237
Views
21
CrossRef citations to date
0
Altmetric
Review

Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny approach

, , , , , , , , , , , & show all
Pages 1179-1189 | Published online: 08 Dec 2016

References

  • Di TellaMCastelliLColonnaFTheory of mind and emotional functioning in fibromyalgia syndrome: an investigation of the relationship between social cognition and executive functionPLoS One2015101e011654225594169
  • BurriAOgataSLivshitsGWilliamsFThe association between chronic widespread musculoskeletal pain, depression and fatigue is genetically mediatedPLoS One20151011e014028926599910
  • SmithSBReeniläIMännistöPTEpistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and painPain2014155112390239925218601
  • LeonardBEPain, depression and inflammation: are interconnected causative factors involved?Mod Trends Pharmacopsychiatri201530223526437055
  • Lorente-CebriánSCostaAGNavas-CarreteroSAn update on the role of omega-3 fatty acids on inflammatory and degenerative diseasesJ Physiol Biochem201571234134925752887
  • TickHNutrition and painPhys Med Rehabil Clin N Am201526230932025952067
  • MarxJCellular warriors at the Battle of the BulgeScience200329984684912574615
  • Alonso-AlonsoMWoodsSCPelchatMFood reward system: current perspectives and future research needsNutr Rev201573529630726011903
  • DavisCLevitanRDYilmazZKaplanASCarterJCKennedyJLBinge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypesProg Neuropsychopharmacol Biol Psychiatry201238232833522579533
  • HoustonMThe role of nutrition and nutraceutical supplements in the treatment of hypertensionWorld J Cardiol201462386624575172
  • HoustonMCThe role of nutrition, nutraceuticals, vitamins, antioxidants, and minerals in the prevention and treatment of hypertensionAltern Ther Health Med201319Suppl 13249
  • RajatSManishaSRobinSKumarSNutraceuticals: a reviewInt J Pharm2012349599
  • KapoorASharfsteinJMBreaking the gridlock: regulation of dietary supplements in the United StatesDrug Test Anal201683–442443027072846
  • ShanahanCJde LorimierRFrom science to finance – a tool for deriving economic implications from the results of dietary supplement clinical studiesJ Diet Suppl2016131163425166888
  • MisterSHathcockJUnder the law, FDA must grant different standards for new dietary ingredients and food additivesRegul Toxicol Pharmacol201262345645822310217
  • UmhauJCGargKWoodwardAMDietary supplements and their future in health care: commentary on draft guidelines proposed by the Food and Drug AdministrationAntioxid Redox Signal201216546146222181059
  • FDA (Food and Drug Administration) [webpage on the Internet]Draft guidance for industry: dietary supplements: new dietary ingredient notifications and related issues2011 Available from: http://www.fda.gov/regulatoryinformation/guidances/ucm257563.htmAccessed August 22, 2016
  • Institute of Medicine (US) Food ForumThe Human Microbiome, Diet, and Health: Workshop SummaryWashington, DCNational Academies Press (US)2013
  • TalatiARNew dietary ingredient notifications: a comprehensive review and strategies for avoiding FDA objectionsFood Drug Law J200762238739817632968
  • BealBRWallaceMSAn overview of pharmacologic management of chronic painMed Clin North Am20161001657926614720
  • JamisonRNMaoJOpioid analgesicsMayo Clin Proc201590795796826141334
  • CandrilliSDDavisKLIyerSImpact of constipation on opioid use patterns, health care resource utilization, and costs in cancer patients on opioid therapyJ Pain Palliat Care Pharmacother200923323124119670020
  • NelsonADCamilleriMChronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunitiesTherap Adv Gastroenterol201584206220
  • WanYCormanSGaoXLiuSPatelHModyREconomic burden of opioid-induced constipation among long-term opioid users with noncancer painAm Health Drug Benefits2015829310226005516
  • GaertnerJSiemensWCamilleriMDefinitions and outcome measures of clinical trials regarding opioid-induced constipation: a systematic reviewJ Clin Gastroenterol201549191625356996
  • JonesRPrommerEBackstedtDNaloxegol: a novel therapy in the management of opioid-induced constipationAm J Hosp Palliat Care Epub201576
  • DonnellySWalshDRybickiLThe symptoms of advanced cancer: identification of clinical and research priorities by assessment of prevalence and severityJ Palliat Care19951112732
  • WeitznerMAMoodyLNMcMillanSCSymptom management issues in hospice careAm J Hosp Palliat Care1997141901959295429
  • VainioAAuvinenAPrevalence of symptoms among patients with advanced cancer: an international collaborative studyJ Pain Symptom Manage1996123108718910
  • HatswellAJVegterSMeasuring quality of life in opioid-induced constipation: mapping EQ-5D-3 L and PAC-QOLHealth Econ Rev20156114
  • BellTAnnunziataKLeslieJBOpioid-induced constipation negatively impacts pain management, productivity, and health-related quality of life: findings from the National Health and Wellness SurveyJ Opioid Manag20095313714419662923
  • DornSLemboACremoniniFOpioid-induced bowel dysfunction: epidemiology, pathophysiology, diagnosis, and initial therapeutic approachAm J Gastroenterol2014213137
  • González CangaAFernández MartínezNSahagún PrietoAMDietary fiber and its interaction with drugsNutr Hosp201025453553920694287
  • StanghelliniVBellacosaLCogliandroRFiber and macrogol in the therapy of chronic constipationMinerva Gastroenetrol Dietol2013592217230
  • SlavinJLPosition of the American Dietetic Association: health implications of dietary fiberJ Am Diet Assoc2008108101716173118953766
  • DethlefsenLMcFall-NgaiMRelmanDAAn ecological and evolutionary perspective on human-microbe mutualism and diseaseNature2007449716481181817943117
  • LeyREHamadyMLozuponeCEvolution of mammals and their gut microbesScience200832058831647165118497261
  • TapJMondotSLevenezFTowards the human intestinal microbiota phylogenetic coreEnviron Microbiol200911102574258419601958
  • BlacklerRWGemiciBMankoAWallaceJLNSAID-gastroenteropathy: new aspects of pathogenesis and preventionCurr Opin Pharmacol201419111624929967
  • MontenegroLLosurdoGLicinioRNon steroidal anti-inflammatory drug induced damage on lower gastro-intestinal tract: is there an involvement of microbiota?Curr Drug Saf20149319620424809527
  • MatsuiHShimokawaOKanekoTNaganoYRaiKHyodoIThe pathophysiology of non-steroidal anti-inflammatory drug (NSAID)-induced mucosal injuries in stomach and small intestineJ Clin Biochem Nutr201148210711121373261
  • Remington-HobbsJPettsGHarrisTEmergency department management of undifferentiated abdominal pain with hyoscine butyl-bromide and paracetamol: a randomised control trialEmerg Med J2012291298999422307926
  • SavoiaGColuzziFDi MariaCItalian intersociety recommendations on pain management in the emergency setting (SIAARTI, SIMEU, SIS 118, AISD, SIARED, SICUT, IRC)Minerva Anestesiol201581220522524847740
  • NCD Risk Factor Collaboration (NCD-RisC)Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participantsLancet2016387100261377139627115820
  • NarouzeSSouzdalnitskiDObesity and chronic pain: opportunities for better patient carePain Manag20155421721926072666
  • OkifujiAHareBDThe association between chronic pain and obesityJ Pain Res2015839940826203274
  • McVinnieDSObesity and painBr J Pain20137416317026516520
  • HassanMKJoshiAVMadhavanSSAmonkarMMObesity and health-related quality of life: a cross-sectional analysis of the US populationInt J Obes2003271012271232
  • ArranzLIRafecasMAlegreCEffects of obesity on function and quality of life in chronic pain conditionsCurr Rheumatol Rep201416139024264719
  • RodriguezAEzquerroSMéndez-GiménezLBecerrilSFrühbeckGRevisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolismAm J Physiol Endocrinol Metab20153098E691E71426330344
  • WrightLJSchurENoonanCAhumadaSBuchwaldDAfariNChronic pain, overweight, and obesity: findings from a community-based twin registryJ Pain201011762863520338816
  • ZdziarskiLAWasserJGVincentHKChronic pain management in the obese patient: a focused review of key challenges and potential exercise solutionsJ Pain Res20158637725709495
  • MessierSPMihalkoSLLegaultCEffects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the idea randomized clinical trialJAMA2013310121263127324065013
  • TanamasSKWlukaAEBerryPRelationship between obesity and foot pain and its association with fat mass, fat distribution, and muscle massArthritis Care Res (Hoboken)201264226226821972207
  • AlbertazziPNon-estrogenic approaches for the treatment of climacteric symptomsClimacteric200710Suppl 211512017882686
  • LuoSLanTLiaoWZhaoMYangHGenistein inhibits Aβ25–35-induced neurotoxicity in PC12 cells via PKC signaling pathwayNeurochem Res201237122787279422949092
  • ValsecchiAEFranchiSPaneraiAERossiASacerdotePColleoniMThe soy isoflavone genistein reverses oxidative and inflammatory state, neuropathic pain, neurotrophic and vasculature deficits in diabetes mouse modelEur J Pharmacol20116502–369470221050844
  • ValsecchiAEFranchiSPaneraiAESacerdotePTrovatoAECol-leoniMGenistein, a natural phytoestrogen from soy, relieves neuropathic pain following chronic constriction sciatic nerve injury in mice: anti-inflammatory and antioxidant activityJ Neurochem2008107123024018691380
  • ShenCLSmithBJLoDFDietary polyphenols and mechanisms of osteoarthritisJ Nutr Biochem201223111367137722832078
  • TallJMRajaSNDietary constituents as novel therapies for painClin J Pain2004201192614668652
  • ZaheerKAkhtarMHAn updated review of dietary isoflavones: nutrition, processing, bioavailability and impacts on human healthCrit Rev Food Sci Nutr Epub20151113
  • McFadyenIJChettyUSetchellKDZimmer-NechemiasLStanleyEMillerWRA randomized double blind-cross over trial of soya protein for the treatment of cyclical breast painBreast20009527127614732177
  • Van PattenCLOlivottoIAChambersGKEffect of soy phytoestrogens on hot flashes in postmenopausal women with breast cancer: a randomized, controlled clinical trialJ Clin Oncol20022061449145511896091
  • Wahner-RoedlerDLThompsonJMLuedtkeCADietary soy supplement on fibromyalgia symptoms: a randomized, double-blind, placebo-controlled, early phase trialEvid Based Complement Alternat Med2011201135069718990724
  • ShirYRajaSNWeissmanCSCampbellJNSeltzerZConsumption of soy diet before nerve injury preempts the development of neuropathic pain in ratsAnesthesiology20019551238124411684996
  • SatijaAAhmedSMGuptaRBreast cancer pain management – a review of current & novel therapiesIndian J Med Res2014139221622524718395
  • ArjmandiBHKhalilDALucasEASoy protein may alleviate osteoarthritis symptomsPhytomedicine2004117–856757515636169
  • ThomasAJIsmailRTaylor-SwansonLEffects of isoflavones and amino acid therapies for hot flashes and co-occurring symptoms during the menopausal transition and early postmenopause: a systematic reviewMaturitas201478426327624951101
  • ZhaoCWacnikPWTallJMAnalgesic effects of a soy-containing diet in three murine bone cancer pain modelsJ Pain20045210411015042518
  • EngelPANew onset migraine associated with use of soy isoflavone supplementsNeurology20025981289129012391374
  • CalderPCMarine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevanceBiochim Biophys Acta20151851446948425149823
  • Lorente-CebriánSCostaAGNavas-CarreteroSZabalaMMartínezJAMoreno-AliagaMJRole of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: a review of the evidenceJ Physiol Biochem201369363365123794360
  • ParraDRamelABandarraNKielyMMartinezJAThorsdottirIA diet rich in long chain omega-3 fatty acids modulates satiety in overweight and obese volunteers during weight lossAppetite200851367668018602429
  • ThomasTRLiuYLindenMARectorRSInteraction of exercise training and n-3 fatty acid supplementation on postprandial lipemiaAppl Physiol Nutr Metab200732347348017510682
  • HillAMBuckleyJDMurphyKJHowePRCombining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factorsAm J Clin Nutr20078551267127417490962
  • HuertaAEPrieto-HontoriaPLSáinzNMartínezJAMoreno-AliagaMJSupplementation with α-lipoic acid alone or in combination with eicosapentaenoic acid modulates the inflammatory status of healthy overweight or obese women consuming an energy-restricted dietJ Nutr Epub201639
  • KunesovaMBraunerovaRHlavatyPThe influence of n−3 polyunsaturated fatty acids and very low calorie diet during a short-term weight reducing regimen on weight loss and serum fatty acid composition in severely obese womenPhysiol Res200655637215857162
  • BuckleyJDHowePRLong-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity-a reviewNutrients20102121212123022254005
  • MoriTABurkeVPuddeyIBPurified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic menAm J Clin Nutr20007151085109410799369
  • MoriTAWattsGFBurkeVHilmeEPuddeyIBBeilinLJDifferential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight menCirculation2000102111264126910982541
  • MoriTAWoodmanRJThe independent effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors in humansCurr Opin Clin Nutr Metab Care2006929510416477172
  • TsitourasPDGucciardoFSalbeADHewardCHarmanSMHigh omega-3 fat intake improves insulin sensitivity and reduces CRP and IL6, but does not affect other endocrine axes in healthy older adultsHorm Metab Res200840319920518348080
  • DerosaGCiceroAD’AngeloABorghiCMaffioliPEffects of n-3 pufas on fasting plasma glucose and insulin resistance in patients with impaired fasting glucose or impaired glucose toleranceBiofactors201642331632227040503
  • EspositoKMarfellaRCiotolaMEffect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trialJAMA2004292121440144615383514
  • RamelAMartinezAKielyMMoraisGBandarraNMThorsdottirIBeneficial effects of long-chain n−3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adultsDiabetologia2008511261126818491071
  • AbeteIGoyenecheaEZuletMAMartínezJAObesity and metabolic syndrome: potential benefit from specific nutritional componentsNutr Metab Cardiovasc Dis201121Suppl 2B1B1521764273
  • Lopez-AlvarengaJCEbbessonSOEbbessonLOTejeroMEVorugantiVSComuzzieAGPolyunsaturated fatty acids effect on serum triglycerides concentration in the presence of metabolic syndrome components. The Alaska-Siberia ProjectMetabolism2010591869219766268
  • NestelPShigeHPomeroySCehunMAbbeyMRaederstorffDThe n−3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humansAm J Clin Nutr20027632633012145002
  • KabirMSkurnikGNaourNTreatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled studyAm J Clin Nutr20078661670167918065585
  • MicallefMAGargMLThe lipid-lowering effects of phytosterols and (n−3) polyunsaturated fatty acids are synergistic and complementary in hyperlipidemic men and womenJ Nutr20081381086109018492838
  • MicallefMMunroIPhangMGargMPlasma n-3 polyunsaturated fatty acids are negatively associated with obesityBr J Nutr20091021370137419454127
  • JainAPAggarwalKKZhangPYOmega-3 fatty acids and cardiovascular diseaseEur Rev Med Pharmacol Sci201519344144525720716
  • MunroIAGargMLDietary supplementation with n–3 PUFA does not promote weight loss when combined with a very-low-energy dietBr J Nutr201210881466147422214842
  • BurrMLAshfield-WattPADunstanFDLack of benefit of dietary advice to men with angina: results of a controlled trialEur J Clin Nutr200357219320012571649
  • ThompkinsonDKBhavanaVKanikaPDietary approaches for management of cardio-vascular health-a reviewJ Food Sci Technol201451102318233025328172
  • Del GobboLCImamuraFAslibekyanSCohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe)ω-3 polyunsaturated fatty acid biomarkers and coronary heart disease: pooling project of 19 cohort studiesJAMA Intern Med201617681155116627357102
  • TavazziLMaggioniAPMarchioliRGissi-HF InvestigatorsEffect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trialLancet200837296451223123018757090
  • YokoyamaMOrigasaHMatsuzakiMJapan EPA lipid intervention study (JELIS) InvestigatorsEffects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysisLancet200736995671090109817398308
  • EstruchRRosESalas-SalvadóJPREDIMED Study InvestigatorsPrimary prevention of cardiovascular disease with a Mediterranean dietN Engl J Med2013368141279129023432189
  • Sala-VilaAGuasch-FerréMHuFBDietary α-linolenic acid, marine ω-3 fatty acids, and mortality in a population with high fish consumption: findings from the PRevención con Dieta MEDiterránea (PREDIMED) StudyJ Am Heart Assoc201651e00254326813890
  • LeafAAlbertCMJosephsonMPrevention of fatal arrhythmias in high-risk subjects by fish oil n−3 fatty acid intakeCirculation20051122762276816267249
  • MozaffarianDFish, mercury, selenium and cardiovascular risk: current evidence and unanswered questionsInt J Environ Res Public Health2009661894191619578467
  • CaloLBianconiLColivicchiFn−3 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a randomized, controlled trialJ Am Coll Cardiol2005451723172815893193
  • DallongevilleJYarnellJDucimetierePFish consumption is associated with lower heart ratesCirculation2003108782082512912821
  • Kris-EthertonPMHarrisWSAppelLJFish consumption, fish oil, omega-3 fatty acids, and cardiovascular diseaseCirculation20021062747275712438303
  • Kris-EthertonPMInnisSAmerican Dietetic Association, Dietitians of CanadaPosition of the American Dietetic Association and Dietitians of Canada: dietary fatty acidsJ Am Diet Assoc200710791599161117936958
  • GeleijnseJMGiltayEJGrobbeeDEDondersARKokFJBlood pressure response to fish oil supplementation: metaregression analysis of randomized trialsJ Hypertens20022081493149912172309
  • HartwegJFarmerAJPereraRHolmanRRNeilHAMeta-analysis of the effects of n−3 polyunsaturated fatty acids on lipoproteins and other emerging lipid cardiovascular risk markers in patients with type 2 diabetesDiabetologia2007501593160217541540
  • UeshimaHStamlerJElliottPINTERMAP Research GroupFood omega-3 fatty acid intake of individuals (total, linolenic acid, long-chain) and their blood pressure: INTERMAP studyHypertension200750231331917548718
  • DullemeijerCDurgaJBrouwerIAn 3 fatty acid proportions in plasma and cognitive performance in older adultsAm J Clin Nutr20078651479148517991662
  • van GelderBMTijhuisMKalmijnSKromhoutDFish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly StudyAm J Clin Nutr20078541142114717413117
  • NurkEDrevonCARefsumHCognitive performance among the elderly and dietary fish intake: the Hordaland Health StudyAm J Clin Nutr20078651470147817991661
  • BeydounMAKaufmanJSSatiaJARosamondWFolsomARPlasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities StudyAm J Clin Nutr20078541103111117413112
  • Freund LeviYVedinICederholmTTransfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer’s disease: the OmegAD studyJ Intern Med201427542843624410954
  • Freund-LeviYEriksdotter-JonhagenMCederholmTOmega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trialArch Neurol200663101402140817030655
  • Freund-LeviYVedinIHjorthEEffects of supplementation with omega-3 fatty acids on oxidative stress and inflammation in patients with Alzheimer’s disease: the OmegAD studyJ Alzheimers Dis20144282383124934544
  • QuinnJFRamanRThomasRGDocosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trialJAMA2010304171903191121045096
  • ShintoLQuinnJMontineTA randomized placebo controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer’s diseaseJ Alzheimers Dis20143811112024077434
  • SamieriCFeartCLetenneurLLow plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia riskAm J Clin Nutr200888371472118779288
  • MarcheselliVLMukherjeePKAritaMNeuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophilsProstaglandins Leukot Essent Fatty Acids2010821273419931440
  • LukiwWJCuiJGMarcheselliVLA role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer diseaseJ Clin Invest2005115102774278316151530
  • EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)Scientific opinion on the re-evaluation of curcumin (E 100) as a food additiveEFSA Journal2010891679
  • AggarwalBBGuptaSCSungBCurcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkersBr J Pharmacol201316981672169223425071
  • ChandranBGoelAA randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritisPhytother Res201226111719172522407780
  • RamadanGEl-MenshawyOProtective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritisInt J Rheum Dis201316221922923773648
  • ZhuXLiQChangRCurcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat modelPLoS One201493e9130324603592
  • ZhaoXXuYZhaoQChenCRLiuAMHuangZLCurcumin exerts antinociceptive effects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are differentially involvedNeuropharmacology201262284385421945716
  • JiFTLiangJJLiuLCaoMHLiFCurcumin exerts antinociceptive effects by inhibiting the activation of astrocytes in spinal dorsal horn and the intracellular extracellular signal-regulated kinase signaling pathway in rat model of chronic constriction injuryChin Med J (Engl)201312661125113123506591
  • HuXHuangFSzymusiakMLiuYWangZJCurcumin attenuates opioid tolerance and dependence by inhibiting Ca2+/calmodulin-dependent protein kinase II α activityJ Pharmacol Exp Ther2015352342042825515789
  • HuXHuangFSzymusiakMTianXLiuYWangZJPLGA-curcumin attenuates opioid-induced hyperalgesia and inhibits spinal CaMKIIαPLoS One2016111e014639326744842
  • KhopdeSMPriyadarsiniKIVenkatesanNRaoMNAFree radical scavenging ability and anti-oxidant efficiency of curcumin and its substituted analogueBiophys Chem19998028389
  • HosseinzadehdehkordiMAdelinikATashakorADual effect of curcumin targets reactive oxygen species, adenosine triphosphate contents and intermediate steps of mitochondria-mediated apoptosis in lung cancer cell linesEur J Pharmacol201576920321026593433
  • González-ReyesSGuzmán-BeltránSMedina-CamposONPedraza-ChaverriJCurcumin pretreatment induces Nrf2 and an antioxidant response and prevents hemin-induced toxicity in primary cultures of cerebellar granule neurons of ratsOxid Med Cell Longev2013201380148018
  • LoneJChoiJHKimSWYunJWCurcumin induces brown fat-like phenotype in 3T3-L1 and primary white adipocytesJ Nutr Biochem20162719320226456563
  • TeitenMHDicatoMDiederichMCurcumin as a regulator of epigenetic eventsMol Nutr Food Res20135791619162923754571
  • AnandPKunnumakkaraABNewmanRAAggarwalBBBioavailability of curcumin: problems and promisesMol Pharm20074680781817999464
  • ElSNKarakayaSOlive tree (Olea europaea) leaves: potential beneficial effects on human healthNutr Rev2009671163263819906250
  • MollaceVRagusaSSaccoIThe protective effect of bergamot oil extract on lecitine-like oxyLDL receptor-1 expression in balloon injury-related neointima formationJ Cardiovasc Pharmacol Ther200813212012918413898
  • Di DonnaLDe LucaGMazzottiFStatin-like principles of bergamot fruit (Citrus bergamia): isolation of 3-hydroxymethylglutaryl flavonoid glycosidesJ Nat Prod20097271352135419572741
  • MollaceVSaccoIJandaEHypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studiesFitoterapia201182330931621056640
  • GliozziMWalkerRMuscoliSBergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemiaInt J Cardiol2013170214014524239156
  • MuscoliCLauroFDagostinoCOlea europaea-derived phenolic products attenuate antinociceptive morphine tolerance: an innovative strategic approach to treat cancer painJ Biol Regul Homeost Agents201428110511624750796
  • LauroFIlariSGiancottiLAThe protective role of bergamot polyphenolic fraction on several animal models of painPharmaNutritionIn press2016
  • SalveminiDLittleJWDoyleTNeumannWLRoles of reactive oxygen and nitrogen species in painFree Radic Biol Med201151595196621277369
  • LauroFGiancottiLAIlariSInhibition of spinal oxidative stress by bergamot polyphenolic fraction attenuates the development of morphine induced tolerance and hyperalgesia in micePLoS One2016115e015603927227548