Antioxidant and Anti-inflammatory Properties Mediate the Neuroprotective Effects of Hydro-ethanolic Extract of Tiliacora triandra Against Cisplatin-induced Neurotoxicity

References

• Ongnok B, Chattipakorn N, Chattipakorn SC. Doxorubicin and cisplatin induced cognitive impairment: the possible mechanisms and interventions. Exp Neurol. 2020;324:113118. doi:10.1016/j.expneurol.2019.113118
   PubMed Web of Science ®Google Scholar
• Oun R, Moussa YE, Wheate NJ. The side effects of platinum-based chemotherapy drugs: a review for chemists. Dalton Trans. 2018;47:6645–6653. doi:10.1039/C8DT00838H
   PubMed Web of Science ®Google Scholar
• Stankovic JSK, Selakovic D, Mihailovic V, Rosic G. Antioxidant supplementation in the treatment of neurotoxicity induced by platinum-based chemotherapeutics-A review. Int J Mol Sci. 2020;21:7753. doi:10.3390/ijms21207753
   PubMed Web of Science ®Google Scholar
• Falzone L, Salomone S, Libra M. Evolution of cancer pharmacological treatments at the turn of the third millennium. Front Pharmacol. 2018;9:1300. doi:10.3389/fphar.2018.01300
   PubMed Web of Science ®Google Scholar
• Zhou W, Kavelaars A, Heijnen CJ. Metformin prevents cisplatin-induced cognitive impairment and brain damage in mice. PLoS One. 2016;11(3):e0151890. doi:10.1371/journal.pone.0151890
   PubMed Web of Science ®Google Scholar
• Kim SJ, Park C, Lee JN, Park R. Protective roles of fenofibrate against cisplatin-induced ototoxicity by the rescue of peroxisomal and mitochondrial dysfunction. Toxicol Appl Pharmacol. 2018;353:43–54. doi:10.1016/j.taap.2018.06.010
   PubMed Web of Science ®Google Scholar
• Wang L, He Y, Li Y, et al. Protective effects of nucleosides-rich extract from Cordyceps cicadae against cisplatin induced testicular damage. Chem Biodivers. 2020;11:e2000671.
   Google Scholar
• Yin M, Li N, Makinde EA, Olatunji OJ, Ni ZN. N6-2-hydroxyethyl-adenosine ameliorate cisplatin induced acute kidney injury in mice. All Life. 2020;13:244–251. doi:10.1080/26895293.2020.1760149
   Web of Science ®Google Scholar
• Wang L, Apple AC, Schroeder MP, et al. Reduced prefrontal activation during working and long-term memory tasks and impaired patient-reported cognition among cancer survivors post chemotherapy compared with healthy controls. Cancer. 2016;122:258–268. doi:10.1002/cncr.29737
   PubMed Web of Science ®Google Scholar
• Chtourou Y, Gargouri B, Kebieche M, Fetoui H. Naringin abrogates cisplatin-induced cognitive deficits and cholinergic dysfunction through the down-regulation of AChE expression and iNOS signaling pathways in hippocampus of aged rats. J Mol Neurosci. 2015;56(2):349–362. doi:10.1007/s12031-015-0547-0
   PubMed Web of Science ®Google Scholar
• Salih NA, Al-Baggou BK. Effect of memantine hydrochloride on cisplatin-induced neurobehavioral toxicity in mice. Acta Neurol Belg. 2020;120(1):71–82. doi:10.1007/s13760-019-01161-z
   PubMed Web of Science ®Google Scholar
• Makinde EA, Radenahmad N, Adekoya AE, Olatunji OJ. Tiliacora triandra extract possesses antidiabetic effects in high fat diet/streptozotocin-induced diabetes in rats. J Food Biochem. 2020;44(6):e13239. doi:10.1111/jfbc.13239
   PubMed Web of Science ®Google Scholar
• Makinde EA, Ovatlarnporn C, Adekoya AE, Nwabor OF, Olatunji OJ. Antidiabetic, antioxidant and antimicrobial activity of the aerial part of Tiliacora triandra. S Afr J Bot. 2019;125:337–343. doi:10.1016/j.sajb.2019.08.012
   Web of Science ®Google Scholar
• Phunchago N, Wattanathorn J, Chaisiwamongkol K. Tiliacora triandra, an anti-intoxication plant, improves memory impairment, neurodegeneration, cholinergic function, and oxidative stress in hippocampus of ethanol dependence rats. Oxid Med Cell Longev. 2015;2015:918426. doi:10.1155/2015/918426
   PubMed Web of Science ®Google Scholar
• Song P, Sun C, Li J, et al. Tiliacora triandra extract and its major constituent attenuates diabetic kidney and testicular impairment by modulating redox imbalance and pro-inflammatory responses in rats. J Sci Food Agric. 2021;101:1598–1608. doi:10.1002/jsfa.10779
   PubMed Web of Science ®Google Scholar
• Thong-Asa W, Bullangpoti V. Neuroprotective effects of Tiliacora triandra leaf extract in a mice model of cerebral ischemia reperfusion. Avicenna J Phytomed. 2020;10:202–212.
   PubMed Web of Science ®Google Scholar
• Thong-Asa W, Tumkiratiwong P, Bullangpoti V, Kongnirundonsuk K, Tilokskulchai K. Tiliacora triandra (Colebr.) Diels leaf extract enhances spatial learning and learning flexibility and prevents dentate gyrus neuronal damage induced by cerebral ischemia/reperfusion injury in mice. Avicenna J Phytomed. 2017;7:389–400.
   PubMedGoogle Scholar
• Liu C, Ma M, Wen C, Uz Zaman R, Olatunji OJ. Antiallodynic and anti-hyperalgesia effects of Tiliacora triandra against cisplatin-induced peripheral neuropathy. All Life. 2021;14:441–449. doi:10.1080/26895293.2021.1927204
   Web of Science ®Google Scholar
• Chen X, Famurewa AC, Tang J, Olatunde OO, Olatunji OJ. Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-α/NF-κB/caspase-3 signaling in type 2 diabetes rats. Nutr Neurosci. 2021;16:1–11. doi:10.1080/1028415X.2021.1901047
   Google Scholar
• Wall PM, Messier C. Infralimbic kappa opioid and muscarinic M1 receptor interactions in the concurrent modulation of anxiety and memory. Psychopharmacology. 2002;160:233–244. doi:10.1007/s00213-001-0979-9
   PubMed Web of Science ®Google Scholar
• Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959;82:70–77. doi:10.1016/0003-9861(59)90090-6
   PubMed Web of Science ®Google Scholar
• Ahmad ST, Arjumand W, Seth A, et al. Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. Toxicol. 2011;290:69–81. doi:10.1016/j.tox.2011.08.020
   PubMed Web of Science ®Google Scholar
• El‐Deeb OS, Soliman GM, Elesawy RO. Linagliptin, the dipeptidyl peptidase‐4 enzyme inhibitor, lessens CHOP and GRP78 biomarkers levels in cisplatin‐induced neurobehavioral deficits: a possible restorative gateway. J Biochem Mol Toxicol. 2020;34:e22541. doi:10.1002/jbt.22541
   Web of Science ®Google Scholar
• Park YJ, Kim KS, Park JH, et al. Protective effects of dendropanoxide isolated from Dendropanax morbifera against cisplatin-induced acute kidney injury via the AMPK/mTOR signaling pathway. Food Chem Toxicol. 2020;145:111605. doi:10.1016/j.fct.2020.111605
   PubMed Web of Science ®Google Scholar
• Chen X, Wei W, Li Y, Huang J, Ci X. Hesperetin relieves cisplatin-induced acute kidney injury by mitigating oxidative stress, inflammation and apoptosis. Chem Biol Interact. 2019;308:269–278. doi:10.1016/j.cbi.2019.05.040
   PubMed Web of Science ®Google Scholar
• Potočnjak I, Marinić J, Batičić L, Šimić L, Broznić D, Domitrović R. Aucubin administered by either oral or parenteral route protects against cisplatin-induced acute kidney injury in mice. Food Chem Toxicol. 2020;142:111472. doi:10.1016/j.fct.2020.111472
   PubMed Web of Science ®Google Scholar
• Famurewa AC, Ekeleme-Egedigwe CA, Onwe CS, et al. Ginger juice prevents cisplatin-induced oxidative stress, endocrine imbalance and NO/iNOS/NF-κB signalling via modulating testicular redox-inflammatory mechanism in rats. Andrologia. 2020;52:e13786. doi:10.1111/and.13786
   PubMed Web of Science ®Google Scholar
• Fulco BC, Jung JT, Brum LO, Zborowski VA, Goulart TA, Nogueira CW. Similar hepatoprotective effectiveness of Diphenyl diselenide and Ebselen against cisplatin-induced disruption of metabolic homeostasis and redox balance in juvenile rats. Chem Biol Interact. 2020;330:109234. doi:10.1016/j.cbi.2020.109234
   PubMed Web of Science ®Google Scholar
• Gomaa DH, Hozayen WG, Al-shafeey H, Elkelawy AM, Hashem KS. Ginkgo biloba alleviates cisplatin-mediated neurotoxicity in rats via modulating APP/A/P2X7R/P2Y12R and XIAP/BDNF-dependent caspase-3 apoptotic pathway. Appl Sci. 2020;10:4786–4801. doi:10.3390/app10144786
   Google Scholar
• Sałat K. Chemotherapy-induced peripheral neuropathy: part 1—current state of knowledge and perspectives for pharmacotherapy. Pharmacol Rep. 2020;72:486–507. doi:10.1007/s43440-020-00109-y
   PubMed Web of Science ®Google Scholar
• Seigers R, Schagen S, Van Tellingen O, Dietrich J. Chemotherapy-related cognitive dysfunction: current animal studies and future directions. Brain Imaging Behav. 2013;7:453–459. doi:10.1007/s11682-013-9250-3
   PubMed Web of Science ®Google Scholar
• Morris RG, Garrud P, Rawlins JA, O’Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature. 1982;297:681–683. doi:10.1038/297681a0
   PubMed Web of Science ®Google Scholar
• Hao R, Song X, Li F, Tan X, Sun-Waterhouse D, Li D. Caffeic acid phenethyl ester reversed cadmium-induced cell death in hippocampus and cortex and subsequent cognitive disorders in mice: involvements of AMPK/SIRT1 pathway and amyloid-tau-neuroinflammation axis. Food Chem Toxicol. 2020;144:111636. doi:10.1016/j.fct.2020.111636
   PubMed Web of Science ®Google Scholar
• Wachiryah T, Hathaipat L. Enhancing effect of Tiliacora triandra leaves extract on spatial learning, memory and learning flexibility as well as hippocampal choline acetyltransferase activity in mice. Avicenna J Phytomed. 2018;8:380–388.
   PubMed Web of Science ®Google Scholar
• Ingkaninan K, Temkitthawon P, Chuenchom K, Yuyaem T, Thongnoi W. Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies. J Ethnopharmacol. 2003;89:261–264. doi:10.1016/j.jep.2003.08.008
   PubMed Web of Science ®Google Scholar
• Kandeil MA, Gomaa SB, Mahmoud MO. The effect of some natural antioxidants against cisplatin-induced neurotoxicity in rats: behavioral testing. Heliyon. 2020;6:e04708. doi:10.1016/j.heliyon.2020.e04708
   PubMed Web of Science ®Google Scholar
• Abdelkader NF, Saad MA, Abdelsalam RM. Neuroprotective effect of nebivolol against cisplatin-associated depressive-like behavior in rats. J Neurochem. 2017;141:449–460. doi:10.1111/jnc.13978
   PubMed Web of Science ®Google Scholar
• Oz M, Atalik KE, Yerlikaya FH, Demir EA. Curcumin alleviates cisplatin-induced learning and memory impairments. Neurobiol Learn Mem. 2015;123:43–49. doi:10.1016/j.nlm.2015.05.001
   PubMed Web of Science ®Google Scholar
• Eren H, Mercantepe T, Tumkaya L, et al. Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats. Exp Mol Pathol. 2020;112:104324. doi:10.1016/j.yexmp.2019.104324
   PubMed Web of Science ®Google Scholar
• Ueki M, Ueno M, Morishita J, Maekawa N. Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice. J Biosci Bioeng. 2013;115:547–551. doi:10.1016/j.jbiosc.2012.11.007
   PubMed Web of Science ®Google Scholar
• Famurewa AC, Edeogu CO, Offor FI, Besong EE, Akunna GG, Maduagwuna EK. Downregulation of redox imbalance and iNOS/NF-ĸB/caspase-3 signalling with zinc supplementation prevents urotoxicity of cyclophosphamide-induced hemorrhagic cystitis in rats. Life Sci. 2021;266:118913. doi:10.1016/j.lfs.2020.118913
   PubMed Web of Science ®Google Scholar
• Sohail N, Hira K, Kori JA, et al. Nephroprotective effect of ethanol extract and fractions of a sea lettuce, Ulva fasciata against cisplatin-induced kidney injury in rats. Environ Sci Pollut Res Int. 2021;28:9448–9461. doi:10.1007/s11356-020-11321-x
   PubMed Web of Science ®Google Scholar
• Yarijani ZM, Godini A, Madani SH, Najafi H. Reduction of cisplatin-induced renal and hepatic side effects in rat through antioxidative and anti-inflammatory properties of Malva sylvestris L. extract. Biomed Pharmacother. 2018;106:1767–1774. doi:10.1016/j.biopha.2018.07.115
   PubMed Web of Science ®Google Scholar
• Abdel-Razek EA, Abo-Youssef AM, Azouz AA. Benzbromarone mitigates cisplatin nephrotoxicity involving enhanced peroxisome proliferator-activated receptor-alpha (PPAR-α) expression. Life Sci. 2020;243:117272. doi:10.1016/j.lfs.2020.117272
   PubMed Web of Science ®Google Scholar
• Domitrovic R, Cvijanovic O, Šušnic V, Katalinic N. Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury. Toxicology. 2014;324:98–107. doi:10.1016/j.tox.2014.07.004
   PubMed Web of Science ®Google Scholar
• Kaygusuzoglu E, Caglayan C, Kandemir FM, et al. Zingerone ameliorates cisplatin‐induced ovarian and uterine toxicity via suppression of sex hormone imbalances, oxidative stress, inflammation and apoptosis in female Wistar rats. Biomed Pharmacother. 2018;102:517–530. doi:10.1016/j.biopha.2018.03.119
   PubMed Web of Science ®Google Scholar
• Hu J, Yang J, Jiang S, et al. Panax quinquefolium saponins protect against cisplatin evoked intestinal injury via ROS-mediated multiple mechanisms. Phytomedicine. 2021;82:153446. doi:10.1016/j.phymed.2020.153446
   PubMed Web of Science ®Google Scholar
• Weerawatanakorn M, Rojsuntornkitti K, Pan M, Wongwaiwech D. Some phytochemicals and anti-inflammation effect of juice from Tiliacora triandra leaves. J Food Nutr Res. 2018;6:32–38. doi:10.12691/jfnr-6-1-6
   Google Scholar
• Juckmeta T, Itharat A. Anti-inflammatory and antioxidant activities of Thai traditional remedy called ya-ha-rak. J Health Res. 2012;26:205–210.
   Google Scholar
• Arfaoui L. Dietary plant polyphenols: effects of food processing on their content and bioavailability. Molecules. 2021;26(10):2959. doi:10.3390/molecules26102959
   PubMed Web of Science ®Google Scholar
• Hano C, Tungmunnithum D. Plant polyphenols, more than just simple natural antioxidants: oxidative stress, aging and age-related diseases. Medicines. 2020;7:26. doi:10.3390/medicines7050026
   Google Scholar
• Pasachan T, Duangjai A, Ontawong A, et al. Tiliacora triandra (Colebr.) Diels leaf aqueous extract inhibits hepatic glucose production in HepG2 cells and type 2 diabetic rats. Molecules. 2021;26:1239. doi:10.3390/molecules26051239
   PubMed Web of Science ®Google Scholar
• Liu S, Zhang X, Wang J. Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses. Int Immunopharmacol. 2020;83:106437. doi:10.1016/j.intimp.2020.106437
   PubMed Web of Science ®Google Scholar
• Yu S, Yan H, Zhang L, et al. A review on the phytochemistry, pharmacology, and pharmacokinetics of amentoflavone, a naturally-occurring biflavonoid. Molecules. 2017;22:299. doi:10.3390/molecules22020299
   PubMed Web of Science ®Google Scholar
• Wang J, Fang X, Ge L, et al. Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol. PLoS One. 2018;13:e0197563. doi:10.1371/journal.pone.0197563
   PubMed Web of Science ®Google Scholar
• Pruccoli L, Morroni F, Sita G, Hrelia P, Tarozzi A. Esculetin as a bifunctional antioxidant prevents and counteracts the oxidative stress and neuronal death induced by amyloid protein in SH-SY5Y cells. Antioxidants. 2020;9:551. doi:10.3390/antiox9060551
   Web of Science ®Google Scholar
• Zhu L, Nang C, Luo F, et al. Esculetin attenuates lipopolysaccharide (LPS)-induced neuroinflammatory processes and depressive-like behavior in mice. Physiol Behav. 2016;163:184–192. doi:10.1016/j.physbeh.2016.04.051
   PubMed Web of Science ®Google Scholar