microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3

References

• Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006;440(7081):237–241. doi:10.1038/nature04516
   PubMed Web of Science ®Google Scholar
• Chen CJ, Shi Y, Hearn A, et al. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest. 2006;116(8):2262–2271. doi:10.1172/JCI28075
   PubMed Web of Science ®Google Scholar
• Qing YF, Zhang QB, Yang QB, Xie WG, Zhou JG. Altered expression of NLRP3 inflammasome in peripheral blood from gout patients might be associated with gouty arthritis. Gout Hyperuricemia. 2014;1(1):25–32.
   Google Scholar
• Qing YF, Zhang QB, Zhou JG, Jiang L. Changes in toll-like receptor (TLR)4-NFkappaB-IL1beta signaling in male gout patients might be involved in the pathogenesis of primary gouty arthritis. Rheumatol Int. 2014;34(2):213–220. doi:10.1007/s00296-013-2856-3
   PubMed Web of Science ®Google Scholar
• Kingsbury SR, Conaghan PG, McDermott MF. The role of the NLRP3 inflammasome in gout. J Inflamm Res. 2011;4:39–49. doi:10.2147/JIR.S11330
   PubMedGoogle Scholar
• Martin WJ, Harper JL. Innate inflammation and resolution in acute gout. Immunol Cell Biol. 2010;88(1):15–19. doi:10.1038/icb.2009.89
   PubMed Web of Science ®Google Scholar
• Ambros V. The functions of animal microRNAs. Nature. 2004;431(7006):350–355. doi:10.1038/nature02871
   PubMed Web of Science ®Google Scholar
• Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–297. doi:10.1016/S0092-8674(04)00045-5
   PubMed Web of Science ®Google Scholar
• He X, Jing Z, Cheng G. MicroRNAs: new regulators of toll-like receptor signalling pathways. Biomed Res Int. 2014;2014:945169. doi:10.1155/2014/945169
   PubMed Web of Science ®Google Scholar
• Haneklaus M, Gerlic M, O’Neill LA, Masters SL. miR-223: infection, inflammation and cancer. J Intern Med. 2013;274(3):215–226. doi:10.1111/joim.12099
   PubMed Web of Science ®Google Scholar
• Haneklaus M, Gerlic M, Kurowska-Stolarska M, et al. Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1beta production. J Immunol. 2012;189(8):3795–3799. doi:10.4049/jimmunol.1200312
   PubMed Web of Science ®Google Scholar
• Wang X, Chi J, Dong B, et al. MiR-223-3p and miR-22-3p inhibit monosodium urate-induced gouty inflammation by targeting NLRP3. Int J Rheum Dis. 2021;24(4):599–607. doi:10.1111/1756-185X.14089
   PubMed Web of Science ®Google Scholar
• Tian J, Zhou D, Xiang L, et al. MiR-223-3p inhibits inflammation and pyroptosis in monosodium urate-induced rats and fibroblast-like synoviocytes by targeting NLRP3. Clin Exp Immunol. 2021. doi:10.1111/cei.13587
   Web of Science ®Google Scholar
• Wallace SL, Robinson H, Masi AT, Decker JL, McCarty DJ, Yu TF. Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum. 1977;20(3):895–900. doi:10.1002/art.1780200320
   PubMed Web of Science ®Google Scholar
• Johnnidis JB, Harris MH, Wheeler RT, et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature. 2008;451(7182):1125–1129. doi:10.1038/nature06607
   PubMed Web of Science ®Google Scholar
• Getting SJ, Christian HC, Flower RJ, Perretti M. Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis Rheum. 2002;46(10):2765–2775. doi:10.1002/art.10526
   PubMed Web of Science ®Google Scholar
• Vyleta ML, Wong J, Magun BE. Suppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasome. PLoS One. 2012;7(5):e36044. doi:10.1371/journal.pone.0036044
   PubMed Web of Science ®Google Scholar
• Torres R, Macdonald L, Croll SD, et al. Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Ann Rheum Dis. 2009;68(10):1602–1608. doi:10.1136/ard.2009.109355
   PubMed Web of Science ®Google Scholar
• Ryckman C, McColl SR, Vandal K, et al. Role of S100A8 and S100A9 in neutrophil recruitment in response to monosodium urate monohydrate crystals in the air-pouch model of acute gouty arthritis. Arthritis Rheum. 2003;48(8):2310–2320. doi:10.1002/art.11079
   PubMedGoogle Scholar
• Jin HM, Kim T-J, Choi J-H, et al. MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis. Arthritis Res Ther. 2014;16(2):R88. doi:10.1186/ar4531
   PubMed Web of Science ®Google Scholar
• McGettrick AF, O’Neill LA. NLRP3 and IL-1beta in macrophages as critical regulators of metabolic diseases. Diabetes Obes Metab. 2013;15(Suppl 3):19–25. doi:10.1111/dom.12169
   PubMedGoogle Scholar
• Bauernfeind F, Rieger A, Schildberg FA, Knolle PA, Schmid-Burgk JL, Hornung V. NLRP3 inflammasome activity is negatively controlled by miR-223. J Immunol. 2012;189(8):4175–4181. doi:10.4049/jimmunol.1201516
   PubMed Web of Science ®Google Scholar
• Zhao G, Jiang K, Yang Y, et al. The potential therapeutic role of miR-223 in bovine endometritis by targeting the NLRP3 inflammasome. Front Immunol. 2018;9:1916. doi:10.3389/fimmu.2018.01916
   PubMed Web of Science ®Google Scholar
• Wang K, Long B, Liu F, et al. A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223. Eur Heart J. 2016;37(33):2602–2611. doi:10.1093/eurheartj/ehv713
   PubMed Web of Science ®Google Scholar
• Ray A, Dittel BN. Isolation of mouse peritoneal cavity cells. J Vis Exp. 2010;35.
   Google Scholar
• Zheng SC, Zhu XX, Xue Y, et al. Role of the NLRP3 inflammasome in the transient release of IL-1beta induced by monosodium urate crystals in human fibroblast-like synoviocytes. J Inflamm. 2015;12:30. doi:10.1186/s12950-015-0070-7
   Google Scholar
• Mankan AK, Dau T, Jenne D, Hornung V. The NLRP3/ASC/Caspase-1 axis regulates IL-1beta processing in neutrophils. Eur J Immunol. 2012;42(3):710–715. doi:10.1002/eji.201141921
   PubMed Web of Science ®Google Scholar
• Yang QB, He YL, Zhang QB, Mi QS, Zhou JG. Downregulation of transcription factor T-bet as a protective strategy in monosodium urate-induced gouty infLammation. Front Immunol. 2019;10:1199. doi:10.3389/fimmu.2019.01199
   PubMed Web of Science ®Google Scholar
• Perez-Ruiz F, Castillo E, Chinchilla SP, Herrero-Beites AM. Clinical manifestations and diagnosis of gout. Rheum Dis Clin North Am. 2014;40(2):193–206. doi:10.1016/j.rdc.2014.01.003
   PubMed Web of Science ®Google Scholar
• Amaral FA, Costa VV, Tavares LD, et al. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis Rheum. 2012;64(2):474–484. doi:10.1002/art.33355
   PubMed Web of Science ®Google Scholar
• Mitroulis I, Kambas K, Ritis K. Neutrophils, IL-1beta, and gout: is there a link? Semin Immunopathol. 2013;35(4):501–512. doi:10.1007/s00281-013-0361-0
   PubMed Web of Science ®Google Scholar
• Martin WJ, Walton M, Harper J. Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout. Arthritis Rheum. 2009;60(1):281–289. doi:10.1002/art.24185
   PubMed Web of Science ®Google Scholar
• Liu-Bryan R, Scott P, Sydlaske A, Rose DM, Terkeltaub R. Innate immunity conferred by toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum. 2005;52(9):2936–2946. doi:10.1002/art.21238
   PubMedGoogle Scholar
• Wang J, Bai X, Song Q, et al. miR-223 inhibits lipid deposition and inflammation by suppressing toll-like receptor 4 signaling in macrophages. Int J Mol Sci. 2015;16(10):24965–24982. doi:10.3390/ijms161024965
   PubMed Web of Science ®Google Scholar