85
Views
16
CrossRef citations to date
0
Altmetric
Original Research

Melatonin Alleviates Age-Associated Endothelial Injury of Atherosclerosis via Regulating Telomere Function

, &
Pages 6799-6812 | Published online: 11 Dec 2021

References

  • Bentzon JF, Otsuka F, Virmani R, Falk E. Mechanisms of plaque formation and rupture. Circ Res. 2014;114(12):1852–1866. doi:10.1161/CIRCRESAHA.114.302721
  • Liu Y, Chen KJ. Atherosclerosis, vascular aging and therapeutic strategies. Chin J Integr Med. 2012;18(2):83–87. doi:10.1007/s11655-012-0996-z
  • Perk J, De Backer G, Gohlke H, et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J. 2012;33(13):1635–1701. doi:10.1093/eurheartj/ehs092
  • Benjamin EJ, Virani SS, Callaway CW, et al. Heart disease and stroke statistics-2018 update: a report from the American Heart Association. Circulation. 2018;137(12):e67–e492. doi:10.1161/CIR.0000000000000558
  • Sturlaugsdottir R, Aspelund T, Bjornsdottir G, et al. Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik study. BMJ Open. 2016;6(11):e012457. doi:10.1136/bmjopen-2016-012457
  • Shay JW, Wright WE. Telomeres and telomerase: three decades of progress. Nat Rev Genet. 2019;20(5):299–309. doi:10.1038/s41576-019-0099-1
  • Minamino T, Komuro I. Role of telomere in endothelial dysfunction in atherosclerosis. Curr Opin Lipidol. 2002;13(5):537–543. doi:10.1097/00041433-200210000-00010
  • Minamino T, Miyauchi H, Yoshida T, Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomeres in endothelial dysfunction. J Cardiol. 2003;41(1):39–40.
  • Doshida M, Ohmichi M, Tsutsumi S, et al. Raloxifene increases proliferation and up-regulates telomerase activity in human umbilical vein endothelial cells. J Biol Chem. 2006;281(34):24270–24278. doi:10.1074/jbc.M513251200
  • Bennaceur K, Atwill M, Al Zhrany N, et al. Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism. Atherosclerosis. 2014;236(2):312–320. doi:10.1016/j.atherosclerosis.2014.07.020
  • Pu DR, Liu L. HDL slowing down endothelial progenitor cells senescence: a novel anti-atherogenic property of HDL. Med Hypotheses. 2008;70(2):338–342. doi:10.1016/j.mehy.2007.05.025
  • Anderson G, Vaillancourt C, Maes M, Reiter RJ. Breastfeeding and the gut-brain axis: is there a role for melatonin? Biomol Concepts. 2017;8(3–4):185–195. doi:10.1515/bmc-2017-0009
  • Yang Y, Sun Y, Yi W, et al. A review of melatonin as a suitable antioxidant against myocardial ischemia-reperfusion injury and clinical heart diseases. J Pineal Res. 2014;57(4):357–366. doi:10.1111/jpi.12175
  • Hu ZP, Fang XL, Fang N, et al. Melatonin ameliorates vascular endothelial dysfunction, inflammation, and atherosclerosis by suppressing the TLR4/NF-kappaB system in high-fat-fed rabbits. J Pineal Res. 2013;55(4):388–398. doi:10.1111/jpi.12085
  • Hung MW, Kravtsov GM, Lau CF, Poon AM, Tipoe GL, Fung ML. Melatonin ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in rats with chronic intermittent hypoxia. J Pineal Res. 2013;55(3):247–256. doi:10.1111/jpi.12067
  • Dominguez-Rodriguez A, Abreu-Gonzalez P, Reiter RJ. The potential usefulness of serum melatonin level to predict heart failure in patients with hypertensive cardiomyopathy. Int J Cardiol. 2014;174(2):415–417. doi:10.1016/j.ijcard.2014.04.044
  • Bhattacharya S, Patel KK, Dehari D, Agrawal AK, Singh S. Melatonin and its ubiquitous anticancer effects. Mol Cell Biochem. 2019;462(1–2):133–155. doi:10.1007/s11010-019-03617-5
  • Habtemariam S, Daglia M, Sureda A, Selamoglu Z, Gulhan MF, Nabavi SM. Melatonin and respiratory diseases: a review. Curr Top Med Chem. 2017;17(4):467–488. doi:10.2174/1568026616666160824120338
  • Chen D, Zhang T, Lee TH. Cellular mechanisms of melatonin: insight from neurodegenerative diseases. Biomolecules. 2020;10(8):Aug. doi:10.3390/biom10081158
  • Miller KP, Ramos KS. Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons. Drug Metab Rev. 2001;33(1):1–35. doi:10.1081/dmr-100000138
  • Iwano S, Asanuma F, Nukaya M, Saito T, Kamataki T. CYP1A1-mediated mechanism for atherosclerosis induced by polycyclic aromatic hydrocarbons. Biochem Biophys Res Commun. 2005;337(2):708–712. doi:10.1016/j.bbrc.2005.09.109
  • Mohammed K, Shervington A. Can CYP1A1 siRNA be an effective treatment for lung cancer? Cell Mol Biol Lett. 2008;13(2):240–249. doi:10.2478/s11658-007-0050-x
  • Kimura M, Stone RC, Hunt SC, et al. Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths. Nat Protoc. 2010;5(9):1596–1607. doi:10.1038/nprot.2010.124
  • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science. 1994;266(5193):2011–2015. doi:10.1126/science.7605428
  • Zheng Z, Wang M, Cheng C, et al. Ginsenoside Rb1 reduces H2O2induced HUVEC dysfunction by stimulating the sirtuin-1/AMPactivated protein kinase pathway. Mol Med Rep. 2020;22(1):247–256. doi:10.3892/mmr.2020.11096
  • Wang JC, Bennett M. Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circ Res. 2012;111(2):245–259. doi:10.1161/CIRCRESAHA.111.261388
  • Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation. 2002;105(13):1541–1544. doi:10.1161/01.cir.0000013836.85741.17
  • Nazari-Shafti TZ, Cooke JP. Telomerase therapy to reverse cardiovascular senescence. Methodist DeBakey Cardiovasc J. 2015;11(3):172–175. doi:10.14797/mdcj-11-3-172
  • Hsiao R, Sharma HW, Ramakrishnan S, Keith E, Narayanan R. Telomerase activity in normal human endothelial cells. Anticancer Res. 1997;17(2A):827–832.
  • Yang J, Chang E, Cherry AM, et al. Human endothelial cell life extension by telomerase expression. J Biol Chem. 1999;274(37):26141–26148. doi:10.1074/jbc.274.37.26141
  • Zhang H, Hu N. Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway. Mol Med Rep. 2018;18(2):1345–1352. doi:10.3892/mmr.2018.9119
  • Martinez-Campa CM, Alonso-Gonzalez C, Mediavilla MD, Cos S, Gonzalez A, Sanchez-Barcelo EJ. Melatonin down-regulates hTERT expression induced by either natural estrogens (17beta-estradiol) or metalloestrogens (cadmium) in MCF-7 human breast cancer cells. Cancer Lett. 2008;268(2):272–277. doi:10.1016/j.canlet.2008.04.001
  • Blasiak J, Reiter RJ, Kaarniranta K. Melatonin in retinal physiology and pathology: the case of age-related macular degeneration. Oxid Med Cell Longev. 2016;2016:6819736. doi:10.1155/2016/6819736
  • Barouki R, Morel Y. Repression of cytochrome P450 1A1 gene expression by oxidative stress: mechanisms and biological implications. Biochem Pharmacol. 2001;61(5):511–516. doi:10.1016/s0006-2952(00)00543-8
  • Huang B, Bao J, Cao YR, Gao HF, Jin Y. Cytochrome P450 1A1 (CYP1A1) catalyzes lipid peroxidation of oleic acid-induced HepG2 cells. Biochemistry (Mosc). 2018;83(5):595–602. doi:10.1134/S0006297918050127
  • Lefevre L, Authier H, Stein S, et al. LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPARgamma ligand synthesis. Nat Commun. 2015;6:6801. doi:10.1038/ncomms7801
  • Kahn-Kirby AH, Amagata A, Maeder CI, et al. Targeting ferroptosis: a novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy. PLoS One. 2019;14(3):e0214250. doi:10.1371/journal.pone.0214250
  • Mahipal SV, Subhashini J, Reddy MC, et al. Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and 15-(S)-HETE on chronic myelogenous leukemia cell line K-562: reactive oxygen species (ROS) mediate caspase-dependent apoptosis. Biochem Pharmacol. 2007;74(2):202–214. doi:10.1016/j.bcp.2007.04.005
  • Shen T, Ma J, Zhang L, et al. Positive feedback-loop of telomerase reverse transcriptase and 15-lipoxygenase-2 promotes pulmonary hypertension. PLoS One. 2013;8(12):e83132. doi:10.1371/journal.pone.0083132
  • Farhat N, Thorin-Trescases N, Voghel G, et al. Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers. Can J Physiol Pharmacol. 2008;86(11):761–769. doi:10.1139/Y08-082
  • Herbig U, Jobling WA, Chen BP, Chen DJ, Sedivy JM. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell. 2004;14(4):501–513. doi:10.1016/s1097-2765(04)00256-4
  • Purvis JE, Karhohs KW, Mock C, Batchelor E, Loewer A, Lahav G. p53 dynamics control cell fate. Science. 2012;336(6087):1440–1444. doi:10.1126/science.1218351
  • Chi C, Li DJ, Jiang YJ, et al. Vascular smooth muscle cell senescence and age-related diseases: state of the art. Biochim Biophys Acta Mol Basis Dis. 2019;1865(7):1810–1821. doi:10.1016/j.bbadis.2018.08.015
  • Endorf EB, Qing H, Aono J, et al. Telomerase reverse transcriptase deficiency prevents neointima formation through chromatin silencing of E2F1 target genes. Arterioscler Thromb Vasc Biol. 2017;37(2):301–311. doi:10.1161/ATVBAHA.116.308717
  • Wang J, Uryga AK, Reinhold J, et al. Vascular smooth muscle cell senescence promotes atherosclerosis and features of plaque vulnerability. Circulation. 2015;132(20):1909–1919. doi:10.1161/CIRCULATIONAHA.115.016457