Possible Role of Regulatory B Cells in Different Behçet’s Disease Phenotypes and Therapies: First Report from Egypt

References

• Yilmaz S, Simsek I, Cinar M, et al. Patient-driven assessment of disease activity in Behcet’s syndrome: cross-cultural adaptation, reliability and validity of the Turkish version of the Behcet’s Syndrome Activity Score. Clin Exp Rheumatol. 2013;31(3 Suppl 77):77–83.
   PubMed Web of Science ®Google Scholar
• Kural-Seyahi E, Fresko I, Seyahi N, et al. The long-term mortality and morbidity of Behcet syndrome: a 2-decade outcome survey of 387 patients followed at a dedicated center. Medicine (Baltimore). 2003;82(1):60–76. doi:10.1097/00005792-200301000-00006
   PubMed Web of Science ®Google Scholar
• Galeone M, Colucci R, D’Erme AM, Moretti S, Lotti T. Potential Infectious Etiology of Behcet’s Disease. Patholog Res Int. 2012;2012:595380. doi:10.1155/2012/595380
   PubMedGoogle Scholar
• Kaneko S, Suzuki N, Yamashita N, et al. Characterization of T cells specific for an epitope of human 60-kD heat shock protein (hsp) in patients with Behcet’s disease (BD) in Japan. Clin Exp Immunol. 1997;108(2):204–212. doi:10.1046/j.1365-2249.1997.3611265.x
   PubMed Web of Science ®Google Scholar
• Direskeneli H. Innate and adaptive responses to heat shock proteins in Behcet’s Disease. Genet Res Int. 2013;2013:249157. doi:10.1155/2013/249157
   PubMedGoogle Scholar
• de Menthon M, Lavalley MP, Maldini C, Guillevin L. Mahr A. HLA-B51/B5 and the risk of Behcet’s disease: a systematic review and meta-analysis of case-control genetic association studies. Arthritis Rheum. 2009;61(10):1287–1296. doi:10.1002/art.24642
   PubMed Web of Science ®Google Scholar
• Kirino Y, Bertsias G, Ishigatsubo Y, et al. Genome-wide association analysis identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1. Nat Genet. 2013;45(2):202–207. doi:10.1038/ng.2520
   PubMed Web of Science ®Google Scholar
• Hasan MS, Bergmeier LA, Petrushkin H, Fortune F. Gamma Delta (gammadelta) T cells and their involvement in Behcet’s Disease. J Immunol Res. 2015;2015:705831. doi:10.1155/2015/705831
   PubMed Web of Science ®Google Scholar
• Puccetti A, Fiore PF, Pelosi A, et al. Gene expression profiling in Behcet’s Disease Indicates an autoimmune component in the pathogenesis of the disease and opens new avenues for targeted therapy. J Immunol Res. 2018;2018:4246965. doi:10.1155/2018/4246965
   PubMed Web of Science ®Google Scholar
• Eksioglu-Demiralp E, Kibaroglu A, Direskeneli H, et al. Phenotypic characteristics of B cells in Behcet’s disease: increased activity in B cell subsets. J Rheumatol. 1999;26(4):826–832.
   PubMed Web of Science ®Google Scholar
• Suzuki N, Sakane T, Ueda Y, Tsunematsu T. Abnormal B cell function in patients with Behcet’s disease. Arthritis Rheum. 1986;29(2):212–219. doi:10.1002/art.1780290209
   PubMed Web of Science ®Google Scholar
• van der Houwen TB, van Hagen PM, Timmermans WM, et al. Chronic signs of memory B cell activation in patients with Behcet’s disease are partially restored by anti-tumour necrosis factor treatment. Rheumatology (Oxford). 2017;56(1):134–144. doi:10.1093/rheumatology/kew366
   PubMed Web of Science ®Google Scholar
• Davatchi F, Shams H, Rezaipoor M, et al. Rituximab in intractable ocular lesions of Behcet’s disease; randomized single-blind control study (pilot study). Int J Rheum Dis. 2010;13(3):246–252. doi:10.1111/j.1756-185X.2010.01546.x
   PubMed Web of Science ®Google Scholar
• Edwards J, Cambridge G, Abrahams V. Do self-perpetuating B lymphocytes drive human autoimmune disease? Immunology. 1999;97(2):188. doi:10.1046/j.1365-2567.1999.00772.x
   PubMed Web of Science ®Google Scholar
• Shimomura Y, Mizoguchi E, Sugimoto K, et al. Regulatory role of B-1 B cells in chronic colitis. Int Immunol. 2008;20(6):729–737. doi:10.1093/intimm/dxn031
   PubMed Web of Science ®Google Scholar
• Abdelwahab FA, Hassanein KM, Hetta HF, Abdelmalek MO, Zahran AM, El-Badawy O. Impact of deranged B cell subsets distribution in the development of HCV-related cirrhosis and HCC in type two diabetes mellitus. Sci Rep. 2020;10(1):1–11. doi:10.1038/s41598-020-77416-0
   PubMed Web of Science ®Google Scholar
• Hetta HF, Mekky MA, Zahran AM, et al. Regulatory B cells and their cytokine profile in HCV-related hepatocellular carcinoma: association with regulatory T cells and disease progression. Vaccines. 2020;8(3):380. doi:10.3390/vaccines8030380
   Web of Science ®Google Scholar
• Hetta HF, Mwafey IM, Batiha GE-S, et al. Cd19+ cd24hi cd38hi regulatory b cells and memory b cells in periodontitis: association with pro-inflammatory and anti-inflammatory cytokines. Vaccines. 2020;8(2):340. doi:10.3390/vaccines8020340
   Web of Science ®Google Scholar
• Hassanin KM, Bakr OH, Hetta HF, Mohammed F. B (REG) CELLS IN HEPATITIS C VIRUS AND DIABETES. Bull Pharmaceutical Sci Assiut. 2019;42(1):9–18. doi:10.21608/bfsa.2019.62254
   Google Scholar
• Hetta H, Elkady A, Tohamy T, Badary M. Regulatory B cells: key players in hepatocellular carcinoma progression. Gastroenterol Hepatol Open Access. 2016;5(2):00136. doi:10.15406/ghoa.2016.05.00136
   Google Scholar
• Yoon JY, Lee Y, Yu SL, et al. Aberrant expression of interleukin-10 and activation-induced cytidine deaminase in B cells from patients with Behcet’s disease. Biomed Rep. 2017;7(6):520–526. doi:10.3892/br.2017.996
   PubMedGoogle Scholar
• International Team for the Revision of the International Criteria for Behcet’s D. The International Criteria for Behcet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol. 2014;28(3):338–347. doi:10.1111/jdv.12107
   PubMed Web of Science ®Google Scholar
• Bhakta BB, Brennan P, James TE, Chamberlain MA, Noble BA, Silman AJ. Behcet’s disease: evaluation of a new instrument to measure clinical activity. Rheumatology (Oxford). 1999;38(8):728–733. doi:10.1093/rheumatology/38.8.728
   PubMed Web of Science ®Google Scholar
• International Society for Behçet’s Disease. Behçet’s Disease Current Activity Form 2006. Leeds: University of Leeds; 2006.
   Google Scholar
• Rhoden EL, Teloken C, Sogari PR, Vargas Souto CA. The use of the simplified International Index of Erectile Function (IIEF-5) as a diagnostic tool to study the prevalence of erectile dysfunction. Int J Impot Res. 2002;14(4):245–250. doi:10.1038/sj.ijir.3900859
   PubMed Web of Science ®Google Scholar
• Garcia-Batista ZE, Guerra-Pena K, Cano-Vindel A, Herrera-Martinez SX, Medrano LA. Validity and reliability of the Beck Depression Inventory (BDI-II) in general and hospital population of Dominican Republic. PLoS One. 2018;13(6):e0199750. doi:10.1371/journal.pone.0199750
   PubMed Web of Science ®Google Scholar
• Ray A, Dittel BN. Mechanisms of regulatory B cell function in autoimmune and inflammatory diseases beyond IL-10. J Clin Med. 2017;6:1. doi:10.3390/jcm6010012
   Web of Science ®Google Scholar
• Hirohata S, Kikuchi H. Histopathology of the ruptured pulmonary artery aneurysm in a patient with Behcet’s disease. Clin Exp Rheumatol. 2009;27(2 Suppl 53):S91–95.
   PubMed Web of Science ®Google Scholar
• Liu S, Ren J, Xia Q, et al. Preliminary case-control study to evaluate diagnostic values of C-reactive protein and erythrocyte sedimentation rate in differentiating active Crohn’s disease from intestinal lymphoma, intestinal tuberculosis and Behcet’s syndrome. Am J Med Sci. 2013;346(6):467–472. doi:10.1097/MAJ.0b013e3182959a18
   PubMed Web of Science ®Google Scholar
• Muftuoglu AU, Yazici H, Yurdakul S, et al. Behcet’s disease. Relation of serum C-reactive protein and erythrocyte sedimentation rates to disease activity. Int J Dermatol. 1986;25(4):235–239. doi:10.1111/j.1365-4362.1986.tb02232.x
   PubMed Web of Science ®Google Scholar
• Frey MK, Winter M-P, Alimohammadi A, et al. Resolution of venous thrombus is depending on B-lymphocytes. Eur Respir J. 2012;40(Suppl 56):P3909.
   Google Scholar
• Luther N, Shahneh F, Brahler M, et al. Innate Effector-Memory T-cell activation regulates post-thrombotic vein wall inflammation and thrombus resolution. Circ Res. 2016;119(12):1286–1295. doi:10.1161/CIRCRESAHA.116.309301
   PubMed Web of Science ®Google Scholar
• Mathian A, Jouenne R, Chader D, et al. Regulatory T cell responses to high-dose methylprednisolone in active systemic lupus erythematosus. PLoS One. 2015;10(12):e0143689. doi:10.1371/journal.pone.0143689
   PubMed Web of Science ®Google Scholar
• Braitch M, Harikrishnan S, Robins RA, et al. Glucocorticoids increase CD4CD25 cell percentage and Foxp3 expression in patients with multiple sclerosis. Acta Neurol Scand. 2009;119(4):239–245. doi:10.1111/j.1600-0404.2008.01090.x
   PubMed Web of Science ®Google Scholar
• Cepika AM, Marinic I, Morovic-Vergles J, Soldo-Juresa D, Gagro A. Effect of steroids on the frequency of regulatory T cells and expression of FOXP3 in a patient with systemic lupus erythematosus: a two-year follow-up. Lupus. 2007;16(5):374–377. doi:10.1177/0961203307077990
   PubMed Web of Science ®Google Scholar