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Original Research

White Blood Cell Count as a Predictor of Incident Type 2 Diabetes Mellitus Among Non-Obese Adults: A Longitudinal 10-Year Analysis of the Korean Genome and Epidemiology Study

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Pages 1235-1242 | Published online: 01 Apr 2021

References

  • Chatterjee S, Khunti K, Davies MJ. Type 2 diabetes. Lancet. 2017;389(10085):2239–2251. doi:10.1016/s0140-6736(17)30058-2
  • Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of Type 2 diabetes – global burden of disease and forecasted trends. J Epidemiol Glob Health. 2020;10(1):107–111. doi:10.2991/jegh.k.191028.001
  • Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018;14(2):88–98. doi:10.1038/nrendo.2017.151
  • American Diabetes Association. Economic costs of diabetes in the U.S. in 2017. Diabetes Care. 2018;41(5):917–928. doi:10.2337/dci18-0007
  • Global report on diabetes [homepage on the internet]. Geneva: World Health Organization; 2016. Available from: https://apps.who.int/iris/bitstream/handle/10665/204871/9789241565257_eng;jsessionid=BF5106442C6C33727D424A2C64F767AA?sequence=1. Accessed January 6, 2021.
  • Saeedi P, Petersohn I, Salpea P, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. Diabetes Res Clin Pract. 2019;157:107843. doi:10.1016/j.diabres.2019.107843
  • Kim BY, Won JC, Lee JH, et al. Diabetes fact sheets in Korea, 2018: an appraisal of current status. Diabetes Metab J. 2019;43(4):487–494. doi:10.4093/dmj.2019.0067
  • Ha KH, Kim DJ. Trends in the diabetes epidemic in Korea. Endocrinol Metab (Seoul). 2015;30(2):142–146. doi:10.3803/EnM.2015.30.2.142
  • Vital Statistics Division, Statistics Korea, Shin H-Y, Kim J, et al. Cause-of-death statistics in 2018 in the Republic of Korea. J Korean Med Assoc. 2020;63(5):286–297. doi:10.5124/jkma.2020.63.5.286
  • Ma RC, Chan JC. Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States. Ann N Y Acad Sci. 2013;1281(1):64–91. doi:10.1111/nyas.12098
  • Huxley R, James WP, Barzi F, et al. Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertension. Obes Rev. 2008;9(Suppl 1):53–61. doi:10.1111/j.1467-789X.2007.00439.x
  • Ramachandran A, Ma RC, Snehalatha C. Diabetes in Asia. Lancet. 2010;375(9712):408–418. doi:10.1016/s0140-6736(09)60937-5
  • Kang HT, Shim JY, Lee HR, Park BJ, Linton JA, Lee YJ. Trends in prevalence of overweight and obesity in Korean adults, 1998–2009: the Korean National Health and Nutrition Examination Survey. J Epidemiol. 2014;24(2):109–116. doi:10.2188/jea.je20130017
  • Kim S, Subramanian SV, Oh J, Razak F. Trends in the distribution of body mass index and waist circumference among South Korean adults, 1998–2014. Eur J Clin Nutr. 2018;72(2):198–206. doi:10.1038/s41430-017-0024-7
  • Bae JC. Trends of diabetes epidemic in Korea. Diabetes Metab J. 2018;42(5):377–379. doi:10.4093/dmj.2018.0194
  • Esser N, Legrand-Poels S, Piette J, Scheen AJ, Paquot N. Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Res Clin Pract. 2014;105(2):141–150. doi:10.1016/j.diabres.2014.04.006
  • Calle MC, Fernandez ML. Inflammation and type 2 diabetes. Diabetes Metab. 2012;38(3):183–191. doi:10.1016/j.diabet.2011.11.006
  • Park JM, Lee DC, Lee YJ. Relationship between high white blood cell count and insulin resistance (HOMA-IR) in Korean children and adolescents: Korean National Health and Nutrition Examination Survey 2008–2010. Nutr Metab Cardiovasc Dis. 2017;27(5):456–461. doi:10.1016/j.numecd.2017.03.002
  • Mirza S, Hossain M, Mathews C, et al. Type 2-diabetes is associated with elevated levels of TNF-alpha, IL-6 and adiponectin and low levels of leptin in a population of Mexican Americans: a cross-sectional study. Cytokine. 2012;57(1):136–142. doi:10.1016/j.cyto.2011.09.029
  • Elimam H, Abdulla AM, Taha IM. Inflammatory markers and control of type 2 diabetes mellitus. Diabetes Metab Syndr. 2019;13(1):800–804. doi:10.1016/j.dsx.2018.11.061
  • Twig G, Afek A, Shamiss A, et al. White blood cells count and incidence of type 2 diabetes in young men. Diabetes Care. 2013;36(2):276–282. doi:10.2337/dc11-2298
  • Zhang H, Yang Z, Zhang W, et al. White blood cell subtypes and risk of type 2 diabetes. J Diabetes Complications. 2017;31(1):31–37. doi:10.1016/j.jdiacomp.2016.10.029
  • Vatcheva KP, Fisher-Hoch SP, Rahbar MH, Lee M, Olvera RL, McCormick JB. Association of total and differential white blood cells to development of type 2 diabetes in Mexican Americans in Cameron County hispanic cohort. Diabetes Res. 2015;1(4):103–112. doi:10.17140/droj-1-117
  • Nakanishi N, Yoshida H, Matsuo Y, Suzuki K, Tatara K. White blood-cell count and the risk of impaired fasting glucose or Type II diabetes in middle-aged Japanese men. Diabetologia. 2002;45(1):42–48. doi:10.1007/s125-002-8243-1
  • Gu Y, Hu K, Huang Y, et al. White blood cells count as an indicator to identify whether obesity leads to increased risk of type 2 diabetes. Diabetes Res Clin Pract. 2018;141:140–147. doi:10.1016/j.diabres.2018.04.041
  • Kim Y, Han BG, KoGES group. Cohort profile: the Korean Genome and Epidemiology Study (KoGES) consortium. Int J Epidemiol. 2017;46(2):e20. doi:10.1093/ije/dyv316
  • World Health Organization. Regional office for the Western Pacific. The Asia-Pacific perspective: redefining obesity and its treatment [homepage on the internet]. Sydney: Health Communications Australia; 2000. Available from: https://apps.who.int/iris/handle/10665/206936. Accessed January 6, 2021.
  • American Diabetes Association. Standards of medical care in diabetes—2018 abridged for primary care providers. Clin Diabetes. 2018;36(1):14–37. doi:10.2337/cd17-0119
  • van Greevenbroek MM, Schalkwijk CG, Stehouwer CD. Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences. Neth J Med. 2013;71(4):174–187.
  • Johnson AR, Milner JJ, Makowski L. The inflammation highway: metabolism accelerates inflammatory traffic in obesity. Immunol Rev. 2012;249(1):218–238. doi:10.1111/j.1600-065X.2012.01151.x
  • Shu CJ, Benoist C, Mathis D. The immune system’s involvement in obesity-driven type 2 diabetes. Semin Immunol. 2012;24(6):436–442. doi:10.1016/j.smim.2012.12.001
  • Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 2012;15(5):635–645. doi:10.1016/j.cmet.2012.04.001
  • Dasu MR, Ramirez S, Isseroff RR. Toll-like receptors and diabetes: a therapeutic perspective. Clin Sci (Lond). 2012;122(5):203–214. doi:10.1042/cs20110357
  • Chawla A, Nguyen KD, Goh YP. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol. 2011;11(11):738–749. doi:10.1038/nri3071
  • Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006;116(7):1793–1801. doi:10.1172/jci29069
  • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112(12):1796–1808. doi:10.1172/jci19246
  • Esposito K, Nappo F, Giugliano F, et al. Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus. Am J Clin Nutr. 2003;78(6):1135–1140. doi:10.1093/ajcn/78.6.1135
  • Tsalamandris S, Antonopoulos AS, Oikonomou E, et al. The role of inflammation in diabetes: current concepts and future perspectives. Eur Cardiol. 2019;14(1):50–59. doi:10.15420/ecr.2018.33.1
  • Halban PA, Polonsky KS, Bowden DW, et al. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014;99(6):1983–1992. doi:10.1210/jc.2014-1425
  • Brooks-Worrell B, Palmer JP. Immunology in the clinic review series; focus on metabolic diseases: development of islet autoimmune disease in type 2 diabetes patients: potential sequelae of chronic inflammation. Clin Exp Immunol. 2012;167(1):40–46. doi:10.1111/j.1365-2249.2011.04501.x
  • Ahlqvist E, Ahluwalia TS, Groop L. Genetics of type 2 diabetes. Clin Chem. 2011;57(2):241–254. doi:10.1373/clinchem.2010.157016
  • Kamata K, Mizukami H, Inaba W, et al. Islet amyloid with macrophage migration correlates with augmented β-cell deficits in type 2 diabetic patients. Amyloid. 2014;21(3):191–201. doi:10.3109/13506129.2014.937857
  • Cavelti-Weder C, Babians-Brunner A, Keller C, et al. Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes Care. 2012;35(8):1654–1662. doi:10.2337/dc11-2219
  • Butcher MJ, Hallinger D, Garcia E, et al. Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes. Diabetologia. 2014;57(3):491–501. doi:10.1007/s00125-013-3116-5
  • Wen L, Duffy A. Factors influencing the gut microbiota, inflammation, and type 2 diabetes. J Nutr. 2017;147(7):1468s–1475s. doi:10.3945/jn.116.240754
  • Scheithauer TPM, Dallinga-Thie GM, de Vos WM, Nieuwdorp M, van Raalte DH. Causality of small and large intestinal microbiota in weight regulation and insulin resistance. Mol Metab. 2016;5(9):759–770. doi:10.1016/j.molmet.2016.06.002
  • Burcelin R. Gut microbiota and immune crosstalk in metabolic disease. Mol Metab. 2016;5(9):771–781. doi:10.1016/j.molmet.2016.05.016
  • Alvarez-Curto E, Milligan G. Metabolism meets immunity: the role of free fatty acid receptors in the immune system. Biochem Pharmacol. 2016;114:3–13. doi:10.1016/j.bcp.2016.03.017
  • Arora P, Moll JM, Andersen D, et al. Body fluid from the parasitic worm Ascaris suum inhibits broad-acting pro-inflammatory programs in dendritic cells. Immunology. 2020;159(3):322–334. doi:10.1111/imm.13151