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Original Research

Grape Seed Proanthocyanidin Extract Moderated Retinal Pigment Epithelium Cellular Senescence Through NAMPT/SIRT1/NLRP3 Pathway

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Pages 3129-3143 | Published online: 12 Jul 2021

References

  • Blasiak J. Senescence in the pathogenesis of age-related macular degeneration. Cell Mol Life Sci. 2020;77(5):789–805.
  • Corbelli E, Parravano M, Sacconi R, et al. Prevalence and phenotypes of age-related macular degeneration in eyes with high myopia. Invest Ophthalmol Vis Sci. 2019;60(5):1394–1402.
  • Hyttinen JMT, Viiri J, Kaarniranta K, Blasiak J. Mitochondrial quality control in AMD: does mitophagy play a pivotal role? Cell Mol Life Sci. 2018;75(16):2991–3008.
  • Ueda K, Kim HJ, Zhao J, Song Y, Dunaief JL, Sparrow JR. Iron promotes oxidative cell death caused by bisretinoids of retina. Proc Natl Acad Sci U S A. 2018;115(19):4963–4968.
  • Yang X, Zhao L, Campos MM, et al. CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. Elife. 2020;9:e55564.
  • Wolk A, Upadhyay M, Ali M, et al. The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration. Redox Biol. 2020;101681.
  • Amjad S, Nisar S, Bhat AA, et al. Role of NAD(+) in regulating cellular and metabolic signaling pathways. Mol Metab. 2021;49:101195.
  • Chini CCS, Zeidler JD, Kashyap S, Warner G, Chini EN. Evolving concepts in NAD(+) metabolism. Cell Metab. 2021.
  • Wang Y, Grenell A, Zhong F, et al. Metabolic signature of the aging eye in mice. Neurobiol Aging. 2018;71:223–233.
  • Liebmann JM, Cioffi GA. Nicking glaucoma with nicotinamide? N Engl J Med. 2017;376(21):2079–2081.
  • Mekala NK, Kurdys J, Depuydt MM, Vazquez EJ, Rosca MG. Apoptosis inducing factor deficiency causes retinal photoreceptor degeneration. The protective role of the redox compound methylene blue. Redox Biol. 2019;20:107–117.
  • Jadeja RN, Powell FL, Jones MA, et al. Loss of NAMPT in aging retinal pigment epithelium reduces NAD(+) availability and promotes cellular senescence. Aging (Albany NY). 2018;10(6):1306–1323.
  • Cao G, Zeng X, Liu J, et al. Change of serum metabolome and cecal microflora in broiler chickens supplemented with grape seed extracts. Front Immunol. 2020;11:610934.
  • Wang L, Huang W, Zhan J. Grape seed proanthocyanidins induce autophagy and modulate survivin in HepG2 cells and inhibit xenograft tumor growth in vivo. Nutrients. 2019;11:12.
  • Ahmad SR, Gokulakrishnan P, Giriprasad R, Yatoo MA. Fruit-based natural antioxidants in meat and meat products: a review. Crit Rev Food Sci Nutr. 2015;55(11):1503–1513.
  • Nie Y, Sturzenbaum SR. Proanthocyanidins of natural origin: molecular mechanisms and implications for lipid disorder and aging-associated diseases. Adv Nutr. 2019;10(3):464–478.
  • Barbe A, Mellouk N, Rame C, et al. A grape seed extract maternal dietary supplementation improves egg quality and reduces ovarian steroidogenesis without affecting fertility parameters in reproductive hens. PLoS One. 2020;15(5):e0233169.
  • Chen C, Zhong Y, Wang JJ, et al. Regulation of Nrf2 by X box-binding protein 1 in retinal pigment epithelium. Front Genet. 2018;9:658.
  • Zhu W, Wu Y, Meng YF, et al. Effect of curcumin on aging retinal pigment epithelial cells. Drug Des Devel Ther. 2015;9:5337–5344.
  • Lin H, Xu H, Liang FQ, et al. Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011;52(6):3521–3529.
  • O’Mealey GB, Berry WL, Plafker SM. Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission. Redox Biol. 2017;11:103–110.
  • Marie M, Forster V, Fouquet S, et al. Phototoxic damage to cone photoreceptors can be independent of the visual pigment: the porphyrin hypothesis. Cell Death Dis. 2020;11(8):711.
  • Braidy N, Liu Y. NAD+ therapy in age-related degenerative disorders: a benefit/risk analysis. Exp Gerontol. 2020;132:110831.
  • Wang S, Wang X, Cheng Y, et al. Autophagy dysfunction, cellular senescence, and abnormal immune-inflammatory responses in AMD: from mechanisms to therapeutic potential. Oxid Med Cell Longev. 2019;2019:3632169.
  • Miller JJ, Fink A, Banagis JA, et al. Sirtuin activation targets IDH-mutant tumors. Neuro Oncol. 2021;23(1):53–62.
  • Zhou Y, Wang S, Wan T, et al. Cyanidin-3-O-beta-glucoside inactivates NLRP3 inflammasome and alleviates alcoholic steatohepatitis via SirT1/NF-kappaB signaling pathway. Free Radic Biol Med. 2020.
  • Cai X, Bao L, Ren J, Li Y, Zhang Z. Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1alpha axis in vitro. Food Funct. 2016;7(2):805–815.
  • Pan S, Leng J, Deng X, et al. Nicotinamide increases the sensitivity of chronic myeloid leukemia cells to doxorubicin via the inhibition of SIRT1. J Cell Biochem. 2020;121(1):574–586.
  • Coryell PR, Diekman BO, Loeser RF. Mechanisms and therapeutic implications of cellular senescence in osteoarthritis. Nat Rev Rheumatol. 2021;17(1):47–57.
  • Dominic A, Banerjee P, Hamilton DJ, Le NT, Abe JI. Time-dependent replicative senescence vs. disturbed flow-induced pre-mature aging in atherosclerosis. Redox Biol. 2020;101614.
  • Guan Y, Zhang C, Lyu G, et al. Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts. Nucleic Acids Res. 2020;48(19):10909–10923.
  • Borghesan M, Hoogaars WMH, Varela-Eirin M, Talma N, Demaria M, Senescence-Centric A. View of aging: implications for longevity and disease. Trends Cell Biol. 2020.
  • Faber C, Juel HB, Jensen BAH, et al. Chemokine expression in murine RPE/Choroid in response to systemic viral infection and elevated levels of circulating interferon-gamma. Invest Ophthalmol Vis Sci. 2019;60(1):192–201.
  • Kaarniranta K, Pawlowska E, Szczepanska J, Blasiak J. DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA accumulation versus miRNA dysregulation. Aging Dis. 2020;11(4):851–862.
  • Vega R, Carretero M, Bonilla LL. Anomalous angiogenesis in retina. Biomedicines. 2021;9(2):224.
  • Oubaha M, Miloudi K, Dejda A, et al. Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy. Sci Transl Med. 2016;8(362):362ra144.
  • Kuo C, Green CR, Rupenthal ID, Mugisho OO. Connexin43 hemichannel block protects against retinal pigment epithelial cell barrier breakdown. Acta Diabetol. 2020;57(1):13–22.
  • Rao A, Strauss O, Kokkinou E, et al. Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs. Nat Commun. 2020;11(1):2049.
  • Korhonen E, Bisevac J, Hyttinen JMT, et al. UV-B-induced inflammasome activation can be prevented by cis-urocanic acid in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2020;61(4):7.
  • Du J, Wang Y, Tu Y, et al. A prodrug of epigallocatechin-3-gallate alleviates high glucose-induced pro-angiogenic factor production by inhibiting the ROS/TXNIP/NLRP3 inflammasome axis in retinal Muller cells. Exp Eye Res. 2020;196:108065.
  • Mat Nor MN, Rupenthal ID, Green CR, Acosta ML. Connexin hemichannel block using orally delivered tonabersat improves outcomes in animal models of retinal disease. Neurotherapeutics. 2020;17(1):371–387.
  • Han Y, Sun W, Ren D, et al. SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion. Redox Biol. 2020;34:101538.