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Original Research

Hydrogen Sulfide Contributes to Uterine Quiescence Through Inhibition of NLRP3 Inflammasome Activation by Suppressing the TLR4/NF-κB Signalling Pathway

, , , , , , , & show all
Pages 2753-2768 | Published online: 25 Jun 2021

References

  • Romero R, Xu Y, Plazyo O, et al. A Role for the Inflammasome in Spontaneous Labor at Term. Am J Reprod Immunol. 2018;79(6):e12440. doi:10.1111/aji.12440
  • Gomez-Lopez N, Romero R, Xu Y, et al. A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis. Reprod Sci. 2017;24(6):934–953. doi:10.1177/1933719116675058
  • Liu L, Oza S, Hogan D, et al. Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis. Lancet. 2015;385(9966):430–440. doi:10.1016/S0140-6736(14)61698-6
  • You S, Cui AM, Hashmi SF, et al. Dysregulation of bile acids increases the risk for preterm birth in pregnant women. Nat Commun. 2020;11(1):2111. doi:10.1038/s41467-020-15923-4
  • Vogel JP, Chawanpaiboon S, Moller AB, et al. The global epidemiology of preterm birth. Best Pract Res Clin Obstet Gynaecol. 2018:523. doi:10.1016/j.bpobgyn.2018.04.003
  • Frey HA, Klebanoff MA. The epidemiology, etiology, and costs of preterm birth. Semin Fetal Neonatal Med. 2016;21(2):68–73. doi:10.1016/j.siny.2015.12.011
  • Verschueren KJC, Prust ZD, Paidin RR, et al. Childbirth outcomes and ethnic disparities in Suriname: a nationwide registry-based study in a middle-income country. Reprod Health. 2020;17(1):62. doi:10.1186/s12978-020-0902-7
  • Goldenberg RL, Culhane JF, Iams JD, et al. Epidemiology and causes of preterm birth. Lancet. 2008;371(9606):75–84. doi:10.1016/S0140-6736(08)60074-4
  • Munoz-Perez VM, Ortiz MI, Carino-Cortes R, et al. Preterm Birth, Inflammation and Infection: new Alternative Strategies for their Prevention. Curr Pharm Biotechnol. 2019;20(5):354–365. doi:10.2174/1389201020666190408112013
  • Sivarajasingam SP, Imami N, Johnson MR. Myometrial cytokines and their role in the onset of labour. J Endocrinol. 2016;231(3):R101–R119. doi:10.1530/JOE-16-0157
  • Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol. 2010;11(5):373–384. doi:10.1038/ni.1863
  • Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature. 2004;430(6996):257–263. doi:10.1038/nature02761
  • Chen Z, Liu Q, Zhu Z, et al. Toll-like receptor 4 contributes to uterine activation by upregulating pro-inflammatory cytokine and CAP expression via the NF-kappaB/P38MAPK signaling pathway during pregnancy. J Cell Physiol. 2020;235(1):513–525. doi:10.1002/jcp.28991
  • Chen GY, Nunez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol. 2010;10(12):826–837. doi:10.1038/nri2873
  • Spel L, Martinon F. Inflammasomes contributing to inflammation in arthritis. Immunol Rev. 2020;294(1):48–62. doi:10.1111/imr.12839
  • Tong Y, Wang Z, Cai L, et al. NLRP3 Inflammasome and Its Central Role in the Cardiovascular Diseases. Oxid Med Cell Longev. 2020:20204293206. doi:10.1155/2020/4293206
  • Prochnicki T, Latz E. Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control. Cell Metab. 2017;26(1):71–93. doi:10.1016/j.cmet.2017.06.018
  • Youm YH, Grant RW, McCabe LR, et al. Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. Cell Metab. 2013;18(4):519–532. doi:10.1016/j.cmet.2013.09.010
  • Komada T, Usui F, Kawashima A, et al. Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury. Sci Rep. 2015:510901. doi:10.1038/srep10901
  • Kobayashi M, Usui-Kawanishi F, Karasawa T, et al. The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. PLoS One. 2017;12(5):e0176676. doi:10.1371/journal.pone.0176676
  • Neudecker V, Haneklaus M, Jensen O, et al. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J Exp Med. 2017;214(6):1737–1752. doi:10.1084/jem.20160462
  • Kim EH, Park MJ, Park S, et al. Increased expression of the NLRP3 inflammasome components in patients with Behcet’s disease. J Inflamm. 2015;12:1241. doi:10.1186/s12950-015-0086-z
  • Holwerda KM, Bos EM, Rajakumar A, et al. Hydrogen sulfide producing enzymes in pregnancy and preeclampsia. Placenta. 2012;33(6):518–521. doi:10.1016/j.placenta.2012.02.014
  • Xiao Q, Ying J, Xiang L, et al. The biologic effect of hydrogen sulfide and its function in various diseases. Medicine. 2018;97(44):e13065. doi:10.1097/MD.0000000000013065
  • Hu TX, Wang G, Guo XJ, et al. MiR 20a,-20b and −200c are involved in hydrogen sulfide stimulation of VEGF production in human placental trophoblasts. Placenta. 2016:39101. doi:10.1016/j.placenta.2016.01.019
  • Cindrova-Davies T, Herrera EA, Niu Y, et al. Reduced cystathionine gamma-lyase and increased miR-21 expression are associated with increased vascular resistance in growth-restricted pregnancies: hydrogen sulfide as a placental vasodilator. Am J Pathol. 2013;182(4):1448–1458. doi:10.1016/j.ajpath.2013.01.001
  • Sun Q, Chen Z, He P, et al. Reduced Expression of Hydrogen Sulfide-Generating Enzymes Down-Regulates 15-Hydroxyprostaglandin Dehydrogenase in Chorion during Term and Preterm Labor. Am J Pathol. 2018;188(1):63–71. doi:10.1016/j.ajpath.2017.09.006
  • You X, Chen Z, Zhao H, et al. Endogenous hydrogen sulfide contributes to uterine quiescence during pregnancy. Reproduction. 2017;153(5):535–543. doi:10.1530/REP-16-0549
  • Kim CJ, Romero R, Chaemsaithong P, et al. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. Am J Obstet Gynecol. 2015;213(4 Suppl):S29–52. doi:10.1016/j.ajog.2015.08.040
  • Redline RW. Classification of placental lesions. Am J Obstet Gynecol. 2015;213(4 Suppl):S21–28. doi:10.1016/j.ajog.2015.05.056
  • Osman I, Young A, Ledingham MA, et al. Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term. Mol Hum Reprod. 2003;9(1):41–45. doi:10.1093/molehr/gag001
  • Gomez-Lopez N, Romero R, Panaitescu B, et al. Inflammasome activation during spontaneous preterm labor with intra-amniotic infection or sterile intra-amniotic inflammation. Am J Reprod Immunol. 2018;80(5):e13049. doi:10.1111/aji.13049
  • Young A, Thomson AJ, Ledingham M, et al. Immunolocalization of proinflammatory cytokines in myometrium, cervix, and fetal membranes during human parturition at term. Biol Reprod. 2002;66(2):445–449. doi:10.1095/biolreprod66.2.445
  • Li H, Yu Y, Shi Y, et al. HoxA13 Stimulates Myometrial Cells to Secrete IL-1beta and Enhance the Expression of Contraction-Associated Proteins. Endocrinology. 2016;157(5):2129–2139. doi:10.1210/en.2015-2005
  • Liang Z, Sooranna SR, Engineer N, et al. Prostaglandin F2-alpha receptor regulation in human uterine myocytes. Mol Hum Reprod. 2008;14(4):215–223. doi:10.1093/molehr/gan008
  • Kinoshita T, Imamura R, Kushiyama H, et al. NLRP3 mediates NF-kappaB activation and cytokine induction in microbially induced and sterile inflammation. PLoS One. 2015;10(3):e0119179. doi:10.1371/journal.pone.0119179
  • Wang W, Wang X, Chun J, et al. Inflammasome-independent NLRP3 augments TGF-beta signaling in kidney epithelium. J Immunol. 2013;190(3):1239–1249. doi:10.4049/jimmunol.1201959
  • Zheng D, Dong S, Li T, et al. Exogenous Hydrogen Sulfide Attenuates Cardiac Fibrosis Through Reactive Oxygen Species Signal Pathways in Experimental Diabetes Mellitus Models. Cell Physiol Biochem. 2015;36(3):917–929. doi:10.1159/000430266
  • Yurinskaya MM, Krasnov GS, Kulikova DA, et al. H2S counteracts proinflammatory effects of LPS through modulation of multiple pathways in human cells. Inflamm Res. 2020;69(5):481–495. doi:10.1007/s00011-020-01329-x
  • Bhatia M. H2S and Inflammation: an Overview. Handb Exp Pharmacol. 2015;230:230165. doi:10.1007/978-3-319-18144-8_8
  • Sun L, Chen L, Wang F, et al. Exogenous hydrogen sulfide prevents lipopolysaccharide-induced inflammation by blocking the TLR4/NF-kappaB pathway in MAC-T cells. Gene. 2019:710114. doi:10.1016/j.gene.2019.05.033
  • Zhang GY, Lu D, Duan SF, et al. Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-kappaB Signaling Pathways. Oxid Med Cell Longev. 2018:20189647809. doi:10.1155/2018/9647809
  • Grishman EK, White PC, Savani RC. Toll-like receptors, the NLRP3 inflammasome, and interleukin-1beta in the development and progression of type 1 diabetes. Pediatr Res. 2012;71(6):626–632. doi:10.1038/pr.2012.24
  • Shimada K, Crother TR, Karlin J, et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 2012;36(3):401–414. doi:10.1016/j.immuni.2012.01.009
  • Dasu MR, Devaraj S, Zhao L, et al. High glucose induces toll-like receptor expression in human monocytes: mechanism of activation. Diabetes. 2008;57(11):3090–3098. doi:10.2337/db08-0564