 2022, Accepted 29 Nov 2022, Published online: 02 Dec 2022

References

  • Masson‐Meyers DS, Andrade TA, Caetano GF, et al. Experimental models and methods for cutaneous wound healing assessment. Int J Exp Pathol. 2020;101(1–2):21–37. doi:10.1111/iep.12346
  • Nguyen DT, Orgill DP, Murphy GF. The pathophysiologic basis for wound healing and cutaneous regeneration. In: Biomaterials for Treating Skin Loss. Woodhead Publishing; 2009:25–57.
  • Nahla Saeed IA Evaluation of gastro protective effect and wound healing potential of cibotium barometz and vitex pubecsens in an animal model/Nahla Saeed Ibraheem Alwajeeh Doctoral dissertation. University of Malaya; 2017.
  • Muluye AB, Desta AG, Abate SK, et al. Anti-malarial activity of the root extract of Euphorbia abyssinica (Euphorbiaceae) against Plasmodium berghei infection in mice. Malar J. 2019;18:261. doi:10.1186/s12936-019-2887-7
  • Atkin L. Understanding methods of wound debridement. Br J Nurs. 2014;23(12):S10–S5. doi:10.12968/bjon.2014.23.sup12.S10
  • García-Villén F, Faccendini A, Aguzzi C, et al. Montmorillonit- norfloxacin nanocomposite intended for healing of infected wounds. Int J Nanomedicine. 2019;14:5051–5060. doi:10.2147/IJN.S208713
  • Hamdan S, Pastar I, Drakulich S, et al. Nanotechnology-driven therapeutic interventions in wound healing: potential uses and applications. ACS Cent Sci. 2017;3(3):163–175. doi:10.1021/acscentsci.6b00371
  • Agyare C, Boakye YD, Bekoe EO, Hensel A, Dapaah SO, Appiah T. African medicinal plants with wound healing properties. J Ethnopharmacol. 2016;11(177):85–100. doi:10.1016/j.jep.2015.11.008
  • Gedif T, Hahn HJ. The use of medicinal plants in self-care in rural central Ethiopia. J Ethnopharmacol. 2003;87(2–3):155–161. doi:10.1016/S0378-8741(03)00109-0
  • Teklay A, Abera B, Giday M. An ethnobotanical study of medicinal plants used in kilte awulaelo district, tigray region of Ethiopia. J Ethnobiol Ethnomed. 2013;9(1):1–23. doi:10.1186/1746-4269-9-65
  • Tekle Y. An ethno-veterinary botanical survey of medicinal plants in Kochore district of Gedeo zone, southern nations nationalities and peoples regional state (SNNPRs), Ethiopia. J Sci Innov Res. 2014;3(4):433–445. doi:10.31254/jsir.2014.3407
  • Kefalew A, Asfaw Z, Kelbessa E. Ethnobotany of medicinal plants in Ada’a District, East Shewa Zone of Oromia regional state, Ethiopia. J Ethnobiol Ethnomed. 2015;11(1):1–28. doi:10.1186/s13002-015-0014-6
  • Abew B, Sahile S, Moges F. In vitro antibacterial activity of leaf extracts of Z. scabra and Ricinus communis against Escherichia coli and methicillin resistance Staphylococcus aureus. Asian Pac J Trop Biomed. 2014;4(10):816–820. doi:10.12980/APJTB.4.201414B16
  • Agogbua J, Ekeke C, Okoli BE. Morpho-anatomical characters of Zehneria capillacea (Schumach) C. Jeffrey and Z. scabra (LF) Sond Cucurbitaceae. Afr J Plant Sci. 2015;9(12):457–465. doi:10.5897/AJPS2015.1306
  • Murthy KS, Ravindranath D, Sandhya RS, Pullaiah T. Ethnobotany and distribution of wild and cultivated genetic resources of Cucurbitaceae in the Eastern Ghats of Peninsular India. Top Class J Herbal Med. 2013;2(6):149–158.
  • Ragunathan M, Abay SM. Ethnomedicinal survey of folk drugs used in Bahirdar Zuria district, Northwestern Ethiopia; 2009.
  • Nureye D, Tekalign E, Fisseha N, Tesfaye T, Hammeso WW. Evaluation of antiplasmodial activity of hydroalcoholic crude extract and solvent fractions of Z. scabra roots against plasmodium berghei in Swiss albino mice. Infect Drug Resist. 2021;14:2583. doi:10.2147/IDR.S314262
  • Council NR. Guide for the Care and Use of Laboratory Animals. Washington, DC, USA: National Academies Press; 2010.
  • Tekleyes B, Huluka SA, Wondu K, Wondmkun YT. Wound healing activity of 80 percent methanol leaf extract of Z. scabra (Lf) sond (cucurbitaceae) in mice. J Exp Pharmacol. 2021;13:537. doi:10.2147/JEP.S303808
  • Beshir K. Evaluation of wound healing activity of 70 percent ethanol leaf extract of becium grandiflorum lam. (Lamiaceae) in Mice. Addis Ababa, Ethiopia: Addis Ababa University; 2017.
  • Geetha TS, Geetha N. Phytochemical screening, quantitative analysis of primary and secondary metabolites of Cymbopogan citratus (DC) Stapf. Leaves from Kodaikanal Hills, Tamilnadu. Int J Pharmtech Res. 2014;6(2):521–529.
  • Wadood A, Ghufran M, Jamal SB, Naeem M, Khan A, Ghaffar R. Phytochemical analysis of medicinal plants occurring in local area of Mardan. Biochem Anal Biochem. 2013;2(4):1–4. doi:10.4172/2161-1009.1000144
  • Mulisa E, Asres K, Engidawork E. Evaluation of wound healing and anti-inflammatory activity of the rhizomes of Rumex abyssinicus J. (Polygonaceae) in mice. BMC Complement Altern Med. 2015;15(1):341. doi:10.1186/s12906-015-0878-y
  • Belachew TF, Asrade S, Geta M, Fentahun E. In vivo evaluation of wound healing and anti-inflammatory activity of 80% methanol crude flower extract of hagenia abyssinica (Bruce) J.F. Gmel in Mice. Evid-Based Complement Altern Med. 2020;2020:1–12. doi:10.1155/2020/9645792
  • Lambebo MK, Kifle ZD, Gurji TB, Yesuf JS. Evaluation of wound healing activity of methanolic crude extract and solvent fractions of the leaves of vernonia auriculifera hiern (asteraceae) in mice. J Exp Pharmacol. 2021;13:677. doi:10.2147/JEP.S308303
  • Ambikar D, Tsegaw A, Belayneh YM, Belayneh YM. Wound healing activity of 80 percent methanolic crude extract and solvent fractions of the leaves of justicia schimperiana (Hochst. ex Nees) T. Anderson (Acanthaceae) in Mice. J Exp Pharmacol. 2022;14:167. doi:10.2147/JEP.S340177
  • Upadhyay A, Chattopadhyay P, Goyary D, Mitra Mazumder P, Veer V. Ixora coccinea enhances cutaneous wound healing by upregulating the expression of collagen and basic fibroblast growth factor. ISRN Pharmacol. 2014;2014:w356. doi:10.1155/2014/751824
  • Mekonnen A, Sidamo T, Asres K, Engidawork E. In vivo wound healing activity and phytochemical screening of the crude extract and various fractions of Kalanchoe petitiana A. Rich (Crassulaceae) leaves in mice. J Ethnopharmacol. 2013;145(2):638–646. doi:10.1016/j.jep.2012.12.002
  • Assefa A, Urga K, Melaku D, Guta M, Mekonnen W. Bronchodilator and anti-inflammatory activities of Adhatoda schimperiana. Ethiop J Health Sci. 2008;18:2.
  • Robert JN, Els N, Danny EC, Petra GB, Klaske N, Paul L. Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr. 2001;74:418–425. doi:10.1093/ajcn/74.4.418
  • Mekonnen NA, Atnafie AS, Atta WM. Evaluation of the anti-inflammatory activities of 70 percent ethanol leaves extract and solvent fractions of Z. scabra (Lf) Sond (Cucurbitaceae) in rodents. Evid-Based Complement Altern Med. 2020;2020:11.
  • Umer S, Asres K, Veeresham C. Hepatoprotective activities of two Ethiopian medicinal plants. Pharm Biol. 2010;48(4):461–468. doi:10.3109/13880200903173593
  • Sagbo IJ, Afolayan AJ, Bradley G. Antioxidant, antibacterial and phytochemical properties of two medicinal plants against the wound infecting bacteria. Asian Pac J Trop Biomed. 2017;7(9):817–825. doi:10.1016/j.apjtb.2017.08.009
  • Ali A, Alam S, Ahmad S, Ali S, Ahsan M, Siddiqui W. Wound healing activity of alcoholic extract of Tamarix aphylla L. on animal models. Biomed Pharmacol J. 2019;12(1):41–48. doi:10.13005/bpj/1611
  • Arun M, Satish S, Anima P. Evaluation of wound healing, antioxidant and antimicrobial efficacy of Jasminum auriculatum Vahl. leaves. Avicenna J Phytome. 2016;6(3):295.
  • Samanta R, Pattnaik AK, Pradhan KK, Mehta BK, Pattanayak SP, Banerjee S. Wound healing activity of silibinin in mice. Pharmacognosy Res. 2016;8(4):298. doi:10.4103/0974-8490.188880
  • Samejo MQ, Sumbul A, Shah S, Memon SB, Chundrigar S. Phytochemical screening of Tamarix dioica Roxb. ex Roch. J Pharm Res. 2013;7(2):181–183. doi:10.1016/j.jopr.2013.02.017
  • Institute of Laboratory Animal Resources (US). Committee on Care, Use of Laboratory Animals. In: Guide for the Care and Use of Laboratory Animals. US Department of Health and Human Services, Public Health Service, National Institutes of Health; 1986.