Changes of Lipopolysaccharide-Induced Acute Kidney and Liver Injuries in Rats Based on Metabolomics Analysis

References

• Deng M, Scott MJ, Loughran P, et al. Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis. J Immunol. 2013;190(10):5152–5160. doi:10.4049/jimmunol.1300496
   PubMed Web of Science ®Google Scholar
• Calvano SE, Coyle SM. Experimental human endotoxemia: a model of the systemic inflammatory response syndrome? Surg Infect (Larchmt). 2012;13(5):293–299. doi:10.1089/sur.2012.155
   PubMed Web of Science ®Google Scholar
• Fong YM, Marano MA, Moldawer LL, et al. The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans. J Clin Invest. 1990;85(6):1896–1904. doi:10.1172/JCI114651
   PubMed Web of Science ®Google Scholar
• Khovidhunkit W, Kim MS, Memon RA, et al. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J Lipid Res. 2004;45(7):1169–1196.
   PubMed Web of Science ®Google Scholar
• Pearce EL, Pearce EJ. Metabolic pathways in immune cell activation and quiescence. Immunity. 2013;38(4):633–643. doi:10.1016/j.immuni.2013.04.005
   PubMed Web of Science ®Google Scholar
• Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, et al. Untargeted metabolomics strategies-challenges and emerging directions. J Am Soc Mass Spectrom. 2016;27(12):1897–1905. doi:10.1007/s13361-016-1469-y
   PubMed Web of Science ®Google Scholar
• Eckerle M, Ambroggio L, Puskarich M, et al. Metabolomics as a driver in advancing precision medicine in sepsis. Pharmacotherapy. 2017;37(9):1023–1032. doi:10.1002/phar.1974
   PubMed Web of Science ®Google Scholar
• Zhang H, Sha J, Feng X, et al. Dexmedetomidine ameliorates LPS induced acute lung injury via GSK-3β/STAT3-NF-κB signaling pathway in rats. Int Immunopharmacol. 2019;74:105717. doi:10.1016/j.intimp.2019.105717
   PubMed Web of Science ®Google Scholar
• Abdelmageed M, El-Awady M, Suddek G. Apocynin ameliorates endotoxin-induced acute lung injury in rats. Int Immunopharmacol. 2016;30:163–170. doi:10.1016/j.intimp.2015.12.006
   PubMed Web of Science ®Google Scholar
• Dunn WB, Broadhurst D, Begley P, et al. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat Protoc. 2011;6(7):1060–1083. doi:10.1038/nprot.2011.335
   PubMed Web of Science ®Google Scholar
• Zelena E, Dunn WB, Broadhurst D, et al. Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum. Anal Chem. 2009;81(4):1357–1364. doi:10.1021/ac8019366
   PubMed Web of Science ®Google Scholar
• Want EJ, Masson P, Michopoulos F, et al. Global metabolic profiling of animal and human tissues via UPLC-MS. Nat Protoc. 2013;8(1):17–32. doi:10.1038/nprot.2012.135
   PubMed Web of Science ®Google Scholar
• Liu M, Gong X, Quan Y, et al. A cell-based metabonomics approach to investigate the varied influences of chrysophanol-8-O-β-D-glucoside with different concentrations on L-02 cells. Front Pharmacol. 2018;9:1530. doi:10.3389/fphar.2018.01530
   PubMed Web of Science ®Google Scholar
• Thevenot EA, Roux A, Xu Y, et al. Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. J Proteome Res. 2015;14(8):3322–3335. doi:10.1021/acs.jproteome.5b00354
   PubMed Web of Science ®Google Scholar
• Huang X, Gan G, Wang X, et al. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15(7):1258–1279. doi:10.1080/15548627.2019.1580105
   PubMed Web of Science ®Google Scholar
• Kasawara KT, Cotechini T, Macdonald-Goodfellow SK, et al. Moderate exercise attenuates lipopolysaccharide-induced inflammation and associated maternal and fetal morbidities in pregnant rats. PLoS One. 2016;11(4):e0154405. doi:10.1371/journal.pone.0154405
   PubMed Web of Science ®Google Scholar
• Shan J, Qian W, Kang A, et al. Lipid profile perturbations in the plasma and lungs of mice with LPS-induced acute lung injury revealed by UHPLC-ESI-Q exactive HF MS analysis. J Pharm Biomed Anal. 2019;162:242–248. doi:10.1016/j.jpba.2018.09.037
   PubMed Web of Science ®Google Scholar
• Geng C, Guo Y, Wang C, et al. Comprehensive evaluation of lipopolysaccharide-induced changes in rats based on metabolomics. J Inflamm Res. 2020;13:477–486. doi:10.2147/JIR.S266012
   PubMed Web of Science ®Google Scholar
• Seán TA, Seán C, Paul NM, et al. Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse. Brain Behav Immun. 2015;43:98–109. doi:10.1016/j.bbi.2014.07.007
   PubMed Web of Science ®Google Scholar
• Zeki ÖC, Eylem CC, Reçber T, et al. Integration of GC-MS and LC-MS for untargeted metabolomics profiling. J Pharm Biomed Anal. 2020;190:113509. doi:10.1016/j.jpba.2020.113509
   PubMed Web of Science ®Google Scholar
• Ameer YT, Helene CB, Yewon C, et al. Dietary linoleic acid lowering reduces lipopolysaccharide-induced increase in brain arachidonic acid metabolism. Mol Neurobiol. 2017;54(6):4303–4315. doi:10.1007/s12035-016-9968-1
   PubMed Web of Science ®Google Scholar
• Liu YJ, Li H, Tian Y, et al. PCTR1 ameliorates lipopolysaccharide-induced acute inflammation and multiple organ damage via regulation of linoleic acid metabolism by promoting FADS1/FASDS2/ELOV2 expression and reducing PLA2 expression. Lab Invest. 2020;100(7):904–915. doi:10.1038/s41374-020-0412-9
   PubMed Web of Science ®Google Scholar
• Helioswilton SC, Patricía RS, Bethânea CP, da Silva JS, Cardoso CR. An overview of the modulatory effects of oleic acid in health and disease. Mini Rev Med Chem. 2013;13(2):201–210.
   PubMed Web of Science ®Google Scholar
• Zohreh S, Kashaf R, Daniel RK, et al. Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal? Curr Hypertens Rep. 2013;15(3):175–181. doi:10.1007/s11906-013-0344-5
   PubMed Web of Science ®Google Scholar
• Minjiang C, Siming L, Hong Z, et al. Identification of the potential metabolic pathways involved in the hepatic tumorigenesis of rat diethylnitrosamine-induced hepatocellular carcinoma via H NMR-based metabolomic analysis. Biomed Res Int. 2019;9367082.
   PubMed Web of Science ®Google Scholar
• Qu XY, Gao H, Sun JM, et al. Identification of key metabolites during cisplatin-induced acute kidney injury using an HPLC-TOF/MS-based non-targeted urine and kidney metabolomics approach in rats. Toxicology. 2020;431:152366. doi:10.1016/j.tox.2020.152366
   PubMed Web of Science ®Google Scholar
• Zhu Y, Li TT, Suzane RS, et al. A critical role of glutamine and asparagine γ-nitrogen in nucleotide biosynthesis in cancer cells hijacked by an oncogenic virus. MBio. 2017;8(4):e01179–17. doi:10.1128/mBio.01179-17
   PubMed Web of Science ®Google Scholar
• Zhang F, Wang XY, Pan LY, et al. Glutamine attenuates lipopolysaccharide-induced acute lung injury. Nutrition. 2009;25(6):692–698. doi:10.1016/j.nut.2008.11.032
   PubMed Web of Science ®Google Scholar
• Shrestha N, Chand L, Han M, et al. Glutamine inhibits CCl4 induced liver fibrosis in mice and TGF-β1 mediated epithelial-mesenchymal transition in mouse hepatocytes. Food Chem Toxicol. 2016;93:129–137. doi:10.1016/j.fct.2016.04.024
   PubMed Web of Science ®Google Scholar
• Zhan F, Wang X, Zhang J, et al. Glutamine alleviates the renal dysfunction associated with gentamicin-induced acute kidney injury in Sprague-Dawley rats. Biotechnol Appl Biochem. 2021;18.
   Google Scholar
• Gisele PO, Jamil ZK, Phillipe SLG, et al. Glutamine therapy reduces inflammation and extracellular trap release in experimental acute respiratory distress syndrome of pulmonary origin. Nutrients. 2019;11(4):831. doi:10.3390/nu11040831
   PubMed Web of Science ®Google Scholar
• Inas AA, Mariam Y, Laila R, Solieman A. Lipid peroxidation plasma biomarker correlated with hepatic fibrosis in human Schistosoma mansoni infection. Acta Parasitol. 2015;60(4):735–742. doi:10.1515/ap-2015-0105
   PubMed Web of Science ®Google Scholar
• Li R, Zhou XQ, Liu D, et al. Enhancing the activity and stability of Mn-superoxide dismutase by one-by-one ligation to catalase. Free Radic Biol Med. 2018;129:138–145. doi:10.1016/j.freeradbiomed.2018.09.018
   PubMed Web of Science ®Google Scholar
• Wu Q, Zhang H, Dong X, et al. UPLC-Q-TOF/MS based metabolomic profiling of serum and urine of hyperlipidemic rats induced by high fat diet. J Pharm Anal. 2014;4(6):360–367. doi:10.1016/j.jpha.2014.04.002
   PubMedGoogle Scholar
• Kayoko S, Chian JJ, Kyoko T, et al. Role of ROS production and turnover in the antioxidant activity of taurine. Adv Exp Med Biol. 2015;803:581–596.
   PubMed Web of Science ®Google Scholar
• Shao HB, Chu LY, Lu ZH, et al. Primary antioxidant free radical scavenging and redox signaling pathways in higher plant cells. Int J Biol Sci. 2007;4(1):8–14. doi:10.7150/ijbs.4.8
   PubMed Web of Science ®Google Scholar
• Schaffer SW, Jong CJ, Ramila KC, et al. Physiological roles of taurine in heart and muscle. J Biomed Sci. 2010;17(Suppl 1):S2. doi:10.1186/1423-0127-17-S1-S2
   PubMedGoogle Scholar
• Liu YY, Li F, Zhang L, et al. Taurine alleviates lipopolysaccharide‑induced liver injury by anti‑inflammation and antioxidants in rats. Mol Med Rep. 2017;16(5):6512–6517. doi:10.3892/mmr.2017.7414
   PubMed Web of Science ®Google Scholar
• Gordon FR, Ian LM. Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits. Pharmacol Ther. 2014;141(2):150–159. doi:10.1016/j.pharmthera.2013.09.006
   PubMed Web of Science ®Google Scholar
• Ping F, Guo Y, Cao YM, et al. Metabolomics analysis of the renal cortex in rats with acute kidney injury induced by sepsis. Front Mol Biosci. 2019;6:152. doi:10.3389/fmolb.2019.00152
   PubMed Web of Science ®Google Scholar
• Homma T, Fujii J. Application of glutathione as anti-oxidative and anti-aging drugs. Curr Drug Metab. 2015;16(7):560–571. doi:10.2174/1389200216666151015114515
   PubMed Web of Science ®Google Scholar
• Liao ST, Li P, Wang JS, et al. Protection of baicalin against lipopolysaccharide induced liver and kidney injuries based on H NMR metabolomic profiling. Toxicol Res. 2016;5(4):1148–1159. doi:10.1039/C6TX00082G
   Web of Science ®Google Scholar
• Shi C, Han X, Mao X, et al. Metabolic profiling of liver tissues in mice after instillation of fine particulate matter. Sci Total Environ. 2019;696:133974. doi:10.1016/j.scitotenv.2019.133974
   PubMed Web of Science ®Google Scholar
• José MFC, Manfred WB, Milton F, et al. Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism. Mol Cell Biol. 2002;22(13):4943–4951. doi:10.1128/MCB.22.13.4943-4951.2002
   PubMed Web of Science ®Google Scholar
• Saitoh W, Yamauchi S, Watanabe K, et al. Metabolomic analysis of arginine metabolism in acute hepatic injury in rats. J Toxicol Sci. 2014;39(1):41–50. doi:10.2131/jts.39.41
   PubMed Web of Science ®Google Scholar
• Yang CY, Hao RJ, Du XD, Wang Q, Deng Y, Sun R. Response to different dietary carbohydrate and protein levels of pearl oysters (Pinctada fucata martensii) as revealed by GC-TOF/MS-based metabolomics. Sci Total Environ. 2019;650:2614–2623. doi:10.1016/j.scitotenv.2018.10.023
   PubMed Web of Science ®Google Scholar
• Turner MC, Krewski D, Pope CA, et al. Long-term ambient fine particulate matter air pollution and lung cancer in a large cohort of never-smokers. Am J Respir Crit Care Med. 2011;184(12):1374–1381. doi:10.1164/rccm.201106-1011OC
   PubMed Web of Science ®Google Scholar