Establishment of a Stable Acute Drug-Induced Liver Injury Mouse Model by Sodium Cyclamate

References

• Syed M, Skonberg C, Hansen SH. Mitochondrial toxicity of diclofenac and its metabolites via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria: possible role in drug induced liver injury (Dili). Toxicol In Vitro. 2016;31:93–102. doi:10.1016/j.tiv.2015.11.020
   PubMed Web of Science ®Google Scholar
• Shen T, Liu Y, Shang J, et al. Incidence and etiology of drug-induced liver injury in Mainland China. Gastroenterology. 2019;156(8):2230–2241.e11. doi:10.1053/j.gastro.2019.02.002
   PubMed Web of Science ®Google Scholar
• Danjuma MI, Sajid J, Fatima H, Elzouki AN. Novel biomarkers for potential risk stratification of drug induced liver injury (Dili): a narrative perspective on current trends. Medicine. 2019;98(50):e18322. doi:10.1097/MD.0000000000018322
   PubMed Web of Science ®Google Scholar
• Leise MD, Poterucha JJ, Talwalkar JA. Drug-induced liver injury. Mayo Clin Proc. 2014;89(1):95–106. doi:10.1016/j.mayocp.2013.09.016
   PubMed Web of Science ®Google Scholar
• Sasaki YF, Kawaguchi S, Kamaya A, et al. The comet assay with 8 mouse organs: results with 39 currently used food additives. Mutat Res. 2002;519(1–2):103–119. doi:10.1016/s1383-5718(02)00128-6
   PubMed Web of Science ®Google Scholar
• Behrens M, Blank K, Meyerhof W. Blends of non-caloric sweeteners saccharin and cyclamate show reduced off-taste due to TAS2R bitter receptor inhibition. Cell Chem Biol. 2017;24(10):1199–1204.e2. doi:10.1016/j.chembiol.2017.08.004
   PubMed Web of Science ®Google Scholar
• Bopp BA, Sonders RC, Kesterson JW. Toxicological aspects of cyclamate and cyclohexylamine. Crit Rev Toxicol. 1986;16(3):213–306. doi:10.3109/10408448609037465
   PubMed Web of Science ®Google Scholar
• Hoppmann NA, Gray ME, McGuire BM. Drug-induced liver injury in the setting of chronic liver disease. Clin Liver Dis. 2020;24(1):89–106. doi:10.1016/j.cld.2019.09.006
   PubMed Web of Science ®Google Scholar
• Lai RT, Chen CW, Yu YC. Several issues worthy of reference and discussion of 2019 edition of the European Association for the Study of the Liver guideline for drug-induced liver injury. Zhonghua Gan Zang Bing Za Zhi. 2019;27(11):910–912. doi:10.3760/cma.j.issn.1007-3418.2019.11.018
   PubMedGoogle Scholar
• Suh JI. Drug-induced liver injury. Yeungnam Univ J Med. 2020;37(1):2–12. doi:10.12701/yujm.2019.00297
   PubMedGoogle Scholar
• Liu LW, Zhao XY, Jia JD. [EASL clinical practice guidelines recommendations for drug-induced liver injury in 2019]. Zhonghua Gan Zang Bing Za Zhi. 2019;27(6):420–423. Chinese. doi:10.3760/cma.j.issn.1007-3418.2019.06.006
   PubMedGoogle Scholar
• Sadoh WE, Eregie CO, Nwaneri DU, Sadoh AE. The diagnostic value of both troponin T and creatinine kinase isoenzyme (CK-MB) in detecting combined renal and myocardial injuries in asphyxiated infants. PLoS One. 2014;9(3):e91338. doi:10.1371/journal.pone.0091338
   PubMed Web of Science ®Google Scholar
• Zhang CJ, Pei XL, Song FY, et al. Early anthracycline-induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs-cTnT. Echocardiography. 2017;34(11):1593–1600. doi:10.1111/echo.13704
   PubMed Web of Science ®Google Scholar
• Ftouh S, Lewington A. Prevention, detection and management of acute kidney injury: concise guideline. Clin Med. 2014;14(1):61–65. doi:10.7861/clinmedicine.14-1-61
   PubMed Web of Science ®Google Scholar
• Li M, Sun Q, Li S, et al. Chronic restraint stress reduces carbon tetrachloride-induced liver fibrosis. Exp Ther Med. 2016;11(6):2147–2152. doi:10.3892/etm.2016.3205
   PubMed Web of Science ®Google Scholar
• Komolkriengkrai M, Nopparat J, Vongvatcharanon U, Anupunpisit V, Khimmaktong W. Effect of glabridin on collagen deposition in liver and amelioration of hepatocyte destruction in diabetes rats. Exp Ther Med. 2019;18(2):1164–1174. doi:10.3892/etm.2019.7664
   PubMed Web of Science ®Google Scholar
• Tian F, Liu Y, Gao J, et al. Study on the association between TGF-β1 and liver fibrosis in patients with hepatic cystic echinococcosis. Exp Ther Med. 2020;19(2):1275–1280. doi:10.3892/etm.2019.8355
   PubMed Web of Science ®Google Scholar
• Mohi-Ud-Din R, Mir RH, Sawhney G, Dar MA, Bhat ZA. Possible pathways of hepatotoxicity caused by chemical agents. Curr Drug Metab. 2019;20(11):867–879. doi:10.2174/1389200220666191105121653
   PubMed Web of Science ®Google Scholar
• Abd-Elhakim YM, Ghoneim MH, Khairy MH, Eissa SA. Single or combined protective and therapeutic impact of taurine and hesperidin on carbon tetrachloride-induced acute hepatic injury in rat. Environ Sci Pollut Res Int. 2020;27(12):13180–13193. doi:10.1007/s11356-020-07895-1
   PubMed Web of Science ®Google Scholar
• Rani V, Verma Y, Rana K, Rana SVS. Zinc oxide nanoparticles inhibit dimethylnitrosamine induced liver injury in rat. Chem Biol Interact. 2018;295:84–92. doi:10.1016/j.cbi.2017.10.009
   PubMed Web of Science ®Google Scholar
• Yang W, Hao Y, Hou W, et al. Jieduan-Niwan formula reduces liver apoptosis in a rat model of acute-on-chronic liver failure by regulating the E2F1-mediated intrinsic apoptosis pathway. Evid Based Complement Alternat Med. 2019;2019:8108503. doi:10.1155/2019/8108503
   PubMed Web of Science ®Google Scholar
• Lin L, Guan H, Li R, et al. Auriculatone sulfate effectively protects mice against acetaminophen-induced liver injury. Molecules. 2019;24(20):3642. doi:10.3390/molecules24203642
   PubMed Web of Science ®Google Scholar
• Durán Agüero S, Angarita Dávila L, Escobar Contreras MC, Rojas Gómez D, de Assis Costa J. Noncaloric sweeteners in children: a controversial theme. Biomed Res Int. 2018;2018:4806534. doi:10.1155/2018/4806534
   PubMed Web of Science ®Google Scholar
• Janvier S, Goscinny S, Le Donne C, Van Loco J. Low-calorie sweeteners in food and food supplements on the Italian market. Food Addit Contam Part B Surveill. 2015;8(4):298–308. doi:10.1080/19393210.2015.1094829
   PubMed Web of Science ®Google Scholar
• Arnold DL. Toxicology of saccharin. Fundam Appl Toxicol. 1984;4(5):674–685. doi:10.1016/0272-0590(84)90088-5
   PubMedGoogle Scholar
• Knowles MA, Jani H, Hicks RM. Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate. Carcinogenesis. 1986;7(5):767–774. doi:10.1093/carcin/7.5.767
   PubMed Web of Science ®Google Scholar
• Babbitt SE, Sutherland MC, San Francisco B, Mendez DL, Kranz RG. Mitochondrial cytochrome c biogenesis: no longer an enigma. Trends Biochem Sci. 2015;40(8):446–455. doi:10.1016/j.tibs.2015.05.006
   PubMed Web of Science ®Google Scholar
• Lin X, Huang R, Zhang S, et al. Methyl helicterate protects against CCl4-induced liver injury in rats by inhibiting oxidative stress, NF-κB activation, Fas/FasL pathway and cytochrome P4502E1 level. Food Chem Toxicol. 2012;50(10):3413–3420. doi:10.1016/j.fct.2012.07.053
   PubMed Web of Science ®Google Scholar
• Vincent JL; International Sepsis Forum. Hemodynamic support in septic shock. Intensive Care Med. 2001;27(Suppl 1):S80–S92. doi:10.1007/pl00003799
   PubMed Web of Science ®Google Scholar
• Aly H, Khashaba MT, El-Ayouty M, El-Sayed O, Hasanein BM. IL-1 beta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy. Brain Dev. 2006;28(3):178–182. doi:10.1016/j.braindev.2005.06.006
   PubMed Web of Science ®Google Scholar
• Zhang J, Patel MB, Griffiths R, et al. Tumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension. Hypertension. 2014;64(6):1275–1281. doi:10.1161/HYPERTENSIONAHA.114.03863
   PubMed Web of Science ®Google Scholar
• Vilaysane A, Chun J, Seamone ME, et al. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol. 2010;21(10):1732–1744. doi:10.1681/ASN.2010020143
   PubMed Web of Science ®Google Scholar