86
Views
2
CrossRef citations to date
0
Altmetric
Original Research

Overexpression of Lin28a Aggravates Psoriasis-Like Phenotype by Regulating the Proliferation and Differentiation of Keratinocytes

, , , , , , , , , ORCID Icon, , ORCID Icon, , & ORCID Icon show all
Pages 4299-4312 | Published online: 30 Aug 2021

References

  • Krueger G, Ellis CN. Psoriasis–recent advances in understanding its pathogenesis and treatment. J Am Acad Dermatol. 2005;53(1 Suppl 1):S94–S100. doi:10.1016/j.jaad.2005.04.035
  • Bhosle MJ, Kulkarni A, Feldman SR, Balkrishnan R. Quality of life in patients with psoriasis. Health Qual Life Outcomes. 2006;4:35. doi:10.1186/1477-7525-4-35
  • Bovenschen HJ, Seyger MM, Van de Kerkhof PC. Plaque psoriasis vs. atopic dermatitis and lichen planus: a comparison for lesional T-cell subsets, epidermal proliferation and differentiation. Br J Dermatol. 2005;153(1):72–78. doi:10.1111/j.1365-2133.2005.06538.x
  • Benhadou F, Mintoff D, Del Marmol V. Psoriasis: keratinocytes or immune cells - which is the trigger? Dermatology. 2019;235(2):91–100. doi:10.1159/000495291
  • Chandra A, Ray A, Senapati S, Chatterjee R. Genetic and epigenetic basis of psoriasis pathogenesis. Mol Immunol. 2015;64(2):313–323. doi:10.1016/j.molimm.2014.12.014
  • Muller A, Hennig A, Lorscheid S, et al. IkappaBzeta is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes. Proc Natl Acad Sci U S A. 2018;115(40):10088–10093. doi:10.1073/pnas.1801377115
  • Shyh-Chang N, Daley GQ. Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell. 2013;12(4):395–406. doi:10.1016/j.stem.2013.03.005
  • Ustianenko D, Chiu HS, Treiber T, et al. LIN28 selectively modulates a subclass of let-7 MicroRNAs. Mol Cell. 2018;71(2):271–83e5. doi:10.1016/j.molcel.2018.06.029
  • Hawkes JE, Nguyen GH, Fujita M, et al. microRNAs in psoriasis. J Invest Dermatol. 2016;136(2):365–371. doi:10.1038/JID.2015.409
  • Liu Y, Liu Q. MicroRNAs as regulatory elements in psoriasis. Open Med. 2016;11(1):336–340. doi:10.1515/med-2016-0063
  • Pasquinelli AE, Reinhart BJ, Slack F, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000;408(6808):86–89. doi:10.1038/35040556
  • Zhao C, Sun G, Li S, et al. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc Natl Acad Sci U S A. 2010;107(5):1876–1881. doi:10.1073/pnas.0908750107
  • Wu Y, Liu L, Bian C, et al. MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis. Cell Commun Signal. 2018;16(1):58. doi:10.1186/s12964-018-0271-9
  • Albanesi C, Madonna S, Gisondi P, Girolomoni G. The interplay between keratinocytes and immune cells in the pathogenesis of psoriasis. Front Immunol. 2018;9:1549. doi:10.3389/fimmu.2018.01549
  • Nestle FO, Kaplan DH, Barker J. Psoriasis. N Engl J Med. 2009;361(5):496–509. doi:10.1056/NEJMra0804595
  • Wagner EF, Schonthaler HB, Guinea-Viniegra J, Tschachler E. Psoriasis: what we have learned from mouse models. Nat Rev Rheumatol. 2010;6(12):704–714. doi:10.1038/nrrheum.2010.157
  • Qin S, Wen J, Bai XC, et al. Endogenous n-3 polyunsaturated fatty acids protect against imiquimod-induced psoriasis-like inflammation via the IL-17/IL-23 axis. Mol Med Rep. 2014;9(6):2097–2104. doi:10.3892/mmr.2014.2136
  • Grossman RM, Krueger J, Yourish D, et al. Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proc Natl Acad Sci U S A. 1989;86(16):6367–6371. doi:10.1073/pnas.86.16.6367
  • Mak RK, Hundhausen C, Nestle FO. Progress in understanding the immunopathogenesis of psoriasis. Actas Dermosifiliogr. 2009;100(Suppl 2):2–13. doi:10.1016/s0001-7310(09)73372-1
  • Srivastava A, Nikamo P, Lohcharoenkal W, et al. MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis. J Allergy Clin Immunol. 2017;139(2):550–561. doi:10.1016/j.jaci.2016.07.025
  • Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol. 2009;10(8):857–863. doi:10.1038/ni.1767
  • Becher B, Pantelyushin S. Hiding under the skin: interleukin-17-producing γδ T cells go under the skin? Nat Med. 2012;18(12):1748–1750. doi:10.1038/nm.3016
  • Kagami S, Rizzo HL, Lee JJ, Koguchi Y, Blauvelt A. Circulating Th17, Th22, and Th1 cells are increased in psoriasis. J Invest Dermatol. 2010;130(5):1373–1383. doi:10.1038/jid.2009.399
  • Orlik C, Deibel D, Kublbeck J, et al. Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin. Cell Mol Immunol. 2020;17(4):380–394. doi:10.1038/s41423-019-0261-x
  • Li J, Li X, Hou R, et al. Psoriatic T cells reduce epidermal turnover time and affect cell proliferation contributed from differential gene expression. J Dermatol. 2015;42(9):874–880. doi:10.1111/1346-8138.12961
  • Sharma A, Saito Y, Hung SI, Naisbitt D, Uetrecht J, Bussiere J. The skin as a metabolic and immune-competent organ: implications for drug-induced skin rash. J Immunotoxicol. 2019;16(1):1–12. doi:10.1080/1547691x.2018.1514444
  • Albanesi C, De Pita O, Girolomoni G. Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes. Clin Dermatol. 2007;25(6):581–588. doi:10.1016/j.clindermatol.2007.08.013
  • Young PM, Parsi KK, Schupp CW, Armstrong AW. Psoriasis and wound healing outcomes: a retrospective cohort study examining wound complications and antibiotic use. Dermatol Online J. 2017;23(11). doi:10.5070/D32311037238
  • Xia J, Zhang W. MicroRNAs in normal and psoriatic skin. Physiol Genomics. 2014;46(4):113–122. doi:10.1152/physiolgenomics.00157.2013
  • Huang KF, Ma KH, Liu PS, Chen BW, Chueh SH. Baicalein increases keratin 1 and 10 expression in HaCaT keratinocytes via TRPV4 receptor activation. Exp Dermatol. 2016;25(8):623–629. doi:10.1111/exd.13024
  • D’Erme AM, Wilsmann-Theis D, Wagenpfeil J, et al. IL-36γ (IL-1F9) is a biomarker for psoriasis skin lesions. J Invest Dermatol. 2015;135(4):1025–1032. doi:10.1038/jid.2014.532
  • Boutet MA, Bart G, Penhoat M, et al. Distinct expression of interleukin (IL)-36α, β and γ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and crohn’s disease. Clin Exp Immunol. 2016;184(2):159–173. doi:10.1111/cei.12761
  • Mahil SK, Catapano M, Di Meglio P, et al. An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target. Sci Transl Med. 2017;9:411. doi:10.1126/scitranslmed.aan2514
  • Cai Y, Xue F, Quan C, et al. A critical role of the IL-1beta-IL-1R signaling pathway in skin inflammation and psoriasis pathogenesis. J Invest Dermatol. 2019;139(1):146–156. doi:10.1016/j.jid.2018.07.025
  • Zhang Y, Wang X, Zhong M, Zhang M, Suo Q, Lv K. MicroRNA let-7a ameliorates con A-induced hepatitis by inhibiting IL-6-dependent Th17 cell differentiation. J Clin Immunol. 2013;33(3):630–639. doi:10.1007/s10875-012-9840-7
  • Hu XP, Xie Q, Chen CF, Zhang W, Yu B. Let-7a inhibits T-cell proliferation and IFN-gamma secretion by down-regulating STAT3 expression in patients with psoriasis. Cell Physiol Biochem. 2017;42(1):115–125. doi:10.1159/000477120
  • Hua K, Deng X, Hu J, et al. Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer. J Exp Clin Cancer Res. 2020;39(1):58. doi:10.1186/s13046-020-01561-7