References
- NeuJWalkerWANecrotizing enterocolitisN Engl J Med2011364325526421247316
- RoweMIReblockKKKurkchubascheAGHealeyPJNecrotizing enterocolitis in the extremely low birth weight infantJ Pediatr Surg1994298987990 discussion 990–9817965535
- PatelRMKandeferSWalshMCEunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research NetworkCauses and timing of death in extremely premature infants from 2000 through 2011N Engl J Med2015372433134025607427
- SrinivasanPSBrandlerMDD’SouzaANecrotizing enterocolitisClin Perinatol2008351251272x18280885
- FrostBLJillingTCaplanMSThe importance of pro-inflammatory signaling in neonatal NECSemin Perinatol200832210010618346533
- CaplanMSSimonDJillingTThe role of PAF, TLR, and the inflammatory response in neonatal necrotizing enterocolitisSemin Pediatr Surg200514314515116084401
- SodhiCPShiXHRichardsonWMToll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitisGastroenterology2010138118519619786028
- EganCESodhiCPGoodMToll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitisJ Clin Invest2016126249550826690704
- LeaphartCLCavalloJGribarSCA critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repairJ Immunol200717974808482017878380
- NealMDJiaHEyerBDiscovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitorsPLoS One201386e6577923776545
- GoodMSiggersRHSodhiCPAmniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epitheliumProc Natl Acad Sci U S A201210928113301133522733781
- JurenkaJSAnti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical researchAltern Med Rev200914214115319594223
- GoelAKunnumakkaraABAggarwalBBCurcumin as “Curecumin”: from kitchen to clinicBiochem Pharmacol200875478780917900536
- BasnetPSkalko-BasnetNCurcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatmentMolecules2011166456721642934
- ZhongKCurcumin mediates a protective effect via TLR-4/NF-κB signaling pathway in rat model of severe acute pancreatitisCell Biochem Biophys201573117518025711190
- JiaSHWeiHYuJLWeiXDZhangXPLiJCProtective effects of curcumin on neonatal rats with necrotizing enterocolitisZhongguo Dang Dai Er Ke Za Zhi [Chin J Contemp Pediatr]2010122132136
- SalhBAssiKTemplemanVCurcumin attenuates DNB-induced murine colitisAm J Physiol Gastrointest Liver Physiol20032851G235G24312637253
- ZhangXWuJYeBWangQXieXShenHProtective effect of curcumin on TNBS-induced intestinal inflammation is mediated through the JAK/STAT pathwayBMC Complement Altern Med201616129927544348
- AliTShakirFMortonJCurcumin and inflammatory bowel disease: biological mechanisms and clinical implicationDigestion201285424925522950087
- LubbadAOriowoMAKhanICurcumin attenuates inflammation through inhibition of TLR-4 receptor in experimental colitisMol Cell Biochem20093221–212713519002562
- LiuYFuchsJLiCLinJIL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-induced STAT3 phosphorylation in human hepatocellular cancer cellsCell Cycle20109173423342720818158
- BillMANicholasCMaceTAStructurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell linesPLoS One201278e4072422899991
- IkenouchiJFuruseMFuruseKSasakiHTsukitaSTsukitaSTricellulin constitutes a novel barrier at tricellular contacts of epithelial cellsJ Cell Biol2005171693994516365161
- SuzukiTYoshinagaNTanabeSInterleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epitheliumJ Biol Chem201128636312633127121771795
- ZhangCShermanMPPrinceLSPaneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature miceDis Model Mech20125452253222328592
- MusemecheCCaplanMHsuehWSunXKellyAExperimental necrotizing enterocolitis: the role of polymorphonuclear neutrophilsJ Pediatr Surg199126910471049 discussion 1049–10501941482
- CaniPDBibiloniRKnaufCChanges in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in miceDiabetes20085761470148118305141
- GuptaJNebredaARAnalysis of intestinal permeability in miceBio-protocol2014422e1289
- HackamDJGoodMSodhiCPMechanisms of gut barrier failure in the pathogenesis of necrotizing enterocolitis: Toll-like receptors throw the switchSemin Pediatr Surg2013222768223611610
- LiuYFathereeNYMangalatNRhoadsJMLactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestineAm J Physiol Gastrointest Liver Physiol20123026G608G61722207578
- HalpernMDDenningPWThe role of intestinal epithelial barrier function in the development of NECTissue Barriers201531–2e100070725927016
- ClaudECWalkerWABacterial colonization, probiotics, and necrotizing enterocolitisJ Clin Gastroenterol200842suppl 2S46S5218520617
- HullMAFisherJGGutierrezIMMortality and management of surgical necrotizing enterocolitis in very low birth weight neonates: a prospective cohort studyJ Am Coll Surg201421861148115524468227
- JillingTSimonDLuJThe roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitisJ Immunol200617753273328216920968
- LuPSodhiCPHackamDJToll-like receptor regulation of intestinal development and inflammation in the pathogenesis of necrotizing enterocolitisPathophysiology2014211819324365655
- ClaudECWalkerWAHypothesis: inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitisFASEB J20011581398140311387237
- LinPWNasrTRStollBJNecrotizing enterocolitis: recent scientific advances in pathophysiology and preventionSemin Perinatol2008322708218346530
- BillMAFuchsJRLiCThe small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activityMol Cancer2010916520576164
- FosseySLBearMDLinJThe novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell linesBMC Cancer20111111221443800
- SolimanAMichelsenKSKarahashiHPlatelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitisPLoS One2010510e1504420976181
- EckertJScottBLawrenceSMFLLL32, a curcumin analog, ameliorates intestinal injury in necrotizing enterocolitisPoster presented at: Pediatric Academic Society MeetingApril 28, 2015San Diego, CA, USA