9,281
Views
663
CrossRef citations to date
0
Altmetric
Review

Hepatocellular carcinoma: a review

, , , , , , , & show all
Pages 41-53 | Published online: 05 Oct 2016

References

  • Center for Disease Control and Prevention (CDC)Hepatocellular carcinoma-United States 2001–2006MMWR Morb Mortal Wkly Rep2010591751752020448528
  • CrissienAMFrenetteCCurrent Management of hepatocellular carcinomaGastroenterol Hepatol2014103153161
  • FerlayJShinHRBrayFFormanDMathersCParkinDMEstimates of worldwide burden of cancer in 2008: GLOBOCAN 2008Int J Cancer2010127122893297121351269
  • AltekruseSFMcGlynnKAReichmanMEHepatocellular carcinoma incidence, mortality and survival trends in the United States from 1975 to 2005J Clin Oncol2009271485149119224838
  • BruixJShermanMAASLD Practice Guidelines: management of hepatocellular carcinoma: an updateHepatology2010135
  • OttJJStevensGAGroegerJWiersmaSTGlobal epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicityVaccine201230122212221922273662
  • International Agency for Research on Cancer (IARC)Monographs on the evaluation of carcinogenic risks to humansHepatitis Viruses199459182221
  • McMahonBJThe natural history of chronic hepatitis B virus infectionHepatology2009495S45S5519399792
  • ChenGLinWShenFIloejeUHLondonWTEvansAAPast HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective studyAm J Gastroenterol200610181797180316817842
  • HosakaTSuzukiFKobayashiMLong-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infectionHepatology20135819810723213040
  • ChiangC-JYangY-WYouS-LLaiM-SChenC-JThirty-year outcomes of the national hepatitis B immunization program in TaiwanJAMA2013310997497624002285
  • GoldsteinSTZhouFHadlerSCBellBPMastEEMargolisHSA mathematical model to estimate global hepatitis B disease burden and vaccination impactInt J Epidemiol20053461329133916249217
  • DengMZhouXGaoSThe effects of telbivudine in late pregnancy to prevent intrauterine transmission of the hepatitis B virus: a systematic review and meta-analysisVirol J2012918522947333
  • WuQHuangHSunXTelbivudine prevents vertical transmission of hepatitis B virus from women with high viral loads: a prospective long-term studyClin Gastroenterol Hepatol20151361170117625251571
  • ChooQLRichmanKHHanJHGenetic organization and diversity of the hepatitis C virusProc Natl Acad Sci U S A1991886245124551848704
  • BostanNMahmoodTAn overview about hepatitis C: a devastating virusCrit Rev Microbiol20103629113320345213
  • AshamEHKasebAGhobrialRMManagement of hepatocellular carcinomaSurg Clin North Am201391423145024206860
  • LokASSeeffLBMorganTRIncidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver diseaseGastroenterology2009136113814818848939
  • GaoCFangLZhaoHCLiJTYaoSKPotential role of diabetes mellitus in the progression of cirrhosis to hepatocellular carcinoma: a cross-sectional case-control study from Chinese patients with HBV infectionHepatobiliary Pancreat Dis Int201312438539323924496
  • PuotiMBrunoRSorianoVHepatocellular carcinoma in HIV-infected patients: epidemiological features, clinical presentation and outcomeAIDS200418172285229315577541
  • SingalAKAnandBSMechanisms of synergy between alcohol and hepatitis C virusJ Clin Gastroenterol200741876177217700425
  • MorganRLBaackBSmithBDYartelAPitasiMFalck-YtterYEradication of hepatitis C virus infection and the development of hepatocellular carcinoma: a meta-analysis of observational studiesAnn Intern Med2013158532933723460056
  • International Agency for Research on Cancer (IARC)Monographs on the evaluation of carcinogenic risks to humansAlcohol Drinking19984444207215
  • BateyRGBurnsTBensonRJBythKAlcohol consumption and the risk of cirrhosisMed J Aust19921564134161545749
  • MorganTRMandayamSJamalMMAlcohol and hepatocellular carcinomaGastroenterology20041275S87S9615508108
  • JewellJSheronNTrends in European liver death rates: implications for alcohol policyClin Med2010103259263
  • BrechotCNalpasBFeitelsonMAInteractions between alcohol and hepatitis viruses in the liverClin Lab Med1996162732878792072
  • HassanMMHwangLYHattenCJRisk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitusHepatology20023651206121312395331
  • TuratiFGaleoneCRotaMAlcohol and liver cancer: a systematic review and meta-analysis of prospective studiesAnn Oncol20142581526153524631946
  • RinellaMENonalcoholic fatty liver disease: a systematic reviewJAMA2015313222263227326057287
  • WangCWangXGongGIncreased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta-analysis of cohort studiesInt J Cancer201213071639164821544812
  • WongRJCheungRAhmedANonalcoholic steatohepatitis is the most rapidly growing indication for liver transplantation in patients with hepatocellular carcinoma in the U.SHepatology20145962188219524375711
  • El-SeragHBHampelHJavadiFThe association between diabetes and hepatocellular carcinoma: a systemic review of epidemiologic evidenceClin Gastroenterol Hepatol2006436938016527702
  • MooreMAParkCBTsudaHImplications of the hyperinsulinaemia-diabetes-cancer link for preventive effortsEur J Cancer Prev199872891079818771
  • BalkauBKahnHCourbonDEschwegeEDucimetierePParis Prospective StudyHyperinsulinemia predicts fatal liver cancer but is inversely associated with fatal cancer at some other sites: the Paris Prospective StudyDiabetes Care200124584384911347741
  • CalleeEERodriguezCWalker-ThurmondKThunMJOverweight, obesity and mortality from cancer in a prospective studied cohort of US adultsN Engl J Med20033481625163812711737
  • ReddyJKRaoMSLipid metabolism and liver inflammationAm J Physiol Gastrointest Liver Physiol2006290G852G85816603729
  • LarsonSCWolkAOverweight, obesity and risk of liver cancer: a meta-analysis of cohort studiesBr J Cancer2007971005100817700568
  • MonsourHPAshamEMcFaddenRSVictorDWMuthuswamyBZaheerIHepatocellular carcinoma: the rising tide from east to west – a review of epidemiology, screening and tumor markersTransl Cancer Res201326492506
  • WakaiTShiraiYSakataJKoritaPVAjiokaYHatakeyamaKSurgical outcomes for hepatocellular carcinoma in nonalcoholic fatty liver diseaseJ Gastrointest Surg20111581450145821512848
  • TokushigeKHashimotoEYatsujiSProspective study of hepatocellular carcinoma in nonalcoholic steatohepatitis in comparison with hepatocellular carcinoma caused by chronic hepatitis CJ Gastroenterol201045996096720376504
  • WhiteDLEpidemiology of hepatocellular carcinomaCarrBIHepatocelluar CarcinomaNew York, NYHumana Press2010125
  • YuanJ-MRossRStanczykFZA cohort study of serum testosterone and hepatocellular carcinoma in Shanghai, ChinaInt J Cancer19956344914937591255
  • WhiteDLTavakoli-TabasiSKuzniarekJPascuaRRamseyDJEl-SeragHBHigher serum testosterone is associated with increased risk of advanced hepatitis C-related liver disease in malesHepatology201255375976821858849
  • LiuYWuFGlobal burden of aflatoxin-induced hepatocellular carcinoma: a risk assessmentEnviron Health Perspect2010118681882420172840
  • ChenJGEgnerPANgDReduced aflatoxin exposure presages decline in liver cancer mortality in an endemic region of ChinaCancer Prev Res201361010381045
  • KoCSiddaiahNBergerJPrevalence of hepatic iron overload and association with hepatocellular cancer in end-stage liver disease: results from the National Hemochromatosis Transplant RegistryLiver Int200727101394140117927713
  • DeugnierYTurlinBIron and hepatocellular carcinomaJ Gastroenterol Hepatol200116549149411350542
  • GandiniSBotteriEIodiceSBoniolMLowenfelsARMaisonneuvePTobacco smoking and cancer: a meta-analysisInt J Cancer200812215516417893872
  • MaheshwariSSarrajAKramerJEl-SeragHBOral contraception and the risk of hepatocellular carcinomaJ Hepatol20074750651317462781
  • van MeerSde ManRACoenraadMJSurveillance for hepatocellular carcinoma is associated with increased survival: results from a large cohort in the NetherlandsJ Hepatol20156351156116326100498
  • ZhangBHYangBHTangZYRandomized controlled trial of screening for hepatocellular carcinomaJ Cancer Res Clin Oncol2004130741742215042359
  • BruixJShermanMAmerican Association for the Study of Liver DiseasesAASLD Practice Guideline: management of hepatocellular carcinoma: an updateHepatology20115321020102221374666
  • TrevisaniFSantiVGramenziASurveillance for early diagnosis of hepatocellular carcinoma: is it effective in intermediate/advanced cirrhosis?Am J Gastroenterol20071021122482257
  • MasuzakiROmataMScreening program in high-risk populationsHepatocellular Carcinoma20115568
  • LokASHeathcoteEJHoofnagleJHManagement of hepatitis B: 2000 – summary of a workshopGastroenterology200112071828185311375963
  • KewMCMacerolloPEffect of age on the etiologic role of the hepatitis B virus in hepatocellular carcinoma in blacksGastroenterology19889424394422446950
  • YuMWChangHCLiawYFFamilial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relativesJ Natl Cancer Inst200092141159116410904089
  • TakashimaTMatsuiOSuzukiMIdaMDiagnosis and screening of small hepatocellular carcinomas. Comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and α1-fetoprotein assayRadiology19821456356386183708
  • PetersonMSBaronRLRadiologica diagnosis of hepatocellular carcinomaClin Liver Dis20015112314411218911
  • BolondiLSofiaSSiringoSSurveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysisGut200148225125911156649
  • AchkarJPArayaVBaronRLMarshJWDvorchikIRakelaJUndetected hepatocellular carcinoma: clinical features and outcomes after liver transplantationLiver Transpl Surg199844774829791158
  • BraheeDDOgedegbeCHasslerCBody mass index and abdominal ultrasound image quality: a pilot survey of sonographersJ Diagn Med Sonogr20132926672
  • WaldCRussoMWHeimbachJKHussainHKPomfretEABruixJNew OPTN/UNOS policy for liver transplant allocation: standardization of imaging, diagnosis, classification, and reporting of hepatocellular carcinomaRadiology2013266237638223362092
  • ColliAFraquelliMCasazzaGAccuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: a systematic reviewAm J Gastroenterol2006101351352316542288
  • CollierJShermanMScreening for hepatocellular carcinomaHepatology1998272732789425947
  • ShermanMPeltekianKMLeeCScreening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: incidence and prevelance of hepatocellular carcinoma in a North American urban populationHepatology1995224324387543434
  • TrevisaniFD’IntinoPEMorselli-LabateAMSerum α-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV statusJ Hepatol200134457057511394657
  • Gambarin-GelwanMWolfDCShapiroRSchwartzMEMinADSensitivity of commonly available screening tests in detecting hepatocellular carcinoma in hepatitis C virus cirrhosisHepatology20009515351538
  • Di BisceglieAMSterlingRKChungRTSerum α-fetoprotein levels in patients with advanced hepatitis C: results from the HALT-C TrialJ Hepat2005433434441
  • NguyenMHGarciaRTSimpsonPWWrightTLKeeffeEBRacial differences in effectiveness of alpha-fetoprotein for diagnosis of hepatocellular carcinoma in hepatitis C virus cirrhosisHepatology200236241041712143050
  • LinOSKeeffeEBSandersGDOwensDKCost-effectiveness of screening for hepatocellular carcinoma in patients with cirrhosis due to chronic hepatitis CAliment Pharmacol Ther200419111159117215153169
  • KhienVVMaoHVChinhTTClinical evaluation of lentil lectin-reactive alpha-fetoprotein-L3 in histology-proven hepatocellular carcinomaInt J Biol Markers200116210511111471892
  • IshiiMGamaHChidaNSimultaneous measurements of serum α-fetoprotein and protein induced by vitamin K absence for detecting hepatocellular carcinoma. South Tohoku District Study GroupAm J Gastroenterol20009541036104010763956
  • MarreroJASuGLWeiWDes-γ carboxyprothrombin can differentiate hepatocellular carcinoma from nonmalignant chronic liver disease in American patientsHepatology20033751114112112717392
  • SinghalAJayaramanMDhanasekaranDNKohliVMolecular and serum markers in hepatocellular carcinoma: predictive tools for prognosis and recurrenceCrit Rev Oncol Hematol201282211614021680198
  • SangiovanniAManiniMAIavaroneMThe diagnostic and economic impact of contrast imaging techniques in the diagnosis of small hepatocellular carcinoma in cirrhosisGut20105963864419951909
  • LeeYJLeeJMLeeJSHepatocellular carcinoma: diagnostic performance of multidetector CT and MR imaging – a systematic review and meta-analysisRadiology20152759710925559230
  • El-SeragHBHepatocellular carcinomaN Engl J Med20113651118112721992124
  • VerslypeCRosmorducORougierPESMO Guidelines Working GroupHepatocellular carcinoma: ESMO-ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-upAnn Oncol2012237vii42vii48
  • NathanHPawlikTMStaging of hepatocellular carcinomaMastersKMVautheyJ-NHepatocellular CarcinomaBerlin, GermanySpringer6980
  • HuoTILinHCHsiaCYThe model for end-stage liver disease based cancer staging systems are better prognostic models for hepatocellular carcinoma: a prospective sequential surveyAm J Gastroenterol20071021920193017573792
  • KamathPSWiesnerRHMalinchocMA model to predict survival in patients with end-stage liver diseaseHepatology200133246447011172350
  • VautheyJNLauwersGYEsnaolaNFSimplified staging for hepatocellular carcinomaJ Clin Oncol20022061527153611896101
  • FlemingIDAJCC/TNM cancer staging for hepatocellular carcinomaJ Surg Oncol20017723323611473370
  • SanyalAPoklepovicAMoyneurEBargoutV(2010). Population-based risk factors and resource utilization for HCC: US perspectiveCurr Med Res Opin20102692183219120666689
  • SingalAGNehraMAdams-HuetB(2013). Detection of hepatocellular carcinoma at advanced stages among patients in the HALT-C trial: where did surveillance fail?Am J Gastroenterol2013108342543223337478
  • FornerRMRodriguez de LopeCBruixJCurrent strategy for staging and treatment: the BCLC update and future prospectsSemin Liver Dis201030617420175034
  • AllemannPDemartinesNBouzoureneHTempiaAHalkicNLong-term outcome after liver resection for hepatocellular carcinoma larger than 10 cmWorld J Surg201337245245823188527
  • WongRFrenetteCUpdates in the management of hepatocellular carcinomaGastroenterol Hepatol2011711624
  • IshizawaTHasegawaAAokiTNeither multiple tumors nor portal hypertension are surgical contraindications for hepatocellular carcinomaGastroenterology200813471908191618549877
  • RoayaieSHaimMBEmreSComparison of surgical outcomes for hepatocellular carcinoma in patients with hepatitis B versus hepatitis C: a western experienceAnn Surg Oncol200071076477011129425
  • ColleoniMAudisioRADe BraudFFazioNMartinelliGGoldhirshAPractical considerations in treatment of hepatocellular carcinomaDrugs19985533673829530543
  • D’AmicoGGarcia-TsaoGPagliaroLNatural history and prognostic indicators of survival in cirrhosis: a systemic review of 118 studiesJ Hepatol20064421723116298014
  • TehSHChristeinJDonohueJHepatic resection of hepatocellular carcinoma in patients with cirrhosis: model of end-stage liver disease (MELD) score predicts perioperative mortalityJ Gastrointest Surg2005991207121516332475
  • BelghitiJKianmaneshRSurgical treatment of hepatocellular carcinomaHPB20057424918333160
  • AbulkhirALimongelliPHealeyAJPreoperative portal vein embolization for major liver resection: a meta-analysisAnn Surg20082471495718156923
  • PalavecinoMChunYSMadoffDCMajor hepatic resection for hepatocellular carcinoma with or without portal vein embolization: perioperative outcome and survivalSurgery2009145439940519303988
  • PoonRTFanSTLoCMLiuCIWongJLong-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: implications for a strategy of salvage transplantationAnn Surg200223537338211882759
  • TosoCTrotterJWeiATotal tumor volume predicts risk of recurrence following liver transplantation in patients with hepatocellular carcinomaLiver Transpl2007711071115
  • RimassaLSantoroASorafenib therapy in advanced hepatocellular carcinoma: the SHARP trialExpert Rev Anticancer Ther20099673974519496710
  • HagiwaraSKudoMNagaiTActivation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinomaBr J Cancer20121061997200322596232
  • AuJSFrenetteCT(2015). Management of hepatocellular carcinoma: current status and future directionsGut Liver20159443744826087860
  • ImamuraHMatsuyamaYTanakaERisk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomyJ Hepatol20033820020712547409
  • VivarelliMMontaltiRRisalitiAMultimodal treatment of hepatocellular carcinoma on cirrhois: an updateWorld J Gastroenterol201319427316732624259963
  • TorzilliGMakuuchiMInoueKNo-mortality liver resection for hepatocellular carcinoma in cirrhotic and noncirrhotic patients: is there a way? A prospective analysis of our approachArch Surg1999134998499210487594
  • FanSTLoCMLiuCLHepatectomy for hepatocellular carcinoma: toward zero hospital deathsAnn Surg199922932233010077043
  • AbdallaEKDenysAHasegawaKTreatment of large and advanced hepatocellular carcinomaAnn Surg Oncol200815497998518236115
  • CapussottiLFerreroAViganoLPolastriRTaboneMLiver resection for HCC with cirrhosis: surgical perspectives out of EASL/AASLD guidelinesEur J Surg Oncol200935111517689043
  • CherquiDLaurentAMocellinNLiver resection for transplantable hepatocellular carcinoma: long-term survival and role of secondary liver transplantationAnn Surg2009250573874619801927
  • ChaCHRuoLFongYResection of hepatocellular carcinoma in patients otherwise eligible for transplantationAnn Surg2003238231532314501497
  • ViganoLCherquiDLaparoscopic liver resection for HCC: a European perspectiveHepatocellular CarcinomaBerlin, GermanySpringer2011185206
  • MazzaferroVRegaliaEDociRLiver transplantation for the treatment of small hepatocellular carcinoma in patients with cirrhosisN Engl J Med1996334116936998594428
  • MazzaferroVBhooriSSpositoCMilan criteria in liver transplantation for hepatocellular carcinoma: an evidence-based analysis of 15 years of experienceLiver Transpl2011172S44S5721695773
  • YaoFYFerrellLBassNMLiver transplantation for hepatocellular carcinoma: expansion of tumor size limits does not adversly impact survivalHepatology2001331394140311391528
  • DuBayDSandroussiCSandhuLLiver transplantation for advanced hepatocellular carcinoma using poor tumor differentiation on biopsy as an exclusion criteriaAnn Surg201125316617221294289
  • YaoFYExpanded criteria for hepatocellular carcinoma: down-staging with a view to liver transplantation – yesSemin Liver Dis200626323924716850373
  • YaoFYHiroseRLaBergeJMA prospective study on downstaging of hepatocellular carcinoma prior to liver transplantationLiver Transpl200511121505151416315294
  • YaoFYKerlanRKHiroseR(2008). Excellent outcomes following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysisHepatology200848381982718688876
  • US Department of Health and Human Services, Health Resources and Services Administration, Organ Procurement and Transplantation Network (n.d.). Retrieved January 1, 2015. Available from: http://optn.transplant.hrsa.gov/policiesAndBylaws/policies.aspAccessed May 19, 2016
  • MancusoAManagement of hepatocellular carcinoma: enlightening the gray zonesWorld J Hepatol20135630231023805354
  • TakayasuKAriiSIkaiIProspective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8,510 patientsGastroenterology200613146146916890600
  • SchwartzMRoayaieSKonstadoulakisMStrategies for the management of hepatocellular carcinomaNat Clin Pract Oncol2007442443217597707
  • LewandowskiRJGeschwindJFLiapiESalemRTranscatheter intraarterial therapies: rationale and overviewRadiology2011259364165721602502
  • LammerJMalagariKVoglTProspective randomized study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of PRECISION V studyCardiovasc Intervent Radiol2010331415219908093
  • RaoulJLSangroBFornerAEvolving strategies for the management of intermediate-stage hepatocellular carcinoma: available evidence and expert opinion on the use of transarterial chemoembolizationCancer Treat Rev201137321222020724077
  • LlovetJMRealMIMontanaXArterial embolization or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomized controlled trialLancet200235993191734173912049862
  • LlovetJMBruixJSystematic review of randomized trials for unresectable hepatocellular carcinomaHepatology200337242944212540794
  • TinkleCLHaas-KoganDHepatocellular carcinoma:natural history, current management, and emerging toolsBiologics2012620721922904613
  • YuSJKimYJEffective treatment strategies other than sorafenib for the patients with advanced hepatocellular carcinoma invading portal veinWorld J Hepatol20157111553156126085914
  • RaoulJLGuyaderDBretagneJFProspective randomized trial of chemoembolization versus intra-arterial injection of 131I-labeled-iodized oil in the treatment of hepatocellular carcinomaHepatology199726115611619362356
  • SangroBCarpaneseLCianniRSurvival after yttrium-90 resin microsphere radioembolization of hepatocellular carcinoma across Barcelona liver cancer stages: a European evaluationHepatology201154386887821618574
  • VenteMAWondergamMvan der TweelIYttrium-90 micro-sphere radioembolization for the treatment of liver malignancies: a structured meta-analysisEur Radiol20091995195918989675
  • KulikLMCarrBIMulcahyMFSafety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosisHepatology2008471718118027884
  • RiazAKulikLLewandowskiRJRadiologic-pathologic correlation of hepatocellular carcinoma treated with internal radiation using yttirum-90 microspheresHepatology2009491185119319133645
  • LivraghiTMeloniFDi StasiMSustained complete response and complications rates after radiofrequncy ablation of very early hepatocellular carcinoma in cirrhosis: is resection still the treatment of choice?Hepatology200847828918008357
  • LencioniRCioniDCrocettiLEarly-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablationRadiology200523496196715665226
  • BertotLCSatoMTateishiRYoshidaHKoikeKMortality and complication rates of percutaneous ablative techniques for the treatment of liver tumors: a systemic reviewEur Radiol2011212584259621858539
  • LlovetJMRicciSMazzaferroVSorefenib in advanced hepatocellular carcinomaN Engl J Med2008359437839018650514
  • ChengALKangYKChenZEfficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomized, double-blind, placebo controlled trialLancet Oncol2009101253419095497
  • BruixJRaoulJ-LShermanMEfficiancy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalysis of a phase III trialJ Hepatol20125782182922727733
  • European Association For The Study Of The Liver, European Organisation For Research And Treatment Of CancerEASL-EORTC clinical practice guidelines: management of hepatocellular carcinomaJ Hepatol20125690894322424438
  • IavaroneMCabibboGPiscagliaFField-practice study of sorafenib therapy for hepatocellular carcinoma: a prospective multicenter study in ItalyHepatology20115462055206321898496
  • SohalDPSunWHepatocellular carcinoma: prevention and therapyCurr Oncol Rep201113318619421409527
  • Cochrane MillerJBridging procedures prior to liver transplantationRadiology Rounds2015131