197
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Effect of Helicobacter Pylori Infection on Glucose Metabolism, Lipid Metabolism and Inflammatory Cytokines in Nonalcoholic Fatty Liver Disease Patients

, , , , &
Pages 1127-1135 | Received 05 Dec 2023, Accepted 27 Feb 2024, Published online: 14 Mar 2024

References

  • Cusi K, Isaacs S, Barb D, et al. American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD). Endocr Pract. 2022;28(5):528–562. doi:10.1016/j.eprac.2022.03.010
  • Younossi ZM. Non-alcoholic fatty liver disease - A global public health perspective. J Hepatol. 2019;70(3):531–544. doi:10.1016/j.jhep.2018.10.033
  • Estes C, Anstee QM, Arias-Loste MT, et al. Modeling MASLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016–2030. J Hepatol. 2018;69(4):896–904. doi:10.1016/j.jhep.2018.05.036
  • Younossi ZM, Tampi R, Priyadarshini M, Nader F. Burden of illness and economic model for patients with Non-Alcoholic Steatohepatitis (NASH) in the United States. Hepatology. 2018;69(2). doi:10.1002/hep.30254
  • Fan XF, Deng YQ, Wu GL. [Study on the distribution and characteristics of Chinese medicine syndrome in patients with nonalcoholic fatty liver disease]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011;31(10):1332–1336. Chinese.
  • Fierbinteanu Braticevici C, Sporea I, Panaitescu E, Tribus L. Value of acoustic radiation force impulse imaging elastography for non-invasive evaluation of patients with nonalcoholic fatty liver disease. Ultrasound Med Biol. 2013;39(11):1942–1950. doi:10.1016/j.ultrasmedbio.2013.04.019
  • Betancourt AM, King AL, Fetterman JL, et al. Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice. Biochem J. 2014;461(2):223–232. doi:10.1042/BJ20131433
  • Zheng JS, Xu A, Huang T, Yu X, Li D. Low docosahexaenoic acid content in plasma phospholipids is associated with increased non-alcoholic fatty liver disease in China. Lipids. 2012;47(6):549–556. doi:10.1007/s11745-012-3671-4
  • Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference [published correction appears in Hepatology. 2003 Aug;38(2):536]. Hepatology. 2003;37(5):1202–1219. doi:10.1053/jhep.2003.50193
  • Elliott C, Frith J, Day CP, Jones DE, Newton JL. Functional impairment in alcoholic liver disease and non-alcoholic fatty liver disease is significant and persists over 3 years of follow-up. Dig Dis Sci. 2013;58(8):2383–2391. doi:10.1007/s10620-013-2657-2
  • Masuda K, Ono M, Fukumoto M, et al. Usefulness of Technetium-99 m-2-methoxy-isobutyl-isonitrile liver scintigraphy for evaluating disease activity of non-alcoholic fatty liver disease. Hepatol Res. 2012;42(3):273–279. doi:10.1111/j.1872-034X.2011.00923.x
  • Polyzos SA, Kountouras J, Zavos C. Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines. Curr Mol Med. 2009;9(3):299–314. doi:10.2174/156652409787847191
  • Buzzetti E, Pinzani M, Tsochatzis EA. The multiple-hit pathogenesis of non-alcoholic fatty liver disease (MASLD). Metabolism. 2016;65(8):1038–1048. doi:10.1016/j.metabol.2015.12.012
  • Ahmed KS, Khan AA, Ahmed I, et al. Prevalence study to elucidate the transmission pathways of Helicobacter pylori at oral and gastroduodenal sites of a South Indian population. Singapore Med J. 2006;47(4):291–296.
  • Mladenova I, Durazzo M. Transmission of Helicobacter pylori. Minerva Gastroenterol Dietol. 2018;64(3):251–254. doi:10.23736/S1121-421X.18.02480-7
  • Tsay FW. Hsu PHPinfection and extra-gastroduode-nal diseases. J Biomed Sci. 2018;25(1):65. doi:10.1186/s12929-018-0469-6
  • Liu WZ, Xie Y, Lu H, et al. Fifth Chinese National Consensus Report on the management of Helicobacter pylori infection. Helicobacter. 2018;23(2):e12475. doi:10.1111/hel.12475
  • Wessler S, Krisch LM, Elmer DP, Aberger F. From inflammation to gastric cancer - the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases. Cell Commun Signal. 2017;15(1):15. doi:10.1186/s12964-017-0171-4
  • Lv NH, Xie C. Review and prospect of Helicobacter pylori infection research in China. Chin J Digest. 2021;41(4):217–220.
  • Hanafiah A, Lopes BS. Genetic diversity and virulence characteristics of Helicobacter pylori isolates in different human ethnic groups. Infect Genet Evol. 2020;78:104135. doi:10.1016/j.meegid.2019.104135
  • Li LN, Liu Y, Zhang HC, Wu T, Dai Y, Wang WH. Effect of Helicobacter pylori infection on inflammatory colorectal cancer induced by AOM/DSS in mice and its immune mechanism. Nat Med J China. 2020;100(34):2689–2695. doi:10.3760/cma.j.cn112137-20200112-00076
  • Wang J, Dong F, Su H, et al. H. pylori is related to NAFLD but only in female: a cross-sectional study. Int J Med Sci. 2021;18(11):2303–2311. doi:10.7150/ijms.50748
  • Tarantino G, Crocetto F, Di Vito C, et al. Association of MASLD and insulin resistance with non metastatic bladder cancer patients: a cross-sectional retrospective study. J Clin Med. 2021;10(2):346. doi:10.3390/jcm10020346
  • Zhu BB, Zhou HK, Bai XF, Liu Y, Li WP. Research progress on the relationship between Hp infection and non-alcoholic fatty liver disease. Hainan Med J. 2017;28(11):1833–1835.
  • Zhou BG, Yang HJ, Xu W, Wang K, Guo P, Ai YW. Association between Helicobacter pylori infection and nonalcoholic fatty liver disease: a systematic review and meta-analysis of observational studies. Helicobacter. 2019;24(3):e12576. doi:10.1111/hel.12576
  • Tang DM, Kumar S. The Association Between Helicobacter pylori infection and nonalcoholic fatty liver disease. Curr Gastroenterol Rep. 2017;19(2):5. doi:10.1007/s11894-017-0545-1
  • Polyzos SA, Kountouras J, Papatheodorou A, et al. Helicobacter pylori infection in patients with nonalcoholic fatty liver disease. Metabolism. 2013;62(1):121–126. doi:10.1016/j.metabol.2012.06.007
  • Fan JG, Wei L, Zhuang H. Guidelines of prevention and treatment for nonalcoholic fatty liver disease: a 2018 update. J Pract Hepatol. 2018;21(2):177–186.
  • Abdel-Razik A, Mousa N, Shabana W, et al. Helicobacter pylori and non-alcoholic fatty liver disease: a new enigma? Helicobacter. 2018;23(6):e12537. doi:10.1111/hel.12537
  • Chen C, Zhang C, Wang X, et al. Helicobacter pylori infection may increase the severity of nonalcoholic fatty liver disease via promoting liver function damage, glycometabolism, lipid metabolism, inflammatory reaction and metabolic syndrome. Eur J Gastroenterol Hepatol. 2020;32(7):857–866. doi:10.1097/MEG.0000000000001601
  • Wu QQ, Qin K, wang YJ. Central obesity is associated with helicobacter pylori infection: a large-scale cross-sectional retrospective study in West China. Int J Diabetes Dev Countries. 2019;40(2). doi:10.1007/s13410-019-00765-8
  • Kebapcilar L, Bilgir O, Cetinkaya E, Akyol M, Bilgir F, Bozkaya G. The effect of Helicobacter pylori eradication on macrophage migration inhibitory factor, C-reactive protein and fetuin-a levels. Clinics. 2010;65(8):799–802. doi:10.1590/s1807-59322010000800010
  • Cheng DD, He C, Ai HH, Huang Y, Lu NH. The possible role of helicobacter pylori infection in non-alcoholic fatty liver disease. Front Microbiol. 2017;8:743. doi:10.3389/fmicb.2017.00743
  • Chen CX, Mao YS, Foster P, Zhu ZW, Du J, Guo CY. Possible association between Helicobacter pylori infection and nonalcoholic fatty liver disease. Appl Physiol Nutr Metab. 2017;42(3):295–301. doi:10.1139/apnm-2016-0499
  • Nagura H, Ohtani H, Sasano H, Matsumoto T. The immuno-inflammatory mechanism for tissue injury in inflammatory bowel disease and Helicobacter pylori-infected chronic active gastritis. Roles of the mucosal immune system. Digestion. 2001;63(Suppl 1):12–21. doi:10.1159/000051905
  • Peverill W, Powell LW, Skoien R. Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation. Int J Mol Sci. 2014;15(5):8591–8638. doi:10.3390/ijms15058591
  • Ou HY, Yang YC, Wu HT, Wu JS, Lu FH, Chang CJ. Increased fetuin-A concentrations in impaired glucose tolerance with or without nonalcoholic fatty liver disease, but not impaired fasting glucose. J Clin Endocrinol Metab. 2012;97(12):4717–4723. doi:10.1210/jc.2012-2414
  • Li M, Shen Z, Li YM. Potential role of Helicobacter pylori infection in nonalcoholic fatty liver disease. World J Gastroenterol. 2013;19(41):7024–7031. doi:10.3748/wjg.v19.i41.7024
  • Boursier J, Mueller O, Barret M, et al. The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota. Hepatology. 2016;63(3):764–775. doi:10.1002/hep.28356
  • Včev A, Nakić D, Mrđen A, et al. Helicobacter pylori infection and coronary artery disease. Coll Antropol. 2007;31(3):757–760.
  • Chai Y, Guo N, Yao HX, et al. Effect of Helicobacter pylori eradication therapy on lipid metabolism and insulin resistance in non-alcoholic fatty liver disease. Chin J Nosocomiol. 2021;31(9):1319–1323.
  • Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444(7122):1027–1031. doi:10.1038/nature05414
  • Yang SX, Cai SL, Yang N, et al. Effect of Helicobacter pylori infection on glucose and lipid metabolism in patients with metabolic syndrome. Chin J Nosocomiol. 2021;31(20):3135–3138.
  • Tang WZ, Wang ZL, Wang XJ, et al. Study on the impact of Helicobacter pylori infection on glucose metabolism in patients with chronic hepatitis B cirrhosis. Chin J Nosocomiol. 2019;29(24):3715–3718.
  • Cox MJ, Turek EM, Hennessy C, et al. Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients. PLoS One. 2017;12(2):e0170622. doi:10.1371/journal.pone.0170622
  • Zhao JM, Yan XX, Li GX, et al. Characteristics of clinical feature in the patients with chronic obstructive pulmonary disease with bronchiectasis. IntJRespir. 2018;38(19):1460–1464.
  • Zhao W, Zhang ZP, Wang DY, et al. Study on the correlation between IL-18, hs-CRP, and TNF-α expression in patients with gastric cancer complicated by Helicobacter pylori infection. Chin J Nosocomiol. 2020;30(11):1651–1654.
  • Davarpanah E, Jafarzadeh A, Nemati M, et al. Circulating concentration of interleukin-37 in Helicobacter pylori-infected patients with peptic ulcer: its association with IL-37 related gene polymorphisms and bacterial virulence factor CagA. Cytokine. 2020;126:154928. doi:10.1016/j.cyto.2019.154928
  • He YK, Huang XL, Zhang XY, et al. Effect of vitamin D adjuvant therapy on serum levels of TNF-α, IL-6, and CRP in patients with non-alcoholic fatty liver disease. Hainan Med J. 2017;28(9):1481–1483.
  • Li X, Liu S, Luo J, et al. Helicobacter pylori induces IL-1β and IL-18 production in human monocytic cell line through activation of NLRP3 inflammasome via ROS signaling pathway. Pathog Dis. 2015;73(4):ftu024. doi:10.1093/femspd/ftu024
  • Liu Q, Meng X, Li Y, et al. Natural products for the prevention and management of Helicobacter pylori infection. Compr Rev Food Sci Food Saf. 2018;17(4):937–952. doi:10.1111/1541-4337.12355
  • Tarantino G, Balsano C, Santini SJ, et al. It is high time physicians thought of natural products for alleviating MASLD. is there sufficient evidence to use them? Int J Mol Sci. 2021;22(24):13424. doi:10.3390/ijms222413424
  • Gen R, Demir M, Ataseven H. Effect of Helicobacter pylori eradication on insulin resistance, serum lipids and low grade inflammation. South Med J. 2010;103(3):190–196. doi:10.1097/SMJ.ob0113e3181cf373f
  • Coronado MT, Pozzi AO, Punchard MA, González P, Fantidis P. Inflammation as a modulator of the HDL cholesterol induced inteleukin-10 production by human circulating mononuclear cells. Atherosclerosis. 2009;202(1):183–184. doi:10.1016/j.atherosclerosis.2008.03.015
  • Scharnagl H, Kist M, Grawitz AB, Koenig W, Wieland H, März W. Effect of Helicobacter pylori eradication on high density lipoprotein cholesterol. Am J Cardiol. 2004;93(2):219–220. doi:10.1016/j.amjcard.2003.09.045
  • Kanbay M, Gür G, Yücel M, Yilmaz U, Boyacioğlu S. Does eradication of Helicobacter pylori infection help normalize serum lipid and CRP levels? Dig Dis Sci. 2005;50(7):1228–1231. doi:10.1007/s10620-005-2764-9
  • Elizalde JI, Piqué JM, Moreno V, et al. Influence of Helicobacter pylori infection and eradication on blood lipids and fibrinogen. Aliment Pharmacol Ther. 2002;16(3):577–586. doi:10.1046/j.1365-2036.2002.01202.x
  • Zhang L, Gail MH, Wang YQ, et al. A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins. Am J Clin Nutr. 2006;84(4):912–919. doi:10.1093/ajcn/84.4.912
  • Wald NJ, Law MR, Morris JK, Bagnall AM. Helicobacter pylori infection and mortality from ischaemic heart disease: negative result from a large, prospective study. BMJ. 1997;315(7117):1199–1201. doi:10.1136/bmj.315.7117.1199