79
Views
17
CrossRef citations to date
0
Altmetric
Original Research

The treatment of nonunions with application of BMP-7 increases the expression pattern for angiogenic and inflammable cytokines: a matched pair analysis

, , , , , , , , , & show all
Pages 155-165 | Published online: 22 Sep 2016

References

  • GiannoudisPVEinhornTAMarshDFracture healing: the diamond conceptInjury200738suppl 4S3S6
  • TakemotoRFormanJTaorminaDPEgolKANo advantage to rhBMP-2 in addition to autogenous graft for fracture nonunionOrthopedics2014376e525e53024972432
  • SchmidmaierGSchwabePWildemannBHaasNPUse of bone morphogenetic proteins for treatment of non-unions and future perspectivesInjury200738suppl 4S35S4118224735
  • GiannoudisPVEinhornTASchmidmaierGMarshDThe diamond concept – open questionsInjury200839suppl 2S5S818804574
  • ZimmermannGMoghaddamAReumannMTGF-β1 als pathophysiologischer Faktor bei der Frakturheilung [TGF-beta1 as a pathophysiological factor in fracture healing]Unfallchirurg20071102130136 German17160396
  • DoneganDJScolaroJMatuszewskiPEMehtaSStaged bone grafting following placement of an antibiotic spacer block for the management of segmental long bone defectsOrthopedics20113411e730e73522049954
  • MoghaddamAZietzschmannSBrucknerTSchmidmaierGTreatment of atrophic tibia non-unions according to ‘diamond concept’: results of one- and two-step treatmentInjury201546suppl 4S39S5026542865
  • SchmidmaierGMoghaddamAPseudarthrosen langer Röhrenknochen [Long Bone Nonunion]Z Orthop Unfall20151536659676 German26670151
  • ChristouCOliverRAYuYWalshWRThe Masquelet technique for membrane induction and the healing of ovine critical sized segmental defectsPLoS One2014912e11412225461340
  • GautschiOPFreySPZellwegerRBone morphogenetic proteins in clinical applicationsANZ J Surg200777862663117635273
  • BorrelliJJrPrickettWDRicciWMTreatment of nonunions and osseous defects with bone graft and calcium sulfateClin Orthop Relat Res200341124525412782881
  • ChoTJGerstenfeldLCEinhornTADifferential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healingJ Bone Miner Res200217351352011874242
  • GiannoudisPVKanakarisNKDimitriouRGillIKolimaralaVMontgomeryRJThe synergistic effect of autograft and BMP-7 in the treatment of atrophic nonunionsClin Orthop Relat Res2009467123239324819396502
  • Moghaddam-AlvandiAZimmermannGBuchlerAErgebnisse der Pseudarthrosenbehandlung mit “bone morphogenetic protein 7” (BMP-7) [Results of nonunion treatment with bone morphogenetic protein 7 (BMP-7)]Unfallchirurg20121156518526 German22476375
  • DaiJLiLJiangCWangCChenHChaiYBone morphogenetic protein for the healing of tibial fracture: a meta-analysis of randomized controlled trialsPLoS One20151010e014167026509264
  • LeeKBTaghaviCEMurraySSSongKJKeorochanaGWangJCBMP induced inflammation: a comparison of rhBMP-7 and rhBMP-2J Orthop Res201230121985199422674456
  • PhillipsAMOverview of the fracture healing cascadeInjury200536suppl 3S5S716188551
  • PapeHCMarcucioRHumphreyCColnotCKnobeMHarveyEJTrauma-induced inflammation and fracture healingJ Orthop Trauma201024952252520736786
  • CroesMOnerFCKruytMCProinflammatory mediators enhance the osteogenesis of human mesenchymal stem cells after lineage commitmentPLoS One2015107e013278126176237
  • KonTChoTJAizawaTExpression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healingJ Bone Miner Res20011661004101411393777
  • StreetJBaoMdeGuzmanLVascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnoverProc Natl Acad Sci U S A200299159656966112118119
  • MoghaddamAMullerURothHJWentzensenAGrutznerPAZimmermannGTRACP 5b and CTX as osteological markers of delayed fracture healingInjury201142875876421168135
  • WesthauserFZimmermannGMoghaddamSReaming in treatment of non-unions in long bones: cytokine expression course as a tool for evaluation of non-union therapyArch Orthop Trauma Surg201513581107111626085339
  • BenderDHaubruckPBoxrikerSKorffSSchmidmaierGMoghaddamAValidity of subjective smoking status in orthopedic patientsTher Clin Risk Manag2015111297130326345646
  • ZimmermannGWagnerCSchmeckenbecherKWentzensenAMoghaddamATreatment of tibial shaft non-unions: bone morphogenetic proteins versus autologous bone graftInjury200940suppl 3S50S5320082792
  • KanczlerJMOreffoROOsteogenesis and angiogenesis: the potential for engineering boneEur Cell Mater20081510011418454418
  • LuCMarcucioRMiclauTAssessing angiogenesis during fracture healingIowa Orthop J200626172616789443
  • HausmanMRSchafflerMBMajeskaRJPrevention of fracture healing in rats by an inhibitor of angiogenesisBone200129656056411728927
  • StreetJBaoMdeGuzmanLVascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnoverProc Natl Acad Sci U S A200299159656966112118119
  • BeamerBHettrichCLaneJVascular endothelial growth factor: an essential component of angiogenesis and fracture healingHSS J201061859419763695
  • SarahrudiKThomasABraunsteinerTWolfHVecseiVAharinejadSVEGF serum concentrations in patients with long bone fractures: a comparison between impaired and normal fracture healingJ Orthop Res200927101293129719402151
  • YoungSPatelZSKretlowJDDose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect modelTissue Eng Part A20091592347236219249918
  • OgilvieCMLuCMarcucioRVascular endothelial growth factor improves bone repair in a murine nonunion modelIowa Orthop J201232909423576927
  • EckardtHDingMLindMHansenESChristensenKSHvidIRecombinant human vascular endothelial growth factor enhances bone healing in an experimental nonunion modelJ Bone Joint Surg Br200587101434143816189323
  • TarkkaTSipolaAJamsaTAdenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissuesJ Gene Med20035756056612825195
  • RamoshebiLNRipamontiUOsteogenic protein-1, a bone morphogenetic protein, induces angiogenesis in the chick chorioallantoic membrane and synergizes with basic fibroblast growth factor and transforming growth factor-beta1Anat Rec200025919710710760748
  • LangenfeldEMLangenfeldJBone morphogenetic protein-2 stimulates angiogenesis in developing tumorsMol Cancer Res20042314114915037653
  • SuzukiYMontagneKNishiharaAWatabeTMiyazonoKBMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signallingJ Biochem2008143219920618006519
  • AkiyamaIYoshinoOOsugaYBone morphogenetic protein 7 increased vascular endothelial growth factor (VEGF)-a expression in human granulosa cells and VEGF receptor expression in endothelial cellsReprod Sci201421447748224023033
  • RegaGKaunCDemyanetsSVascular endothelial growth factor is induced by the inflammatory cytokines interleukin-6 and oncostatin m in human adipose tissue in vitro and in murine adipose tissue in vivoArterioscler Thromb Vasc Biol20072771587159517525365
  • CohenTNahariDCeremLWNeufeldGLeviBZInterleukin 6 induces the expression of vascular endothelial growth factorJ Biol Chem199627127367418557680
  • HeidemannJOgawaHDwinellMBAngiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2J Biol Chem2003278108508851512496258
  • JohnsonKEWilgusTAVascular endothelial growth factor and angiogenesis in the regulation of cutaneous wound repairAdv Wound Care (New Rochelle)201431064766125302139
  • GruysEToussaintMJMNiewoldTAKoopmansSJAcute phase reaction and acute phase proteinsJ Zhejiang Univ Sci B20056111045105616252337
  • MountziarisPMMikosAGModulation of the inflammatory response for enhanced bone tissue regenerationTissue Eng Part B Rev200814217918618544015
  • LeeKBTaghaviCESongKJInflammatory characteristics of rhBMP-2 in vitro and in an in vivo rodent modelSpine2011363E149E15421242879
  • MaurerTZimmermannGMaurerSStegmaierSWagnerCHanschGMInhibition of osteoclast generation: a novel function of the bone morphogenetic protein 7/osteogenic protein 1Mediators Inflamm2012201217120923132958
  • RobinBNChaputCDZeitouniSRahmMDZerrisVASampsonHWCytokine-mediated inflammatory reaction following posterior cervical decompression and fusion associated with recombinant human bone morphogenetic protein-2: a case studySpine20103523E1350E135420938385
  • BastianOPillayJAlblasJLeenenLKoendermanLBlokhuisTSystemic inflammation and fracture healingJ Leukoc Biol201189566967321208896
  • CampbellDJKimCHButcherECChemokines in the systemic organization of immunityImmunol Rev2003195587112969310
  • KolarPGaberTPerkaCDudaGNButtgereitFHuman early fracture hematoma is characterized by inflammation and hypoxiaClin Orthop Relat Res2011469113118312621409457
  • RundleCHWangHYuHMicroarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repairBone200638452152916321582
  • GerstenfeldLCCullinaneDMBarnesGLGravesDTEinhornTAFracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulationJ Cell Biochem200388587388412616527
  • KudoOSabokbarAPocockAItonagaIFujikawaYAthanasouNAInterleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanismBone20033211712584029
  • HeymannDRousselleAVgp130 Cytokine family and bone cellsCytokine200012101455146811023660
  • YangXRicciardiBFHernandez-SoriaAShiYPleshko CamachoNBostromMPCallus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout miceBone200741692893617921078
  • LocksleyRMKilleenNLenardoMJThe TNF and TNF receptor super-families: integrating mammalian biologyCell2001104448750111239407
  • BalgaRWetterwaldAPortenierJDolderSMuellerCHofstetterWTumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitroBone200639232533516580896
  • HaradaASekidoNAkahoshiTWadaTMukaidaNMatsushimaKEssential involvement of interleukin-8 (IL-8) in acute inflammationJ Leukoc Biol19945655595647964163
  • FullerKOwensJMChambersTJMacrophage inflammatory protein-1 alpha and IL-8 stimulate the motility but suppress the resorption of isolated rat osteoclastsJ Immunol199515411606560727751648
  • BendreMSMontagueDCPeeryTAkelNSGaddyDSuvaLJInterleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone diseaseBone2003331283712919697
  • DeForgeLEPrestonAMTakeuchiEKenneyJBoxerLARemickDGRegulation of interleukin 8 gene expression by oxidant stressJ Biol Chem19932683425568255768244994
  • VallierHACuretonBAPattersonBMRandomized, prospective comparison of plate versus intramedullary nail fixation for distal tibia shaft fracturesJ Orthop Trauma2011251273674121904230
  • MoghaddamAChildCBrucknerTGernerHJDanielVBiglariBPosttraumatic inflammation as a key to neuroregeneration after traumatic spinal cord injuryInt J Mol Sci20151647900791625860946