Caffeic Acid Phenethyl Ester reduces Pro Inflammatory Cytokines in Moderate Swimming Test in Growing Rats Model

References

• Ley K, Laudanna C, Cybulsky MI, Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7:678–689. doi:10.1038/nri2156
   PubMed Web of Science ®Google Scholar
• Oguntibeju OO. Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links. Int J Physiol Pathophysiol Pharmacol. 2019;11(3):45–63.
   PubMedGoogle Scholar
• Abrahamsen B, Bonnevie-Nielsen V, Ebbesen EN, Gram J, Beck-Nielsen H. Cytokines and bone loss in a 5-year longitudinal study hormone replacement therapy suppresses serum soluble interleukin-6 receptor and increases interleukin-1-receptor antagonist: the Danish Osteoporosis Prevention Study. J Bone Miner Res. 2000;5(8):1545–1554. doi:10.1359/jbmr.2000.15.8.1545
   Google Scholar
• Axelrad JE, Lichtiger S, Yajnik V. Inflammatory bowel disease and cancer: the role of inflammation, immunosuppression, and cancer treatment. World J Gastroenterol. 2016;22(20):4794–4801. doi:10.3748/wjg.v22.i20.4794
   PubMed Web of Science ®Google Scholar
• Schumacher A, Seljeflot I, Sommervoll L, Christensen B, Otterstad JE, Arnesen H. Increased levels of markers of vascular inflammation in patients with coronary heart disease. Scand J Clin Lab Invest. 2002;62(1):59–68. doi:10.1080/003655102753517217
   PubMed Web of Science ®Google Scholar
• Pedersen M, Bruunsgaard H, Weis N, et al. Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes. Mech Ageing Dev. 2003;24(4):495–502. doi:10.1016/S0047-6374(03)00027-7
   Google Scholar
• Bruunsgaard H. The clinical impact of systemic low-level inflammation in elderly populations. Dan Med Bull. 2006;53(3):285–309.
   PubMedGoogle Scholar
• Allen J, Sun Y, Woods JA. Exercise and the regulation of inflammatory responses. Prog Mol Biol Transl Sci. 2015. doi:10.1016/bs.pmbts.2015.07.003
   PubMed Web of Science ®Google Scholar
• Furman D, Campisi J, Verdin E, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25(12):1822–1832. doi:10.1038/s41591-019-0675-0
   PubMed Web of Science ®Google Scholar
• Stow JL, Murray RZ. Intracellular trafficking and secretion of inflammatory cytokines. Cytokine Growth Factor Rev. 2013;24(3):227–239. doi:10.1016/j.cytogfr.2013.04.001
   PubMed Web of Science ®Google Scholar
• Starkie RL, Hargreaves M, Rolland J, Febbraio MA. Heat stress, cytokines, and the immune response to exercise. Brain Behav Immun. 2005;19(5):404–412. doi:10.1016/j.bbi.2005.03.005
   PubMed Web of Science ®Google Scholar
• Silveira LS, de Moura Mello Antunes B, Luis Araujo Minari A, Vagner Thomatieli Dos Santos R, Rosa Neto JC, Santos Lira F. Macrophage polarization: implications on metabolic diseases and the role of exercise. Crit Rev Eukaryot Gene Expr. 2016;19(5):404–412. doi:10.1615/CritRevEukaryotGeneExpr.2016015920
   Google Scholar
• Pendersen BK, Toft AD. Effects of exercise on lymphocytes and cytokines. Br J Sports Med. 2000. doi:10.1136/bjsm.34.4.246
   Web of Science ®Google Scholar
• Bernecker C, Scherr J, Schinner S, Braun S, Scherbaum WA, Halle M. Evidence for an exercise induced increase of TNF-α and IL-6 in marathon runners. Scand J Med Sci Sport. 2013;23(2):207–214. doi:10.1111/j.1600-0838.2011.01372.x
   PubMed Web of Science ®Google Scholar
• Oishi Y, Manabe I. Macrophages in inflammation, repair and regeneration. Int Immunol. 2018. doi:10.1093/intimm/dxy054
   PubMed Web of Science ®Google Scholar
• Brenner IKM, Natale VM, Vasiliou P, Moldoveanu AI, Shek PN, Shephard RJ. Impact of three different types of exercise on components of the inflammatory response. Eur J Appl Physiol Occup Physiol. 1999;80(5):452–460. doi:10.1007/s004210050617
   PubMed Web of Science ®Google Scholar
• Cerqueira É, Marinho DA, Neiva HP, Lourenço O. Inflammatory effects of high and moderate intensity exercise—a systematic review. Front Physiol. 2020;10. doi:10.3389/fphys.2019.01550
   PubMed Web of Science ®Google Scholar
• Pedersen BK. Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease. Eur J Clin Invest. 2017;47(8):600–611. doi:10.1111/eci.12781
   PubMed Web of Science ®Google Scholar
• Göçer H, Gülçin I. Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties. Int J Food Sci Nutr. 2011;62(8):821–825. doi:10.3109/09637486.2011.585963
   PubMed Web of Science ®Google Scholar
• Cho MS, Park WS, Jung WK, et al. Caffeic acid phenethyl ester promotes anti-inflammatory effects by inhibiting MAPK and NF-κB signaling in activated HMC-1 human mast cells. Pharm Biol. 2014;52(7):926–932. doi:10.3109/13880209.2013.865243
   PubMed Web of Science ®Google Scholar
• Tolba MF, Azab SS, Khalifa AE, Abdel-Rahman SZ, Abdel-Naim AB. Caffeic acid phenethyl ester, a promising component of propolis with a plethora of biological activities: a review on its anti-inflammatory, neuroprotective, hepatoprotective, and cardioprotective effects. IUBMB Life. 2013;65(8):699–709. doi:10.1002/iub.1189
   PubMed Web of Science ®Google Scholar
• Park JH, Lee JK, Kim HS, et al. Immunomodulatory effect of caffeic acid phenethyl ester in Balb/c mice. Int Immunopharmacol. 2004;4(3):429–436. doi:10.1016/j.intimp.2004.01.013
   PubMed Web of Science ®Google Scholar
• Lee YJ, Liao PH, Chen WK, Yang CC. Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells. Cancer Lett. 2000;153(1–2):51–56. doi:10.1016/S0304-3835(00)00389-X
   PubMed Web of Science ®Google Scholar
• Macías-Pérez JR, Beltrán-Ramírez O, Vásquez-Garzón VR, et al. The effect of caffeic acid phenethyl ester analogues in a modified resistant hepatocyte model. Anticancer Drugs. 2013;24(4):394–405. doi:10.1097/CAD.0b013e32835e9743
   PubMed Web of Science ®Google Scholar
• Cechella JL, Leite MR, Dobrachinski F, et al. Moderate swimming exercise and caffeine supplementation reduce the levels of inflammatory cytokines without causing oxidative stress in tissues of middle-aged rats. Amino Acids. 2014;46(5):1187–1195. doi:10.1007/s00726-014-1679-1
   PubMed Web of Science ®Google Scholar
• Middelbeek RJW, Motiani P, Brandt N, et al. Exercise intensity regulates cytokine and klotho responses in men. Nutr Diabetes. 2021;11(1):5. doi:10.1038/s41387-020-00144-x
   PubMed Web of Science ®Google Scholar
• Shen YC, Yen JC, Liou KT. Ameliorative effects of caffeic acid phenethyl ester on an eccentric exercise-induced skeletal muscle injury by down-regulating NF-κB mediated inflammation. Pharmacology. 2013;91(3–4):219–228. doi:10.1159/000348412
   PubMed Web of Science ®Google Scholar
• Akil M. Effects of caffeic acid phenethyl ester and oxidative stress caused by the exhaustion exercise on endotelial damage. Arch Ital Biol. 2020;158(2):37–44. doi:10.12871/00039829202021
   PubMed Web of Science ®Google Scholar
• Yudkin JS. Inflammation, obesity, and the metabolic syndrome. Horm Metab Res. 2007;39(10):707–709. doi:10.1055/s-2007-985898
   PubMed Web of Science ®Google Scholar
• Orban Z, Mitsiades N, Burke TR, Tsokos M, Chrousos GP. Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation. Neuroimmunomodulation. 2000;7(2):99–105. doi:10.1159/000026427
   PubMed Web of Science ®Google Scholar
• Toyoda T, Tsukamoto T, Takasu S, et al. Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-κB inhibitor, on Helicobacter pylori-induced gastritis in Mongolian gerbils. Int J Cancer. 2009;125(8):1786–1795. doi:10.1002/ijc.24586
   PubMed Web of Science ®Google Scholar
• Mathieu P, Poirier P, Pibarot P, Lemieux I, Després JP. Visceral obesity the link among inflammation, hypertension, and cardiovascular disease. Hypertension. 2009;53(4):577–584. doi:10.1161/HYPERTENSIONAHA.108.110320
   PubMed Web of Science ®Google Scholar