Maternal High-Fat Diet Programs Renal Peroxisomes and Activates NLRP3 Inflammasome-Mediated Pyroptosis in the Rat Fetus

References

• Bray GA, Kim KK, Wilding JPH. Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation. Obes Rev. 2017;18(7):715–723. doi:10.1111/obr.12551
   PubMed Web of Science ®Google Scholar
• Martínez-Hortelano JA, Berlanga-Macías C, Pozuelo-Carrascosa DP, Sanabria-Martínez G, Poyatos-León R, Martínez-Vizcaíno V. Interpregnancy weight change and perinatal outcomes: a protocol for a systematic review and meta-analysis. Medicine. 2019;98(20):e15470–e15470. doi:10.1097/MD.0000000000015470
   PubMed Web of Science ®Google Scholar
• Chang E, Hafner H, Varghese M, et al. Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation. Sci Rep. 2019;9(1):16027. doi:10.1038/s41598-019-52583-x
   PubMedGoogle Scholar
• Gillman MW, Rifas-Shiman S, Berkey CS, Field AE, Colditz GA. Maternal gestational diabetes, birth weight, and adolescent obesity. Pediatrics. 2003;111(3):e221–226. doi:10.1542/peds.111.3.e221
   PubMed Web of Science ®Google Scholar
• Boney CM, Verma A, Tucker R, Vohr BR. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics. 2005;115(3):e290–e296. doi:10.1542/peds.2004-1808
   PubMed Web of Science ®Google Scholar
• Reynolds RM, Osmond C, Phillips DI, Godfrey KM. Maternal BMI, parity, and pregnancy weight gain: influences on offspring adiposity in young adulthood. J Clin Endocrinol Metab. 2010;95(12):5365–5369. doi:10.1210/jc.2010-0697
   PubMed Web of Science ®Google Scholar
• Lee YQ, Collins CE, Gordon A, Rae KM, Pringle KG. The relationship between maternal obesity and diabetes during pregnancy on offspring kidney structure and function in humans: a systematic review. J Dev Orig Health Dis. 2019;10(4):406–419. doi:10.1017/S2040174418000867
   PubMed Web of Science ®Google Scholar
• Glastras SJ, Chen H, Teh R, et al. Mouse models of diabetes, obesity and related kidney disease. PLoS One. 2016;11(8):8. doi:10.1371/journal.pone.0162131
   Web of Science ®Google Scholar
• Kett MM, Denton KM. Renal programming: cause for concern? Am J Physiol Regul Integr Comp Physiol. 2011;300(4):R791–803. doi:10.1152/ajpregu.00791.2010
   PubMed Web of Science ®Google Scholar
• Bruce KD, Cagampang FR, Argenton M, et al. Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology. 2009;50(6):1796–1808. doi:10.1002/hep.23205
   PubMed Web of Science ®Google Scholar
• Zambrano E, Ibáñez C, Martínez-Samayoa PM, Lomas-Soria C, Durand-Carbajal M, Rodríguez-González GL. Maternal obesity: lifelong metabolic outcomes for offspring from poor developmental trajectories during the perinatal period. Arch Med Res. 2016;47(1):1–12. doi:10.1016/j.arcmed.2016.01.004
   PubMed Web of Science ®Google Scholar
• Marseglia L, Manti S, D’Angelo G, et al. Oxidative stress in obesity: a critical component in human diseases. Int J Mol Sci. 2014;16(1):378–400. doi:10.3390/ijms16010378
   PubMed Web of Science ®Google Scholar
• Moldovan L, Moldovan NI. Oxygen free radicals and redox biology of organelles. Histochem Cell Biol. 2004;122(4):395–412.
   PubMed Web of Science ®Google Scholar
• Ermak G, Davies KJA. Calcium and oxidative stress: from cell signaling to cell death. Mol Immunol. 2002;38(10):713–721. doi:10.1016/S0161-5890(01)00108-0
   PubMed Web of Science ®Google Scholar
• Islinger M, Voelkl A, Fahimi HD, Schrader M. The peroxisome: an update on mysteries 2.0. Histochem Cell Biol. 2018;150(5):443–471.
   PubMed Web of Science ®Google Scholar
• Zheng R, Tao L, Jian H, et al. NLRP3 inflammasome activation and lung fibrosis caused by airborne fine particulate matter. Ecotoxicol Environ Saf. 2018;163:612–619. doi:10.1016/j.ecoenv.2018.07.076
   PubMed Web of Science ®Google Scholar
• Seervi M, Rani A, Sharma AK, Santhosh Kumar TR. ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine. Biomed Pharmacother. 2018;106:200–209. doi:10.1016/j.biopha.2018.06.123
   PubMed Web of Science ®Google Scholar
• Gao W, Zhang KZ. RBP4 induces pyroptosis in cardiomyocytes via activating NLRP3/Caspase-1/GSDMD pathway in acute myocardial infarction. Eur Heart J. 2020;41(Supplement_2):ehaa946–ehaa3641. doi:10.1093/ehjci/ehaa946.3641
   Google Scholar
• Sasakura H, Moribe H, Nakano M, Ikemoto K, Takeuchi K, Mori I. Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in C. elegans. J Cell Sci. 2017;130(15):2631–2643.
   PubMed Web of Science ®Google Scholar
• Akagawa M, Nakano M, Ikemoto K. Recent progress in studies on the health benefits of pyrroloquinoline quinone. Bioscience, Biotechnology, and Biochemistry. 2016;80(1):3–22. doi:10.1080/09168451.2015.1062715
   Google Scholar
• Park S, Jang A, Bouret SG. Maternal obesity-induced endoplasmic reticulum stress causes metabolic alterations and abnormal hypothalamic development in the offspring. PLoS Biol. 2020;18(3):e3000296–e3000296. doi:10.1371/journal.pbio.3000296
   PubMed Web of Science ®Google Scholar
• Nüsken E, Turnwald E-M, Fink G, et al. Maternal high fat diet and in-utero metformin exposure significantly impact upon the fetal renal proteome of male mice. J Clin Med. 2019;8(5):663. doi:10.3390/jcm8050663
   PubMed Web of Science ®Google Scholar
• Hammoud R, Pannia E, Kubant R, et al. Maternal choline intake programs hypothalamic energy regulation and later-life phenotype of male Wistar rat offspring. Mol Nutr Food Res. 2020;64(9):1901178. doi:10.1002/mnfr.201901178
   Web of Science ®Google Scholar
• Glastras SJ, Chen H, Tsang M, et al. The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PLoS One. 2017;12(2):e0172644–e0172644. doi:10.1371/journal.pone.0172644
   PubMed Web of Science ®Google Scholar
• Glastras SJ, Tsang M, Teh R, et al. Maternal obesity promotes diabetic nephropathy in rodent offspring. Sci Rep. 2016;6(1):27769. doi:10.1038/srep27769
   PubMedGoogle Scholar
• Glastras SJ, Chen H, Pollock CA, Saad S. Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring. Biosci Rep. 2018;38(2):2. doi:10.1042/BSR20180050
   Google Scholar
• Hokke S, Puelles VG, Armitage JA, Fong K, Bertram JF, Cullen-McEwen LA. Maternal fat feeding augments offspring nephron endowment in mice. PLoS One. 2016;11(8):e0161578. doi:10.1371/journal.pone.0161578
   PubMed Web of Science ®Google Scholar
• Holemans K, Caluwaerts S, Poston L, van Assche FA. Diet-induced obesity in the rat: a model for gestational diabetes mellitus. Am J Obstet Gynecol. 2004;190(3):858–865. doi:10.1016/j.ajog.2003.09.025
   PubMed Web of Science ®Google Scholar
• Yamashita S-I, Fujiki Y. Assessing pexophagy in mammalian cells. In: Schrader M, editor. Peroxisomes: Methods and Protocols. New York: Springer New York; 2017:243–248.
   Google Scholar
• Jansen RLM, Santana-Molina C, van den Noort M, Devos DP, van der Klei IJ. Comparative genomics of peroxisome biogenesis proteins: making sense of the PEX proteins. Front Cell Dev Biol. 2021;9:1229. doi:10.3389/fcell.2021.654163
   Web of Science ®Google Scholar
• Summerer S, Hanano A, Utsumi S, Arand M, Schuber F, Blée E. Stereochemical features of the hydrolysis of 9,10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases. Biochem J. 2002;366(Pt 2):471–480. doi:10.1042/bj20011778
   PubMedGoogle Scholar
• Jiang W, Geng H, Lv X, et al. Idebenone protects against atherosclerosis in apolipoprotein E-deficient mice via activation of the SIRT3-SOD2-mtROS pathway. Cardiovasc Drugs Ther. 2020. doi:10.1007/s10557-020-07018-5
   Web of Science ®Google Scholar
• Brown GC, Borutaite V. Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochim Biophys Acta Bioener. 2004;1658(1):44–49. doi:10.1016/j.bbabio.2004.03.016
   Web of Science ®Google Scholar
• Tanaka H, Okazaki T. Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway. J Cell Sci. 2019;132:11.
   Web of Science ®Google Scholar
• Ke B, Shen W, Fang X, Wu Q. The NLPR3 inflammasome and obesity-related kidney disease. J Cell Mol Med. 2018;22(1):16–24. doi:10.1111/jcmm.13333
   PubMed Web of Science ®Google Scholar
• Bryant CE, Fitzgerald KA. Molecular mechanisms involved in inflammasome activation. Trends Cell Biol. 2009;19(9):455–464. doi:10.1016/j.tcb.2009.06.002
   PubMed Web of Science ®Google Scholar
• Chen X, Guo X, Ge Q, Zhao Y, Mu H, Zhang J. ER stress activates the NLRP3 inflammasome: a novel mechanism of atherosclerosis. Oxid Med Cell Longev. 2019;2019:3462530. doi:10.1155/2019/3462530
   PubMed Web of Science ®Google Scholar
• Oslowski CM, Hara T, O’Sullivan-Murphy B, et al. Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome. Cell Metab. 2012;16(2):265–273. doi:10.1016/j.cmet.2012.07.005
   PubMed Web of Science ®Google Scholar
• Zhou J, Chng WJ. Roles of thioredoxin binding protein (TXNIP) in oxidative stress, apoptosis and cancer. Mitochondrion. 2013;13(3):163–169. doi:10.1016/j.mito.2012.06.004
   PubMed Web of Science ®Google Scholar
• Hafner-Bratkovič I, Pelegrín P. Ion homeostasis and ion channels in NLRP3 inflammasome activation and regulation. Curr Opin Immunol. 2018;52:8–17. doi:10.1016/j.coi.2018.03.010
   PubMed Web of Science ®Google Scholar
• Harris CB, Chowanadisai W, Mishchuk DO, Satre MA, Slupsky CM, Rucker RB. Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects. J Nutr Biochem. 2013;24(12):2076–2084. doi:10.1016/j.jnutbio.2013.07.008
   PubMed Web of Science ®Google Scholar
• Jonscher KR, Stewart MS, Alfonso-Garcia A, et al. Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice. FASEB J. 2017;31(4):1434–1448. doi:10.1096/fj.201600906R
   PubMed Web of Science ®Google Scholar
• Friedman JE, Dobrinskikh E, Alfonso-Garcia A, et al. Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice. Hepatol Commun. 2018;2(3):313–328. doi:10.1002/hep4.1139
   PubMed Web of Science ®Google Scholar
• Jo DS, Bae D-J, Park SJ, et al. Pexophagy is induced by increasing peroxisomal reactive oxygen species in 1′10-phenanthroline-treated cells. Biochem Biophys Res Commun. 2015;467(2):354–360. doi:10.1016/j.bbrc.2015.09.153
   PubMed Web of Science ®Google Scholar